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SELT Gene

protein-coding   GIFtS: 47
GCID: GC03P150321

Selenoprotein T


  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Selenoprotein T2
SelT3

External Ids:    Entrez Gene: 517142   Ensembl: ENSG000001988437   OMIM: 6079125   UniProtKB: P623413   

Export aliases for SELT gene to outside databases

Previous GC identifers: GC03U900030 GC03P151602 GC03P151641 GC03P151803


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SELT Gene:
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The
selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of
selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for
the recognition of UGA as a Sec codon rather than as a stop signal. (provided by RefSeq, Jul 2008)

GeneCards Summary for SELT Gene:
SELT is a protein-coding gene. Diseases associated with SELT include malaria. GO annotations related to this gene include selenium binding.

Gene Wiki entry for SELT Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the SELT gene promoter:
         AhR   RFX1   Arnt   Evi-1   YY1   GATA-1   MZF-1   S8   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSELT promoter sequence
   Search Chromatin IP Primers for SELT

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SELT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.1   Ensembl cytogenetic band:  3q25.1   

SELT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SELT gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P150321:  view genomic region     (about GC identifiers)

Start:
150,320,662 bp from pter      End:
150,348,234 bp from pter
Size:
27,573 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SELT_HUMAN, P62341 (See protein sequence)
Recommended Name: Selenoprotein T precursor  
Size: 195 amino acids; 22324 Da
Sequence caution: Sequence=AAD20063.1; Type=Erroneous termination; Positions=49; Note=Translated as Sec;
Sequence=AAF13696.1; Type=Frameshift; Positions=27; Sequence=AAQ88462.1; Type=Erroneous termination;
Positions=49; Note=Translated as Sec; Sequence=AAQ88463.1; Type=Erroneous termination; Positions=49;
Note=Translated as Sec;
Secondary accessions: O95904 Q8IY80 Q9CZ45 Q9NZJ3

Explore the universe of human proteins at neXtProt for SELT: NX_P62341

Explore proteomics data for SELT at MOPED

Post-translational modifications: 

  • May contain a selenide-sulfide bond between Cys-46 and Sec-49. This bond is speculated to serve as redox-active
    pair (By similarity)1
  • Ubiquitination2 at Lys32
  • Modification sites at PhosphoSitePlus

  • See SELT Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057359.2  
    ENSEMBL proteins: 
     ENSP00000417762   ENSP00000418910   ENSP00000417932   ENSP00000417703   ENSP00000420390  

    SELT Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for SELT
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    Novus Biologicals SELT Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SELT

    SELT Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    OriGene Custom Antibody Services for SELT
    Novus Biologicals SELT Antibody
    Abcam antibodies for SELT
    Cloud-Clone Corp. Antibodies for SELT
    ThermoFisher Antibodies for SELT
    LSBio Antibodies in human, mouse, rat for SELT

    SELT Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SELT
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SELT
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SELT
    Cloud-Clone Corp. CLIAs for SELT


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR019389 Selenoprotein_T
     IPR011893 Selenoprotein_Rdx-typ
     IPR012336 Thioredoxin-like_fold

    Graphical View of Domain Structure for InterPro Entry P62341

    ProtoNet protein and cluster: P62341

    UniProtKB/Swiss-Prot: SELT_HUMAN, P62341
    Similarity: Belongs to the SelWTH family. SELT subfamily


    SELT for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008430selenium binding NAS10567350
         
    SELT for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SELT:
     Increased gamma-H2AX phosphory 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for 2810407C02Rik):
     endocrine/exocrine gland  homeostasis/metabolism 

    SELT for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SELT
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SELT

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SELT
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SELT

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SELT using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SELT (see all 76):
    hsa-miR-548j hsa-miR-607 hsa-miR-3194-5p hsa-miR-188-5p hsa-miR-3142 hsa-miR-1244 hsa-miR-3122 hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidSELT 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SELT
    Search Predesigned siRNA for gene silencing in human, mouse, rat SELT

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SELT

    Clone
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    OriGene clones in human, mouse for SELT (see all 6)
    OriGene ORF clones in mouse, rat for SELT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SELT (NM_016275)
    Sino Biological Human cDNA Clone for SELT
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SELT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SELT

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SELT
    Browse ESI BIO Cell Lines and PureStem Progenitors for SELT 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SELT


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum2
    plasma membrane2
    extracellular1
    golgi apparatus1
    nucleus1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SELT About    
    See pathways by source

    SuperPathContained pathways About
    1Selenium Pathway
    Selenium Pathway
    2Selenium Metabolism and Selenoproteins
    Selenium Metabolism and Selenoproteins


    2 BioSystems Pathways for SELT
        Selenium Metabolism and Selenoproteins
    Selenium Pathway



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SELT
    Interactions:

        Search GeneGlobe Interaction Network for SELT

    4 Interacting proteins for SELT (P623412, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HBBP688713I2D: score=4 
    ADD1P356113I2D: score=3 
    --Q144853, 2MINT-64173 I2D: score=1 
    --Q144853, 2MINT-64173 I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001514selenocysteine incorporation NAS10567350
    GO:0045454cell redox homeostasis IEA--

    SELT for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SELT

    1 HMDB Compound for SELT    About this table
    CompoundSynonyms CAS #PubMed Ids
    Selenocysteine(2R)-2-amino-3-selanylpropanoate (see all 8)3614-08-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SELT gene: 
    NM_016275.3  

    Unigene Cluster for SELT:

    Selenoprotein T
    Hs.369052  [show with all ESTs]
    Unigene Representative Sequence: NM_016275
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000480740 ENST00000471696(uc021xfp.1) ENST00000477889 ENST00000492132
    ENST00000485923 ENST00000466234
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SELT using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SELT (see all 76):
    hsa-miR-548j hsa-miR-607 hsa-miR-3194-5p hsa-miR-188-5p hsa-miR-3142 hsa-miR-1244 hsa-miR-3122 hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidSELT 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SELT
    Search Predesigned siRNA for gene silencing in human, mouse, rat SELT
    Clone
    Products:
         
    OriGene clones in human, mouse for SELT (see all 6)
    OriGene ORF clones in mouse, rat for SELT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SELT (NM_016275)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SELT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SELT
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SELT
    OriGene qSTAR qPCR primer pairs in human, mouse for SELT
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SELT
      QuantiTect SYBR Green Assays in human, mouse, rat SELT
      QuantiFast Probe-based Assays in human, mouse, rat SELT

    Additional mRNA sequence: 

    AF131856.1 AF195141.1 AK075006.1 AK300315.1 AY358095.1 AY358096.1 BC006012.1 BC008411.1 
    BC009556.1 BC009611.1 BC026350.1 BC036738.1 BC071699.1 CR457154.1 

    23 DOTS entries:

    DT.100810462  DT.100037775  DT.92040477  DT.100883615  DT.102821417  DT.100682734  DT.92467113  DT.100883616 
    DT.100883617  DT.75150932  DT.96085200  DT.100810461  DT.92467060  DT.120912441  DT.92467086  DT.92467082 
    DT.100883611  DT.120912549  DT.95282508  DT.95282575  DT.95282629  DT.120912661  DT.91900177 

    Selected AceView cDNA sequences (see all 757):

    BQ879036 AA251673 BX385182 AI983988 BE907702 N53125 BU542742 AA995898 
    AA746601 AI084323 BQ424600 BM665988 AI338148 BC036738 BQ430024 BQ430293 
    AI828939 BQ045293 BQ919029 AA587928 BE781008 BU149903 BE907973 BI712402 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SELT    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8
    SP1:                          -     -                       -                           
    SP2:                          -                             -                           
    SP3:                          -     -                                                   
    SP4:                                -                       -                           



    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SELT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTTGACCAA
    SELT Expression
    About this image

    SELT Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SELT Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.369052

    UniProtKB/Swiss-Prot: SELT_HUMAN, P62341
    Tissue specificity: Ubiquitous

        Custom PCR Arrays for SELT
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    QuantiTect SYBR Green Assays in human, mouse, rat SELT
    QuantiFast Probe-based Assays in human, mouse, rat SELT
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SELT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SELT gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia 2810407C02Rik5
    Selt1
    RIKEN cDNA 2810407C02 gene5
    selenoprotein T1
    95.21(n)1
    99.49(a)1
      3 (28.61 cM)5
    692271  NM_001040396.21  NP_001035486.21 
     585766365 
    chicken
    (Gallus gallus)
    Aves SELT1 selenoprotein T 86.96(n)
    91.85(a)
      425041  NM_001006557.3  NP_001006557.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    97(a)
    1 ↔ 1
    3(18342604-18347621)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC043894.12   -- 85.19(n)    BC043894.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sept1a2 selenoprotein T, 1a 78.43(n)   352919  AY221264.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG38871 CG3887 53.67(n)
    41.24(a)
      33725  NM_135053.4  NP_608897.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C35C5.36
    F28H7.46
    Protein F28H7.4 (F28H7.4) mRNA, complete cds
    24(a)
    23(a)
    many → 1
    many → 1
    X(11545116-11546495) WBGene00007955
    V(10746548-10747337) WBGene00009238


    ENSEMBL Gene Tree for SELT (if available)
    TreeFam Gene Tree for SELT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SELT gene

    SELT for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SELT
    PGOHUM00000235388 PGOHUM00000236375


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SELT (see all 486)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1918215521,2
    --150319147(+) TGGGTA/CGAGGC 1 -- us2k10--------
    rs1833728691,2
    --150319168(+) GGGTCC/TAAGAA 1 -- us2k10--------
    rs1422549921,2
    --150319357(+) ATGACA/GACATA 1 -- us2k10--------
    rs1460768251,2
    C--150319420(+) ACAACA/GTTGAA 1 -- us2k10--------
    rs1388501061,2
    C--150319436(+) TTGGAC/TACTCT 1 -- us2k10--------
    rs1492853131,2
    --150319513(+) TCGGAC/TCTTGT 1 -- us2k10--------
    rs18187871,2
    C--150319544(+) ATTCAC/TACAAA 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs119279981,2
    C,F,H--150319582(+) ctataG/Cgacaa 1 -- us2k13Minor allele frequency- C:0.40WA NA CSA 5
    rs1852893741,2
    --150319622(+) CCCCTC/TACCCC 1 -- us2k10--------
    rs18187881,2
    C,F,A--150319684(+) taatcC/Tcgctc 1 -- us2k15Minor allele frequency- T:0.33NA CSA 9

    HapMap Linkage Disequilibrium report for SELT (150320662 - 150348234 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SELT: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SELT
    DNA2.0 Custom Variant and Variant Library Synthesis for SELT

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607912    OMIM disorders: --

    1 disease for SELT:    
    About MalaCards
    malaria


    SELT for disorders           About GeneDecksing


    Export disorders for SELT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SELT gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with SELT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    3. New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements. (PubMed id 10567350)1, 2 Kryukov G.V.... Gladyshev V.N. (J. Biol. Chem. 1999)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. The PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human I^-cells and its targeted inactivation impairs glucose tolerance. (PubMed id 23913443)1 Prevost G....Anouar Y. (Endocrinology 2013)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    8. SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family. (PubMed id 17503775)1 Dikiy A....Gladyshev V.N. (Biochemistry 2007)
    9. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
    10. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (DNA Res. 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51714 AceView: SELT Ensembl:ENSG00000198843 euGenes: HUgn51714

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SELT gene:
    Search GeneIP for patents involving SELT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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