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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SELT Gene

protein-coding   GIFtS: 45
GCID: GC03P150321

SELT
  Search for SELT
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SELT    

Aliases
for SELT gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Selenoprotein T2
SelT3

External Ids:    Entrez Gene: 517142   Ensembl: ENSG000001988437   OMIM: 6079125   UniProtKB: P623413   

Export aliases for SELT gene to outside databases

Previous GC identifers: GC03U900030 GC03P151602 GC03P151641 GC03P151803


Summaries
for SELT gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SELT:
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine
is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a
common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec
codon rather than as a stop signal. (provided by RefSeq, Jul 2008)

Gene Wiki entry for SELT


Genomic Views
for SELT gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SELT gene promoter:
         AhR   RFX1   Arnt   Evi-1   YY1   GATA-1   MZF-1   S8   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SELT promoter sequence
   Search SABiosciences Chromatin IP Primers for SELT

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SELT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.1   Ensembl cytogenetic band:  3q25.1   

SELT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SELT gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P150321:  view genomic region     (about GC identifiers)

Start:
 150,320,662 bp from pter      End:
 150,348,234 bp from pter
Size:
 27,573 bases      Orientation:
 plus strand

Proteins
for SELT gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SELT_HUMAN, P62341 (See protein sequence)
Recommended Name: Selenoprotein T precursor  
Size: 195 amino acids; 22324 Da
Sequence caution: Sequence=AAD20063.1; Type=Erroneous termination; Positions=49; Note=Translated as Sec;
Sequence=AAF13696.1; Type=Frameshift; Positions=27; Sequence=AAQ88462.1; Type=Erroneous termination; Positions=49;
Note=Translated as Sec; Sequence=AAQ88463.1; Type=Erroneous termination; Positions=49; Note=Translated as Sec;
Secondary accessions: O95904 Q8IY80 Q9CZ45 Q9NZJ3

Explore the universe of human proteins at neXtProt for SELT: NX_P62341

Post-translational modifications:

  • May contain a selenide-sulfide bond between Cys-46 and Sec-49. This bond is speculated to serve as redox-active pair
    • (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P62341

    • SELT Protein expression data from MOPED and PaxDb:    About this image 
    SELT Protein Expression
    REFSEQ proteins: NP_057359.2  
    ENSEMBL proteins: 
     ENSP00000417762   ENSP00000418910   ENSP00000417932   ENSP00000417703   ENSP00000420390  

    Human Recombinant Protein Products for SELT: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: SELT
    OriGene Custom Protein Services for SELT 
    GenScript Custom Purified and Recombinant Proteins Services for SELT
    Novus Biologicals SELT Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SELT


    SELT Antibody Products: 
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    Novus Biologicals SELT Antibody
    Abcam antibodies for SELT 
    Uscn Antibodies for SELT
    ThermoFisher Antibodies for SELT

    Assay Products for SELT: 
    Browse Kits and Assays available from EMD Millipore
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    Uscn ELISAs and CLIAs for SELT

    Protein Domains /
    Families
    for SELT gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SELT for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR019389 Selenoprotein_T
     IPR011893 Selenoprotein_Rdx-typ
     IPR012336 Thioredoxin-like_fold

    Graphical View of Domain Structure for InterPro Entry P62341

    ProtoNet protein and cluster: P62341

    UniProtKB/Swiss-Prot: SELT_HUMAN, P62341
    Similarity: Belongs to the SelWTH family. SELT subfamily


    Function
    for SELT gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008430selenium binding NAS10567350
         
    SELT for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SELT:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SELT 

    miRNA
    Products:            		 OriGene 3'-UTR Clone: SELT
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SELT
    8/76 QIAGEN miScript miRNA Assays for microRNAs that regulate SELT (see all 76):
    hsa-miR-548j hsa-miR-607 hsa-miR-3194-5p hsa-miR-188-5p hsa-miR-3142 hsa-miR-1244 hsa-miR-3122 hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmid: SELT 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SELT (see all 4)
    OriGene shRNA RFP: SELT
    OriGene siRNA: SELT
    Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SELT
    Sirion Biotech Custom design and validation of potent shRNA sequences against SELT 

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for SELT
    Sirion Biotech Customized adenovirus for overexpression of SELT 
    Sirion Biotech Customized adenovirus for potent knockdown of SELT

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SELT (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SELT
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    GenScript: all cDNA clones in your preferred vector: SELT (NM_016275)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SELT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SELT 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for SELT
    Search LifeMap BioReagents cell lines for SELT
    Sirion Biotech Customized stable knockdown cell line services for SELT 
    Sirion Biotech Customized inducible knockdown cell line services for SELT
    Sirion Biotech Customized stable overexpressing cell line services for SELT
    Sirion Biotech Customized inducible overexpressing cell line services for SELT

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SELT


    Pathways & Interactions
    for SELT gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Selenium Metabolism and Selenoproteins
    		Selenium Metabolism and Selenoproteins1.00
    2Selenium Pathway
    		Selenium Pathway1.00


    2 BioSystems Pathways for SELT 
        Selenium Metabolism and Selenoproteins
    Selenium Pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SELT

    4 Interacting proteins for SELT (P623412, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HBBP688713I2D: score=4 
    ADD1P356113I2D: score=3 
    --Q144853, 2MINT-64173 I2D: score=1 
    --Q144853, 2MINT-64173 I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001514selenocysteine incorporation NAS10567350
    GO:0045454cell redox homeostasis IEA--

    SELT for ontologies           About GeneDecksing



    Drugs & Compounds
    for SELT gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SELT

    1 HMDB Compound for SELT    About this table
    CompoundSynonyms CAS #PubMed Ids
    Selenocysteine(2R)-2-amino-3-selanylpropanoate (see all 8)3614-08-2--
    Search CenterWatch for drugs/clinical trials and news about SELT 

    Transcripts
    for SELT gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SELT gene: 
    NM_016275.3  

    Unigene Cluster for SELT:

    Selenoprotein T
    Hs.369052  [show with all ESTs]
    Unigene Representative Sequence: NM_016275
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000480740 ENST00000471696(uc021xfp.1) ENST00000477889 ENST00000492132
    ENST00000485923 ENST00000466234

    miRNA
    Products:             		 OriGene 3'-UTR Clone: SELT
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SELT
    8/76 QIAGEN miScript miRNA Assays for microRNAs that regulate SELT (see all 76):
    hsa-miR-548j hsa-miR-607 hsa-miR-3194-5p hsa-miR-188-5p hsa-miR-3142 hsa-miR-1244 hsa-miR-3122 hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmid: SELT 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SELT (see all 4)
    OriGene shRNA RFP: SELT
    OriGene siRNA: SELT
    Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SELT
    Sirion Biotech Custom design and validation of potent shRNA sequences against SELT 
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SELT (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SELT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SELT (NM_016275)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SELT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SELT 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SELT
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SELT
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SELT

    Additional cDNA sequence: 

    AF131856.1 AF195141.1 AK075006.1 AK300315.1 AY358095.1 AY358096.1 BC006012.1 BC008411.1 
    BC009556.1 BC009611.1 BC026350.1 BC036738.1 BC071699.1 CR457154.1 

    23 DOTS entries:

    DT.100810462  DT.100037775  DT.92040477  DT.100883615  DT.102821417  DT.100682734  DT.92467113  DT.100883616 
    DT.100883617  DT.75150932  DT.96085200  DT.100810461  DT.92467060  DT.120912441  DT.92467086  DT.92467082 
    DT.100883611  DT.120912549  DT.95282508  DT.95282575  DT.95282629  DT.120912661  DT.91900177 

    24/757 AceView cDNA sequences (see all 757):

    CF527976 BC071699 AA906085 AA694574 BF444980 BU184581 AW664798 AI285275 
    BU195565 CB243570 BQ933520 CB148669 AA505593 BQ225883 BM555486 N40334 
    BE907061 Z40284 AA587932 N50754 AA815111 T35247 CR607479 AI685545 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SELT    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8
    SP1:                          -     -                       -                           
    SP2:                          -                             -                           
    SP3:                          -     -                                                   
    SP4:                                -                       -                           



    Expression
    for SELT gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SELT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCTTGACCAA
    SELT Expression
    About this image

    SELT expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Intermediate limb mesenchymal cells (ILM cells) (Primary Cell)Bone, Cartilage, Limb
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SELT Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SELT

    SOURCE GeneReport for Unigene cluster: Hs.369052

    UniProtKB/Swiss-Prot: SELT_HUMAN, P62341
    Tissue specificity: Ubiquitous

        SABiosciences Custom PCR Arrays for SELT
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SELT

    Orthologs
    for SELT gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SELT gene from 9/24 species (see all 24)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia 2810407C02Rik1 , 5 RIKEN cDNA 2810407C02 gene1, 5 95.21(n)1
    99.49(a)1    		   3 (28.61 cM)5
    692271  NM_001040396.21  NP_001035486.21 
     585766365 
    chicken
    (Gallus gallus)    		 Aves SELT1 selenoprotein T 86.17(n)
    90.43(a)    		   425041  NM_001006557.3  NP_001006557.3 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 97(a)
    		 1 ↔ 1
    		 3(18342635-18347607)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BC043894.12   -- 85.19(n)    BC043894.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii sept1a2 selenoprotein T, 1a 78.43(n)   352919  AY221264.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG38871 CG3887 53.8(n)
    41.85(a)    		   33725  NM_135053.3  NP_608897.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea F28H7.46
    C35C5.36
    		 Putative selT-like protein C35C5.3
    		 24(a)
    23(a)
    		 many → 1
    many → 1
    		 V(10746528-10747317)
    X(11545050-11546431)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SELT6
    AT5G586406
    		 Selenoprotein, Rdx type
    		 18(a)
    16(a)
    		 many → 1
    many → 1
    		 3(17428443-17429623)
    5(23697841-23699767)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 selT-like protein precursor, putative, expressed
    		 16(a)
    14(a)
    		 many → 1
    many → 1
    		 1(35608571-35612060)
    5(22870089-22873279)


    ENSEMBL Gene Tree for SELT (if available)
    TreeFam Gene Tree for SELT (if available) 

    Paralogs
    for SELT gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SELT gene

    SELT for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SELT
    PGOHUM00000235388 PGOHUM00000236375


    Genomic Variants
    for SELT gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/396 NCBI SNPs in SELT are shown (see all 396)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1918215521,2
    		--150319147(+) TGGGTA/CGAGGC 1 -- us2k10--------
    rs1833728691,2
    		--150319168(+) GGGTCC/TAAGAA 1 -- us2k10--------
    rs1422549921,2
    		--150319357(+) ATGACA/GACATA 1 -- us2k10--------
    rs1460768251,2
    		--150319420(+) ACAACA/GTTGAA 1 -- us2k10--------
    rs1388501061,2
    		--150319436(+) TTGGAC/TACTCT 1 -- us2k10--------
    rs1492853131,2
    		--150319513(+) TCGGAC/TCTTGT 1 -- us2k10--------
    rs18187871,2
    		C--150319544(+) ATTCAC/TACAAA 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs119279981,2
    		C,F,H--150319582(+) ctataG/Cgacaa 1 -- us2k13Minor allele frequency- C:0.40WA NA CSA 5
    rs1852893741,2
    		--150319622(+) CCCCTC/TACCCC 1 -- us2k10--------
    rs18187881,2
    		C,F,A--150319684(+) TAATCC/TCGCTC 1 -- us2k15Minor allele frequency- T:0.33NA CSA 9

    HapMap Linkage Disequilibrium report for SELT (150320662 - 150348234 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SELT: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SELT
    DNA2.0 Custom Variant and Variant Library Synthesis for SELT

    Disorders / Diseases
    for SELT gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SELT for disorders           About MalaCards

    SELT for disorders           About GeneDecksing

    OMIM gene information: 607912    OMIM disorders: --


    Export disorders for SELT gene to outside databases

    Publications
    for SELT gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SELT gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with SELT)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    3. New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements. (PubMed id 10567350)1, 2 Kryukov G.V.... Gladyshev V.N. (1999)
    4. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    6. SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family. (PubMed id 17503775)1 Dikiy A....Gladyshev V.N. (2007)
    7. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
    8. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (2005)
    9. Characterization of mammalian selenoproteomes. (PubMed id 12775843)1 Kryukov G.V.... Gladyshev V.N. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for SELT gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing SELT gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51714 AceView: SELT Ensembl:ENSG00000198843 euGenes: HUgn51714

    Other Databases showing SELT gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SELT gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    		   --

    Intellectual Property
    for SELT gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SELT gene:
    Search GeneIP for patents involving SELT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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