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Aliases for SELV Gene

Aliases for SELV Gene

  • Selenoprotein V 3
  • SelV 4

External Ids for SELV Gene

Summaries for SELV Gene

Entrez Gene Summary for SELV Gene

  • This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]

GeneCards Summary for SELV Gene

SELV (Selenoprotein V) is a Protein Coding gene. Diseases associated with SELV include staphyloenterotoxemia. Among its related pathways are Selenium Metabolism and Selenoproteins and Selenium Pathway. GO annotations related to this gene include selenium binding. An important paralog of this gene is SEPW1.

UniProtKB/Swiss-Prot for SELV Gene

  • May be involved in a redox-related process.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SELV Gene

Genomics for SELV Gene

Genomic Location for SELV Gene

Start:
39,515,113 bp from pter
End:
39,520,686 bp from pter
Size:
5,574 bases
Orientation:
Plus strand

Genomic View for SELV Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SELV Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SELV Gene

Regulatory Elements for SELV Gene

Proteins for SELV Gene

  • Protein details for SELV Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P59797-SELV_HUMAN
    Recommended name:
    Selenoprotein V
    Protein Accession:
    P59797
    Secondary Accessions:
    • Q17RG5

    Protein attributes for SELV Gene

    Size:
    346 amino acids
    Molecular mass:
    36800 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SELV Gene

Proteomics data for SELV Gene at MOPED

Post-translational modifications for SELV Gene

No Post-translational modifications

Other Protein References for SELV Gene

No data available for DME Specific Peptides for SELV Gene

Domains for SELV Gene

Protein Domains for SELV Gene

UniProtKB/Swiss-Prot:

SELV_HUMAN
Family:
  • Belongs to the SelWTH family.:
    • P59797
genes like me logo Genes that share domains with SELV: view

No data available for Gene Families for SELV Gene

Function for SELV Gene

Molecular function for SELV Gene

UniProtKB/Swiss-Prot Function: May be involved in a redox-related process.

Gene Ontology (GO) - Molecular Function for SELV Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0008430 selenium binding IEA --
genes like me logo Genes that share ontologies with SELV: view

Phenotypes for SELV Gene

genes like me logo Genes that share phenotypes with SELV: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SELV Gene

Localization for SELV Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SELV Gene COMPARTMENTS Subcellular localization image for SELV gene
Compartment Confidence
mitochondrion 2
cytosol 1
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for SELV Gene

Pathways for SELV Gene

genes like me logo Genes that share pathways with SELV: view

Pathways by source for SELV Gene

2 BioSystems pathways for SELV Gene

Gene Ontology (GO) - Biological Process for SELV Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045454 cell redox homeostasis IEA --
genes like me logo Genes that share ontologies with SELV: view

Transcripts for SELV Gene

mRNA/cDNA for SELV Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SELV Gene

Selenoprotein V:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SELV Gene

No ASD Table

Relevant External Links for SELV Gene

GeneLoc Exon Structure for
SELV

Expression for SELV Gene

mRNA expression in normal human tissues for SELV Gene

mRNA differential expression in normal tissues according to GTEx for SELV Gene

This gene is overexpressed in Testis (37.2) and Thyroid (6.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SELV Gene

SOURCE GeneReport for Unigene cluster for SELV Gene Hs.319284

mRNA Expression by UniProt/SwissProt for SELV Gene

P59797-SELV_HUMAN
Tissue specificity: Testis specific.
genes like me logo Genes that share expressions with SELV: view

Orthologs for SELV Gene

This gene was present in the common ancestor of chordates.

Orthologs for SELV Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SELV 36
  • 99.04 (n)
  • 99.13 (a)
SELV 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SELV 37
  • 43 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 16 (a)
OneToOne
LOC102151122 36
  • 72 (n)
  • 59.56 (a)
mouse
(Mus musculus)
Mammalia BC089491 36
  • 59.3 (n)
  • 48.18 (a)
BC089491 16
BC089491 37
  • 43 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Selv 36
  • 60.34 (n)
  • 48.87 (a)
zebrafish
(Danio rerio)
Actinopterygii sepw1 37
  • 47 (a)
OneToMany
Species with no ortholog for SELV:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SELV Gene

ENSEMBL:
Gene Tree for SELV (if available)
TreeFam:
Gene Tree for SELV (if available)

Paralogs for SELV Gene

Paralogs for SELV Gene

Selected SIMAP similar genes for SELV Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with SELV: view

Variants for SELV Gene

Sequence variations from dbSNP and Humsavar for SELV Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs4802034 -- 39,519,043(+) GAGAC(C/T)TGTGT intron-variant
rs4803252 -- 39,513,540(+) ttacc(A/T)tgttg upstream-variant-2KB
rs4803253 -- 39,513,662(+) ttttt(A/T)ttttA upstream-variant-2KB
rs4803254 -- 39,514,000(+) GCTTA(C/T)AAAAA upstream-variant-2KB
rs5828040 -- 39,519,986(+) AAAAA(-/A)GGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SELV Gene

Variant ID Type Subtype PubMed ID
dgv3863n71 CNV Loss 21882294
dgv3864n71 CNV Loss 21882294
nsv522811 CNV Loss 19592680

Relevant External Links for SELV Gene

HapMap Linkage Disequilibrium report
SELV

Disorders for SELV Gene

(1) MalaCards Diseases for SELV Gene

Search for SELV Gene in MalaCards »

(1) University of Copenhagen DISEASES for SELV Gene

Relevant External Links for SELV

Human Genome Epidemiology (HuGE) Navigator
SELV
genes like me logo Genes that share disorders with SELV: view

No data available for UniProtKB/Swiss-Prot for SELV Gene

Publications for SELV Gene

  1. Characterization of mammalian selenoproteomes. (PMID: 12775843) Kryukov G.V. … Gladyshev V.N. (Science 2003) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. (PMID: 21048031) Casabonne D. … de Sanjose S. (Haematologica 2011) 3
  4. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PMID: 22990118) Woods N.T. … Monteiro A.N. (Sci Signal 2012) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for SELV Gene

Sources for SELV Gene

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