SENP8 Gene
protein-coding GIFtS: 52
GCID: GC15P072410
|
|
SUMO/sentrin specific peptidase family member 8(Previous names: protease, cysteine, 2 (NEDD8 specific), SUMO/sentrin specific...) (Previous symbol: PRSC2)
| |
Aliases for SENP8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| SUMO/Sentrin Specific Peptidase Family Member 81 2 | | Deneddylase 12 | | DEN11 2 3 | | Deneddylase-13 | | NEDP11 2 3 | | NEDD8 Specific-Protease Cysteine 22 | | PRSC21 2 3 | | Sentrin-Specific Protease 82 | | Protease, Cysteine 22 3 | | SUMO Sentrin Specific Protease Family Member 82 | | NEDD8-Specific Protease 12 3 | | Deneddylase-13 | | HsT175121 | | EC 3.4.22.683 | | Protease, Cysteine, 2 (NEDD8 Specific)1 | | Sentrin/SUMO-Specific Protease SENP83 | | SUMO/Sentrin Specific Protease Family Member 81 | | |
Export aliases for SENP8 gene to outside databasesPrevious GC identifers: GC15P068212 GC15P065515 GC15P070126 GC15P070197 GC15P049236 |
Summaries for SENP8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SENP8: This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein isinvolved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expresseddevelopmentally downregulated 8. Alternate splicing results in multiple transcript variants.(provided by RefSeq, Oct2009) UniProtKB/Swiss-Prot: SENP8_HUMAN, Q96LD8Function: Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to itsmature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53 Gene Wiki entry for SENP8
|
Genomic Views for SENP8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SENP8 gene promoter: Sp1 SREBP-1c HNF-1A SREBP-1b CREB SREBP-1a deltaCREB HNF-1 MRF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for SENP8
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SENP8 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q23 Ensembl cytogenetic band: 15q23 HGNC cytogenetic band: 15q22.33SENP8 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P072410: view genomic region
(about GC identifiers)
Start:
|
72,406,599 bp from pter |
End:
|
72,433,311 bp from pter |
Size:
|
26,713 bases |
Orientation:
|
plus strand |
|
Proteins for SENP8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SENP8_HUMAN, Q96LD8 (See
protein sequence)Recommended Name: Sentrin-specific protease 8 Size: 212 amino acids; 24107 Da
3 PDB 3D structures from and Proteopedia for SENP8:1XT9 (3D)
  2BKQ (3D)
  2BKR (3D)
 
Secondary accessions: Q96QA4Explore the universe of human proteins at neXtProt for SENP8: NX_Q96LD8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96LD8 SENP8 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (5 alternative transcripts):
NP_001159812.1 NP_001165580.1 NP_001165581.1 NP_001165582.1 NP_660205.3 ENSEMBL proteins: ENSP00000446057 ENSP00000457208 ENSP00000456567 ENSP00000340505 ENSP00000457215 ENSP00000441753 ENSP00000439415 Human Recombinant Protein Products for SENP8:
SENP8 Antibody Products: Assay Products for SENP8: |
Protein
Domains / Families for SENP8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SENP8 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96LD8ProtoNet protein and cluster: Q96LD8 UniProtKB/Swiss-Prot: SENP8_HUMAN, Q96LD8Similarity: Belongs to the peptidase C48 family |
Function for SENP8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: SENP8_HUMAN, Q96LD8Function: Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to itsmature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53Catalytic activity: Hydrolysis of the alpha-linked peptide bond in the sequence Gly-Gly- -Ala-Thr-Tyr at the C-terminalend of the small ubiquitin-like modifier (SUMO) propeptide, Smt3, leading to the mature form of the protein. A secondreaction involves the cleavage of an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO andthe lysine epsilon-amino group of the target proteinBiophysicochemical properties: Kinetic parameters: KM=51 nM for Nedd8-AMC; Note=KM for Ub-AMC exceeds 5uM; Enzyme Number (IUBMB): EC 3.4.22.681
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008234 | cysteine-type peptidase activity |
IEA | -- |
SENP8 for ontologies About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SENP8 (see all 11) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SENP8 (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): SENP8 (NM_145204) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SENP8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SENP8  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SENP8 |
|
Pathways & Interactions for SENP8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SENP8
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
 5 Interacting proteins for SENP8 (Q96LD82, 3 ENSP000003405054) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006508 | proteolysis |
IEA | -- |
SENP8 for ontologies About GeneDecksing
|
Drugs & Compounds for SENP8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SENP8 Search CenterWatch for drugs/clinical trials and news about SENP8 
|
Transcripts for SENP8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SENP8 gene (5 alternative transcripts): NM_001166340.1 NM_001172109.1 NM_001172110.1 NM_001172111.1 NM_145204.3 Unigene Cluster for SENP8: SUMO/sentrin specific peptidase family member 8 Hs.513002 [show with all ESTs]Unigene Representative Sequence: NM_0011721097 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000542035(uc021spq.1) ENST00000567794 ENST00000564863 ENST00000340912 ENST00000564082 ENST00000544411(uc021spr.1 uc021sps.1) ENST00000544171(uc021spt.1 uc002atp.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SENP8 (see all 11) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SENP8 (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): SENP8 (NM_145204) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SENP8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SENP8  |
Additional cDNA sequence: AF308450.1 AK097557.1 AK292298.1 AY008293.1 BC031411.1 5 DOTS entries: DT.95261419 DT.97799296 DT.102821750 DT.121077461 DT.121077504 15 AceView cDNA sequences: BP370384 BC031411 NM_145204 CD245518 CR595304 AK097557 BI758706 BP376639 AL542781 BG699423 BX390779 CD689529 AL569616 BI548939 BI769620 GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for SENP8 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | |
| SP1: | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SENP8
|
Expression for SENP8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SENP8 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CACAGGCTTT
 About this image See SENP8 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SENP8
SOURCE GeneReport for Unigene cluster: Hs.513002
UniProtKB/Swiss-Prot: SENP8_HUMAN, Q96LD8Tissue specificity: Broadly expressed, with highest levels in kidney and pancreas SABiosciences Custom PCR Arrays for SENP8
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SENP8 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SENP8 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SENP8 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SENP8 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SENP8 |
Orthologs for SENP8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SENP8 gene from 9/25 species (see all 25) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Senp81 , 5 |
SUMO/sentrin specific peptidase 81, 5 |
90.25(n)1 92.45(a)1 |
  |
9 (32.11 cM)5 715991 NM_001172071.11 NP_001165542.11 597342595 |
chicken (Gallus gallus) |
Aves |
SENP81 |
SUMO/sentrin specific peptidase family member 8 |
75(n) 76.42(a) |
  |
415322 XM_413710.3 XP_413710.1 |
lizard (Anolis carolinensis) |
Reptilia |
SENP86 |
-- |
71(a) |
1 ↔ 1 |
GL343479.1(396865-397642) |
tropical clawed frog (Xenopus tropicalis) |
Amphibia |
1420032952 |
-- |
77.23(n) |
  |
142003295 |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.195982 |
Transcribed sequence with weak similarity to protein more |
77.23(n) |
  |
BI868113.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Den11 |
Deneddylase 1 |
48.47(n) 37.2(a) |
  |
36339 NM_001169655.1 NP_001163126.1 |
worm (Caenorhabditis elegans) |
Secernentea |
ulp-36 |
Ubiquitin-Like Protease family member (ulp-3) |
26(a) |
1 ↔ 1 |
IV(1963191-1964717) |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT5G601901 |
NEDD8-specific protease 1 |
46.05(n) 37.57(a) |
  |
836141 NM_125412.3 NP_200827.1 |
rice (Oryza sativa) |
Liliopsida |
---- |
ulp1 protease family protein, putative, expressedOsWRKY57v2 - Superfamily of TFs having WRKY and zi... |
26(a)14(a) |
many → 1many → 1 |
11(106194-107210) 12(99799-103008) |
ENSEMBL Gene Tree for SENP8 (if available) TreeFam Gene Tree for SENP8 (if available)  |
Paralogs for SENP8 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for SENP8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 15 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SENP8 (72406599 - 72433311 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for SENP8 2 CNVs: 87732 87731  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SENP8 |
|
Disorders
/ Diseases for SENP8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SENP8 for disorders About GeneDecksing
OMIM gene information: 608659
OMIM disorders: --
8 diseases for SENP8: About MalaCardsjapanese encephalitis yellow fever encephalitis dengue disease prostate carcinoma breast cancer prostatitis carcinoma Export disorders for SENP8 gene to outside databases
|
Publications for SENP8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SENP8 gene, integrated from 9 sources (see all 32): (articles sorted by number of sources associating them with SENP8) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification and characterization of DEN1, a deneddylase of the ULP family. (PubMed id 12759362)1, 2, 3, 9 Gan-Erdene T....Wilkinson K.D. (2003)
- NEDP1, a highly conserved cysteine protease that deneddylates cullins. (PubMed id 12730221)1, 2, 3 Mendoza H.M....Hay R.T. (2003)
- DEN1 is a dual function protease capable of processing the C-terminus of Nedd8 and deconjugating hyper-neddylated CUL1. (PubMed id 12759363)1, 2, 9 Wu K.... Pan Z.-Q. (2003)
- Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1. (PubMed id 15567417)1, 2, 9 Reverter D.... Lima C.D. (2005)
- Structural basis of NEDD8 ubiquitin discrimination by the deneddylating enzyme NEDP1. (PubMed id 15775960)1, 2 Shen L.-N.... Hay R.T. (2005)
- Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity. (PubMed id 15242646)1, 2 Xirodimas D.P.... Lane D.P. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity. (PubMed id 19328766)1, 9 Engels I.H....Brinker A. (2009)
- hCINAP is a novel regulator of ribosomal protein-HDM2- p53 pathway by controlling NEDDylation of ribosomal protein S14. (PubMed id 23246961)1 Zhang J....Zheng X. (2012)
- A microarray of ubiquitylated proteins for profiling d eubiquitylase activity reveals the critical roles of both chain and substrate. (PubMed id 22626734)1 Loch C.M. and Strickler J.E. (2012)
|
External Searches for SENP8 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SENP8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SENP8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SENP8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SENP8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SENP8 gene: Search GeneIP for patents involving SENP8
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SENP8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SENP8 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SENP8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SENP8 | | OriGene Protein Over-expression Lysate for SENP8 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SENP8 | | OriGene 3'-UTR Clone for SENP8 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SENP8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SENP8 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for SENP8 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SENP8 | | OriGene Custom Protein Services for SENP8 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SENP8 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SENP8 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SENP8 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SENP8 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SENP8 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SENP8 |
| |
 |  |  |  | |
| | | Search Tocris compounds for SENP8 |
| |  |  |  |  | | | | | Recombinant Protein for SENP8 |
|
 |
 |
 |
 | | SENP8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SENP8 |
|  |  |  |  | | | ThermoFisher Antibodies for SENP8 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SENP8 |
| |  | |
|
|
|