Aliases for SEPHS2 Gene
External Ids for SEPHS2 Gene
Previous GeneCards Identifiers for SEPHS2 Gene
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. Genes encoding selenocysteine contain a stem-loop secondary structure in their 3' UTR called a selenocysteine insertion sequence (SECIS) element. The protein encoded by this gene contains a selenocysteine residue in its predicted active site. There is a pseudogene for this gene on chromosome 5. [provided by RefSeq, Aug 2013]
GeneCards Summary for SEPHS2 Gene
SEPHS2 (Selenophosphate Synthetase 2) is a Protein Coding gene. Among its related pathways are Selenium Metabolism and Selenoproteins and Metabolism. GO annotations related to this gene include selenide, water dikinase activity. An important paralog of this gene is SEPHS1.
UniProtKB/Swiss-Prot for SEPHS2 Gene
Synthesizes selenophosphate from selenide and ATP.