Aliases for SENP8 Gene
External Ids for SENP8 Gene
Previous HGNC Symbols for SENP8 Gene
Previous GeneCards Identifiers for SENP8 Gene
This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
GeneCards Summary for SENP8 Gene
SENP8 (SUMO/Sentrin Peptidase Family Member, NEDD8 Specific) is a Protein Coding gene. Diseases associated with SENP8 include Exanthem. Among its related pathways are Metabolism of proteins and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include cysteine-type peptidase activity and NEDD8-specific protease activity.
UniProtKB/Swiss-Prot for SENP8 Gene
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.