Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SEL1L2 Gene

protein-coding   GIFtS: 41
GCID: GC20M013779

Sel-1 Suppressor Of Lin-12-Like 2 (C. Elegans)

(Previous name: chromosome 20 open reading frame 50)
(Previous symbol: C20orf50)
  Search for SEL1L2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Sel-1 Suppressor Of Lin-12-Like 2 (C. Elegans)1 2     Protein Sel-1 Homolog 22
C20orf501 2 3     sel-1L22
Suppressor Of Lin-12-Like Protein 22 3     Sel-1L23
Chromosome 20 Open Reading Frame 501     

External Ids:    HGNC: 158971   Entrez Gene: 803432   Ensembl: ENSG000001012517   OMIM: 6142895   UniProtKB: Q5TEA63   

Export aliases for SEL1L2 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for SEL1L2 Gene:
SEL1L2 (sel-1 suppressor of lin-12-like 2 (C. elegans)) is a protein-coding gene. An important paralog of this gene is SEL1L3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000020.11  NT_011387.9  NC_018931.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SEL1L2 gene promoter:
         MIF-1   POU3F2   CBF-C   RORalpha2   CBF-A   CBF-B   CP1C   CP1A   MRF-2   CBF(2)   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SEL1L2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SEL1L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p12.1   Ensembl cytogenetic band:  20p12.1   HGNC cytogenetic band: 20p12.1

SEL1L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEL1L2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M013779:  view genomic region     (about GC identifiers)

Start:
13,829,893 bp from pter      End:
13,977,089 bp from pter
Size:
147,197 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SE1L2_HUMAN, Q5TEA6 (See protein sequence)
Recommended Name: Protein sel-1 homolog 2 precursor  
Size: 688 amino acids; 77964 Da
Sequence caution: Sequence=CAI22078.1; Type=Erroneous gene model prediction; Sequence=CAI22983.1; Type=Erroneous
gene model prediction;
Secondary accessions: B4DXX5
Alternative splicing: 2 isoforms:  Q5TEA6-1   Q5TEA6-2   

Explore the universe of human proteins at neXtProt for SEL1L2: NX_Q5TEA6

Explore proteomics data for SEL1L2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys101
  • Glycosylation2 at Asn34
  • Modification sites at PhosphoSitePlus

  • See SEL1L2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001258468.1  
    ENSEMBL proteins: 
     ENSP00000418040   ENSP00000284951   ENSP00000394598   ENSP00000367312   ENSP00000420372  

    SEL1L2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SEL1L2
    GenScript Custom Purified and Recombinant Proteins Services for SEL1L2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SEL1L2

    SEL1L2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SEL1L2
    Search for Antibodies for SEL1L2 at Abcam
    Cloud-Clone Corp. Antibodies for SEL1L2
    Search ThermoFisher Antibodies for SEL1L2
    LSBio Antibodies in human, mouse, rat for SEL1L2

    SEL1L2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SEL1L2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SEL1L2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SEL1L2
    Cloud-Clone Corp. CLIAs for SEL1L2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR006597 Sel1-like

    Graphical View of Domain Structure for InterPro Entry Q5TEA6

    ProtoNet protein and cluster: Q5TEA6

    UniProtKB/Swiss-Prot: SE1L2_HUMAN, Q5TEA6
    Similarity: Belongs to the sel-1 family
    Similarity: Contains 11 Sel1-like repeats


    SEL1L2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SEL1L2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SEL1L2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SEL1L2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SEL1L2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SEL1L2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SEL1L2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SEL1L2
    Predesigned siRNA for gene silencing in human, mouse, rat SEL1L2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SEL1L2

    Clone
    Products:
         
    OriGene clones in human, mouse for SEL1L2 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SEL1L2 (NM_025229)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SEL1L2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SEL1L2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SEL1L2
    Browse ESI BIO Cell Lines and PureStem Progenitors for SEL1L2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEL1L2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SE1L2_HUMAN, Q5TEA6: Membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum3
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    SEL1L2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SEL1L2
    Interactions:

        Search GeneGlobe Interaction Network for SEL1L2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for SEL1L2 (ENSP000002849514) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    ATP6V0BENSP000002360674STRING: ENSP00000236067
    NPLOC4ENSP000003314874STRING: ENSP00000331487
    UBE2G2ENSP000003383484STRING: ENSP00000338348
    PPA1ENSP000003623294STRING: ENSP00000362329
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SEL1L2 (SE1L2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SEL1L2 gene (2 alternative transcripts): 
    NM_025229.1  NM_001271539.1  

    Unigene Cluster for SEL1L2:

    Sel-1 suppressor of lin-12-like 2 (C. elegans)
    Hs.590879  [show with all ESTs]
    Unigene Representative Sequence: BC035741
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000482196 ENST00000475649 ENST00000284951 ENST00000423870(uc010gcf.3 uc002woq.4)
    ENST00000378072(uc010zrl.2) ENST00000486903(uc002wor.3) ENST00000492548
    ENST00000476952 ENST00000473203 ENST00000495437 ENST00000477435
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SEL1L2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SEL1L2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SEL1L2
    Predesigned siRNA for gene silencing in human, mouse, rat SEL1L2
    Clone
    Products:
         
    OriGene clones in human, mouse for SEL1L2 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SEL1L2 (NM_025229)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SEL1L2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SEL1L2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SEL1L2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SEL1L2
      QuantiTect SYBR Green Assays in human, mouse, rat SEL1L2
      QuantiFast Probe-based Assays in human, mouse, rat SEL1L2

    Additional mRNA sequence: 

    AK302170.1 AL137678.1 BC035741.1 NR_073206.1 NR_073207.1 

    5 DOTS entries:

    DT.91722982  DT.120824197  DT.91661988  DT.91754114  DT.91661990 

    18 AceView cDNA sequences:

    BG214394 BC035741 BF509718 CD359317 AL137678 BM554202 BG217556 BG220573 
    BG188306 BG191061 BG184754 BG218395 BG204271 BG203754 BG219992 BG182541 
    BG216522 BG195560 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SEL1L2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAACTGGAAA
    SEL1L2 Expression
    About this image

    SEL1L2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SEL1L2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.590879
        Custom PCR Arrays for SEL1L2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SEL1L2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SEL1L2
    QuantiTect SYBR Green Assays in human, mouse, rat SEL1L2
    QuantiFast Probe-based Assays in human, mouse, rat SEL1L2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEL1L2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SEL1L2 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-24p1.66
    si:dkey-24p1.6
    9(a)
    many ↔ many
    15(36997974-37028286) ENSDARG00000028784
    fruit fly
    (Drosophila melanogaster)
    Insecta Hrd36
    --
    25(a)
    1 → many
    3R(19580345-19584279)
    worm
    (Caenorhabditis elegans)
    Secernentea sel-16
    Protein SEL-1 (sel-1) mRNA, complete cds
    26(a)
    1 → many
    V(12560732-12563386) WBGene00004759
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SKT5(YBL061C)4 Activator of Chs3p (chitin synthase III), recruits more   --   2(107406-105316) 852218  NP_009492.1 
            Species with no ortholog for SEL1L2

    ENSEMBL Gene Tree for SEL1L2 (if available)
    TreeFam Gene Tree for SEL1L2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SEL1L2 gene
    SEL1L32  SEL1L2  
    1 SIMAP similar gene for SEL1L2 using alignment to 4 protein entries:     SE1L2_HUMAN (see all proteins):
    SEL1L

    SEL1L2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SEL1L2 (see all 2976)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1831302271,2
    --13829609(+) TTCAGA/GTACGA 3 -- ds50010--------
    rs60746501,2
    H--13829670(+) CATTCC/ATATAG 3 -- ds50014Minor allele frequency- A:0.00NS EA 420
    rs60791971,2
    H--13829733(+) GGGATC/ATGGAT 3 -- ds50014Minor allele frequency- A:0.00NS EA 420
    rs1463514021,2
    --13829780(+) AGTTTA/GTCTGT 3 -- ds50010--------
    rs732592741,2
    C,F--13829792(+) GGAGTC/GAGGAA 3 -- ds50012Minor allele frequency- G:0.13WA 120
    rs1131401231,2
    C,F--13829806(+) CAGTGC/TGTCCT 3 -- ds50012Minor allele frequency- T:0.04NA 122
    rs1397152431,2
    --13829835(+) GTTCTA/GACAAC 3 -- ds50010--------
    rs1146330471,2
    F--13829868(+) CATAAC/TGTGGG 3 -- ds50011Minor allele frequency- T:0.04WA 118
    rs1161249311,2
    C,F--13830025(+) CTGAGC/TGGGAA 3 -- ds50011Minor allele frequency- T:0.09WA 118
    rs1887564791,2
    --13830068(+) TGTTTA/GTTTAG 3 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for SEL1L2 (13829893 - 13977089 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SEL1L2 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2663578CNV Deletion23128226
    nsv513537CNV Insertion21212237
    nsv509762CNV Insertion20534489
    esv1588937CNV Insertion17803354
    nsv3296CNV Insertion18451855
    nsv3295CNV Insertion18451855
    esv1553078CNV Insertion17803354
    esv999444CNV Insertion20482838
    esv998605CNV Insertion20482838
    esv1485899CNV Insertion17803354

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SEL1L2
    DNA2.0 Custom Variant and Variant Library Synthesis for SEL1L2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 614289    OMIM disorders: --


    SEL1L2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SEL1L2
    Human Genome Epidemiology (HuGE) Navigator: SEL1L2 (1 document)

    Export disorders for SEL1L2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SEL1L2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SEL1L2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (Proteomics 2007)
    3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    4. Identification of a region within SEL1L protein required for tumour growth inhibition. (PubMed id 14729273)1 Cattaneo M....Biunno I. (Gene 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    7. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)2 Deloukas P....Rogers J. (Nature 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 80343 HGNC: 15897 AceView: C20orf50 Ensembl:ENSG00000101251 euGenes: HUgn80343
    ECgene: SEL1L2 H-InvDB: SEL1L2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SEL1L2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SEL1L2 gene:
    Search GeneIP for patents involving SEL1L2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SEL1L2  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SEL1L2  
     OriGene qSTAR qPCR primer pairs in human, mouse for SEL1L2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SEL1L2   OriGene Custom Protein Services for SEL1L2  

     
     
     Block miRNA regulation of human, mouse, rat SEL1L2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SEL1L2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SEL1L2 Predesigned siRNA for gene silencing in human, mouse, rat SEL1L2
     QuantiFast Probe-based Assays in human, mouse, rat SEL1L2 QuantiTect SYBR Green Assays in human, mouse, rat SEL1L2
     Custom PCR Arrays for SEL1L2 Search Chromatin IP Primers for SEL1L2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SEL1L2  Search GeneGlobe Interaction Network for SEL1L2
     Regulatory tfbs in SEL1L2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SEL1L2 GenScript cDNA clones with any tag delivered in your preferred vector for SEL1L2
     GenScript Custom Assay Services for SEL1L2 GenScript Custom overexpressing Cell Line Services for SEL1L2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SEL1L2 (SE1L2)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for SEL1L2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for SEL1L2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SEL1L2
     Antibodies for SEL1L2
     ELISAs for SEL1L2
     CLIAs for SEL1L2



     Browse ESI BIO Cell Lines and PureStem Progenitors for SEL1L2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEL1L2
     Browse SwitchGear 3'UTR luciferase reporter plasmids for SEL1L2
     Browse SwitchGear Promoter luciferase reporter plasmids for SEL1L2
     Search ThermoFisher Antibodies for SEL1L2
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SEL1L2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SEL1L2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SEL1L2
     LSBio Antibodies in human, mouse, rat for SEL1L2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SEL1L2 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4