Aliases for SEMA3B Gene
External Ids for SEMA3B Gene
Previous HGNC Symbols for SEMA3B Gene
Previous GeneCards Identifiers for SEMA3B Gene
The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
GeneCards Summary for SEMA3B Gene
SEMA3B (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3B) is a Protein Coding gene. Diseases associated with SEMA3B include phencyclidine abuse and renal cell carcinoma. Among its related pathways are Axon guidance and Neuroscience. GO annotations related to this gene include receptor activity.
UniProtKB/Swiss-Prot for SEMA3B Gene
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.