Aliases for SEPT1 Gene
External Ids for SEPT1 Gene
Previous HGNC Symbols for SEPT1 Gene
Previous GeneCards Identifiers for SEPT1 Gene
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]
GeneCards Summary for SEPT1 Gene
SEPT1 (Septin 1) is a Protein Coding gene. Among its related pathways are Aurora B signaling and Bacterial invasion of epithelial cells. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is SEPT4.
UniProtKB/Swiss-Prot for SEPT1 Gene
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).