SENP2 Gene
protein-coding GIFtS: 59
GCID: GC03P185301
|
|
SUMO1/sentrin/SMT3 specific peptidase 2(Previous name: SUMO1/sentrin/SMT3 specific protease 2 )
| |
Aliases
for SENP2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SUMO1/Sentrin/SMT3 Specific Peptidase 21 2 | | EC 3.4.22.683 8 | | AXAM21 2 5 | | DKFZp762A23161 | | SMT3IP21 2 5 | | Sentrin-Specific Protease 22 | | KIAA13311 3 5 | | Axam23 | | SUMO1/Sentrin/SMT3 Specific Protease 21 2 | | Smt3ip23 | | Sentrin/SUMO-Specific Protease SENP22 3 | | EC 3.4.228 | | SMT3-Specific Isopeptidase 22 3 | | |
Export aliases for SENP2 gene to outside databasesPrevious GC identifers: GC03P182095 GC03M186470 GC03P186706 GC03P186624 GC03P186786 GC03P182713 |
Summaries
for SENP2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SENP2:
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze thedeconjugation of SUMO1-containing species.(supplied by OMIM, Apr 2004)
UniProtKB/Swiss-Prot: SENP2_HUMAN, Q9HC62Function: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulateCTNNB1 levels and thereby modulate the Wnt pathway (By similarity)
Gene Wiki entry for SENP2
|
Genomic Views
for SENP2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SENP2 gene promoter:
AhR RFX1 GATA-3 Tal-1beta Arnt GATA-2 GATA-1 Evi-1 Pax-3 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SENP2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SENP2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q27.2 Ensembl cytogenetic band: 3q27.2 HGNC cytogenetic band: 3q28SENP2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P185301: view genomic region
(about GC identifiers)
Start:
|
185,300,284 bp from pter |
End:
|
185,351,339 bp from pter |
Size:
|
51,056 bases |
Orientation:
|
plus strand |
|
Proteins
for SENP2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SENP2_HUMAN, Q9HC62 (See
protein sequence)Recommended Name: Sentrin-specific protease 2 Size: 589 amino acids; 67855 Da
Subunit: Binds to SUMO2 and SUMO3 (By similarity). Interacts with the C-terminal domain of NUP153 via its N-terminus
Subcellular location: Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.Cytoplasm. Note=Shuttles between cytoplasm and nucleus
6 PDB 3D structures from  and Proteopedia  for SENP2:1TGZ (3D)
1TH0 (3D)
2IO0 (3D)
2IO1 (3D)
2IO2 (3D)
2IO3 (3D)
Secondary accessions: Q8IW97 Q96SR2 Q9P2L5Explore the universe of human proteins at neXtProt for SENP2: NX_Q9HC62
Post-translational modifications:
Polyubiquitinated; which leads to proteasomal degradation1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HC62
4/6 DME Specific Peptides for SENP2 (Q9HC62) (see all 6)
SENP2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_067640.2
ENSEMBL proteins: ENSP00000399156 ENSP00000296257 ENSP00000393197 ENSP00000388893 ENSP00000390229 ENSP00000408114 ENSP00000399201 ENSP00000439653 ENSP00000394562
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SENP2 for ontologies About GeneDecksing
SENP2 Antibody Products:
Assay Products for SENP2: |
Protein
Domains /
Families
for SENP2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SENP2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9HC62ProtoNet protein and cluster: Q9HC62 1 Blocks protein family: IPB003653 SUMO/Sentrin/Ubl1 specific protease
UniProtKB/Swiss-Prot: SENP2_HUMAN, Q9HC62Domain: The N-terminus is necessary and sufficient for nuclear envelope targetingSimilarity: Belongs to the peptidase C48 family |
Function
for SENP2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SENP2_HUMAN, Q9HC62Function: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulateCTNNB1 levels and thereby modulate the Wnt pathway (By similarity)Catalytic activity: Hydrolysis of the alpha-linked peptide bond in the sequence Gly-Gly- -Ala-Thr-Tyr at the C-terminalend of the small ubiquitin-like modifier (SUMO) propeptide, Smt3, leading to the mature form of the protein. A secondreaction involves the cleavage of an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO andthe lysine epsilon-amino group of the target proteinEnzyme Numbers (IUBMB): EC 3.4.22.681 2 EC 3.4.222
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SENP2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SENP2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SENP2 (NM_021627) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SENP2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SENP2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SENP2 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SENP2 for ontologies About GeneDecksing
Animal Models:
4 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Senp2):
SENP2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SENP2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Wnt Signaling Pathway | | | 2 | RNA transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SENP2
2 
Kegg Pathways (Kegg details for SENP2):
SENP2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SENP2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/34 Interacting proteins for SENP2 (Q9HC621, 2, 3 ENSP000002962574) via UniProtKB, MINT, STRING, and/or I2D (see all 34)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
SENP2 for ontologies About GeneDecksing
|
Drugs & Compounds
for SENP2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SENP2
Search CenterWatch for drugs/clinical trials and news about SENP2
|
Transcripts
for SENP2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SENP2 gene: NM_021627.2 Unigene Cluster for SENP2: SUMO1/sentrin/SMT3 specific peptidase 2 Hs.401388 [show with all ESTs]Unigene Representative Sequence: NM_02162715 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000430355 ENST00000465201 ENST00000296257(uc011brv.2 uc003fpn.3 uc011brw.2)
ENST00000453532 ENST00000413407 ENST00000439684 ENST00000458551 ENST00000473760
ENST00000459883 ENST00000478001 ENST00000476011 ENST00000444509 ENST00000483005
ENST00000545472 ENST00000427465
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SENP2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SENP2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SENP2 (NM_021627) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SENP2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SENP2 |
Additional cDNA sequence: AF151697.2 AK027599.1 AK074357.1 AK296744.1 AK296772.1 AK298628.1 AK304402.1 AL834380.1 BC018020.1 BC040609.1 17 DOTS entries: DT.446306 DT.100784573 DT.100784569 DT.97843847 DT.97785493 DT.120856151 DT.86847609 DT.92453535 DT.100681740 DT.100727021 DT.102831613 DT.120856132 DT.120856134 DT.120856137 DT.120856156 DT.97821649 DT.95235804 24/192 AceView cDNA sequences (see all 192): BQ232728 BP360516 CF886833 Z38481 BM759473 AI417493 AA705377 AI249722 AI493144 BM723152 AI075943 AI089661 BG288026 AA974418 AI337327 CB242144 CA315010 AA588335 CF272268 AI651270 AL561253 BU182253 AU280652 AA554558
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SENP2 (see all 11) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | - | | | | | | | | - | | |
| SP2: | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14 | ^ | 15 | ^ | 16 | ^ | 17 |
|---|
|
| SP1: | | | | | | | | | |
| SP2: | | | | | | | | | |
| SP3: | | | | | | | | | |
| SP4: | | | | | | | | | |
| SP5: | | | | | | | | |
ECgene alternative splicing isoforms for SENP2
|
Expression
for SENP2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SENP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SENP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SENP2
SOURCE GeneReport for Unigene cluster: Hs.401388
SABiosciences Custom PCR Arrays for SENP2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SENP2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SENP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SENP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SENP2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SENP2 |
Orthologs
for SENP2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SENP2 gene from 7/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SENP21 |
SUMO1/sentrin/SMT3 specific peptidase 2 |
57.83(n)
50.84(a) |
|
424864 XM_422676.3 XP_422676.3 |
lizard
(Anolis carolinensis) |
Reptilia |
SENP26 |
-- |
44(a) |
1 ↔ 1 |
3(34416251-34428558) |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb78c012 |
Transcribed sequence with weak similarity to protein refNP_067640.1 (H.sapiens) sentrin-specific protease [Homo sapiens] less |
74.85(n) |
|
AL728060.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Ulp13 |
protein deubiquitination ubiquitin-specific
protease less |
43(a)
(best of 2) |
|
18B1 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
T10F2.33 |
-- |
34(a) |
|
III(5237838-5241523) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ULP1B6ESD46(see all 3) |
ubiquitin-like-specific protease ESD4(see all 3) |
28(a)22(a)(see all 3) |
many ↔ manymany ↔ many(see all 3) |
4(281313-283129) 4(9012645-9016116) |
rice
(Oryza sativa) |
Liliopsida |
----(see all 3) |
ulp1 protease family protein, putative, expressed(see all 3) |
26(a)26(a)(see all 3) |
many ↔ manymany ↔ many(see all 3) |
3(16887750-16891075) 3(12822303-12826996) |
ENSEMBL Gene Tree for SENP2 (if available)
TreeFam Gene Tree for SENP2 (if available) |
Paralogs
for SENP2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SENP2 gene
- SENP32 SENP12 SENP52
2 SIMAP similar genes for SENP2 using alignment to 9 protein entries: SENP2_HUMAN (see all proteins):SENP1 SENP5
SENP2 for paralogs About GeneDecksing
|
Genomic Variants
for SENP2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SENP2 (185300284 - 185351339 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SENP2: -- | SABiosciences Cancer Mutation PCR Assays |
| 1 SABiosciences qBiomarker Copy Number PCR Array containing SENP2: |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SENP2 |
|
Disorders
/ Diseases
for SENP2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SENP2 for disorders About GeneDecksing
OMIM gene information: 608261
OMIM disorders: --
3  diseases for SENP2: About MalaCardsprostate cancer prostatitis malaria
Export disorders for SENP2 gene to outside databases
|
Publications
for SENP2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SENP2 gene, integrated from 9 sources (see all 42):
(articles sorted by number of sources associating them with SENP2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Association of the human SUMO-1 protease SENP2 with the nuclear pore. (PubMed id 11896061)1, 2, 3 Hang J. and Dasso M. (2002)
- Characterization of a novel mammalian SUMO-1/Smt3-spe cific isopeptidase, a homologue of rat axam, which is an axin-binding protein p romoting beta-catenin degradation. (PubMed id 11489887)1, 3, 9 Nishida T....Yasuda H. (2001)
- Nucleocytoplasmic shuttling modulates activity and ubiquitination- dependent turnover of SUMO-specific protease 2. (PubMed id 16738331)1, 2 Itahana Y.... Zhang Y. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex. (PubMed id 15296745)1, 2 Reverter D. and Lima C.D. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex. (PubMed id 12192048)1, 2 Zhang H.... Matunis M.J. (2002)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
- A microarray of ubiquitylated proteins for profiling d eubiquitylase activity reveals the critical roles of both chain and substrate. (PubMed id 22626734)1 Loch C.M. and Strickler J.E. (2012)
|
External Searches for SENP2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SENP2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SENP2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SENP2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SENP2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SENP2 gene:
Search GeneIP for patents involving SENP2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SENP2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SENP2 | | OriGene shRNA RFP for SENP2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SENP2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SENP2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SENP2 | | OriGene 3'-UTR Clone for SENP2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SENP2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SENP2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SENP2 | | OriGene Custom Protein Services for SENP2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SENP2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SENP2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SENP2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SENP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SENP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SENP2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SENP2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | SENP2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SENP2 |
|  |  |  | | | | ThermoFisher Antibody for SENP2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SENP2 |
|
|
|
|
