Aliases for SEC61G Gene
External Ids for SEC61G Gene
Previous GeneCards Identifiers for SEC61G Gene
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for SEC61G Gene
SEC61G (Sec61 Gamma Subunit) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include protein transporter activity and P-P-bond-hydrolysis-driven protein transmembrane transporter activity.
UniProtKB/Swiss-Prot for SEC61G Gene
Necessary for protein translocation in the endoplasmic reticulum.