Aliases for SEC62 Gene
External Ids for SEC62 Gene
Previous HGNC Symbols for SEC62 Gene
Previous GeneCards Identifiers for SEC62 Gene
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
GeneCards Summary for SEC62 Gene
SEC62 (SEC62 Homolog, Preprotein Translocation Factor) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum and Unfolded Protein Response (UPR). Gene Ontology (GO) annotations related to this gene include receptor activity and ATPase activity, coupled to transmembrane movement of substances.
UniProtKB/Swiss-Prot for SEC62 Gene
Required for preprotein translocation.