External Ids for SELM Gene
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures. [provided by RefSeq, Jul 2008]
GeneCards Summary for SELM Gene
SELM (Selenoprotein M) is a Protein Coding gene. Diseases associated with SELM include staphyloenterotoxemia. Among its related pathways are Selenium Metabolism and Selenoproteins and Selenium Pathway.
UniProtKB/Swiss-Prot for SELM Gene
May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.