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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEC61G Gene

protein-coding   GIFtS: 56
GCID: GC07M054787

Sec61 Gamma Subunit

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sec61 Gamma Subunit1 2
SSS12
Protein Transport Protein SEC61 Gamma Subunit2
Protein Transport Protein Sec61 Subunit Gamma2

External Ids:    HGNC: 182771   Entrez Gene: 234802   Ensembl: ENSG000001324327   OMIM: 6092155   UniProtKB: P600593   

Export aliases for SEC61G gene to outside databases

Previous GC identifers: GC07M054284 GC07M054527 GC07M054561 GC07M054594 GC07M054657


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SEC61G Gene:
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum
(ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across
and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma.
This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein
have been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for SEC61G Gene: 
SEC61G (Sec61 gamma subunit) is a protein-coding gene. Diseases associated with SEC61G include cholera, and among its related super-pathways are ER-Phagosome pathway and Viral mRNA Translation. GO annotations related to this gene include protein transporter activity and P-P-bond-hydrolysis-driven protein transmembrane transporter activity.

UniProtKB/Swiss-Prot: SC61G_HUMAN, P60059
Function: Necessary for protein translocation in the endoplasmic reticulum (By similarity)

Gene Wiki entry for SEC61G Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_033968.6  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEC61G gene promoter:
         TBP   Elk-1   IRF-1   XBP-1   Egr-4   Evi-1   Max   Egr-2   TFIID   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SEC61G promoter sequence
   Search SABiosciences Chromatin IP Primers for SEC61G

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC61G


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p11.2   Ensembl cytogenetic band:  7p11.2   HGNC cytogenetic band: 7p11.2

SEC61G Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEC61G gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M054787:  view genomic region     (about GC identifiers)

Start:
54,819,940 bp from pter      End:
54,827,667 bp from pter
Size:
7,728 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 54,825,706-54,832,698     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SC61G_HUMAN, P60059 (See protein sequence)
Recommended Name: Protein transport protein Sec61 subunit gamma  
Size: 68 amino acids; 7741 Da
Subunit: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity)
Secondary accessions: B2R4J0 P38384 Q6IB25

Explore the universe of human proteins at neXtProt for SEC61G: NX_P60059

Explore proteomics data for SEC61G at MOPED 

SEC61G Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

SEC61G Protein Expression

REFSEQ proteins (2 alternative transcripts): 
NP_001012474.1  NP_055117.1  

ENSEMBL proteins: 
 ENSP00000378906   ENSP00000388337   ENSP00000409884   ENSP00000341538  
Reactome Protein details: P60059
Human Recombinant Protein Products for SEC61G: 
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Novus Biologicals SEC61G Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp. 

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--
GO:0005789endoplasmic reticulum membrane IEA--
GO:0016020membrane IDA--
GO:0016021integral to membrane IEA--

SEC61G for ontologies           About GeneDecksing



SEC61G Antibody Products: 
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LSBio Antibodies in human, mouse, rat for SEC61G 

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
3 InterPro protein domains:
 IPR008158 Translocase_Sec61-g
 IPR023391 Prot_translocase_SecE_dom
 IPR001901 Translocase_SecE/Sec61-g

Graphical View of Domain Structure for InterPro Entry P60059

ProtoNet protein and cluster: P60059

1 Blocks protein domain: IPB001901 Protein secE/sec61-gamma protein

UniProtKB/Swiss-Prot: SC61G_HUMAN, P60059
Similarity: Belongs to the SecE/SEC61-gamma family


SEC61G for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: SC61G_HUMAN, P60059
Function: Necessary for protein translocation in the endoplasmic reticulum (By similarity)

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008565protein transporter activity ISS--
GO:0015450P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEA--
     
SEC61G for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for SEC61G:
 Increased gamma-H2AX phosphory 

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for SEC61G 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SEC61G

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SEC61G 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SEC61G 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SEC61G
1 QIAGEN miScript miRNA Assays for microRNA that regulate SEC61G:
hsa-miR-32*
SwitchGear 3'UTR luciferase reporter plasmidSEC61G 3' UTR sequence
Inhib. RNA
Products:
    
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Gene Editing
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Clone
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GenScript: all cDNA clones in your preferred vector (see all 2): SEC61G (NM_001012456)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SEC61G
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC61G
Sirion Biotech Customized lentivirus for stable overexpression of SEC61G 
                     Customized lentivirus expression plasmids for stable overexpression of SEC61G 

Cell Line
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Search LifeMap BioReagents cell lines for SEC61G
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC61G


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for SEC61G About   (see all 13)                                                                                              See pathways by source

SuperPathContained pathways About
1CDK-mediated phosphorylation and removal of Cdc6
ER-Phagosome pathway0.81
Antigen processing-Cross presentation0.81
2Viral mRNA Translation
Translation0.78
SRP-dependent cotranslational protein targeting to membrane0.77
3Regulation of degradation of wt-CFTR
Regulation of degradation of deltaF508 CFTR in CF0.59
Regulation of degradation of wt-CFTR0.59
4Immune System
Immune System0.56
Adaptive Immune System0.56
5Immune response Antigen presentation by MHC class I
Immune response Antigen presentation by MHC class I0.92

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 EMD Millipore Pathway for SEC61G
    Immune response Antigen presentation by MHC class I

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for SEC61G
    Cholera Infection

3 GeneGo (Thomson Reuters) Pathways for SEC61G
    Immune response Antigen presentation by MHC class I
Regulation of degradation of deltaF508 CFTR in CF
Regulation of degradation of wt-CFTR

5/9        Reactome Pathways for SEC61G (see all 9)
    Translation
Antigen processing-Cross presentation
SRP-dependent cotranslational protein targeting to membrane
Adaptive Immune System
ER-Phagosome pathway


4         Kegg Pathways  (Kegg details for SEC61G):
    Protein export
Protein processing in endoplasmic reticulum
Phagosome
Vibrio cholerae infection


SEC61G for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEC61G

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/144 Interacting proteins for SEC61G (P600593 ENSP000003415384) via UniProtKB, MINT, STRING, and/or I2D (see all 144)
InteractantInteraction Details
GeneCardExternal ID(s)
CREB3O438893I2D: score=1 
KRT81Q145333I2D: score=1 
RBL1P287493I2D: score=1 
FAUENSP000002792594STRING: ENSP00000279259
PSMA2ENSP000002233214STRING: ENSP00000223321
About this table

Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0002474antigen processing and presentation of peptide antigen via MHC class I TAS--
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS--
GO:0006412translation TAS--
GO:0006605protein targeting ----
GO:0006614SRP-dependent cotranslational protein targeting to membrane TAS--

SEC61G for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SEC61G (SC61G)

Search CenterWatch for drugs/clinical trials and news about SEC61G / SC61G

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SEC61G gene (2 alternative transcripts): 
NM_001012456.1  NM_014302.3  

Unigene Cluster for SEC61G:

Sec61 gamma subunit
Hs.488282  [show with all ESTs]
Unigene Representative Sequence: CB992038
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000395535(uc003tqf.3) ENST00000415949 ENST00000450622 ENST00000460484
ENST00000480303 ENST00000461536 ENST00000352861(uc003tqg.3)
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SEC61G
1 QIAGEN miScript miRNA Assays for microRNA that regulate SEC61G:
hsa-miR-32*
SwitchGear 3'UTR luciferase reporter plasmidSEC61G 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for SEC61G
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEC61G
Clone
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OriGene clones in human, mouse for SEC61G (see all 13)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): SEC61G (NM_001012456)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SEC61G
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC61G
Sirion Biotech Customized lentivirus for stable overexpression of SEC61G 
                     Customized lentivirus expression plasmids for stable overexpression of SEC61G 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for SEC61G
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SEC61G
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC61G
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC61G

Additional mRNA sequence: 

AF054184.1 AF086539.1 AK308617.1 AK311845.1 BC009480.2 BC051840.1 CR456979.1 

10 DOTS entries:

DT.315765  DT.97843698  DT.91639335  DT.95273062  DT.121080211  DT.85103649  DT.100689520  DT.121080217 
DT.92427303  DT.95181706 

24/222 AceView cDNA sequences (see all 222):

AI417545 AA769837 F29799 AA436472 BM833099 AA936788 AI350224 AI189101 
AA862093 BM856539 AI302731 AA553979 AI273541 BM663277 AA526594 F26490 
F30408 BX280476 AF086539 CB117085 AI805874 AW304394 AI027299 BM765803 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for SEC61G    About this scheme

ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b ^ 4a · 4b ^ 5
SP1:                                -                       -         
SP2:                                                        -         
SP3:                                -                                 
SP4:                                -                                 
SP5:                                -                                 


ECgene alternative splicing isoforms for SEC61G

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SEC61G expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCAACAGCAA
SEC61G Expression
About this image


See SEC61G Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SEC61G

SOURCE GeneReport for Unigene cluster: Hs.488282
    SABiosciences Custom PCR Arrays for SEC61G
Primer
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC61G
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC61G

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for SEC61G gene from 10/19 species (see all 19)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Gm101771 , 5 predicted gene 101771, 5 92.16(n)1
100(a)1
  9 (20.74 cM)5
1000425611  XM_001478520.41  XP_001478570.11 
 372529225 
chicken
(Gallus gallus)
Aves SEC61G1 Sec61 gamma subunit 88.73(n)
100(a)
  776639  XM_001236151.2  XP_001236152.2 
lizard
(Anolis carolinensis)
Reptilia SEC61G6
Uncharacterized protein
100(a)
1 ↔ 1
6(51423605-51429589)
African clawed frog
(Xenopus laevis)
Amphibia sec61g-A2 Sec61 gamma subunit 80.93(n)    AJ009316.1 
zebrafish
(Danio rerio)
Actinopterygii hmzehn12312 hmzehn1231 83.72(n)   337740  57082219 
fruit fly
(Drosophila melanogaster)
Insecta CG88601 CG8860 70.15(n)
86.57(a)
  36310  NM_136894.2  NP_610738.1 
worm
(Caenorhabditis elegans)
Secernentea emo-11 Protein EMO-1 75.12(n)
86.57(a)
  179510  NM_073377.4  NP_505778.1 
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SSS16
Subunit of the Sec61p translocation complex (Sec61...
38(a)
1 ↔ 1
IV(616928-617170)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G249201 protein transport protein sec61 subunit gamma-1 66.17(n)
73.13(a)
  828594  NM_118624.3  NP_194222.1 
rice
(Oryza sativa)
Liliopsida Os02g01784001 hypothetical protein 59.7(n)
73.13(a)
  4328492  NM_001052611.1  NP_001046076.1 


ENSEMBL Gene Tree for SEC61G (if available)
TreeFam Gene Tree for SEC61G (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/127 SNPs in SEC61G are shown (see all 127)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1853266841,2
--54819522(+) TCCAAA/TGTAAT 2 -- ds50010--------
rs1413484511,2
--54819542(+) AGGTAC/GGGCCT 2 -- ds50010--------
rs1892865981,2
--54819681(+) TCACCA/GGACAC 2 -- ds50010--------
rs102507881,2
C--54819722(+) cccagC/Tctcca 2 -- ds50010--------
rs580463311,2
C--54819757(+) ATTTAC/TAAATT 2 -- ds50011Minor allele frequency- T:0.50WA 2
rs1819657631,2
--54819851(+) CTTTCA/GTTTCT 2 -- ds50010--------
rs1458179421,2
--54819878(+) TTCAGA/GGAAAG 2 -- ds50010--------
rs1837208781,2
--54819977(+) AAATAG/TAAAAC 2 -- ut310--------
rs1883932941,2
--54819998(+) GAAAAA/GAAAAA 2 -- ut310--------
rs2004575281,2
C--54820007(-) TTTGTG/TGGTTT 2 -- ut310--------

HapMap Linkage Disequilibrium report for SEC61G (54819940 - 54827667 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for SEC61G:    About this table     
Variant IDTypeSubtypePubMed ID
esv2734425CNV Deletion23290073

SABiosciences Cancer Mutation PCR Assays
1 SABiosciences qBiomarker Copy Number PCR Array containing SEC61G:
Glioma
SeqTarget long-range PCR primers for resequencing SEC61G
DNA2.0 Custom Variant and Variant Library Synthesis for SEC61G

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 609215    OMIM disorders: --

2 diseases for SEC61G:    About MalaCards
cholera    


SEC61G for disorders           About GeneDecksing

Genetic Association Database (GAD): SEC61G

Export disorders for SEC61G gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for SEC61G gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with SEC61G)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
  3. The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment. (PubMed id 10212142)1, 3 Greenfield J.J. and High S. (1999)
  4. Evolutionary conservation of components of the protein translocation complex. (PubMed id 8107851)1, 3 Hartmann E....Rapoport T.A. (1994)
  5. Chromosome 7p11.2 (EGFR) variation influences glioma risk. (PubMed id 21531791)4 Sanson M....Simon M. (2011)
  6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
  7. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
  8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
  9. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 23480 HGNC: 18277 AceView: SEC61G Ensembl:ENSG00000132432 euGenes: HUgn23480
ECgene: SEC61G Kegg: 23480 H-InvDB: SEC61G

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for SEC61G Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for SEC61G Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SEC61G gene:
Search GeneIP for patents involving SEC61G

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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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