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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEPT11 Gene

protein-coding   GIFtS: 53
GCID: GC04P077870

Septin 11

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Septin 111 2
septin-112

External Ids:    HGNC: 255891   Entrez Gene: 557522   Ensembl: ENSG000001387587   OMIM: 6128875   UniProtKB: Q9NVA23   

Export aliases for SEPT11 gene to outside databases

Previous GC identifers: GC04P078330 GC04P078229 GC04P078089 GC04P073622


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SEPT11 Gene:
SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a
variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 (PubMed
15196925); Nagata et al., 2004 (PubMed 15485874)).(supplied by OMIM, Jul 2009)

GeneCards Summary for SEPT11 Gene: 
SEPT11 (septin 11) is a protein-coding gene. Diseases associated with SEPT11 include hereditary neuralgic amyotrophy, and chronic neutrophilic leukemia. GO annotations related to this gene include protein binding and GTP binding. An important paralog of this gene is SEPT3.

UniProtKB/Swiss-Prot: SEP11_HUMAN, Q9NVA2
Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the
cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic
connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry
process, but restricts its efficacy

Gene Wiki entry for SEPT11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEPT11 gene promoter:
         SREBP-1c   MyoD   AP-4   SREBP-1b   POU2F1   SREBP-1a   HNF-1   POU2F1a   Chx10   Zic3   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SEPT11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEPT11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.1   Ensembl cytogenetic band:  4q21.1   HGNC cytogenetic band: 4q21.1

SEPT11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEPT11 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P077870:  view genomic region     (about GC identifiers)

Start:
77,870,856 bp from pter      End:
77,961,537 bp from pter
Size:
90,682 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SEP11_HUMAN, Q9NVA2 (See protein sequence)
Recommended Name: Septin-11  
Size: 429 amino acids; 49398 Da
Subunit: Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with
cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation.
Interacts with SEPT7, SEPT9 and SEPT12. Forms homooligomers
Subcellular location: Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell
projection, axon (By similarity). Note=Partly colocalizes with stress fibers and microtubules. During bacterial
infection, displays a collar shape structure next to actin at the pole of invading bacteria
Sequence caution: Sequence=BAB55250.1; Type=Erroneous initiation; Sequence=CAB53741.2; Type=Miscellaneous
discrepancy; Note=Contaminating sequence. Potential poly-A sequence;
Secondary accessions: B7Z7Z6 E9KL32 Q4W5G1 Q7L4N1 Q96SP1 Q9UFY9
Alternative splicing: 2 isoforms:  Q9NVA2-1   Q9NVA2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SEPT11: NX_Q9NVA2

Explore proteomics data for SEPT11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NVA2

  • SEPT11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SEPT11 Protein Expression
    REFSEQ proteins: NP_060713.1  
    ENSEMBL proteins: 
     ENSP00000264893   ENSP00000426344   ENSP00000420839   ENSP00000424925   ENSP00000422896  
     ENSP00000425262   ENSP00000422047   ENSP00000423103   ENSP00000424122   ENSP00000443701  

    Human Recombinant Protein Products for SEPT11: 
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001725stress fiber IDA15485874
    GO:0005737cytoplasm IDA--
    GO:0030054cell junction IEA--
    GO:0030424axon IEA--
    GO:0031105septin complex IEA--

    SEPT11 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SEPT: Septins

    3 InterPro protein domains:
     IPR000038 Cell_div_GTP-bd
     IPR027417 P-loop_NTPase
     IPR016491 Septin

    Graphical View of Domain Structure for InterPro Entry Q9NVA2

    ProtoNet protein and cluster: Q9NVA2

    1 Blocks protein domain: IPB000038 Cell division/GTP binding protein

    UniProtKB/Swiss-Prot: SEP11_HUMAN, Q9NVA2
    Similarity: Belongs to the septin family


    SEPT11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SEP11_HUMAN, Q9NVA2
    Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the
    cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic
    connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry
    process, but restricts its efficacy

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15485874
    GO:0005525GTP binding IEA--
         
    SEPT11 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SEPT11 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SEPT11

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SEPT11 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SEPT11 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Bacterial invasion of epithelial cells
    Bacterial invasion of epithelial cells

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for SEPT11):
        Bacterial invasion of epithelial cells


    SEPT11 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEPT11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/19 Interacting proteins for SEPT11 (Q9NVA21, 3 ENSP000002648934) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SEPT5Q997191, 3, ENSP000003913114EBI-957999,EBI-373345 I2D: score=2 STRING: ENSP00000391311
    SEPT7Q161813, ENSP000003819924I2D: score=3 STRING: ENSP00000381992
    SEPT9Q9UHD83, ENSP000003912494I2D: score=2 STRING: ENSP00000391249
    SEPT2Q150193, ENSP000003531574I2D: score=1 STRING: ENSP00000353157
    SEPT1Q8WYJ63, ENSP000003245114I2D: score=1 STRING: ENSP00000324511
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle IEA--
    GO:0051291protein heterooligomerization IDA15485874
    GO:0051301cell division IEA--

    SEPT11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SEPT11 (SEP11)

    Search CenterWatch for drugs/clinical trials and news about SEPT11 / SEP11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SEPT11 gene: 
    NM_018243.2  

    Unigene Cluster for SEPT11:

    Septin 11
    Hs.128199  [show with all ESTs]
    Unigene Representative Sequence: CR627457
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264893(uc003hkj.3 uc011cca.2) ENST00000502584 ENST00000510641(uc010ijh.1)
    ENST00000505788 ENST00000512575 ENST00000510515 ENST00000504637 ENST00000512778
    ENST00000512333 ENST00000504460 ENST00000506047(uc003hkk.1) ENST00000506731
    ENST00000502401 ENST00000513373 ENST00000513697 ENST00000515671 ENST00000541121

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/93 QIAGEN miScript miRNA Assays for microRNAs that regulate SEPT11 (see all 93):
    hsa-miR-3678-3p hsa-miR-3938 hsa-miR-300 hsa-miR-15a hsa-miR-485-3p hsa-miR-3074-3p hsa-miR-342-3p hsa-miR-1304
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    Additional mRNA sequence: 

    AK001711.1 AK027279.1 AK027633.1 AK094473.1 AK124592.1 AK302700.1 AL110300.1 BC008083.2 
    BC063615.1 BC064934.1 BX648411.1 CR627457.1 GU727629.1 

    24/35 DOTS entries (see all 35):

    DT.100885359  DT.102839659  DT.214465  DT.218079  DT.121254547  DT.75100653  DT.91772453  DT.121254690 
    DT.100885349  DT.121254674  DT.100885366  DT.100044828  DT.91765025  DT.121254618  DT.409874  DT.40110509 
    DT.453243  DT.91772457  DT.92027843  DT.95251735  DT.100725134  DT.100885346  DT.121254587  DT.121254597 

    24/473 AceView cDNA sequences (see all 473):

    BF063385 BU070312 BQ026881 BE501876 BM989346 AA347109 AK027633 N59663 
    BG426417 CR609711 CB108824 AA340872 BU500857 AA374538 BU542280 F13051 
    AA970278 CB132488 BC063615 BP337471 BQ226874 AI538005 BM475531 AI079352 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SEPT11 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16
    SP1:                                      -     -                 -                                               -                           
    SP2:                    -     -     -     -     -                 -                                               -                           
    SP3:                                                              -                                                                           
    SP4:                    -     -     -     -     -                 -                                                                           
    SP5:                                            -                 -                                                                           


    ECgene alternative splicing isoforms for SEPT11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SEPT11 expression in normal human tissues (normalized intensities)      SEPT11 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SEPT11 Expression
    About this image


    SEPT11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Blood (Hematopoietic System)
             Natural Killer Cells Peripheral Blood

    See SEPT11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SEPT11

    SOURCE GeneReport for Unigene cluster: Hs.128199

    UniProtKB/Swiss-Prot: SEP11_HUMAN, Q9NVA2
    Tissue specificity: Widely expressed, except in leukocytes

        SABiosciences Custom PCR Arrays for SEPT11
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SEPT11 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sept111 , 5 septin 111, 5 89.02(n)1
    99.77(a)1
      5 (47.29 cM)5
    523981  NM_001009818.11  NP_001009818.11 
     930934575 
    chicken
    (Gallus gallus)
    Aves SEPT111 septin 11 83.41(n)
    97.41(a)
      422635  XM_420591.3  XP_420591.2 
    lizard
    (Anolis carolinensis)
    Reptilia SEPT116
    septin 11
    97(a)
    1 ↔ 1
    5(146258438-146379320)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.253422 Xenopus laevis transcribed sequence with moderate similarity more 80.1(n)    BU916194.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sept8b1 septin 8b 71.59(n)
    77.14(a)
      571702  NM_001083566.1  NP_001077035.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Sep21 Septin-2 66.75(n)
    73.39(a)
      42438  NM_079693.3  NP_524417.1 
    worm
    (Caenorhabditis elegans)
    Secernentea unc-611 Protein UNC-61 52.91(n)
    48.15(a)
      179976  NM_001047733.1  NP_001041198.1 


    ENSEMBL Gene Tree for SEPT11 (if available)
    TreeFam Gene Tree for SEPT11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SEPT11 gene
    SEPT32  SEPT92  SEPT142  SEPT42  SEPT12  SEPT122  SEPT72  ENSG000002704662  
    SEPT62  SEPT22  SEPT102  SEPT82  SEPT52  
    17 SIMAP similar genes for SEPT11 using alignment to 8 protein entries:     SEP11_HUMAN (see all proteins):
    SEPT6    SEPT10    SEPT8    DKFZp547B243    DKFZp564M1416    SEPT14
    SEPT9    MAFK    SEPT2    SEPT3    SEPT7    DKFZp686F17268
    Nbla02942    SEPT1    SEPT12    SEPT5    SEPT4

    SEPT11 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1612 SNPs in SEPT11 are shown (see all 1612)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1839313781,2
    --77869056(+) TTTTTA/TAGAGC 1 -- us2k10--------
    rs1479379981,2
    --77869103(+) AGGTGC/TTGGGA 1 -- us2k10--------
    rs1886027481,2
    --77869454(+) CGCCCA/GGGGAC 1 -- us2k10--------
    rs3727222051,2
    C--77869455(+) GCCCGA/GGGACG 1 -- us2k10--------
    rs38067271,2
    C--77869532(+) GGACAG/AGGAGA 1 -- us2k12Minor allele frequency- A:0.00NA 4
    rs1918701671,2
    --77869545(+) CAAGGC/TCCCAG 1 -- us2k10--------
    rs1179840901,2
    F--77869630(+) TTCAGG/AAGGCC 1 -- us2k11Minor allele frequency- A:0.01EA 120
    rs752729311,2
    F--77869872(+) GACACG/CCAGTA 1 -- us2k11Minor allele frequency- C:0.04NA 120
    rs726651101,2
    C,F--77870028(+) GTCGCC/GGGGTC 1 -- us2k12Minor allele frequency- G:0.06NA 122
    rs1157921181,2
    F--77870078(+) TGTGGC/TTGCTC 1 -- us2k11Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for SEPT11 (77870856 - 77961537 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SEPT11:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv829973CNV Loss17160897
    nsv7363OTHER Inversion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612887    OMIM disorders: --

    UniProtKB/Swiss-Prot: SEP11_HUMAN, Q9NVA2
  • Note=A chromosomal aberration involving SEPT11 may be a cause of chronic neutrophilic leukemia.
    Translocation t(4;11)(q21;q23) with KMT2A/MLL1

  • 9 diseases for SEPT11:    About MalaCards
    hereditary neuralgic amyotrophy    chronic neutrophilic leukemia    epididymitis    choroiditis
    retinitis    hepatocellular carcinoma    endotheliitis    leukemia
    neuronitis


    SEPT11 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SEPT11
    Human Genome Epidemiology (HuGE) Navigator: SEPT11 (1 document)

    Export disorders for SEPT11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SEPT11 gene, integrated from 9 sources (see all 45):
    (articles sorted by number of sources associating them with SEPT11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23). (PubMed id 14999297)1, 2, 3 Kojima K.... Fujita S. (2004)
    2. Septin 11 restricts InlB-mediated invasion by Listeria. (PubMed id 19234302)1, 2, 9 Mostowy S....Cossart P. (2009)
    3. Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins. (PubMed id 20736409)1, 2 Li J.... Liu Y. (2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling. (PubMed id 17546647)1, 2 Sudo K....Nagata K. (2007)
    6. Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11. (PubMed id 15485874)1, 2 Nagata K....Inagaki M. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Biochemical and cell biological characterization of a mammalian septin, Sept11. (PubMed id 15196925)1, 2 Hanai N....Inagaki M. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. Analysis of mammalian septin expression in human malignant brain tumors. (PubMed id 15140406)1, 3 Kim D.S....Rutka J.T. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55752 HGNC: 25589 AceView: SEPT11 Ensembl:ENSG00000138758 euGenes: HUgn55752
    ECgene: SEPT11 Kegg: 55752 H-InvDB: SEPT11

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SEPT11 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SEPT11 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SEPT11 gene:
    Search GeneIP for patents involving SEPT11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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