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Aliases for SENP3-EIF4A1 Gene

Subcategory (RNA class) for SENP3-EIF4A1 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for SENP3-EIF4A1 Gene

  • SENP3-EIF4A1 Readthrough (NMD Candidate) 2 3 5

External Ids for SENP3-EIF4A1 Gene

Previous GeneCards Identifiers for SENP3-EIF4A1 Gene

  • GC17U901629
  • GC17P007469
  • GC17P007568
  • GC17P007570
  • GC17P007617
  • GC17P007655
  • GC17P007681

Summaries for SENP3-EIF4A1 Gene

Entrez Gene Summary for SENP3-EIF4A1 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring SUMO1/sentrin/SMT3 specific peptidase 3 (SENP3) and eukaryotic translation initiation factor 4A1 (EIF4A1) genes on chromosome 17. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Mar 2011]

GeneCards Summary for SENP3-EIF4A1 Gene

SENP3-EIF4A1 (SENP3-EIF4A1 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. Gene Ontology (GO) annotations related to this gene include cysteine-type peptidase activity. An important paralog of this gene is SENP3.

Additional gene information for SENP3-EIF4A1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SENP3-EIF4A1 Gene

Genomics for SENP3-EIF4A1 Gene

GeneHancer (GH) Regulatory Elements for SENP3-EIF4A1 Gene

Promoters and enhancers for SENP3-EIF4A1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I007556 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 0.8 -2.2 -2201 7.1 HDGF MLX ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF213 ZNF143 DEK TNFSF13 ENSG00000276384 GC17P007747 SENP3 SAT2 CHRNB1 TNFSF12 SNORA48 SENP3-EIF4A1 TNFSF12-TNFSF13
GH17I007571 Promoter/Enhancer 2.6 EPDnew Ensembl ENCODE dbSUPER 0.4 +16.2 16167 14.2 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 SNORD10 EIF4A1 GC17P007735 GC17P007737 GC17P007739 GC17P007742 PIR46508 SNORA67 CD68 MPDU1
GH17I007568 Enhancer 0.2 dbSUPER 0.4 +6.6 6646 0.2 GC17P007743 SENP3 SENP3-EIF4A1
GH17I007567 Enhancer 0.2 dbSUPER 0.4 +6.0 5975 0.8 ATP1B2 GC17P007743 SENP3 SENP3-EIF4A1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SENP3-EIF4A1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SENP3-EIF4A1 Gene

Genomic Locations for SENP3-EIF4A1 Gene
chr17:7,561,992-7,579,006
(GRCh38/hg38)
Size:
17,015 bases
Orientation:
Plus strand
chr17:7,465,309-7,482,324
(GRCh37/hg19)

Genomic View for SENP3-EIF4A1 Gene

Genes around SENP3-EIF4A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SENP3-EIF4A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SENP3-EIF4A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SENP3-EIF4A1 Gene

Proteins for SENP3-EIF4A1 Gene

  • Protein details for SENP3-EIF4A1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087X0R7
    Recommended name:
    SENP3-EIF4A1 readthrough (NMD candidate)
    Protein Accession:
    A0A087X0R7

    Protein attributes for SENP3-EIF4A1 Gene

    Size:
    540 amino acids
    Molecular mass:
    61278 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SENP3-EIF4A1 Gene

Post-translational modifications for SENP3-EIF4A1 Gene

No Post-translational modifications

Other Protein References for SENP3-EIF4A1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for SENP3-EIF4A1 Gene

Domains & Families for SENP3-EIF4A1 Gene

Protein Domains for SENP3-EIF4A1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SENP3-EIF4A1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SENP3-EIF4A1 Gene

Function for SENP3-EIF4A1 Gene

Phenotypes From GWAS Catalog for SENP3-EIF4A1 Gene

Gene Ontology (GO) - Molecular Function for SENP3-EIF4A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008234 cysteine-type peptidase activity IEA --
genes like me logo Genes that share ontologies with SENP3-EIF4A1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SENP3-EIF4A1 Gene

Localization for SENP3-EIF4A1 Gene

Gene Ontology (GO) - Cellular Components for SENP3-EIF4A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with SENP3-EIF4A1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SENP3-EIF4A1 Gene

Pathways & Interactions for SENP3-EIF4A1 Gene

SuperPathways for SENP3-EIF4A1 Gene

No Data Available

Interacting Proteins for SENP3-EIF4A1 Gene

Gene Ontology (GO) - Biological Process for SENP3-EIF4A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0016926 protein desumoylation IBA --
genes like me logo Genes that share ontologies with SENP3-EIF4A1: view

No data available for Pathways by source and SIGNOR curated interactions for SENP3-EIF4A1 Gene

Drugs & Compounds for SENP3-EIF4A1 Gene

No Compound Related Data Available

Transcripts for SENP3-EIF4A1 Gene

mRNA/cDNA for SENP3-EIF4A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SENP3-EIF4A1 Gene

No ASD Table

Relevant External Links for SENP3-EIF4A1 Gene

GeneLoc Exon Structure for
SENP3-EIF4A1
ECgene alternative splicing isoforms for
SENP3-EIF4A1

Expression for SENP3-EIF4A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SENP3-EIF4A1 Gene

genes like me logo Genes that share expression patterns with SENP3-EIF4A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SENP3-EIF4A1 Gene

Orthologs for SENP3-EIF4A1 Gene

Evolution for SENP3-EIF4A1 Gene

ENSEMBL:
Gene Tree for SENP3-EIF4A1 (if available)
TreeFam:
Gene Tree for SENP3-EIF4A1 (if available)

No data available for Orthologs for SENP3-EIF4A1 Gene

Paralogs for SENP3-EIF4A1 Gene

Paralogs for SENP3-EIF4A1 Gene

genes like me logo Genes that share paralogs with SENP3-EIF4A1: view

Variants for SENP3-EIF4A1 Gene

Sequence variations from dbSNP and Humsavar for SENP3-EIF4A1 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000205759 -- 7,578,715(+) A/C non_coding_transcript_variant
rs1000276181 -- 7,568,423(+) CT/ intron_variant
rs1000775375 -- 7,561,826(+) G/A upstream_transcript_variant
rs1000840931 -- 7,562,723(+) G/A intron_variant
rs1000879861 -- 7,567,083(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for SENP3-EIF4A1 Gene

Variant ID Type Subtype PubMed ID
esv2422288 CNV deletion 17116639
nsv457659 CNV loss 19166990
nsv574322 CNV loss 21841781
nsv960400 CNV duplication 23825009
nsv960401 CNV duplication 23825009

Additional Variant Information for SENP3-EIF4A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SENP3-EIF4A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SENP3-EIF4A1 Gene

Disorders for SENP3-EIF4A1 Gene

Additional Disease Information for SENP3-EIF4A1

No disorders were found for SENP3-EIF4A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SENP3-EIF4A1 Gene

Publications for SENP3-EIF4A1 Gene

  1. Genome-wide scan identifies variant in TNFSF13 associated with serum IgM in a healthy Chinese male population. (PMID: 23118916) Yang M … Mo Z (PloS one 2012) 3 58
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  4. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3

Products for SENP3-EIF4A1 Gene

Sources for SENP3-EIF4A1 Gene

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