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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEH1L Gene

protein-coding   GIFtS: 54
GCID: GC18P012947

SEH1-like (S. cerevisiae)

 Explore 3 diseases affiliated with
SEH1L via our new
 Human Malady Compendium 
Biological research products
for SEH1L
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
SEH1-Like (S. Cerevisiae)1 2     Nup107-160 Subcomplex Subunit SEH12 3
SEC13L1 2 3 5     SEC13-Like Protein2 3
SEH1A1 2     SEH13 5
SEH1B1 2     Nucleoporin SEH12
Seh11 2     Sec13 Like Protein2

External Ids:    HGNC: 303791   Entrez Gene: 819292   Ensembl: ENSG000000854157   OMIM: 6092635   UniProtKB: Q96EE33   

Export aliases for SEH1L gene to outside databases

Previous GC identifers: GC18P012939 GC18P012901


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SEH1L:
The protein encoded by this gene is part of a nuclear pore complex, Nup107-160. This protein contains WD repeats and
shares 34% amino acid identity with yeast Seh1 and 30% identity with yeast Sec13. All constituents of the Nup107-160
complex, including this protein, specifically localize to kinetochores in mitosis. Two alternatively spliced
transcript variants encoding distinct isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: SEH1_HUMAN, Q96EE3
Function: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is
required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore
microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of
the Nup107-160 subcomplex to the kinetochore




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NC_018929.1  NT_010859.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEH1L gene promoter:
         Max1   AML1a   FOXL1   GATA-2   c-Ets-1   GATA-1   FOXO4   MRF-2   En-1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSEH1L promoter sequence
   Search SABiosciences Chromatin IP Primers for SEH1L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEH1L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18p11.21   Ensembl cytogenetic band:  18p11.21   HGNC cytogenetic band: 18p11.21

SEH1L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEH1L gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P012947:  view genomic region     (about GC identifiers)

Start:
12,947,132 bp from pter      End:
12,987,535 bp from pter
Size:
40,404 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SEH1_HUMAN, Q96EE3 (See protein sequence)
Recommended Name: Nucleoporin SEH1  
Size: 360 amino acids; 39649 Da
Subunit: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex includes
NUP160, NUP133, NUP107, NUP98, NUP85, NUP43, NUP37, SEH1 and SEC13. The SEH1 subunit appears to be only weakly
associated with the Nup107-160 subcomplex
Subcellular location: Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex
Secondary accessions: A8K5B1 Q8NFU6 Q96MH3 Q9C069
Alternative splicing: 2 isoforms:  Q96EE3-2   Q96EE3-1   (Contains a phosphoserine at position 365)

Explore the universe of human proteins at neXtProt for SEH1L: NX_Q96EE3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96EE3

  • SEH1L Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001013455.1  NP_112493.2  

    ENSEMBL proteins: 
     ENSP00000467605   ENSP00000262124   ENSP00000466959   ENSP00000382779   ENSP00000467276  
     ENSP00000466234  
    Reactome Protein details: Q96EE3
    Human Recombinant Protein Products: 
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    Novus Biologicals SEH1L Lysate
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SEH1L

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000776colocalizes with kinetochore IDA15146057
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0005635nuclear envelope TAS--
    GO:0005829cytosol TAS--
    GO:0031080nuclear pore outer ring NAS17363900


    SEH1L for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SEH1L for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96EE3

    ProtoNet protein and cluster: Q96EE3

    UniProtKB/Swiss-Prot: SEH1_HUMAN, Q96EE3
    Similarity: Belongs to the WD repeat SEC13 family
    Similarity: Contains 6 WD repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: SEH1_HUMAN, Q96EE3
    Function: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is
    required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore
    microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of
    the Nup107-160 subcomplex to the kinetochore

    miRNA
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    miRTarBase miRNAs that target SEH1L:
    hsa-mir-210 (MIRT003158)

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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SEH1L
    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate SEH1L (see all 25):
    hsa-miR-21* hsa-miR-4311 hsa-miR-520d-5p hsa-miR-15a hsa-miR-424 hsa-miR-508-5p hsa-miR-23a hsa-miR-589
    SwitchGear 3'UTR luciferase reporter plasmidSEH1L 3' UTR sequence
    Inhib. RNA
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    2 GenomeRNAi human phenotypes for SEH1L:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Seh1l):
     mortality/aging 

    SEH1L for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/13 super-pathways (see all 13About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus
    8/11 pathways (see all 11)
    Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus1.00
    Interactions of Vpr with host cellular proteins0.70
    Nuclear import of Rev protein0.76
    Glucose transport0.57
    Vpr-mediated nuclear import of PICs0.76
    Hexose transport0.55
    Regulation of Glucokinase by Glucokinase Regulatory Protein0.75
    ISG15 antiviral mechanism0.49
    2M Phase
    M Phase1.00
    Mitotic Anaphase0.85
    Mitotic M-M/G1 phases0.88
    Separation of Sister Chromatids0.80
    Mitotic Metaphase and Anaphase0.85
    3Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion1.00
    Mitotic Prometaphase0.93
    Kinetochore assembly0.96
    4Cytokine Signaling in Immune system
    Cytokine Signaling in Immune system1.00
    Interferon Signaling0.61
    5HIV Infection
    HIV Infection1.00
    Host Interactions of HIV factors0.64

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/33        Reactome Pathways for SEH1L (see all 33)
        Mitotic Prometaphase
    Interactions of Rev with host cellular proteins
    Rev-mediated nuclear export of HIV-1 RNA
    Interferon Signaling
    Vpr-mediated nuclear import of PICs


    1         Kegg Pathway  (Kegg details for SEH1L):
        RNA transport


    SEH1L for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEH1L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/846 Interacting proteins for SEH1L (Q96EE32, 3 ENSP000003827794) via UniProtKB, MINT, STRING, and/or I2D (see all 846)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SNRNP200O756432, 3MINT-7945693 MINT-7947479 I2D: score=2 
    ARCN1P484442, 3MINT-7945693 MINT-7947479 I2D: score=1 
    CCT4P509912, 3MINT-7945693 MINT-7947479 I2D: score=1 
    CCT6AP402272, 3MINT-7945693 MINT-7947479 I2D: score=1 
    COPAP536212, 3MINT-7945693 MINT-7947479 I2D: score=1 
    About this table

    Gene Ontology (GO): 5/17 biological process terms (GO ID links to tree view) (see all 17):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000087M phase of mitotic cell cycle TAS--
    GO:0000236mitotic prometaphase TAS--
    GO:0000278mitotic cell cycle TAS--
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006999nuclear pore organization IMP15146057


    SEH1L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SEH1L
    Search CenterWatch for drugs/clinical trials and news about SEH1L / SEH1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SEH1L gene (2 alternative transcripts): 
    NM_001013437.1  NM_031216.3  

    Unigene Cluster for SEH1L:

    SEH1-like (S. cerevisiae)
    Hs.301048  [show with all ESTs]
    Unigene Representative Sequence: AK226075
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000592170 ENST00000262124(uc002krr.3) ENST00000585730 ENST00000399892(uc002krq.3)
    ENST00000589446 ENST00000587761 ENST00000588251 ENST00000592582 ENST00000590843
    ENST00000590032

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    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate SEH1L (see all 25):
    hsa-miR-21* hsa-miR-4311 hsa-miR-520d-5p hsa-miR-15a hsa-miR-424 hsa-miR-508-5p hsa-miR-23a hsa-miR-589
    SwitchGear 3'UTR luciferase reporter plasmidSEH1L 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEH1L
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    Additional cDNA sequence: 

    AF136976.1 AF255625.1 AF431970.1 AF514996.1 AK056940.1 AK226075.1 AK291226.1 AK314403.1 
    BC012430.1 

    11 DOTS entries:

    DT.454339  DT.100669516  DT.86858657  DT.100779898  DT.100769841  DT.95277877  DT.100045767  DT.100737411 
    DT.100779899  DT.92019238  DT.92429665 

    24/202 AceView cDNA sequences (see all 202):

    CR603544 CK431020 BM839828 BM556427 CA444644 AI683260 BQ431741 AA568797 
    CR620641 Z45217 AI040618 AA329797 AW236400 AW576354 BX459540 BU737231 
    BI792987 BI761369 BU624164 BX398263 BM542964 AA768710 BQ962624 AI004519 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SEH1L (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12
    SP1:        -                                   -                                         -           -               
    SP2:        -                                   -                                         -           -     -         
    SP3:        -                                                                                                         
    SP4:        -           -                       -                                                                     
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for SEH1L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SEH1L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TATTACAACC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SEH1L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SEH1L

    SOURCE GeneReport for Unigene cluster: Hs.301048
        SABiosciences Custom PCR Arrays for SEH1L
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEH1L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SEH1L gene from 9/33 species (see all 33)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves SEH1L1 SEH1-like (S. cerevisiae) 85.28(n)
    94.03(a)
      100859886  XM_003640799.1  XP_003640847.1 
    lizard
    (Anolis carolinensis)
    Reptilia SEH1L6
    --
    89(a)
    1 ↔ 1
    4(42878056-42883744)
    African clawed frog
    (Xenopus laevis)
    Amphibia CF284463.12   -- 80.91(n)    CF284463.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AY398414.12   -- 75.99(n)   334749  AY398414.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nup44A1 Nucleoporin 44A 57.66(n)
    57.66(a)
      35762  NM_165583.1  NP_724638.1 
    worm
    (Caenorhabditis elegans)
    Secernentea npp-181 Protein NPP-18 52.33(n)
    43.67(a)
      176748  NM_067339.3  NP_499740.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SEH1(YGL100W)4
    SEH11
    Nuclear pore protein of the conserved Nup84p complex more4
    Seh1p1
    50.79(n)1
    41.22(a)1
      7(313234-314283)4
    8527781, 4  NP_011415.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SEH1H6
    transducin/WD-40 repeat-containing protein
    21(a)
    1 ↔ 1
    1(23881512-23883297)
    rice
    (Oryza sativa)
    Liliopsida --
    WD domain, G-beta repeat domain containing protein...
    24(a)
    1 ↔ 1
    1(24702727-24707867)


    ENSEMBL Gene Tree for SEH1L (if available)
    TreeFam Gene Tree for SEH1L (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/748 NCBI SNPs in SEH1L are shown (see all 748    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1403077821,2
    --12946077(+) AGATTC/GCCATT 2 -- us2k10--------
    rs1872520101,2
    --12946106(+) GTCAAA/TACCAT 2 -- us2k10--------
    rs1453249771,2
    --12946209(+) CGCGTA/GATACT 2 -- us2k10--------
    rs756873031,2
    F,--12946314(+) AATGAT/GGTGTC 2 -- us2k12Minor allele frequency- G:0.03NA EA 240
    rs771746341,2
    C,F,--12946498(+) GTTTCA/CCCTAA 2 -- us2k14Minor allele frequency- C:0.06CSA WA EA 242
    rs1180601891,2
    C,F,--12946519(+) CACTCC/TCACTC 2 -- us2k11Minor allele frequency- T:0.03EA 120
    rs80852571,2
    C,F,A,H,--12946528(+) TCTGAT/CAATCT 2 -- us2k18Minor allele frequency- C:0.05NS NA WA 912
    rs1379181111,2
    --12946656(+) TTTCTC/TTGGAA 2 -- us2k10--------
    rs1423620081,2
    --12946691(+) AGTTAC/TAGTTG 2 -- us2k10--------
    rs1500752171,2
    --12946722(+) TGGGGC/TCCACC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for SEH1L (12947132 - 12987535 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SEH1L: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEH1L
    DNA2.0 Custom Variant and Variant Library Synthesis for SEH1L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SEH1L for disorders           About GeneDecksing

    OMIM gene information: 609263    OMIM disorders: --

    3 diseases for SEH1L:    About MalaCards
    anonychia congenita    hepatitis    malaria

    1 disease from the University of Copenhagen DISEASES database for SEH1L:
    Nail disease

    Export disorders for SEH1L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SEH1L gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with SEH1L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Proteomic analysis of the mammalian nuclear pore complex. (PubMed id 12196509)1, 2, 3 Cronshaw J.M.... Matunis M.J. (2002)
    2. Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex. (PubMed id 17360435)1, 2 Glavy J.S.... Chait B.T. (2007)
    3. The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. (PubMed id 17363900)1, 2 Zuccolo M.... Doye V. (2007)
    4. The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis. (PubMed id 15146057)1, 2 Loieodice I.... Doye V. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Sec13 shuttles between the nucleus and the cytoplasm and stably interacts with Nup96 at the nuclear pore complex. (PubMed id 14517296)1, 3 Enninga J....Fontoura B.M. (2003)
    8. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    9. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    10. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81929 HGNC: 30379 AceView: SEH1L Ensembl:ENSG00000085415 euGenes: HUgn81929
    ECgene: SEH1L Kegg: 81929 H-InvDB: SEH1L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SEH1L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SEH1L gene:
    Search GeneIP for patents involving SEH1L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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