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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEMA6C Gene

protein-coding   GIFtS: 56
GCID: GC01M151104

Sema Domain, Transmembrane Domain (TM), And Cytoplasmic...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sema Domain, Transmembrane Domain (TM), And Cytoplasmic Domain,
(Semaphorin) 6C1 2
     m-SemaY22
Sema Y2 3     semaphorin-6C2
SEMAY2 3     semaphorin-Y2
M-Sema Y21     KIAA18693
m-SemaY2     Semaphorin-Y3

External Ids:    HGNC: 107401   Entrez Gene: 105002   Ensembl: ENSG000001434347   OMIM: 6092945   UniProtKB: Q9H3T23   

Export aliases for SEMA6C gene to outside databases

Previous GC identifers: GC01M148946 GC01M146851 GC01M147879 GC01M148320 GC01M147918 GC01M149370 GC01M122481


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SEMA6C Gene:
This gene encodes a member of the semaphorin family. Semaphorins represent important molecular signals controlling
multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural
regeneration. (provided by RefSeq, May 2010)

GeneCards Summary for SEMA6C Gene: 
SEMA6C (sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C) is a protein-coding gene. Diseases associated with SEMA6C include status epilepticus, and schizophrenia. GO annotations related to this gene include semaphorin receptor binding and receptor activity. An important paralog of this gene is SEMA6D.

UniProtKB/Swiss-Prot: SEM6C_HUMAN, Q9H3T2
Function: Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop
signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in
the maintenance and remodeling of neuronal connections

Gene Wiki entry for SEMA6C Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEMA6C gene promoter:
         PPAR-alpha   Spz1   Tal-1   MAZR   RREB-1   Olf-1   Nkx2-5   TGIF   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSEMA6C promoter sequence
   Search SABiosciences Chromatin IP Primers for SEMA6C

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEMA6C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.2   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21.2

SEMA6C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEMA6C gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M151104:  view genomic region     (about GC identifiers)

Start:
151,104,161 bp from pter      End:
151,119,140 bp from pter
Size:
14,980 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SEM6C_HUMAN, Q9H3T2 (See protein sequence)
Recommended Name: Semaphorin-6C precursor  
Size: 930 amino acids; 99686 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein
Sequence caution: Sequence=BAB47498.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: D3DV15 Q5JR71 Q5JR72 Q5JR73 Q8WXT8 Q8WXT9 Q8WXU0 Q96JF8
Alternative splicing: 3 isoforms:  Q9H3T2-1   Q9H3T2-2   Q9H3T2-3   

Explore the universe of human proteins at neXtProt for SEMA6C: NX_Q9H3T2

Explore proteomics data for SEMA6C at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H3T2

  • SEMA6C Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SEMA6C Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001171532.1  NP_001171533.1  NP_112175.2  

    ENSEMBL proteins: 
     ENSP00000357909   ENSP00000357908   ENSP00000357910   ENSP00000344148  

    Human Recombinant Protein Products for SEMA6C: 
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    Novus Biologicals SEMA6C Proteins
    Novus Biologicals SEMA6C Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SEMA6C 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    SEMA6C for ontologies           About GeneDecksing



    SEMA6C Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SEMA: Semaphorins

    5/7 InterPro protein domains (see all 7):
     IPR003659 Plexin-like
     IPR002165 Plexin_repeat
     IPR016201 Plexin-like_fold
     IPR015514 Semaphorin_6C
     IPR027231 Semaphorin

    Graphical View of Domain Structure for InterPro Entry Q9H3T2

    ProtoNet protein and cluster: Q9H3T2

    1 Blocks protein domain: IPB001627 Semaphorin/CD100 antigen

    UniProtKB/Swiss-Prot: SEM6C_HUMAN, Q9H3T2
    Similarity: Belongs to the semaphorin family
    Similarity: Contains 1 PSI domain
    Similarity: Contains 1 Sema domain


    SEMA6C for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SEM6C_HUMAN, Q9H3T2
    Function: Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop
    signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in
    the maintenance and remodeling of neuronal connections

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity IEA--
    GO:0005515protein binding ----
    GO:0030215semaphorin receptor binding IEA--
         
    SEMA6C for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Sema6c):
     behavior/neurological  immune system  integument 

    SEMA6C for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Sema6ctm1Matl for SEMA6C

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SEMA6C 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SEMA6C

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SEMA6C 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SEMA6C 

    miRNA
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    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate SEMA6C (see all 14):
    hsa-miR-3910 hsa-miR-658 hsa-miR-1301 hsa-miR-1184 hsa-miR-124 hsa-miR-149 hsa-miR-625 hsa-miR-3131
    SwitchGear 3'UTR luciferase reporter plasmidSEMA6C 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SEMA6C
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    Gene Editing
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): SEMA6C (NM_030913)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SEMA6C
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                         Customized lentivirus expression plasmids for stable overexpression of SEMA6C 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEMA6C


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SEMA6C About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Axon guidance
    Axon guidance

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for SEMA6C):
        Axon guidance


    SEMA6C for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEMA6C

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development ----
    GO:0007411axon guidance IEA--

    SEMA6C for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SEMA6C (SEM6C)

    Search CenterWatch for drugs/clinical trials and news about SEMA6C / SEM6C

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SEMA6C gene (3 alternative transcripts): 
    NM_001178061.1  NM_001178062.1  NM_030913.4  

    Unigene Cluster for SEMA6C:

    Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
    Hs.516316  [show with all ESTs]
    Unigene Representative Sequence: NM_001178061
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368913 ENST00000368912 ENST00000368914(uc001ewv.3 uc001ewu.3 uc001eww.3 uc009wml.2)
    ENST00000341697 ENST00000479820 ENST00000464018 ENST00000489944 ENST00000485745

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SEMA6C
    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate SEMA6C (see all 14):
    hsa-miR-3910 hsa-miR-658 hsa-miR-1301 hsa-miR-1184 hsa-miR-124 hsa-miR-149 hsa-miR-625 hsa-miR-3131
    SwitchGear 3'UTR luciferase reporter plasmidSEMA6C 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SEMA6C
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEMA6C
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 3): SEMA6C (NM_030913)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SEMA6C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEMA6C
    Sirion Biotech Customized lentivirus for stable overexpression of SEMA6C 
                         Customized lentivirus expression plasmids for stable overexpression of SEMA6C 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEMA6C
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEMA6C

    Additional mRNA sequence: 

    AB022434.1 AF055020.1 AF339152.1 AF339153.1 AF339154.1 AK302862.1 AK311613.1 AL122064.1 
    BC114521.1 BC114623.1 

    9 DOTS entries:

    DT.95155216  DT.454780  DT.97819424  DT.102823833  DT.97837576  DT.92422982  DT.97837577  DT.70101876 
    DT.91657069 

    24/55 AceView cDNA sequences (see all 55):

    BX279977 AI124683 CD671385 C20820 BP348665 NM_030913 AB058772 AW074352 
    BG120187 W19822 AW028659 AI884804 AF339154 BM680184 AU279414 W32459 
    AF339153 BF931982 BI522560 AF339152 AL705352 AU252719 BM724963 BE253393 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for SEMA6C (see all 12)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14 ^
    SP1:              -     -     -     -           -           -     -                                                                                             
    SP2:                                                                                                                                                            
    SP3:              -     -     -     -           -     -     -                                                                                                   
    SP4:                                                                                                                    -                                       
    SP5:                                                                                                                                                            

    ExUns: 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b
    SP1:                                                      
    SP2:                                      -               
    SP3:                                                      
    SP4:                                                      
    SP5:                                                      


    ECgene alternative splicing isoforms for SEMA6C

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SEMA6C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SEMA6C Expression
    About this image


    See SEMA6C Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SEMA6C

    SOURCE GeneReport for Unigene cluster: Hs.516316

    UniProtKB/Swiss-Prot: SEM6C_HUMAN, Q9H3T2
    Tissue specificity: In adult tissues, expressed only in skeletal muscle

        SABiosciences Custom PCR Arrays for SEMA6C
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEMA6C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SEMA6C gene from 2/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sema6c1 , 5 sema domain, transmembrane domain (TM), and cytoplasmic more1, 5 86.34(n)1
    88.24(a)1
      3 (40.74 cM)5
    203601  NM_011351.11  NP_035481.11 
     951604575 
    chicken
    (Gallus gallus)
    Aves LOC1008598921 semaphorin-6C-like 57.39(n)
    52.31(a)
      100859892  XM_003642677.1  XP_003642725.1 


    ENSEMBL Gene Tree for SEMA6C (if available)
    TreeFam Gene Tree for SEMA6C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SEMA6C gene
    SEMA6D2  SEMA6B2  SEMA5A2  SEMA6A2  SEMA7A2  SEMA5B2  
    9 SIMAP similar genes for SEMA6C using alignment to 3 protein entries:     SEM6C_HUMAN (see all proteins):
    DKFZp434M231    SEMA6D    SEMA6A    SEMA6B    SEMA5B    SEMA3A
    SEMA4A    SEMA4D    SEMA3F

    SEMA6C for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/428 SNPs in SEMA6C are shown (see all 428)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs114090061,2
    C--151113474(+) AAAAA-/A/GTTCAT 3 -- int1 trp32NA CSA 4
    rs106102631,2
    C--151113693(+) TTATT-/GGTG  
            
    GGTGG
    3 -- int11Minor allele frequency- GGTG:0.00CSA 2
    rs38410581,2
    C,F--151120523(+) GATCTA/-AAAAA 3 -- us2k1 tfbs33Minor allele frequency- -:0.50NA CSA 6
    rs1898873911,2
    --157605352(+) GAGTTG/TGCCCG 3 -- ds50010--------
    rs49710021,2
    C,F,A,H--157605460(+) CTGCCG/TCCTGC 3 -- ds500111Minor allele frequency- T:0.26NA WA CSA EA 376
    rs1440999851,2
    --157605471(+) GTTAGA/GCCTTA 3 -- ds50010--------
    rs1155554601,2
    C,F--157605482(+) AAGCGT/CTGTTA 3 -- ds50011Minor allele frequency- C:0.05WA 118
    rs115866541,2
    C,F,H--157605662(+) GGGGTG/CGCTAA 3 -- ds50012Minor allele frequency- C:0.07NA 126
    rs1995731411,2
    --157605714(+) CTCCT-/TAAG  
            
    TAAGA
    3 -- ds50010--------
    rs49710031,2
    C,F,A,H--157605725(+) AGAGCT/CGGGGG 3 -- ds500111Minor allele frequency- C:0.22WA NA CSA EA 375

    HapMap Linkage Disequilibrium report for SEMA6C (151104161 - 151119140 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SEMA6C:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv2n68CNV Loss17160897
    dgv385n71CNV Loss21882294
    nsv522840CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609294    OMIM disorders: --

    3 diseases for SEMA6C:    About MalaCards
    status epilepticus    schizophrenia    neuronitis


    SEMA6C for disorders           About GeneDecksing

    Genetic Association Database (GAD): SEMA6C
    Human Genome Epidemiology (HuGE) Navigator: SEMA6C (1 document)

    Export disorders for SEMA6C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SEMA6C gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with SEMA6C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification, characterization, and functional study of the two novel human members of the semaphorin gene family. (PubMed id 12110693)1, 2, 3 Qu X.... He F. (2002)
    2. Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence. (PubMed id 19054571)1, 4 GregA^rio S.P....Dias-Neto E. (2009)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (2001)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    6. Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. (PubMed id 12878157)1 Imabayashi H.... Umezawa A. (2003)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Emerging roles for semaphorins in neural regeneration. (PubMed id 11245885)1 Pasterkamp R.J. and Verhaagen J. (2001)
    9. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (1997)
    10. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1 Andersson B.... Gibbs R.A. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10500 HGNC: 10740 AceView: SEMA6C Ensembl:ENSG00000143434 euGenes: HUgn10500
    ECgene: SEMA6C Kegg: 10500 H-InvDB: SEMA6C

    (According to HUGE)
    About This Section
    HUGE: KIAA1869

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SEMA6C Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SEMA6C gene:
    Search GeneIP for patents involving SEMA6C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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