SEC24B Gene
protein-coding GIFtS: 60
GCID: GC04P110354
|
|
SEC24 family, member B (S. cerevisiae)(Previous names: SEC24 (S. cerevisiae) related gene family, member B, SEC24...)
| |
Aliases for SEC24B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| SEC24 Family, Member B (S. Cerevisiae)1 2 | | SEC242 | | SEC24-Related Protein B2 3 | | Protein Transport Protein Sec24B2 | | SEC24 (S. Cerevisiae) Related Gene Family, Member B1 | | SEC24 Related Gene Family, Member B2 | | SEC24 Related Gene Family, Member B (S. Cerevisiae)1 | | Secretory Protein 242 |
Export aliases for SEC24B gene to outside databasesPrevious GC identifers: GC04P110811 GC04P110664 GC04P110813 GC04P110712 GC04P110574 GC04P106087 |
Summaries for SEC24B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SEC24B: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved invesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat proteincomplex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of thevesicle, and also in cargo selection and concentration. Two transcript variants encoding different isoforms have beenfound for this gene. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: SC24B_HUMAN, O95487Function: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmicreticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane,and vacuolar proteins from the endoplasmic reticulum to the Golgi complex Gene Wiki entry for SEC24B
|
Genomic Views for SEC24B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SEC24B gene promoter: C/EBPbeta ISGF-3 Arnt GATA-2 CREB HEN1 POU2F1 E2F-1 E2F deltaCREB Other transcription factors
Search SABiosciences Chromatin IP Primers for SEC24B
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC24B |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q25 Ensembl cytogenetic band: 4q25 HGNC cytogenetic band: 4q25SEC24B Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P110354: view genomic region
(about GC identifiers)
Start:
|
110,354,928 bp from pter |
End:
|
110,461,615 bp from pter |
Size:
|
106,688 bases |
Orientation:
|
plus strand |
|
Proteins for SEC24B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SC24B_HUMAN, O95487 (See
protein sequence)Recommended Name: Protein transport protein Sec24B Size: 1268 amino acids; 137418 Da
Subunit: COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and SAR1. SEC24B iscapable of forming heterodimers with SEC24A. Interacts with RNF139. Interacts with TMED2 and TMED10
Subcellular location: Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum membrane (Potential). Golgiapparatus membrane (Potential). Golgi apparatus membrane (By similarity)
Sequence caution: Sequence=CAA10335.1; Type=Frameshift; Positions=459, 483;
1 PDB 3D structure from and Proteopedia for SEC24B:3EH1 (3D)
 
Secondary accessions: B7ZKN4 Q0VG08Alternative splicing: 2 isoforms: O95487-1 O95487-2 Explore the universe of human proteins at neXtProt for SEC24B: NX_O95487
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95487 SEC24B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001036199.1 NP_006314.2 ENSEMBL proteins: ENSP00000428564 ENSP00000382051 ENSP00000265175 Reactome Protein details: O95487 Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
SEC24B for ontologies About GeneDecksing
SEC24B Antibody Products: Assay Products for SEC24B: |
Protein
Domains / Families for SEC24B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SEC24B for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O95487ProtoNet protein and cluster: O95487 5 Blocks protein families: IPB000425 MIP family IPB006895 Sec23/Sec24 zinc finger IPB006896 Sec23/Sec24 trunk domain IPB006900 Sec23/Sec24 helical domain IPB007123 Gelsolin region
UniProtKB/Swiss-Prot: SC24B_HUMAN, O95487Similarity: Belongs to the SEC23/SEC24 family. SEC24 subfamily |
Function for SEC24B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SC24B_HUMAN, O95487Function: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmicreticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane,and vacuolar proteins from the endoplasmic reticulum to the Golgi complex Genatlas biochemistry entry for SEC24B:SEC24 (S. cerevisiae) related gene family, member B
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC24B (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC24B (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SEC24B (NM_006323) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SEC24B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC24B  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC24B |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SEC24B for ontologies About GeneDecksing
Animal Models: 8 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Sec24b):
SEC24B for phenotypes About GeneDecksing
|
Pathways & Interactions for SEC24B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/14 super-pathways (see all 14) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | COPII (Coat Protein 2) Mediated Vesicle Transport | | | 2 | Clathrin-dependent protein traffic | | | 3 | Asparagine N-linked glycosylation | | | 4 | Immune System | | | 5 | Regulation of Cholesterol Biosynthesis by SREBP (SREBF) | |
Pathway sources See GeneCards unified pathways Show all pathways
1 EMD Millipore Pathway for SEC24B 1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for SEC24B 1
Cell Signaling Technology (CST) Pathway for SEC24B 4 GeneGo (Thomson Reuters) Pathways for SEC24B 1 BioSystems Pathway for SEC24B 
5/17
Reactome Pathways for SEC24B (see all 17)
1
Kegg Pathway (Kegg details for SEC24B):
SEC24B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEC24B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/104 Interacting proteins for SEC24B (O954873 ENSP000002651754) via UniProtKB, MINT, STRING, and/or I2D (see all 104)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I |
TAS | -- | | GO:0006886 | intracellular protein transport |
IEA | -- | | GO:0006888 | ER to Golgi vesicle-mediated transport |
TAS | -- | | GO:0016044 | cellular membrane organization |
TAS | -- | | GO:0016192 | vesicle-mediated transport |
TAS | 10075675 |
SEC24B for ontologies About GeneDecksing
|
Drugs & Compounds for SEC24B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SEC24B Search CenterWatch for drugs/clinical trials and news about SEC24B / SC24B 
|
Transcripts for SEC24B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SEC24B gene (2 alternative transcripts): NM_001042734.1 NM_006323.2 Unigene Cluster for SEC24B: SEC24 family, member B (S. cerevisiae) Hs.292472 [show with all ESTs]Unigene Representative Sequence: AJ1312453 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000504968 ENST00000399100 ENST00000265175(uc003hzk.3 uc003hzl.3 uc011cfp.2 uc011cfq.2 uc011cfr.2)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC24B (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC24B (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SEC24B (NM_006323) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SEC24B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC24B  |
Additional cDNA sequence: AJ131245.1 AK300278.1 AK304234.1 BC040137.1 BC117135.1 BC143268.1 BC143269.1 BC143276.1 9 DOTS entries: DT.217246 DT.91745497 DT.91699533 DT.40250563 DT.95306813 DT.95076348 DT.95304362 DT.40192305 DT.95351792 24/216 AceView cDNA sequences (see all 216): AI400478 AA318705 R37704 CD107859 Z43797 AI432147 BM837102 AW770467 AA234430 F03103 AI521142 AA234343 CR605949 BG575679 CN479501 Z39864 AI674128 CA449375 AI225122 BM022005 BM719316 BM354227 AI521685 NM_006323 GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for SEC24B (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21a | · | 21b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SEC24B
|
Expression for SEC24B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SEC24B expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AACTATAGAA
About this image See SEC24B Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SEC24B
SOURCE GeneReport for Unigene cluster: Hs.292472 UniProtKB/Swiss-Prot: SC24B_HUMAN, O95487Tissue specificity: Expressed in fibroblasts, hepatocytes, and lymphocytes SABiosciences Custom PCR Arrays for SEC24B
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SEC24B Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SEC24B | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC24B | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC24B | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC24B |
Orthologs for SEC24B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SEC24B gene from 9/36 species (see all 36) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
SEC24B1 |
SEC24 family, member B (S. cerevisiae) |
76.44(n) 78.79(a) |
  |
422523 NM_001031135.1 NP_001026306.1 |
lizard (Anolis carolinensis) |
Reptilia |
SEC24B6 |
-- |
69(a) |
1 ↔ 1 |
5(144556379-144591995) |
African clawed frog (Xenopus laevis) |
Amphibia |
CA987060.12 |
-- |
77.68(n) |
  |
CA987060.1 |
zebrafish (Danio rerio) |
Actinopterygii |
CF996861.12 |
-- |
74.31(n) |
  |
CF996861.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
sec241 |
CG1472-PA |
48.68(n) 44.87(a) |
  |
36025 NM_136687.4 NP_610531.1 |
worm (Caenorhabditis elegans) |
Secernentea |
sec-24.23 |
Yeast YIK9 like |
42(a) |
  |
IV(12356456-12360940) -- |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
SEC241 |
Sec24p |
44.96(n) 35.66(a) |
  |
854697 NP_012157.3 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
SEC24A6 |
sec24-like transport protein |
31(a) |
1 → many |
3(2245164-2250699) |
rice (Oryza sativa) |
Liliopsida |
-- |
protein transport protein Sec24-like, putative, ex... |
31(a) |
1 → many |
4(1853511-1860834) |
ENSEMBL Gene Tree for SEC24B (if available) TreeFam Gene Tree for SEC24B (if available)  |
Paralogs for SEC24B gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SEC24B gene
- SEC24A2 SEC24C2 SEC24D2
3 SIMAP similar genes for SEC24B using alignment to 2 protein entries: SC24B_HUMAN (see all proteins):SEC24A SEC24D SEC24C
SEC24B for paralogs About GeneDecksing
|
Genomic Variants for SEC24B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for SEC24B 1 CNV: 68784 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEC24B |
|
Disorders
/ Diseases for SEC24B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SEC24B for disorders About GeneDecksing
OMIM gene information: 607184
OMIM disorders: --
7 diseases for SEC24B: About MalaCardssitus inversus congenital dyserythropoietic anemia dyserythropoietic anemia alcohol dependence alcoholism anemia malaria 1 disease from the University of Copenhagen DISEASES database for SEC24B:Congenital dyserythropoietic anemia Human Genome Epidemiology (HuGE) Navigator: SEC24B (1 document) Export disorders for SEC24B gene to outside databases
|
Publications for SEC24B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SEC24B gene, integrated from 9 sources (see all 30): (articles sorted by number of sources associating them with SEC24B) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Sec24 proteins and sorting at the endoplasmic reticulum. (PubMed id 10075675)1, 2, 3, 9 Pagano A....Paccaud J.P. (1999)
- The sterol-sensing endoplasmic reticulum (ER) membran e protein TRC8 hampers ER to Golgi transport of sterol regulatory element-bindi ng protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cle avage. (PubMed id 19706601)1, 2 Irisawa M....Sato R. (2009)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- A family of mammalian proteins homologous to yeast Sec24p. (PubMed id 10329445)1, 3 Tang B.L....Hong W. (1999)
- Selective export of human GPI-anchored proteins from the endoplasmic reticulum. (PubMed id 20427317)2, 9 Bonnon C....Hauri H.P. (2010)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1 Kalsi G....Riley B.P. (2010)
- Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (2010)
|
External Searches for SEC24B gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SEC24B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SEC24B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SEC24B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SEC24B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SEC24B gene: Search GeneIP for patents involving SEC24B
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SEC24B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SEC24B | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SEC24B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SEC24B | | OriGene Protein Over-expression Lysate for SEC24B | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SEC24B | | OriGene 3'-UTR Clone for SEC24B | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC24B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC24B | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for SEC24B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SEC24B | | OriGene Custom Protein Services for SEC24B | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SEC24B | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEC24B | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC24B | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEC24B | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC24B | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC24B |
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| Antibodies & Assays for SEC24B  |
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 | | SEC24B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC24B |
|  |  |  | | | Search ThermoFisher Antibodies for SEC24B |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC24B |
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