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Aliases for SENCR Gene

Subcategory (RNA class) for SENCR Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for SENCR Gene

  • Smooth Muscle And Endothelial Cell Enriched Migration/Differentiation-Associated LncRNA 2 3
  • Smooth Muscle And Endothelial Cell Enriched Migration/Differentiation-Associated Long Non-Coding RNA 2 3 5
  • FLI1 Antisense RNA 1 (Non-Protein Coding) 2 3
  • FLI1 Antisense RNA 1 2
  • FLI1-AS1 3
  • LncRNA9 3

External Ids for SENCR Gene

Previous HGNC Symbols for SENCR Gene

  • FLI1-AS1

Previous GeneCards Identifiers for SENCR Gene

  • GC11M128564

Summaries for SENCR Gene

GeneCards Summary for SENCR Gene

SENCR (Smooth Muscle And Endothelial Cell Enriched Migration/Differentiation-Associated LncRNA) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for SENCR Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SENCR Gene

Genomics for SENCR Gene

Regulatory Elements for SENCR Gene

Enhancers for SENCR Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H128723 1.7 FANTOM5 Ensembl ENCODE dbSUPER 12.7 -36.0 -36044 17 HDGF PKNOX1 TBL1XR1 RB1 SIN3A BMI1 BATF ATF7 ETV6 RUNX3 FLI1 SENCR LOC101929538 KCNJ1 ETS1 GC11P128789
GH11H128620 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.8 +70.1 70087 10 PKNOX1 RB1 RAD21 YY1 ZNF766 ZNF143 FOS RUNX3 IKZF2 ZNF654 FLI1 ETS1 SENCR LOC101929517 LOC105369568 GC11P128667
GH11H128288 1.8 FANTOM5 Ensembl ENCODE dbSUPER 10.5 +398.0 398010 18 HDGF PKNOX1 TBL1XR1 RB1 SIN3A BMI1 FEZF1 BATF RAD21 YY1 ETS1 FLI1 LOC101929517 SENCR GC11P128293 GC11M128298
GH11H128745 1 Ensembl ENCODE dbSUPER 12.4 -50.8 -50802 3 FOXA2 RFX1 POLR2A BMI1 SENCR FLI1 GC11P128789
GH11H128653 0.8 Ensembl ENCODE 12.5 +42.0 42019 1 MAFG CEBPG ATF7 NFE2 GABPA FLI1 LOC101929538 SENCR LOC101929517 GC11P128667 LOC105369568
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SENCR on UCSC Golden Path with GeneCards custom track

Promoters for SENCR Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000046906 1623 3601 SIN3A ZNF2 GLIS2 ZNF366 ZNF143 ATF7 ETV6 RUNX3 IKZF2 ZNF362

Genomic Location for SENCR Gene

Chromosome:
11
Start:
128,691,672 bp from pter
End:
128,696,023 bp from pter
Size:
4,352 bases
Orientation:
Minus strand

Genomic View for SENCR Gene

Genes around SENCR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SENCR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SENCR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SENCR Gene

Proteins for SENCR Gene

Post-translational modifications for SENCR Gene

No Post-translational modifications

No data available for DME Specific Peptides for SENCR Gene

Domains & Families for SENCR Gene

Gene Families for SENCR Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SENCR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SENCR Gene

Function for SENCR Gene

Phenotypes From GWAS Catalog for SENCR Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SENCR Gene

Localization for SENCR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SENCR Gene

Pathways & Interactions for SENCR Gene

SuperPathways for SENCR Gene

No Data Available

Interacting Proteins for SENCR Gene

Gene Ontology (GO) - Biological Process for SENCR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SENCR Gene

Drugs & Compounds for SENCR Gene

No Compound Related Data Available

Transcripts for SENCR Gene

mRNA/cDNA for SENCR Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SENCR Gene

No ASD Table

Relevant External Links for SENCR Gene

GeneLoc Exon Structure for
SENCR
ECgene alternative splicing isoforms for
SENCR

Expression for SENCR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SENCR Gene

mRNA differential expression in normal tissues according to GTEx for SENCR Gene

This gene is overexpressed in Whole Blood (x7.9) and Spleen (x6.8).

NURSA nuclear receptor signaling pathways regulating expression of SENCR Gene:

SENCR
genes like me logo Genes that share expression patterns with SENCR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SENCR Gene

Orthologs for SENCR Gene

Evolution for SENCR Gene

ENSEMBL:
Gene Tree for SENCR (if available)
TreeFam:
Gene Tree for SENCR (if available)

No data available for Orthologs for SENCR Gene

Paralogs for SENCR Gene

No data available for Paralogs for SENCR Gene

Variants for SENCR Gene

Sequence variations from dbSNP and Humsavar for SENCR Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000050060 -- 128,693,519(+) CCCCC(C/G/T)CTACC intron-variant, upstream-variant-2KB
rs1001533802 -- 128,694,043(+) TTAGC(C/T)GAAAA intron-variant, utr-variant-5-prime
rs1001669509 -- 128,696,002(+) TCTCC(A/G)CACTG intron-variant, nc-transcript-variant
rs1001803809 -- 128,695,660(+) ACTGA(C/T)TGTGA intron-variant
rs1001865939 -- 128,695,164(+) CAGCC(A/G)CCGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SENCR Gene

Variant ID Type Subtype PubMed ID
nsv1070495 CNV deletion 25765185
nsv826128 CNV gain 20364138
nsv952759 CNV duplication 24416366

Relevant External Links for SENCR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SENCR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SENCR Gene

Disorders for SENCR Gene

Relevant External Links for SENCR

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SENCR

No disorders were found for SENCR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SENCR Gene

Publications for SENCR Gene

  1. Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA. (PMID: 24578380) Bell RD … Miano JM (Arteriosclerosis, thrombosis, and vascular biology 2014) 2 3 60
  2. A Role for the Long Noncoding RNA SENCR in Commitment and Function of Endothelial Cells. (PMID: 26898221) Boulberdaa M … Baker AH (Molecular therapy : the journal of the American Society of Gene Therapy 2016) 3 60

Products for SENCR Gene

Sources for SENCR Gene

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