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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEC22A Gene

protein-coding   GIFtS: 49
GCID: GC03P122920

SEC22 vesicle trafficking protein homolog A (S. cerevisiae)

(Previous name: SEC22 vesicle trafficking protein-like 2 (S. cerevisiae)...)
(Previous symbol: SEC22L2)
 Explore 1 disease affiliated with
SEC22A via
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 Human Malady Compendium 
Biological research products
for SEC22A    

Aliases
for SEC22A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
SEC22 Vesicle Trafficking Protein Homolog A (S. Cerevisiae)1 2     SEC22 Vesicle Trafficking Protein-Like 2 (S. Cerevisiae)1
SEC22L21 2 3 5     Sec22 Homolog2
SEC22 Vesicle-Trafficking Protein Homolog A2 3     SEC22 Vesicle Trafficking Protein-Like 22
SEC22 Vesicle-Trafficking Protein-Like 22 3     Vesicle-Trafficking Protein SEC22a2

External Ids:    HGNC: 202601   Entrez Gene: 269842   Ensembl: ENSG000001215427   OMIM: 6124425   UniProtKB: Q96IW73   

Export aliases for SEC22A gene to outside databases

Previous GC identifers: GC03P119643 GC03P124404 GC03P120295


Summaries
for SEC22A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SEC22A:
The protein encoded by this gene belongs to the member of the SEC22 family of vesicle trafficking proteins. This
protein has similarity to rat SEC22 and may act in the early stages of the secretory pathway. (provided by RefSeq, Nov
2008)

UniProtKB/Swiss-Prot: SC22A_HUMAN, Q96IW7
Function: May be involved in vesicle transport between the ER and the Golgi complex (By similarity)

Gene Wiki entry for SEC22A


Genomic Views
for SEC22A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEC22A gene promoter:
         TBP   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   LCR-F1   FOXJ2 (long isoform)   TFIID   FOXJ2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SEC22A promoter sequence
   Search SABiosciences Chromatin IP Primers for SEC22A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC22A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21.1   Ensembl cytogenetic band:  3q21.1   HGNC cytogenetic band: 3q21.1

SEC22A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEC22A gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P122920:  view genomic region     (about GC identifiers)

Start:
 122,920,774 bp from pter      End:
 122,992,983 bp from pter
Size:
 72,210 bases      Orientation:
 plus strand

Proteins
for SEC22A gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SC22A_HUMAN, Q96IW7 (See protein sequence)
Recommended Name: Vesicle-trafficking protein SEC22a  
Size: 307 amino acids; 34948 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)
Sequence caution: Sequence=AAD43013.1; Type=Frameshift; Positions=265, 288;
Secondary accessions: B2RE26 Q9Y682

Explore the universe of human proteins at neXtProt for SEC22A: NX_Q96IW7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96IW7

    • SEC22A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036562.2  
    ENSEMBL proteins: 
     ENSP00000417200   ENSP00000417972   ENSP00000420343   ENSP00000420128   ENSP00000419039  
     ENSP00000420574   ENSP00000417219   ENSP00000420015   ENSP00000310521  

    Human Recombinant Protein Products: 
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    OriGene Purified Protein: SEC22A
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    Novus Biologicals SEC22A Protein
    Novus Biologicals SEC22A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SEC22A

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral to membrane IEA--


    SEC22A for ontologies           About GeneDecksing



    SEC22A Antibody Products: 
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    Uscn ELISAs and CLIAs for SEC22A

    Protein Domains /
    Families
    for SEC22A gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SEC22A for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR010908 Longin_dom
     IPR027152 Sec22
     IPR011012 Longin-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96IW7

    ProtoNet protein and cluster: Q96IW7

    1 Blocks protein family: IPB001388 Synaptobrevin

    UniProtKB/Swiss-Prot: SC22A_HUMAN, Q96IW7
    Similarity: Belongs to the synaptobrevin family
    Similarity: Contains 1 longin domain


    Function
    for SEC22A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SC22A_HUMAN, Q96IW7
    Function: May be involved in vesicle transport between the ER and the Golgi complex (By similarity)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SEC22A
    8/24 QIAGEN miScript miRNA Assays for microRNAs that regulate SEC22A (see all 24):
    hsa-miR-30c hsa-miR-513a-5p hsa-miR-128 hsa-miR-30d hsa-miR-520a-5p hsa-miR-3133 hsa-miR-30a hsa-miR-1184
    SwitchGear 3'UTR luciferase reporter plasmid: SEC22A 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SEC22A (see all 7)
    OriGene shRNA RFP: SEC22A
    OriGene siRNA: SEC22A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEC22A

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for SEC22A

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC22A (see all 3)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SEC22A (NM_012430)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC22A 

    Cell Line
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    Search LifeMap BioReagents cell lines for SEC22A

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC22A

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity TAS8621431


    SEC22A for ontologies           About GeneDecksing



    Pathways & Interactions
    for SEC22A gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    		Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics1.00


    1 PharmGKB Pathway for SEC22A
        Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEC22A

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for SEC22A (Q96IW73 ENSP000003105214) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USO1O607633, ENSP000004116984I2D: score=1 STRING: ENSP00000411698
    STX5Q131903, ENSP000002941794I2D: score=1 STRING: ENSP00000294179
    DTX2Q86UW93I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0006888ER to Golgi vesicle-mediated transport IEA--
    GO:0015031protein transport IEA--


    SEC22A for ontologies           About GeneDecksing



    Drugs & Compounds
    for SEC22A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SEC22A
    Search CenterWatch for drugs/clinical trials and news about SEC22A / SC22A 

    Transcripts
    for SEC22A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SEC22A gene: 
    NM_012430.4  

    Unigene Cluster for SEC22A:

    SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
    Hs.477361  [show with all ESTs]
    Unigene Representative Sequence: NM_012430
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000477063 ENST00000466950 ENST00000492595 ENST00000473494 ENST00000481965
    ENST00000466519 ENST00000480631 ENST00000491366 ENST00000487572 ENST00000309934(uc003ege.3 uc003egf.3)


    miRNA
    Products:             		 OriGene 3'-UTR Clone: SEC22A
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SEC22A
    8/24 QIAGEN miScript miRNA Assays for microRNAs that regulate SEC22A (see all 24):
    hsa-miR-30c hsa-miR-513a-5p hsa-miR-128 hsa-miR-30d hsa-miR-520a-5p hsa-miR-3133 hsa-miR-30a hsa-miR-1184
    SwitchGear 3'UTR luciferase reporter plasmid: SEC22A 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SEC22A (see all 7)
    OriGene shRNA RFP: SEC22A
    OriGene siRNA: SEC22A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEC22A
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC22A (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC22A (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SEC22A (NM_012430)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SEC22A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC22A 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SEC22A
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC22A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC22A

    Additional cDNA sequence: 

    AF100749.1 AK057587.1 AK315771.1 BC007122.1 

    17 DOTS entries:

    DT.441363  DT.100672256  DT.410109  DT.100020694  DT.100746689  DT.415773  DT.91869435  DT.92414540 
    DT.95170950  DT.120879402  DT.120879412  DT.92424169  DT.100790068  DT.40239577  DT.40248204  DT.451716 
    DT.95256424 

    24/129 AceView cDNA sequences (see all 129):

    AA421925 BM553223 BU164950 R19437 BP378939 BX116818 BM832542 BC007122 
    CR606488 BI520336 AA700691 AW994428 AA705723 BV207411 R53145 BG191654 
    AI350461 BF316652 AL550651 AA780149 BI823224 AW994412 BX474041 AA988478 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SEC22A (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10a · 10b · 10c
    SP1:                                                                                -                       -           -                     
    SP2:                                                                                -                       -                                 
    SP3:              -     -     -     -                 -                             -                                                         
    SP4:              -     -     -     -                                               -                                                         
    SP5:              -     -     -     -                                                                                                         


    ECgene alternative splicing isoforms for SEC22A

    Expression
    for SEC22A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SEC22A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGACTATCAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SEC22A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SEC22A

    SOURCE GeneReport for Unigene cluster: Hs.477361
        SABiosciences Custom PCR Arrays for SEC22A
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC22A
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC22A

    Orthologs
    for SEC22A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SEC22A gene from 8/24 species (see all 24)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Sec22a1 , 5 SEC22 vesicle trafficking protein homologe A (S. cerevisiae)5
    SEC22 vesicle trafficking protein homolog A (S. cerevisiae)1    		 93.38(n)1
    96.74(a)1    		   16 (25.21 cM)5
    3177171  NM_133704.41  NP_598465.21 
     353111315 
    chicken
    (Gallus gallus)    		 Aves SEC22A1 SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 81.22(n)
    86.64(a)    		   424250  NM_001006526.1  NP_001006526.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SEC22A6
    		 --
    		 83(a)
    		 1 ↔ 1
    		 1(79578038-79589256)
    African clawed frog
    (Xenopus laevis)    		 Amphibia CA972893.12   -- 76.53(n)    CA972893.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BC049530.12   -- 72.16(n)   324832  BC049530.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea sec-226
    		 --
    		 21(a)
    		 1 → many
    		 X(1035543-1037064)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SEC226
    AT5G522706
    		 vesicle transport protein SEC22
    		 23(a)
    21(a)
    		 many ↔ many
    many ↔ many
    		 1(4010779-4013125)
    5(21221643-21222600)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 4)    		 25.3 kDa vesicle transport protein, putative, expr...
    25.3 kDa vesicle transport protein, putative, expr...
    (see all 4)    		 32(a)
    25(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 1(7436788-7442252)
    3(32904073-32908028)


    ENSEMBL Gene Tree for SEC22A (if available)
    TreeFam Gene Tree for SEC22A (if available) 

    Paralogs
    for SEC22A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SEC22A gene
    SEC22C2  
    2 SIMAP similar genes for SEC22A using alignment to 8 protein entries:     SC22A_HUMAN (see all proteins):
    SEC22B    SEC22C

    SEC22A for paralogs           About GeneDecksing



    Genomic Variants
    for SEC22A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1315 NCBI SNPs in SEC22A are shown (see all 1315)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs786612261,2
    		--122918928(+) TACTAA/TGTGAA 1 -- us2k10--------
    rs67802871,2
    		C,F,A,--122919006(+) TTCAGC/TGGCAT 1 -- us2k17Minor allele frequency- T:0.16NA WA CSA EA 250
    rs1503772771,2
    		--122919106(+) CCATG-/CCTGGC 1 -- us2k10--------
    rs1452732081,2
    		--122919193(+) ATCCAA/CCCCCG 1 -- us2k10--------
    rs98676301,2
    		C,F,--122919223(+) CTGGGG/ATTACA 1 -- us2k14Minor allele frequency- A:0.50NA WA CSA 8
    rs1876461521,2
    		--122919244(+) ATCGCA/GCCTGG 1 -- us2k10--------
    rs98502371,2
    		C,F,--122919272(+) TTATTT/CATTTC 1 -- us2k17Minor allele frequency- C:0.17NA WA CSA EA 366
    rs1437662331,2
    		--122919322(+) AATACA/GTTTAT 1 -- us2k10--------
    rs1915782621,2
    		--122919344(+) ATCTAA/GGACAA 1 -- us2k10--------
    rs613263911,2
    		C,--122919382(+) TGAACT/GCTAGA 1 -- us2k12Minor allele frequency- G:0.15WA 120

    HapMap Linkage Disequilibrium report for SEC22A (122920774 - 122992983 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SEC22A: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEC22A
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    Disorders / Diseases
    for SEC22A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SEC22A for disorders           About GeneDecksing

    OMIM gene information: 612442    OMIM disorders: --

    1 disease for SEC22A:    About MalaCards
    malaria

    Human Genome Epidemiology (HuGE) Navigator: SEC22A (1 document)

    Export disorders for SEC22A gene to outside databases

    Publications
    for SEC22A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SEC22A gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with SEC22A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    4. Hsec22c: a homolog of yeast Sec22p and mammalian rsec22a and msec22b/ERS-24. (PubMed id 9501016)1, 3 Tang B.L....Hong W. (1998)
    5. Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. (PubMed id 9094723)1, 3 Hay J.C....Scheller R.H. (1997)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    9. The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope. (PubMed id 17499046)1 Mancias J.D. and Goldberg J. (2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    External Searches for SEC22A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing SEC22A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26984 HGNC: 20260 AceView: SEC22L2 Ensembl:ENSG00000121542 euGenes: HUgn26984
    ECgene: SEC22A H-InvDB: SEC22A

    Other Databases showing SEC22A gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SEC22A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SEC22A Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SEC22A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SEC22A gene:
    Search GeneIP for patents involving SEC22A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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