Aliases for SEC24C Gene
External Ids for SEC24C Gene
Previous GeneCards Identifiers for SEC24C Gene
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for SEC24C Gene
SEC24C (SEC24 Homolog C, COPII Coat Complex Component) is a Protein Coding gene. Diseases associated with SEC24C include Velocardiofacial Syndrome. Among its related pathways are Regulation of cholesterol biosynthesis by SREBP (SREBF) and Normal wtCFTR traffic / ER-to-Golgi. An important paralog of this gene is SEC24D.
UniProtKB/Swiss-Prot for SEC24C Gene
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.