Aliases for SEMA7A Gene
Aliases for SEMA7A Gene
- Semaphorin 7A (John Milton Hagen Blood Group) 2 3
- Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) 2 3 5
- Sema Domain, Immunoglobulin Domain (Ig), And GPI Membrane Anchor, (Semaphorin) 7A (JMH Blood Group) 2 3
- John-Milton-Hargen Human Blood Group Ag 3 4
- JMH Blood Group Antigen 3 4
- Semaphorin-K1 3 4
- Semaphorin-L 3 4
- Sema K1 3 4
- Sema L 3 4
- CDw108 3 4
- SEMAL 3 4
- CD108 3 4
External Ids for SEMA7A Gene
- HGNC: 10741
- Entrez Gene: 8482
- Ensembl: ENSG00000138623
- OMIM: 607961
- UniProtKB: O75326
Previous HGNC Symbols for SEMA7A Gene
- SEMAL
Previous GeneCards Identifiers for SEMA7A Gene
- GC15M070720
- GC15M067816
- GC15M072278
- GC15M072418
- GC15M072489
- GC15M074701
- GC15M051497
Summaries for SEMA7A Gene
-
This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
GeneCards Summary for SEMA7A Gene
SEMA7A (Semaphorin 7A (John Milton Hagen Blood Group)) is a Protein Coding gene. Diseases associated with SEMA7A include Chromosome 15Q24 Deletion Syndrome and Hemoglobinuria. Among its related pathways are Axon guidance and Developmental Biology. GO annotations related to this gene include receptor activity and integrin binding. An important paralog of this gene is SEMA6C.
UniProtKB/Swiss-Prot for SEMA7A Gene
-
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SEMA7A Gene
Genomics for SEMA7A Gene
Regulatory Elements for SEMA7A Gene
Enhancers for SEMA7A Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around SEMA7A on UCSC Golden Path with GeneCards custom track
Promoters for SEMA7A Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around SEMA7A on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for SEMA7A Gene
- Chromosome:
- 15
- Start:
- 74,409,289 bp from pter
- End:
- 74,434,467 bp from pter
- Size:
- 25,179 bases
- Orientation:
- Minus strand
Genomic View for SEMA7A Gene
Genes around SEMA7A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q24.1 by Ensembl
- 15q22.3-q23 by Entrez Gene
- 15q22.3-q23 by HGNC
SEMA7A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SEMA7A Gene
Proteins for SEMA7A Gene
-
Protein details for SEMA7A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75326-SEM7A_HUMAN
- Recommended name:
- Semaphorin-7A
- Protein Accession:
- O75326
- B4DDP7
- F5H1S0
- Q1XE81
- Q1XE82
- Q1XE83
- Q1XE84
- Q3MIY5
Protein attributes for SEMA7A Gene
- Size:
- 666 amino acids
- Molecular mass:
- 74824 Da
- Quaternary structure:
-
- Interacts with ITGA1 and ITGB1 (Probable). Interacts with PLXNC1.
Protein Expression for SEMA7A Gene
Post-translational modifications for SEMA7A Gene
Other Protein References for SEMA7A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for SEMA7A (Semaphorin 7A)
- Novus Biologicals Antibodies for SEMA7A
-
Cloud-Clone Corp. Antibodies for SEMA7A
- Invitrogen Antibodies for SEMA7A
- antibodies-online Antibodies for SEMA7A: See all 79
- GeneTex SEMA7A antibody for SEMA7A
-
Santa Cruz Biotechnology (SCBT) Antibodies for SEMA7A
Protein Products
- R&D Systems Proteins and Enzymes for SEMA7A (Semaphorin 7A)
-
OriGene Purified Proteins for SEMA7A
- Search Origene for MassSpec and Protein Over-expression Lysates for SEMA7A
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-
Cloud-Clone Corp. Proteins for SEMA7A
- antibodies-online Proteins for SEMA7A: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Proteins for SEMA7A
No data available for DME Specific Peptides for SEMA7A Gene
Domains & Families for SEMA7A Gene
Gene Families for SEMA7A Gene
Protein Domains for SEMA7A Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for SEMA7A Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O75326UniProtKB/Swiss-Prot:
SEM7A_HUMAN :- Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
- Belongs to the semaphorin family.
- Domain:
-
- Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
- Contains 1 PSI domain.
- Contains 1 Sema domain.
- Family:
-
- Belongs to the semaphorin family.
Function for SEMA7A Gene
Molecular function for SEMA7A Gene
- GENATLAS Biochemistry:
- semaphorin 7A,74.8kDa,expressed in the placenta,spleen,thymus and gonadal tissues,ligand for the plexin C1,putative counterpart of the viral semaphorin VB
- UniProtKB/Swiss-Prot Function:
- Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated in UV-irradiated fibroblasts, but not in UV-irradiated keratinocytes.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0030215 | NOT semaphorin receptor binding | IBA | -- |
Phenotypes for SEMA7A Gene
- MGI mutant phenotypes for SEMA7A:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SEMA7A:
Animal Models for SEMA7A Gene
- MGI Knock Outs for SEMA7A:
-
- Sema7a tm1Alk
Animal Model Products
-
Taconic Biosciences Mouse Models for SEMA7A
-
ViGene Biosciences lentiviral particle packaged cDNA for SEMA7A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SEMA7A gene
- Search ViGene Biosciences for SEMA7A
CRISPR Products
-
OriGene CRISPR knockouts for SEMA7A
-
Santa Cruz Biotechnology (SCBT) CRISPR for SEMA7A
- GenScript: Design CRISPR guide RNA sequences for SEMA7A
miRNA for SEMA7A Gene
- miRTarBase miRNAs that target SEMA7A
-
- hsa-mir-615-3p (MIRT040303)
- hsa-mir-4267 (MIRT386120)
- hsa-mir-6762-5p (MIRT386137)
- hsa-mir-6845-5p (MIRT386141)
- hsa-mir-27a-3p (MIRT437947)
- hsa-mir-580-3p (MIRT492349)
- hsa-mir-4477a (MIRT492350)
- hsa-mir-3926 (MIRT492351)
- hsa-mir-6722-3p (MIRT492352)
- hsa-mir-1909-3p (MIRT492353)
- hsa-mir-6836-5p (MIRT492354)
- hsa-mir-6132 (MIRT492355)
- hsa-mir-6770-5p (MIRT492356)
- hsa-mir-1253 (MIRT492357)
- hsa-mir-4461 (MIRT492358)
- hsa-mir-126-5p (MIRT492359)
- hsa-mir-5197-3p (MIRT492360)
- hsa-mir-519c-3p (MIRT492361)
- hsa-mir-519b-3p (MIRT492362)
- hsa-mir-519a-3p (MIRT492363)
- hsa-mir-320e (MIRT492364)
- hsa-mir-4796-3p (MIRT492365)
- hsa-mir-548ah-5p (MIRT492366)
- hsa-mir-3609 (MIRT492367)
- hsa-mir-4429 (MIRT492368)
- hsa-mir-320d (MIRT492369)
- hsa-mir-320c (MIRT492370)
- hsa-mir-320b (MIRT492371)
- hsa-mir-320a (MIRT492372)
- hsa-mir-323a-3p (MIRT492373)
- hsa-mir-519d-3p (MIRT492374)
- hsa-mir-20b-5p (MIRT492375)
- hsa-mir-106b-5p (MIRT492376)
- hsa-mir-20a-5p (MIRT492377)
- hsa-mir-526b-3p (MIRT492378)
- hsa-mir-93-5p (MIRT492379)
- hsa-mir-17-5p (MIRT492380)
- hsa-mir-106a-5p (MIRT492381)
- hsa-mir-33b-5p (MIRT492382)
- hsa-mir-33a-5p (MIRT492383)
- hsa-mir-3180-5p (MIRT498085)
- hsa-mir-525-5p (MIRT498086)
- hsa-mir-520a-5p (MIRT498087)
- hsa-mir-4294 (MIRT498088)
- hsa-mir-6774-5p (MIRT498089)
- hsa-mir-635 (MIRT498090)
- hsa-mir-4766-5p (MIRT498091)
- hsa-mir-5590-3p (MIRT498092)
- hsa-mir-142-5p (MIRT498093)
- hsa-mir-577 (MIRT498094)
- hsa-mir-1264 (MIRT498095)
- hsa-mir-6507-3p (MIRT498096)
- hsa-mir-4309 (MIRT653969)
- hsa-mir-3198 (MIRT653970)
- hsa-mir-7977 (MIRT653971)
- hsa-mir-1289 (MIRT653972)
- hsa-mir-8082 (MIRT653973)
- hsa-mir-4534 (MIRT653974)
- hsa-mir-1273f (MIRT653975)
- hsa-mir-6845-3p (MIRT653976)
- hsa-mir-3927-5p (MIRT653977)
- hsa-mir-5588-3p (MIRT653978)
- hsa-mir-6514-5p (MIRT653979)
miRNA Products
- Search ViGene Biosciences for SEMA7A
Clone Products
- OriGene clones in human for SEMA7A
- OriGene ORF clones in human,mouse,rat for SEMA7A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for SEMA7A
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- Addgene plasmids for SEMA7A
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for SEMA7A gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SEMA7A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SEMA7A gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SEMA7A Gene
Localization for SEMA7A Gene
Subcellular locations from UniProtKB/Swiss-Prot for SEMA7A Gene
- Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Note=Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 1 |
| endoplasmic reticulum | 1 |
| extracellular | 1 |
| golgi apparatus | 1 |
| lysosome | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| vacuole | 1 |
No data available for Gene Ontology (GO) - Cellular Components for SEMA7A Gene
Pathways & Interactions for SEMA7A Gene
More details on SuperPathways for SEMA7A| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | Developmental Biology |
.64
|
|
| 2 | Semaphorin interactions | ||
| 3 | Axon guidance | ||
| 4 | Semaphorin Signaling |
Pathways by source for SEMA7A Gene
4 Reactome pathways for SEMA7A Gene
1 KEGG pathway for SEMA7A Gene
1 Qiagen pathway for SEMA7A Gene
Interacting Proteins for SEMA7A Gene
Selected Interacting proteins:
O75326-SEM7A_HUMAN
ENSP00000261918
for SEMA7A Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001649 | osteoblast differentiation | IDA | 16210410 |
| GO:0001755 | neural crest cell migration | IBA | -- |
| GO:0001934 | positive regulation of protein phosphorylation | IEA | -- |
| GO:0007229 | integrin-mediated signaling pathway | IDA | 12879062 |
| GO:0007411 | axon guidance | TAS | -- |
Transcripts for SEMA7A Gene
mRNA/cDNA for SEMA7A Gene
- (3) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (114) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SEMA7A Gene
CRISPR Products
-
OriGene CRISPR knockouts for SEMA7A
-
Santa Cruz Biotechnology (SCBT) CRISPR for SEMA7A
- GenScript: Design CRISPR guide RNA sequences for SEMA7A
miRNA Products
- Search ViGene Biosciences for SEMA7A
Clone Products
- OriGene clones in human for SEMA7A
- OriGene ORF clones in human,mouse,rat for SEMA7A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for SEMA7A
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for SEMA7A
Flow Cytometry Products
Expression for SEMA7A Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Tube (Nervous System)
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
- Brain (Nervous System)
- Gut Tube (Gastrointestinal Tract)
- Kidney (Urinary System)
- Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for SEMA7A Gene
This gene is overexpressed in Spleen (x5.0) and Brain - Spinal cord (cervical c-1) (x4.0).
This gene is overexpressed in Vitreous humor (39.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SEMA7A Gene
SOURCE GeneReport for Unigene cluster for SEMA7A Gene Hs.24640
mRNA Expression by UniProt/SwissProt for SEMA7A Gene
O75326-SEM7A_HUMAN
Tissue specificity:
Detected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level). Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney.
Primer Products
-
OriGene qPCR primer pairs for SEMA7A
-
OriGene qPCR primer pairs and template standards for SEMA7A
No data available for Protein tissue co-expression partners for SEMA7A Gene
Orthologs for SEMA7A Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | SEMA7A 35 |
|
||
| SEMA7A 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | SEMA7A 35 |
|
||
| SEMA7A 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Sema7a 35 |
|
||
| Sema7a 16 |
|
||||
| Sema7a 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | SEMA7A 35 |
|
||
| SEMA7A 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Sema7a 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | SEMA7A 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SEMA7A 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | SEMA7A 35 |
|
||
| SEMA7A 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | SEMA7A 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | sema7a 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | sema7a 35 |
|
||
| SEMA7A 36 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | Sema-1a 36 |
|
OneToMany | |
| Sema-1b 36 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | mab-20 36 |
|
OneToMany | |
| smp-1 36 |
|
OneToMany | |||
| smp-2 36 |
|
OneToMany |
- Species with no ortholog for SEMA7A:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for SEMA7A Gene
(4) SIMAP similar genes for SEMA7A Gene using alignment to 3 proteins:
Variants for SEMA7A Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for SEMA7A Gene
- SEM7A_HUMAN-O75326
- Genetic variations in SEMA7A define the John Milton Hagen blood group system (JMH) [MIM:614745]. Three different JMH phenotypes have been identified based on the presence or absence of the high-frequency JMH antigen: JMH-weak, JMH-negative, and JMH-variant. The JMH-weak and -negative phenotypes can be either acquired or inherited and are characterized by a reduction or complete loss of JMH expression on red blood cells. Individuals with the JMH-variant phenotype are usually JMH-positive and have alloantibodies compatible with JMH-negative red blood cells. The JMH-variant phenotype results from rare SEMA7A missense variants.
| SNP ID | Clin | Chr 15 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs16968733 | - | 74,418,297(+) | TGTGG(A/T)GCCGA | intron-variant, reference, missense, utr-variant-5-prime | |
| rs55637216 | - | 74,417,376(-) | CATCC(A/G)GGGCG | reference, missense | |
| rs56367230 | - | 74,417,377(-) | GCATC(C/T)GGGGC | reference, missense | |
| VAR_038838 | - | ||||
| VAR_038839 | - |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2406n71 | CNV | Loss | 21882294 |
| nsv904353 | CNV | Gain | 21882294 |
| nsv904354 | CNV | Gain+Loss | 21882294 |
| dgv2407n71 | CNV | Gain | 21882294 |
| esv2749879 | CNV | Deletion | 23290073 |
| dgv2408n71 | CNV | Gain | 21882294 |
| dgv2409n71 | CNV | Loss | 21882294 |
| dgv2410n71 | CNV | Gain | 21882294 |
| dgv2411n71 | CNV | Loss | 21882294 |
| nsv904369 | CNV | Gain | 21882294 |
| dgv2412n71 | CNV | Loss | 21882294 |
| nsv904371 | CNV | Loss | 21882294 |
| nsv904373 | CNV | Loss | 21882294 |
| dgv2413n71 | CNV | Loss | 21882294 |
| esv24909 | CNV | Loss | 19812545 |
Residual Variation Intolerance Score:
39.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.79;
47.42% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for SEMA7A Gene
- Human Gene Mutation Database (HGMD)
- SEMA7A
Disorders for SEMA7A Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chromosome 15q24 deletion syndrome |
|
|
| hemoglobinuria |
|
|
| exotropia |
|
|
Search SEMA7A in MalaCards
View complete list of genes associated with diseases
Relevant External Links for SEMA7A
No data available for UniProtKB/Swiss-Prot and Genatlas for SEMA7A Gene
Publications for SEMA7A Gene
- New eukaryotic semaphorins with close homology to semaphorins of DNA viruses. (PMID: 9721204) Lange C. … Ensser A. (Genomics 1998) 2 3 4 67
- Plexin C1, a receptor for semaphorin 7a, inactivates cofilin and is a potential tumor suppressor for melanoma progression. (PMID: 18987670) Scott G.A. … Fender A. (J. Invest. Dermatol. 2009) 3 23
- The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis. (PMID: 19318806) Lazova R. … Scott G. (Am J Dermatopathol 2009) 3 23
- Semaphorin 7a promotes spreading and dendricity in human melanocytes through beta1-integrins. (PMID: 17671519) Scott G.A. … Fricke A.F. (J. Invest. Dermatol. 2008) 3 23
- Rapid detection of JMH antibodies with recombinant Sema7A (CD108) protein and the particle gel immunoassay. (PMID: 18422858) Seltsam A. … Salama A. (Transfusion 2008) 3 23
Products for SEMA7A Gene
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- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for SEMA7A
- Cloud-Clone Corp. Proteins for SEMA7A
- Cloud-Clone Corp Assay Kits for SEMA7A
- Taconic Biosciences Mouse Models for SEMA7A
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Addgene plasmids for SEMA7A
- antibodies-online Antibodies for SEMA7A: See all 79
- antibodies-online Kits for SEMA7A: See all 39
- antibodies-online Proteins for SEMA7A: See all 7
- Search antibodies-online for peptides
- GeneTex SEMA7A antibody for SEMA7A
- Search GeneTex for Proteins for SEMA7A
- ViGene Biosciences adenoviral particle packaged cDNA for SEMA7A gene
- ViGene Biosciences lentiviral particle packaged cDNA for SEMA7A gene
- ViGene Biosciences lentiviral particle packaged cDNA for SEMA7A gene
- ViGene Biosciences ready-to-package AAV shRNAs for SEMA7A gene
- ViGene Biosciences ready-to-package AAV shRNAs for SEMA7A gene
- ViGene Biosciences ready-to-package AAV shRNAs for SEMA7A gene
- Search ViGene Biosciences for SEMA7A
- Search ViGene Biosciences for SEMA7A
- Santa Cruz Biotechnology (SCBT) Antibodies for SEMA7A
- Search Santa Cruz Biotechnology (SCBT) for SEMA7A siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SEMA7A
Sources for SEMA7A Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon