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SEPT10 Gene

protein-coding   GIFtS: 50
GCID: GC02M110300

Septin 10

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Septin 101 2
sept1-like1
septin-102

External Ids:    HGNC: 143491   Entrez Gene: 1510112   Ensembl: ENSG000001865227   OMIM: 6117375   UniProtKB: Q9P0V93   

Export aliases for SEPT10 gene to outside databases

Previous GC identifers: GC02M109850 GC02M109912 GC02M109657 GC02M103756


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SEPT10 Gene:
This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein
localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. A pseudogene for this gene
is located on chromosome 8. Alternative splicing results in multiple transcript variants. (provided by RefSeq,
Apr 2012)

GeneCards Summary for SEPT10 Gene:
SEPT10 (septin 10) is a protein-coding gene. Diseases associated with SEPT10 include b-cell chronic lymphocytic leukemia, and chronic lymphocytic leukemia. GO annotations related to this gene include GTP binding. An important paralog of this gene is SEPT3.

UniProtKB/Swiss-Prot: SEP10_HUMAN, Q9P0V9
Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SEPT10 gene promoter:
         LHX3b/Lhx3b   Lmo2   MyoD   IRF-1   Nkx2-5   C/EBPalpha   IRF-7A   LHX3a/Lhx3a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SEPT10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SEPT10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q13   Ensembl cytogenetic band:  2q13   HGNC cytogenetic band: 2q13

SEPT10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEPT10 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M110300:  view genomic region     (about GC identifiers)

Start:
110,300,376 bp from pter      End:
110,371,783 bp from pter
Size:
71,408 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SEP10_HUMAN, Q9P0V9 (See protein sequence)
Recommended Name: Septin-10  
Size: 454 amino acids; 52593 Da
Subunit: Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with
cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By
similarity)
Sequence caution: Sequence=AAF67469.1; Type=Frameshift; Positions=444;
Secondary accessions: B3KRQ9 Q86VP5 Q9HAH6
Alternative splicing: 3 isoforms:  Q9P0V9-1   Q9P0V9-2   Q9P0V9-3   (Ref.2 (AAH50345) sequence differs from that shown due to a frameshift in position 503)

Explore the universe of human proteins at neXtProt for SEPT10: NX_Q9P0V9

Explore proteomics data for SEPT10 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SEPT10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_653311.1  NP_848699.1  

    ENSEMBL proteins: 
     ENSP00000349116   ENSP00000380824   ENSP00000380826   ENSP00000407790   ENSP00000396728  
     ENSP00000446331   ENSP00000399270   ENSP00000445707   ENSP00000416597   ENSP00000441218  
     ENSP00000396051   ENSP00000408392   ENSP00000334234   ENSP00000439364  

    SEPT10 Human Recombinant Protein Products:

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    Novus Biologicals SEPT10 Protein
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    Browse Sino Biological Cell Lysates
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    Browse Proteins at Cloud-Clone Corp.

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SEPT: Septins

    3 InterPro protein domains:
     IPR016491 Septin
     IPR000038 Cell_div_GTP-bd
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q9P0V9

    ProtoNet protein and cluster: Q9P0V9

    1 Blocks protein domain: IPB000038 Cell division/GTP binding protein

    UniProtKB/Swiss-Prot: SEP10_HUMAN, Q9P0V9
    Similarity: Belongs to the septin family


    SEPT10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SEP10_HUMAN, Q9P0V9
    Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005525GTP binding IEA--
         
    SEPT10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SEPT10:
     Decreased cilium length after  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SEPT10
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    miRNA
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    miRTarBase miRNAs that target SEPT10:
    hsa-mir-192-5p (MIRT004860), hsa-mir-100-5p (MIRT048467), hsa-mir-215-5p (MIRT024302)

    Block miRNA regulation of human, mouse, rat SEPT10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SEPT10 (see all 28):
    hsa-miR-3910 hsa-miR-875-3p hsa-miR-4328 hsa-miR-4251 hsa-miR-1297 hsa-miR-223 hsa-miR-374c hsa-miR-124
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat SEPT10

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEPT10

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SEP10_HUMAN, Q9P0V9: Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Note=Using a GFP-fusion protein,
    detected in the nucleus (PubMed:12711328)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton2
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031105septin complex IEA--

    SEPT10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SEPT10
    Interactions:

        Search GeneGlobe Interaction Network for SEPT10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for SEPT10 (Q9P0V92, 3 ENSP000003808244) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SEPT2Q150193, ENSP000003531574I2D: score=5 STRING: ENSP00000353157
    SEPT7Q161813, ENSP000003819924I2D: score=2 STRING: ENSP00000381992
    SEPT4O432363I2D: score=1 
    SYVN1Q86TM63I2D: score=1 
    ZBTB16Q055163I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle IEA--
    GO:0051301cell division IEA--

    SEPT10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SEPT10 (SEP10)

    1 HMDB Compound for SEPT10    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SEPT10 gene (2 alternative transcripts): 
    NM_144710.3  NM_178584.2  

    Unigene Cluster for SEPT10:

    Septin 10
    Hs.469615  [show with all ESTs]
    Unigene Representative Sequence: AB208875
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000356688(uc002tev.1 uc010ywu.1 uc002tey.3) ENST00000397712(uc010fjo.3 uc002tew.3 uc002tex.3 uc010ywv.2)
    ENST00000397714 ENST00000437928 ENST00000415095 ENST00000468616 ENST00000483047(uc002tez.1)
    ENST00000486678 ENST00000425498 ENST00000493445 ENST00000423520 ENST00000461295
    ENST00000411469 ENST00000442746 ENST00000334001 ENST00000545389
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SEPT10 (see all 28):
    hsa-miR-3910 hsa-miR-875-3p hsa-miR-4328 hsa-miR-4251 hsa-miR-1297 hsa-miR-223 hsa-miR-374c hsa-miR-124
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SEPT10
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    Primer
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    OriGene qPCR primer pairs and template standards for SEPT10
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SEPT10
      QuantiTect SYBR Green Assays in human, mouse, rat SEPT10
      QuantiFast Probe-based Assays in human, mouse, rat SEPT10

    Additional mRNA sequence: 

    AB208875.1 AF146760.1 AF316880.1 AK021681.1 AK022682.1 AK092033.1 AK125706.1 AK292038.1 
    AK294427.1 AK295560.1 AL049934.1 AL353938.1 BC020502.1 BC050345.1 NR_047585.1 

    11 DOTS entries:

    DT.80100472  DT.92030851  DT.95108491  DT.92458088  DT.99981848  DT.100737584  DT.121002171  DT.121002173 
    DT.92458093  DT.121473586  DT.92458073 

    Selected AceView cDNA sequences (see all 220):

    NM_144710 BG741340 BQ004232 AI342192 BQ574423 CB045753 BQ894369 BQ051149 
    BM467784 BM452966 AV682835 BC050345 BP365982 AV646068 AI206788 AI813851 
    AI735104 BM988805 AL353938 AW472997 AA778483 AI583048 BX494629 BE302006 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SEPT10 (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b
    SP1:                    -                                                                                                                           
    SP2:                                                                                                                                                
    SP3:                                -     -     -     -     -                                                                                       
    SP4:                                                                                                                                                
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for SEPT10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SEPT10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTGTATCAC
    SEPT10 Expression
    About this image


    SEPT10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
    SEPT10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SEPT10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.469615

    UniProtKB/Swiss-Prot: SEP10_HUMAN, Q9P0V9
    Tissue specificity: Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver
    and lung, as well as various tumor cell lines

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    QuantiFast Probe-based Assays in human, mouse, rat SEPT10
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SEPT10 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sept101 , 5 septin 101, 5 85.81(n)1
    85.89(a)1
      10 (29.48 cM)5
    1030801  NM_001024910.31  NP_001020081.21 
     591641135 
    chicken
    (Gallus gallus)
    Aves SEPT101 septin 10 75.13(n)
    75.13(a)
      418732  XM_004938526.1  XP_004938583.1 
    lizard
    (Anolis carolinensis)
    Reptilia SEPT106
    septin 10
    72(a)
    1 ↔ 1
    3(106895687-106922147)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.76042 Xenopus laevis transcribed sequence with moderate similarity more 77.03(n)    CA985775.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sept101 septin 10 72.33(n)
    79.67(a)
      550129  NM_001017557.1  NP_001017557.1 


    ENSEMBL Gene Tree for SEPT10 (if available)
    TreeFam Gene Tree for SEPT10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SEPT10 gene
    SEPT32  SEPT92  SEPT142  SEPT42  SEPT12  SEPT122  SEPT72  ENSG000002704662  
    SEPT62  SEPT112  SEPT22  SEPT82  SEPT52  
    18 SIMAP similar genes for SEPT10 using alignment to 13 protein entries:     SEP10_HUMAN (see all proteins):
    DKFZp564M1416    DKFZp547B243    SEPT11    SEPT6    SEPT8    SEPT14
    SEPT9    MAFK    SEPT3    SEPT7    SEPT2    SEPT5
    DKFZp686F17268    Nbla02942    SEPT4    SEPT1    SEPT12    DKFZp586I031

    SEPT10 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SEPT10
    PGOHUM00000249350


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SEPT10 (see all 1359)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs558803281,2
    C--103795681(+) CACAC-/AC/AC 
    ACACACAC
    TCACT
    3 -- int11NA 2
    rs1460656711,2
    --110299881(+) CATTGC/TGGCTG 3 -- ds50010--------
    rs1124809711,2
    C,F--110299898(+) GAGTGG/AGGCTT 3 -- ds50011Minor allele frequency- A:0.50NA 2
    rs613544801,2
    C--110299902(+) GAGGCT/CTTCTC 3 -- ds50014Minor allele frequency- C:0.11WA NA EA 360
    rs1143429971,2
    F--110299914(+) CAGCAG/ATCATC 3 -- ds50011Minor allele frequency- A:0.04WA 118
    rs1120937501,2
    C--110299925(+) AGCAGT/GACAAA 3 -- ds50012Minor allele frequency- G:0.05CSA WA 120
    rs1931186691,2
    C--110299935(+) AACGAC/TCGCCC 3 -- ds50010--------
    rs1847663671,2
    --110299979(+) ATTACA/GTTCTT 3 -- ds50010--------
    rs791980341,2
    C,F--110300018(+) CCATTC/ACAACA 3 -- ds50011Minor allele frequency- A:0.12EA 120
    rs1891019211,2
    --110300120(+) ACTCCC/TGCAGT 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for SEPT10 (110300376 - 110371783 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SEPT10:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2657195CNV Deletion23128226
    nsv2874CNV Loss18451855
    nsv874777CNV Gain21882294
    nsv829617CNV Gain20364138
    nsv510884CNV Complex20534489

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611737    OMIM disorders: --

    3 diseases for SEPT10:    
    About MalaCards
    b-cell chronic lymphocytic leukemia    chronic lymphocytic leukemia    leukemia


    SEPT10 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SEPT10

    Export disorders for SEPT10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SEPT10 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with SEPT10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional characterization of human septin 10, a novel member of septin family cloned from dendritic cells. (PubMed id 12711328)1, 2, 3, 9 Sui L.... Cao X. (Biochem. Biophys. Res. Commun. 2003)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Are surrogates of IGHV gene mutational status useful in B-cell chronic lymphocytic leukemia? The example of Septin-10. (PubMed id 17657217)1, 9 Benedetti D....Gattei V. (Leukemia 2008)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen. (PubMed id 22320903)1 Xu M....Kuroda M. (Cancer Sci. 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 151011 HGNC: 14349 AceView: SEPT10 Ensembl:ENSG00000186522 euGenes: HUgn151011
    ECgene: SEPT10 H-InvDB: SEPT10

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SEPT10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SEPT10 gene:
    Search GeneIP for patents involving SEPT10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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