Aliases for SEC23A Gene
External Ids for SEC23A Gene
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]
GeneCards Summary for SEC23A Gene
SEC23A (Sec23 Homolog A (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with SEC23A include craniolenticulosutural dysplasia. Among its related pathways are Class I MHC mediated antigen processing and presentation and Regulation of Cholesterol Biosynthesis by SREBP (SREBF). An important paralog of this gene is SEC23B.
UniProtKB/Swiss-Prot for SEC23A Gene
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex