SEMA5B Gene(Protein Coding)

Semaphorin 5B

GCID:: GC03M122909

GIFtS:: 58

Genes Participants

Aliases for SEMA5B Gene

Semaphorin 5B ² ³
Sema Domain, Seven Thrombospondin Repeats (Type 1 And Type 1-Like), Transmembrane Domain (TM) And Short Cytoplasmic Domain, (Semaphorin) 5B ² ³ ⁵
SEMAG ³ ⁴
KIAA1445 ⁴
SemG ³

External Ids for SEMA5B Gene

HGNC: 10737
Entrez Gene: 54437
Ensembl: ENSG00000082684
OMIM: 609298
UniProtKB: Q9P283

Previous HGNC Symbols for SEMA5B Gene

SEMAG

Previous GeneCards Identifiers for SEMA5B Gene

GC03M119346
GC03M122576
GC03M123909
GC03M123948
GC03M124110
GC03M122628
GC03M120001

Export aliases for SEMA5B gene to outside databases

Summaries for SEMA5B Gene

Entrez Gene Summary for SEMA5B Gene

This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

GeneCards Summary for SEMA5B Gene

SEMA5B (Semaphorin 5B) is a Protein Coding gene. Among its related pathways are Axon guidance and Infectious disease. GO annotations related to this gene include receptor activity. An important paralog of this gene is SEMA6C.

UniProtKB/Swiss-Prot for SEMA5B Gene

SEM5B_HUMAN,Q9P283

May act as positive axonal guidance cues.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SEMA5B Gene

Genomics for SEMA5B Gene

Regulatory Elements for SEMA5B Gene

Enhancers for SEMA5B Gene

GeneHancer Identifier	Score	Enhancer Sources	TSS distance (kb)	Number of Genes Away	Size (kb)	Transcription Factor Binding Sites within enhancer	Other Gene Targets for Enhancer

Enhancers around SEMA5B on UCSC Golden Path with GeneCards custom track

Promoters for SEMA5B Gene

Ensembl Regulatory Elements (ENSRs)	TSS Distance (bp)	Size (bp)	Binding Sites for Transcription Factors within promoters

ENSRs around SEMA5B on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the SEMA5B gene promoter:

See All at QIAGEN

Regulatory Element Products

Genomic Location for SEMA5B Gene

Chromosome:: 3

Start:: 122,909,193 bp from pter
End:: 123,028,605 bp from pter

Size:: 119,413 bases
Orientation:: Minus strand

Genomic View for SEMA5B Gene

Genes around SEMA5B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:

3q21.1 by Ensembl
3q21.1 by Entrez Gene
3q21.1 by HGNC

SEMA5B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

Genomic Location for SEMA5B Gene — Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SEMA5B Gene

Proteins for SEMA5B Gene

Protein details for SEMA5B Gene (UniProtKB/Swiss-Prot)
Protein Symbol:

Q9P283-SEM5B_HUMAN

Recommended name:

Semaphorin-5B

Protein Accession:

Q9P283

Secondary Accessions:
- A8K5U2
- B7Z393
- F8W9U8
- Q6DD89
- Q6UY12
- Q9NW17
Protein attributes for SEMA5B Gene
Size:

1151 amino acids

Molecular mass:

125913 Da
Quaternary structure:

No Data Available

SequenceCaution:
Sequence=BAA91570.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA95969.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Alternative splice isoforms for SEMA5B Gene
UniProtKB/Swiss-Prot:
Q9P283-1

Q9P283-2

Q9P283-3

Q9P283-4

neXtProt entry for SEMA5B Gene

Proteomics data for SEMA5B Gene at MOPED

Protein Expression for SEMA5B Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for SEMA5B Gene

Glycosylation at Asn 153, Asn 236, Asn 345, Asn 436, and Thr 788
- NX_Q9P283
Modification sites at PhosphoSitePlus
- Q9P283

Other Protein References for SEMA5B Gene

ENSEMBL proteins:

REFSEQ proteins:

Antibody Products

EMD Millipore Complete listing of Mono and Polychlonal Antibodies for SEMA5B

Browse R&D Systems for Antibodies

Browse OriGene Antibodies

Novus Biologicals Antibodies for SEMA5B

Search for Antibodies for SEMA5B at Abcam

Cloud-Clone Corp. Antibodies for SEMA5B

Search Invitrogen Antibodies for SEMA5B

antibodies-online Antibodies for SEMA5B: See all 37

Search GeneTex for Antibodies for SEMA5B

Santa Cruz Biotechnology (SCBT) Antibodies for SEMA5B

Protein Products

Browse Purified and Recombinant Proteins at EMD Millipore

R&D Systems Proteins and Enzymes for SEMA5B (Semaphorin 5B)

Browse Enzo Life Sciences for proteins

OriGene Purified Proteins for SEMA5B
- NM_001031702
Search Origene for MassSpec and Protein Over-expression Lysates for SEMA5B
Origene Custom Protein Services for SEMA5B

GenScript Custom Purified and Recombinant Proteins Services for SEMA5B

Novus Biologicals proteins and lysates for SEMA5B

Browse ProSpec Recombinant Proteins

Cloud-Clone Corp. Proteins for SEMA5B
- RPL926Hu01
- RPL926Hu02

Search eBioscience for SEMA5B related proteins

antibodies-online Proteins for SEMA5B: See all 9
Search antibodies-online for peptides

Search GeneTex for Proteins for SEMA5B

Search for Proteins for SEMA5B at Abcam

Assay Products

Browse Kits and Assays available from EMD Millipore

Browse R&D Systems for biochemical assays

GenScript Custom Assay Services for SEMA5B

Browse Enzo Life Sciences for kits & assays

Browse Assay Kits at Cloud-Clone Corp.

Search eBioscience for SEMA5B related elisas

Search antibodies-online for kits

Search for Assays for SEMA5B at Abcam

No data available for DME Specific Peptides for SEMA5B Gene

Domains & Families for SEMA5B Gene

Gene Families for SEMA5B Gene

HGNC:

736 : Semaphorins

Protein Domains for SEMA5B Gene

InterPro:

Blocks:

Thrombospondin, type I

ProtoNet:

Q9P283

Suggested Antigen Peptide Sequences for SEMA5B Gene

GenScript: Design optimal peptide antigens:

Semaphorin-5B (SEM5B_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9P283

UniProtKB/Swiss-Prot:

SEM5B_HUMAN :

Contains 1 PSI domain.
Belongs to the semaphorin family.

Domain:

Contains 1 PSI domain.
Contains 1 Sema domain.
Contains 5 TSP type-1 domains.

Family:

Belongs to the semaphorin family.

Function for SEMA5B Gene

Molecular function for SEMA5B Gene

UniProtKB/Swiss-Prot Function:

May act as positive axonal guidance cues.

SEM5B_HUMAN,Q9P283

Phenotypes for SEMA5B Gene

MGI mutant phenotypes for SEMA5B:

inferred from 3 alleles

GenomeRNAi human phenotypes for SEMA5B:

Animal Models for SEMA5B Gene

MGI Knock Outs for SEMA5B:

Sema5b ^{tm1a(EUCOMM)Wtsi}
Sema5b ^tm1.2Alk

Animal Model Products

Taconic Biosciences Mouse Models for SEMA5B
- Sema5b

ViGene Biosciences lentiviral particle packaged cDNA for SEMA5B gene
- LH813355
ViGene Biosciences ready-to-package AAV shRNAs for SEMA5B gene
- SH813355
Search ViGene Biosciences for SEMA5B

CRISPR Products

OriGene CRISPR knockouts for SEMA5B
- KN209657
- KN315507

Santa Cruz Biotechnology (SCBT) CRISPR for SEMA5B

GenScript: Design CRISPR guide RNA sequences for SEMA5B

miRNA for SEMA5B Gene

miRTarBase miRNAs that target SEMA5B

miRNA Products

Search ViGene Biosciences for SEMA5B

Inhibitory RNA Products

Origene RNAi, shRNA, rat_shrna, mouse_rna, and siRNA products in human, mouse, rat for SEMA5B
Browse OriGene Inhibitory RNA Products For SEMA5B

ViGene Biosciences ready-to-package AAV shRNAs for SEMA5B gene
- SH813355

Search Santa Cruz Biotechnology (SCBT) for SEMA5B siRNA/shRNA

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SEMA5B Gene

Localization for SEMA5B Gene

Subcellular locations from UniProtKB/Swiss-Prot for SEMA5B Gene

Membrane; Single-pass type III membrane protein.

Q9P283-SEM5B_HUMAN

Subcellular locations from

COMPARTMENTS

Jensen Localization Image for SEMA5B Gene

Compartment	Confidence
plasma membrane	3
cytosol	2
extracellular	1
nucleus	1
peroxisome	1

No data available for Gene Ontology (GO) - Cellular Components for SEMA5B Gene

Pathways & Interactions for SEMA5B Gene

SuperPathways for SEMA5B Gene

More details on SuperPathways for SEMA5B

	Superpath	Contained pathways
1	O-glycosylation of TSR domain-containing proteins	Defective B3GALTL causes Peters-plus syndrome (PpS) .95	O-glycosylation of TSR domain-containing proteins .95
2	Diseases associated with O-glycosylation of proteins	Diseases associated with O-glycosylation of proteins .70	Diseases of glycosylation .70
3	Transport to the Golgi and subsequent modification	Post-translational protein modification .49	Metabolism of proteins .47
4	Axon guidance	Axon guidance 1
5	Infectious disease	Disease .48

Pathways by source for SEMA5B Gene

8 Reactome pathways for SEMA5B Gene

1 KEGG pathway for SEMA5B Gene

Axon guidance

Interacting Proteins for SEMA5B Gene

http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000350215%0d%0a9606.ENSP00000230419%0d%0a9606.ENSP00000356000%0d%0a9606.ENSP00000318472%0d%0a9606.ENSP00000359085%0d%0a9606.ENSP00000364860%0d%0a — STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins: Q9P283-SEM5B_HUMAN ENSP00000350215 for SEMA5B Gene via MINT STRING I2D

Symbol	External ID(s)	Details
C11orf58	O00193 ¹⁹ ²¹ ENSP00000228136 ²⁰	MINT-8249876 STRING: ENSP00000228136 I2D: score=2
ANXA7	P20073 ¹⁹ ²¹	MINT-8248702 I2D: score=2
FAM118B	Q9BPY3 ¹⁹ ²¹	MINT-8255200 I2D: score=2
MRPL44	Q9H9J2 ¹⁹ ²¹	MINT-8263379 I2D: score=2
NUDT21	O43809 ¹⁹ ²¹	MINT-8264512 I2D: score=2

Gene Ontology (GO) - Biological Process for SEMA5B Gene

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001755	neural crest cell migration	IBA	--
GO:0030335	positive regulation of cell migration	IBA	--
GO:0048843	negative regulation of axon extension involved in axon guidance	IBA	--
GO:0050908	detection of light stimulus involved in visual perception	IEA	--

No data available for SIGNOR curated interactions for SEMA5B Gene

Drugs & Compounds for SEMA5B Gene

No Compound Related Data Available

Drug Products

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SEMA5B

Browse compounds at ApexBio

Transcripts for SEMA5B Gene

mRNA/cDNA for SEMA5B Gene

(7) REFSEQ mRNAs :

(11) Additional mRNA sequences :

(53) Selected AceView cDNA sequences:

(11) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SEMA5B Gene

Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B:

Hs.210870

Representative Sequences:

NM_001256346

CRISPR Products

OriGene CRISPR knockouts for SEMA5B
- KN209657
- KN315507

Santa Cruz Biotechnology (SCBT) CRISPR for SEMA5B

GenScript: Design CRISPR guide RNA sequences for SEMA5B

miRNA Products

Search ViGene Biosciences for SEMA5B

Inhibitory RNA Products

Origene RNAi, shRNA, rat_shrna, mouse_rna, and siRNA products in human, mouse, rat for SEMA5B
Browse OriGene Inhibitory RNA Products For SEMA5B

ViGene Biosciences ready-to-package AAV shRNAs for SEMA5B gene
- SH813355

Search Santa Cruz Biotechnology (SCBT) for SEMA5B siRNA/shRNA

Clone Products

OriGene clones in human for SEMA5B
OriGene ORF clones in human,mouse,rat for SEMA5B
Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling

GenScript: Next-day shipping cDNA clones in your preferred vector

Browse Sino Biological cDNA Clones

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat

Search Addgene for plasmids for SEMA5B

Flow Cytometry Products

eBioscience FlowRNA Probe Sets

Alternative Splicing Database (ASD) splice patterns (SP) for SEMA5B Gene

ExUns:	1	^	2a	·	2b	·	2c	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9	^	10a	·	10b	^	11	^	12	^	13	^	14a	·	14b	^	15	^	16a	·	16b	^	17	^	18	^	19	^
SP1:			-		-		-		-		-		-																								-
SP2:									-		-		-																								-
SP3:													-																								-
SP4:									-		-		-		-						-		-
SP5:											-		-
SP6:
SP7:									-		-		-		-
SP8:
SP9:

ExUns:	20	^	21	^	22	^	23	^	24	^	25a	·	25b	^	26a	·	26b	·	26c	^	27a	·	27b
SP1:															-
SP2:													-		-
SP3:													-		-
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:

Relevant External Links for SEMA5B Gene

GeneLoc Exon Structure for: SEMA5B
ECgene alternative splicing isoforms for: SEMA5B

Expression for SEMA5B Gene

mRNA expression in normal human tissues for SEMA5B Gene

mRNA expression by BioGPS for SEMA5B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
- Hippocampus
- Cerebellum
- Cerebral Cortex
- Lateral Ventricle
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
Eye (Sensory Organs)
- Retina

mRNA differential expression in normal tissues according to GTEx for SEMA5B Gene

This gene is overexpressed in Brain - Cortex (x5.5) and Brain - Hippocampus (x4.2).

Protein differential expression in normal tissues from HIPED for SEMA5B Gene

This gene is overexpressed in Adipocyte (24.2), Esophagus (17.9), and CD4 Tcells (16.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SEMA5B Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SEMA5B Gene

Integrated proteomics: cell line protein expression from ProteomicsDB, MOPED and MaxQB for SEMA5B Gene

SOURCE GeneReport for Unigene cluster for SEMA5B Gene Hs.210870

Primer Products

OriGene qPCR primer pairs for SEMA5B
- HP202904

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SEMA5B Gene

Orthologs for SEMA5B Gene

This gene was present in the common ancestor of animals.

Orthologs for SEMA5B Gene

Organism	Taxonomy	Gene	Similarity	Type	Details
cow (Bos Taurus)	Mammalia	SEMA5B ³⁵	90.88 (n) 94.57 (a)		784494 XM_002684809.2 XP_002684855.1
cow (Bos Taurus)	Mammalia	SEMA5B ³⁶	94 (a)	OneToOne	1:67840125-67878028
dog (Canis familiaris)	Mammalia	SEMA5B ³⁵	88.57 (n) 90.88 (a)		100687386 XM_005639649.1 XP_005639706.1
dog (Canis familiaris)	Mammalia	SEMA5B ³⁶	88 (a)	OneToOne	33:25971182-26023674
mouse (Mus musculus)	Mammalia	Sema5b ³⁵	89.08 (n) 93.6 (a)		20357 NM_013661.2 NP_038689.2
		Sema5b ¹⁶			35541145
		Sema5b ³⁶	94 (a)	OneToOne	16:35541145-35664732
chimpanzee (Pan troglodytes)	Mammalia	SEMA5B ³⁵	98.62 (n) 98.37 (a)		460636 XM_516697.4 XP_516697.4
chimpanzee (Pan troglodytes)	Mammalia	SEMA5B ³⁶	98 (a)	OneToOne	3:126290169-126344045
rat (Rattus norvegicus)	Mammalia	Sema5b ³⁵	88.92 (n) 93.37 (a)		303901 NM_001107091.1 NP_001100561.1
oppossum (Monodelphis domestica)	Mammalia	SEMA5B ³⁶	83 (a)	OneToOne	4:87665235-87819823
platypus (Ornithorhynchus anatinus)	Mammalia	-- ³⁶	15 (a)	ManyToMany	Contig22822:407-7202
chicken (Gallus gallus)	Aves	SEMA5B ³⁵	71.99 (n) 78.52 (a)		424248 XM_422096.3 XP_422096.2
chicken (Gallus gallus)	Aves	SEMA5B ³⁶	76 (a)	OneToOne	7:26051937-26233120
lizard (Anolis carolinensis)	Reptilia	SEMA5B ³⁶	78 (a)	OneToOne	1:83129175-83269448
African clawed frog (Xenopus laevis)	Amphibia	MGC68835 ³⁵			BC059288.1
zebrafish (Danio rerio)	Actinopterygii	sema5ba ³⁵	67.4 (n) 69.18 (a)		556471 XM_679287.3 XP_684379.3
		sema5ba ³⁶	66 (a)	OneToMany	9:38528660-38689365
		sema5bb ³⁶	63 (a)	OneToMany	6:3954418-4015752
fruit fly (Drosophila melanogaster)	Insecta	CG4383 ³⁷	36 (a)
		Sema-1a ³⁷	40 (a)
		Sema-1b ³⁷	34 (a)
		Sema-2a ³⁷	35 (a)
		Sema-5c ³⁷	37 (a)
		Sema-5c ³⁵	51.04 (n) 42.73 (a)		37066 NM_137449.2 NP_611293.3
		Sema-5c ³⁶	37 (a)	OneToMany	3L:12060611-12074927
African malaria mosquito (Anopheles gambiae)	Insecta	AgaP_AGAP002424 ³⁵	50.3 (n) 41.01 (a)		1273536 XM_312521.5 XP_312521.5
worm (Caenorhabditis elegans)	Secernentea	C36B7.5a ³⁷	31 (a)
		C36B7.5b ³⁷	31 (a)
		mab-20 ³⁷	27 (a)
		smp-2 ³⁷	25 (a)

Species with no ortholog for SEMA5B:

A. gosspyii yeast (Ashbya gossypii)
Actinobacteria (Mycobacterium tuberculosis)
Alicante grape (Vitis vinifera)
alpha proteobacteria (Wolbachia pipientis)
amoeba (Dictyostelium discoideum)
Archea (Pyrococcus horikoshii)
baker's yeast (Saccharomyces cerevisiae)
barley (Hordeum vulgare)
beta proteobacteria (Neisseria meningitidis)
bread mold (Neurospora crassa)
Chromalveolata (Phytophthora infestans)
common water flea (Daphnia pulex)
corn (Zea mays)
E. coli (Escherichia coli)
filamentous fungi (Aspergillus nidulans)
Firmicute bacteria (Streptococcus pneumoniae)
fission yeast (Schizosaccharomyces pombe)
green algae (Chlamydomonas reinhardtii)
honey bee (Apis mellifera)
K. lactis yeast (Kluyveromyces lactis)
loblloly pine (Pinus taeda)
malaria parasite (Plasmodium falciparum)
medicago trunc (Medicago Truncatula)
moss (Physcomitrella patens)
orangutan (Pongo pygmaeus)
pig (Sus scrofa)
rainbow trout (Oncorhynchus mykiss)
rice (Oryza sativa)
rice blast fungus (Magnaporthe grisea)
schistosome parasite (Schistosoma mansoni)
sea anemone (Nematostella vectensis)
sea squirt (Ciona intestinalis)
sea squirt (Ciona savignyi)
sea urchin (Strongylocentrotus purpuratus)
sorghum (Sorghum bicolor)
soybean (Glycine max)
stem rust fungus (Puccinia graminis)
sugarcane (Saccharum officinarum)
thale cress (Arabidopsis thaliana)
tomato (Lycopersicon esculentum)
toxoplasmosis (Toxoplasma gondii)
Trichoplax (Trichoplax adhaerens)
tropical clawed frog (Silurana tropicalis)
wheat (Triticum aestivum)

Evolution for SEMA5B Gene

ENSEMBL:: Gene Tree for SEMA5B (if available)
TreeFam:: Gene Tree for SEMA5B (if available)

Paralogs for SEMA5B Gene

SEMA6C ⁵
SEMA6D ⁵
SEMA6A ⁵
SEMA6B ⁵
SEMA7A ⁵
SEMA5A ⁵

(11) SIMAP similar genes for SEMA5B Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for SEMA5B Gene

Variants for SEMA5B Gene

Sequence variations from dbSNP and Humsavar for SEMA5B Gene

SNP ID	Clin	Chr 03 pos	Sequence Context	Type
VAR_037196	A breast cancer sample
rs2276774	-	122,927,981(-)	GACTA(C/T)TGAGA	nc-transcript-variant, reference, missense
VAR_037198	A breast cancer sample
rs2276781	-	122,913,589(-)	GGGCA(C/T)GCAGT	nc-transcript-variant, reference, missense
rs2276782	-	122,913,049(-)	GGAGG(A/C/T)CCTCC	nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for SEMA5B Gene

Variant ID	Type	Subtype	PubMed ID
nsv829706	CNV	Gain	17160897
nsv877393	CNV	Gain	21882294
esv998863	CNV	Insertion	20482838
nsv517695	CNV	Loss	19592680
nsv460835	CNV	Gain	19166990
nsv460836	CNV	Loss	19166990
esv2678374	CNV	Deletion	23128226

Variation tolerance for SEMA5B Gene

Residual Variation Intolerance Score: 71.8% of all genes are more intolerant (likely to be disease-causing)

Gene Damage Index Score: 10.22; 90.50% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for SEMA5B Gene

Disorders for SEMA5B Gene

Relevant External Links for SEMA5B

Genetic Association Database (GAD): SEMA5B
Human Genome Epidemiology (HuGE) Navigator: SEMA5B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:: SEMA5B

No disorders were found for SEMA5B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SEMA5B Gene

Publications for SEMA5B Gene

Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. (PMID: 21642993) Wu C. … Lin D. (Nat. Genet. 2011) ³ ⁴⁸ ⁶⁷
Semaphorin 5B mediates synapse elimination in hippocampal neurons. (PMID: 19463192) O'Connor T.P. … Bamji S.X. (Neural Dev 2009) ³ ²³
A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis. (PMID: 8817451) Adams R.H. … PA1schel A.W. (Mech. Dev. 1996) ² ³
Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy. (PMID: 26460568) Johnson-Kerner B.L. … Wichterle H. (PLoS ONE 2015) ³
A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) ³