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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEC31B Gene

protein-coding   GIFtS: 53
GCID: GC10M102237

SEC31 homolog B (S. cerevisiae)

(Previous name: SEC31-like 2 (S. cerevisiae) )
(Previous symbol: SEC31L2)
 Explore 3 diseases affiliated with
SEC31B via our new
 Human Malady Compendium 
Biological research products
for SEC31B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
SEC31 Homolog B (S. Cerevisiae)1 2     DKFZP434M1831
SEC31B-11 2 3     SEC31-Like 2 (S. Cerevisiae)1
SEC31L21 2 3     Protein Transport Protein Sec31B2
SEC31-Like Protein 22 3     SEC31-Like 22
SEC31-Related Protein B2 3     Secretory Pathway Component Sec31B-12

External Ids:    HGNC: 231971   Entrez Gene: 259562   Ensembl: ENSG000000758267   OMIM: 6102585   UniProtKB: Q9NQW13   

Export aliases for SEC31B gene to outside databases

Previous GC identifer: GC10M095875


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SEC31B:
This gene encodes a protein of unknown function. The protein has moderate similarity to rat VAP1 protein which is an
endosomal membrane-associated protein, containing a putative Ca2+/calmodulin-dependent kinase II phosphorylation site.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: SC31B_HUMAN, Q9NQW1
Function: As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from
the endoplasmic reticulum




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEC31B gene promoter:
         SRF   RP58   SRF (504 AA)   MIF-1   CUTL1   Tal-1beta   Max   NF-Y   CBF(2)   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSEC31B promoter sequence
   Search SABiosciences Chromatin IP Primers for SEC31B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC31B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.31   Ensembl cytogenetic band:  10q24.31   HGNC cytogenetic band: 10q24.32

SEC31B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEC31B gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M102237:  view genomic region     (about GC identifiers)

Start:
102,246,399 bp from pter      End:
102,289,628 bp from pter
Size:
43,230 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SC31B_HUMAN, Q9NQW1 (See protein sequence)
Recommended Name: Protein transport protein Sec31B  
Size: 1179 amino acids; 128697 Da
Subunit: COPII is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex and SAR1. SEC13 and SEC31
make a 2:2 tetramer that forms the edge element of the COPII outer coat. The tetramer self-assembles in multiple
copies to form the complete polyhedral cage. Interacts (via WD 8) with SEC13 (By similarity). Interacts with SEC31A
Subcellular location: Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein;
Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein
Secondary accessions: B7ZM75 Q6MZS3 Q86UF0 Q9Y4Q8
Alternative splicing: 5 isoforms:  Q9NQW1-1   Q9NQW1-2   Q9NQW1-3   Q9NQW1-4   Q9NQW1-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SEC31B: NX_Q9NQW1

Post-translational modifications:

  • Monoubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex, leading to regulate the size of COPII coats1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NQW1

  • SEC31B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056305.1  
    ENSEMBL proteins: 
     ENSP00000359370   ENSP00000435359   ENSP00000432260   ENSP00000391178   ENSP00000359354  
     ENSP00000442621  

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    Uscn Proteins for SEC31B

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0012507ER to Golgi transport vesicle membrane IEA--
    GO:0044432endoplasmic reticulum part IDA--


    SEC31B for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SEC31B for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9NQW1

    ProtoNet protein and cluster: Q9NQW1

    UniProtKB/Swiss-Prot: SC31B_HUMAN, Q9NQW1
    Similarity: Belongs to the WD repeat SEC31 family
    Similarity: Contains 8 WD repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: SC31B_HUMAN, Q9NQW1
    Function: As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from
    the endoplasmic reticulum

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Clathrin-dependent protein traffic
    Clathrin-dependent protein traffic1.00
    wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)0.37
    Transport_Clathrin-coated vesicle cycle0.66
    2COPII (Coat Protein 2) Mediated Vesicle Transport
    Normal wtCFTR traffic / ER-to-Golgi 0.36
    Delta508-CFTR traffic / ER-to-Golgi in CF0.36
    3Protein processing in endoplasmic reticulum
    Protein processing in endoplasmic reticulum1.00
    4Regulation of Cholesterol Biosynthesis by SREBP (SREBF)
    SREBP signalling0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for SEC31B
        Clathrin-dependent protein traffic


    4 GeneGo (Thomson Reuters) Pathways for SEC31B
        wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
    Delta508-CFTR traffic / ER-to-Golgi in CF
    Normal wtCFTR traffic / ER-to-Golgi
    Transport Clathrin-coated vesicle cycle

    1 BioSystems Pathway for SEC31B 
        SREBP signalling


    1         Kegg Pathway  (Kegg details for SEC31B):
        Protein processing in endoplasmic reticulum


    SEC31B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEC31B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/566 Interacting proteins for SEC31B (Q9NQW12, 3 ENSP000003593704) via UniProtKB, MINT, STRING, and/or I2D (see all 566)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    SEC23BQ154372, ENSP000002625444MINT-7945693 STRING: ENSP00000262544
    SNW1Q135732, ENSP000002615314MINT-7945693 STRING: ENSP00000261531
    ABCF1Q8NE712MINT-7945693
    ABCF3Q9NUQ82MINT-7945693
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport IEA--
    GO:0016192vesicle-mediated transport IEA--


    SEC31B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SEC31B
    Search CenterWatch for drugs/clinical trials and news about SEC31B / SC31B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SEC31B gene (2 alternative transcripts): 
    NM_015490.3  NM_198138.1  

    Unigene Cluster for SEC31B:

    SEC31 homolog B (S. cerevisiae)
    Hs.18889  [show with all ESTs]
    Unigene Representative Sequence: BC071580
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370345(uc010qpo.1 uc001krc.1) ENST00000485800 ENST00000492667
    ENST00000479697(uc001krd.1 uc001krf.1) ENST00000462434(uc001kre.1 uc010qpp.1 uc009xwn.1)
    ENST00000469546 ENST00000482456 ENST00000468279 ENST00000484848(uc001krg.1)
    ENST00000469824 ENST00000498298 ENST00000494350 ENST00000490567 ENST00000480905
    ENST00000451524 ENST00000370329 ENST00000535773

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    Additional cDNA sequence: 

    AF274863.1 AK128343.1 AK289975.1 AK294551.1 AL080141.1 BC034946.1 BC053949.1 BC071580.1 
    BC144312.1 BC144313.1 BX640914.1 

    14 DOTS entries:

    DT.414090  DT.100777583  DT.95144885  DT.101971667  DT.100023015  DT.92016427  DT.87011974  DT.97827424 
    DT.121302765  DT.100737571  DT.102835184  DT.121302720  DT.121302739  DT.91866804 

    24/681 AceView cDNA sequences (see all 681):

    CF127327 AA292868 BM769403 BM904902 BU679046 CF129324 BQ684349 BQ878253 
    BQ954364 CA772034 CF130298 BU168076 CF130332 NM_198138 N23411 AA400149 
    AA365486 BU183103 CF130119 CD673094 BU727112 BF663335 BX107827 NM_015490 

    GeneLoc Exon Structure

    5/16 Alternative Splicing Database (ASD) splice patterns (SP) for SEC31B (see all 16)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15a · 15b · 15c ^
    SP1:              -                       -           -                       -                                                                             -   
    SP2:              -                                   -                       -                                                     -     -                 -   
    SP3:              -     -                             -                       -                                                     -                       -   
    SP4:                                      -           -                       -                                                     -                       -   
    SP5:                                                                    -     -                                                     -     -                 -   

    ExUns: 16 ^ 17 ^ 18a · 18b · 18c · 18d ^ 19a · 19b · 19c ^ 20 ^ 21 ^ 22a · 22b · 22c ^ 23 ^ 24a · 24b · 24c · 24d ^ 25a · 25b ^ 26a · 26b · 26c ^ 27 ^ 28 ^
    SP1:              -     -                             -                 -           -           -     -                       -                 -               
    SP2:              -     -                             -                 -           -           -     -                       -                 -               
    SP3:              -     -                             -                 -           -           -     -     -     -           -                 -               
    SP4:              -     -                             -                 -           -           -     -     -     -           -                 -               
    SP5:              -     -                             -                 -                                                                                       

    ExUns: 29a · 29b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for SEC31B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SEC31B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SEC31B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SEC31B

    SOURCE GeneReport for Unigene cluster: Hs.18889

    UniProtKB/Swiss-Prot: SC31B_HUMAN, Q9NQW1
    Tissue specificity: Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in
    testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular
    cells (at protein level)

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SEC31B gene from 7/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sec31b1 , 5 Sec31 homolog B (S. cerevisiae)1, 5 82.66(n)1
    79.57(a)1
      19 (37.98 cM)5
    2406671  NM_001033343.11  NP_001028515.11 
     445169575 
    chicken
    (Gallus gallus)
    Aves SEC31B1 SEC31 homolog B (S. cerevisiae) 65.73(n)
    60.43(a)
      423764  XM_003641494.1  XP_003641542.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sec31b1 Sec31 homolog B (S. cerevisiae) 58.22(n)
    52.55(a)
      100148383  XM_001921546.3  XP_001921581.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta sec316
    sec31
    29(a)
    1 → many
    2R(4781129-4786303)
    worm
    (Caenorhabditis elegans)
    Secernentea sec-316
    --
    20(a)
    possible ortholog
    IV(11365596-11371772)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G188301 transducin/WD-40 repeat-containing protein 43.93(n)
    34.96(a)
      838464  NM_101740.2  NP_173317.2 
    rice
    (Oryza sativa)
    Liliopsida Os07g06572001 hypothetical protein 44.09(n)
    33.87(a)
      4344154  NM_001067045.1  NP_001060510.1 


    ENSEMBL Gene Tree for SEC31B (if available)
    TreeFam Gene Tree for SEC31B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SEC31B gene
    SEC31A2  
    1 SIMAP similar gene for SEC31B using alignment to 5 protein entries:     SC31B_HUMAN (see all proteins):
    SEC31A

    SEC31B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/599 NCBI SNPs in SEC31B are shown (see all 599    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1492126761,2
    --102246040(+) AGCCCG/TCAGAC 1 -- ds50010--------
    rs1876295661,2
    --102246079(+) TAGCAA/TCCCCT 1 -- ds50010--------
    rs94198971,2
    C,A,H,--102246125(+) AGCCCT/CGAAGT 1 -- ds50016Minor allele frequency- C:0.20NA CSA WA EA 363
    rs1908491201,2
    --102246166(+) AGGCAC/TGGATG 1 -- ds50010--------
    rs1424825221,2
    --102246167(+) GGCACA/GGATGA 1 -- ds50010--------
    rs1834709661,2
    --102246335(+) GAATAA/GAGAGG 1 -- ds50010--------
    rs1877541081,2
    --102246372(+) CCCAGA/GGGAGG 1 -- ds50010--------
    rs753679211,2
    F,--102246430(+) GCACCA/GTTAAG 1 -- ut311Minor allele frequency- G:0.03WA 118
    rs29701,2
    C,F,O,A,H,--102246512(+) GGCTGC/TGAGGG 1 -- ut31 ese323Minor allele frequency- T:0.28MN EA NS NA WA 4228
    rs1468446751,2
    --102246696(+) CACAGC/TCTAAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SEC31B (102246399 - 102289628 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for SEC31B
         5 CNVs: 8665 9645 30514 2888 3818

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEC31B
    DNA2.0 Custom Variant and Variant Library Synthesis for SEC31B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SEC31B for disorders           About GeneDecksing

    OMIM gene information: 610258    OMIM disorders: --

    3 diseases for SEC31B:    About MalaCards
    stomatitis    alzheimer's disease    malaria

    1 disease from the University of Copenhagen DISEASES database for SEC31B:
    Stomatitis
    Human Genome Epidemiology (HuGE) Navigator: SEC31B (1 document)

    Export disorders for SEC31B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SEC31B gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with SEC31B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Sec31B: a family of new mammalian orthologues of yeast Sec31p that associate with the COPII coat. (PubMed id 16495487)1, 2, 3 Stankewich M.C.... Morrow J.S. (2006)
    2. Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport. (PubMed id 10788476)1, 2 Tang B.L....Hong W. (2000)
    3. Ubiquitin-dependent regulation of COPII coat size and function. (PubMed id 22358839)2 Jin L.... Rape M. (2012)
    4. Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. (PubMed id 17332742)1 Behzadnia N.... Luehrmann R. (2007)
    5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    6. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    9. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25956 HGNC: 23197 AceView: NDUFB8andSEC31L2 Ensembl:ENSG00000075826 euGenes: HUgn25956
    ECgene: SEC31B Kegg: 25956 H-InvDB: SEC31B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SEC31B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SEC31B gene:
    Search GeneIP for patents involving SEC31B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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