Aliases for SEMA3B Gene
External Ids for SEMA3B Gene
Previous HGNC Symbols for SEMA3B Gene
Previous GeneCards Identifiers for SEMA3B Gene
The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
GeneCards Summary for SEMA3B Gene
SEMA3B (Semaphorin 3B) is a Protein Coding gene. Diseases associated with SEMA3B include Phencyclidine Abuse and Lung Cancer. Among its related pathways are Neuroscience and Axon guidance. Gene Ontology (GO) annotations related to this gene include receptor activity. An important paralog of this gene is SEMA3A.
UniProtKB/Swiss-Prot for SEMA3B Gene
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.