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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEC16B Gene

protein-coding   GIFtS: 53
GCID: GC01M177896

SEC16 Homolog B (S. Cerevisiae)

(Previous name: leucine zipper transcription regulator 2)
(Previous symbol: LZTR2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
SEC16 Homolog B (S. Cerevisiae)1 2     RGPR-p1172 3
LZTR21 2 3 5     PGPR-p1172
Leucine Zipper Transcription Regulator 21 2 3     Protein SEC16 Homolog B2
RGPR2 3 5     Protein Transport Protein Sec16B2
SEC16S2 3 5     KIAA19283
Regucalcin Gene Promotor Region Related Protein1 2     SEC16 Homolog B3
Regucalcin Gene Promoter Region-Related Protein P1172 3     

External Ids:    HGNC: 303011   Entrez Gene: 898662   Ensembl: ENSG000001203417   OMIM: 6128555   UniProtKB: Q96JE73   

Export aliases for SEC16B gene to outside databases

Previous GC identifers: GC01M176166 GC01M149125


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SEC16B Gene:
SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic
reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 (PubMed 17192411)).(supplied by OMIM, Jun
2009)

GeneCards Summary for SEC16B Gene: 
SEC16B (SEC16 homolog B (S. cerevisiae)) is a protein-coding gene. Diseases associated with SEC16B include obesity, and hepatocellular carcinoma. An important paralog of this gene is ENSG00000254154.

UniProtKB/Swiss-Prot: SC16B_HUMAN, Q96JE7
Function: Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for
normal transitional endoplasmic reticulum (tER) organization

Gene Wiki entry for SEC16B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEC16B gene promoter:
         TBP   HFH-3   STAT5B   Pbx1a   POU3F1   Brachyury   FOXI1   CREB   deltaCREB   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSEC16B promoter sequence
   Search SABiosciences Chromatin IP Primers for SEC16B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC16B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q25.2   Ensembl cytogenetic band:  1q25.2   HGNC cytogenetic band: 1q25.2

SEC16B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEC16B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M177896:  view genomic region     (about GC identifiers)

Start:
177,893,091 bp from pter      End:
177,939,348 bp from pter
Size:
46,258 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SC16B_HUMAN, Q96JE7 (See protein sequence)
Recommended Name: Protein transport protein Sec16B  
Size: 1060 amino acids; 116604 Da
Subunit: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Golgi apparatus
membrane; Peripheral membrane protein (By similarity)
Secondary accessions: A3EYF1 Q5HYF6 Q8N7D6 Q96GX6
Alternative splicing: 3 isoforms:  Q96JE7-1   Q96JE7-2   Q96JE7-3   

Explore the universe of human proteins at neXtProt for SEC16B: NX_Q96JE7

Explore proteomics data for SEC16B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96JE7

  • SEC16B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SEC16B Protein Expression
    REFSEQ proteins: NP_149118.2  
    ENSEMBL proteins: 
     ENSP00000308339   ENSP00000431727   ENSP00000435101  

    Human Recombinant Protein Products for SEC16B: 
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    Novus Biologicals SEC16B Proteins
    Novus Biologicals SEC16B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    SEC16B for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR024880 Sec16
     IPR024340 Sec16_CCD

    Graphical View of Domain Structure for InterPro Entry Q96JE7

    ProtoNet protein and cluster: Q96JE7

    1 Blocks protein domain: IPB006162 Phosphopantetheine attachment site

    UniProtKB/Swiss-Prot: SC16B_HUMAN, Q96JE7
    Similarity: Belongs to the SEC16 family


    SEC16B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SC16B_HUMAN, Q96JE7
    Function: Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for
    normal transitional endoplasmic reticulum (tER) organization

    Phenotypes:
         2 GenomeRNAi human phenotypes for SEC16B:

     Increased G1 DNA content  Increased circadian period len 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Sec16b):
     homeostasis/metabolism 

    SEC16B for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SEC16B 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SEC16B 
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    SwitchGear 3'UTR luciferase reporter plasmidSEC16B 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC16B


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEC16B

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for SEC16B (Q96JE73 ENSP000003083394) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SEC13P557353, ENSP000003121224I2D: score=3 STRING: ENSP00000312122
    PSMF1Q925303I2D: score=1 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007029endoplasmic reticulum organization IDA--
    GO:0007031peroxisome organization IDA--
    GO:0010628positive regulation of gene expression IMP--
    GO:0015031protein transport IEA--
    GO:0016559peroxisome fission IMP--

    SEC16B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SEC16B (SC16B)

    Search CenterWatch for drugs/clinical trials and news about SEC16B / SC16B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SEC16B gene: 
    NM_033127.2  

    Unigene Cluster for SEC16B:

    SEC16 homolog B (S. cerevisiae)
    Hs.149540  [show with all ESTs]
    Unigene Representative Sequence: NM_033127
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000441371 ENST00000495165 ENST00000308284 ENST00000327037 ENST00000526773
    ENST00000464631(uc001gll.4) ENST00000527976
    miRNA
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    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate SEC16B (see all 18):
    hsa-miR-199b-3p hsa-miR-539 hsa-miR-24-1* hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-24-2* hsa-miR-1244 hsa-miR-661
    SwitchGear 3'UTR luciferase reporter plasmidSEC16B 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC16B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC16B

    Additional mRNA sequence: 

    AB063357.1 AK074451.1 AK090971.1 AK093939.1 AK098627.1 AK314585.1 BC009106.1 BC108267.1 
    EF125213.1 

    8 DOTS entries:

    DT.95180203  DT.95267557  DT.100781524  DT.100023126  DT.121327632  DT.70103139  DT.95267560  DT.100652491 

    24/131 AceView cDNA sequences (see all 131):

    AI925437 BM717557 AA235749 AI950524 AA460256 AI804404 BX509870 BM471388 
    AX748374 AA336017 BX509240 AI431750 BP370620 AA235344 AK098627 AI553689 
    BM127583 AK093939 AW207501 AW137659 AA908484 AW294348 AW857326 AB063357 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for SEC16B (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^
    SP1:                                -     -     -     -     -     -           -     -     -     -                                                     -         
    SP2:                                                                                                                                                  -         
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                  -         
    SP5:                                                        -                                                                                                   

    ExUns: 22a · 22b ^ 23 ^ 24 ^ 25 ^ 26 ^ 27a · 27b ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39a · 39b · 39c · 39d ^ 40
    SP1:                          -                 -                                                                                                   
    SP2:                          -                 -                                                                                                   
    SP3:                                            -                                                     -                                             
    SP4:                          -                                                                                                                     
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for SEC16B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SEC16B expression in normal human tissues (normalized intensities)      SEC16B embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGGTGGCAC
    SEC16B Expression
    About this image


    SEC16B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Tooth (Integumentary System)    fully expand to see all 4 entries
             visceral organ/oral region/upper jaw   
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Thoracic Rib
             skeleton/cranium/viscerocranium   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             Meckel's Cartilage
             skeleton/cranium/viscerocranium   
     
     Neural Crest (Gastrulation Derivatives)
             skeleton/cranium/viscerocranium   
     
     Adipose (Muscoskeletal System)
             Mesenchymal Stem Cells Subcutaneous White Adipose

    See SEC16B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SEC16B

    SOURCE GeneReport for Unigene cluster: Hs.149540

    UniProtKB/Swiss-Prot: SC16B_HUMAN, Q96JE7
    Tissue specificity: Ubiquitous

        SABiosciences Custom PCR Arrays for SEC16B
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC16B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SEC16B gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sec16b1 , 5 SEC16 homolog B (S. cerevisiae)1, 5 80.09(n)1
    74.5(a)1
      1 (68.00 cM)5
    898671  NM_001159986.11  NP_001153458.11 
     1575067285 
    chicken
    (Gallus gallus)
    Aves SEC16B1 SEC16 homolog B (S. cerevisiae) 58.5(n)
    52.31(a)
      424431  NM_001031269.1  NP_001026440.1 
    lizard
    (Anolis carolinensis)
    Reptilia SEC16B6
    Uncharacterized protein
    65(a)
    1 ↔ 1
    GL343300.1(57305-116059)
    zebrafish
    (Danio rerio)
    Actinopterygii SEC16B6
    SEC16 homolog B (S. cerevisiae)
    27(a)
    1 ↔ 1
    6(20034682-20074894)
    fruit fly
    (Drosophila melanogaster)
    Insecta Sec166
    Sec16
    9(a)
    1 → many
    X(12490080-12503943)
    worm
    (Caenorhabditis elegans)
    Secernentea F13B9.16
    sec-166
    Uncharacterized protein ZK512.5
    9(a)
    12(a)
    many ↔ many
    many ↔ many
    X(8287261-8294515)
    III(9125839-9130810)


    ENSEMBL Gene Tree for SEC16B (if available)
    TreeFam Gene Tree for SEC16B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SEC16B gene
    ENSG000002541542  SEC16A2  
    3 SIMAP similar genes for SEC16B using alignment to 3 protein entries:     SC16B_HUMAN (see all proteins):
    FLJ00305    KIAA1928    SEC16A

    SEC16B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1091 SNPs in SEC16B are shown (see all 1091)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1878488611,2
    --177897796(+) ATTCCC/TCATTA 1 -- ds50010--------
    rs168521531,2
    C,F,H--177897850(+) AACCAT/CTATTA 1 -- ds500110Minor allele frequency- C:0.05NA NS EA 996
    rs1895892401,2
    --177897896(+) CTTCCC/TCTGTA 1 -- ds50010--------
    rs82231,2
    C,F,A,H--177897959(+) ATCAAC/TATCAG 1 -- ds500129Minor allele frequency- T:0.38MN NA NS EA WA CSA 2661
    rs80301,2
    C,F,A,H--177897975(+) TAGAAC/TATTAA 1 -- ds5001 ese335Minor allele frequency- T:0.36MN NA EA NS WA CSA 3575
    rs1822069481,2
    --177897982(+) TTAACA/GTACTA 1 -- ds50010--------
    rs1880459061,2
    --177897993(+) AACCTA/GTATTT 1 -- ds50010--------
    rs1926681741,2
    --177897994(+) ACCTGA/TATTTA 1 -- ds50010--------
    rs120274261,2
    C,H--177898116(+) AAGACG/ACCCCC 1 -- ds5001 ese34Minor allele frequency- A:0.00NS EA 416
    rs1487412381,2
    --177898352(+) GCCACA/GTGCCA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SEC16B (177893091 - 177939348 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SEC16B:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2719829CNV Deletion23290073
    esv2663986CNV Deletion23128226

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612855    OMIM disorders: --

    2 diseases for SEC16B:    About MalaCards
    obesity    hepatocellular carcinoma


    SEC16B for disorders           About GeneDecksing

    Genetic Association Database (GAD): SEC16B
    Human Genome Epidemiology (HuGE) Navigator: SEC16B (15 documents)

    Export disorders for SEC16B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SEC16B gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with SEC16B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and sequencing of the cDNA coding for a novel regucalcin gene promoter region-related protein in rat, mouse and human liver. (PubMed id 11605020)1, 2, 3, 9 Misawa H. and Yamaguchi M. (2001)
    2. Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide assoc iation studies. (PubMed id 20724581)1, 4 den Hoed M....Loos R.J. (2010)
    3. Cumulative effects and predictive value of common obe sity-susceptibility variants identified by genome-wide association studies. (PubMed id 19812171)1, 4 Li S....Loos R.J. (2010)
    4. Implication of genetic variants near NEGR1, SEC16B, T MEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, a nd KCTD15 with obesity and type 2 diabetes in 7705 Chinese. (PubMed id 20215397)1, 4 Ng M.C....Ma R.C. (2010)
    5. Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1, 4 MelAcn E....Lasky-Su J. (2010)
    6. Thirty new loci for age at menarche identified by a m eta-analysis of genome-wide association studies. (PubMed id 21102462)1, 4 Elks C.E....Murray A. (2010)
    7. Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collabora tive study. (PubMed id 20712903)1, 4 Morgan A.R....Mitchell E.A. (2010)
    8. Evaluation of genetic susceptibility loci for obesity in Chinese women. (PubMed id 20616199)1, 4 Shi J....Shu X.O. (2010)
    9. Association between obesity and polymorphisms in SEC1 6B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. (PubMed id 19851340)1, 4 Hotta K....Nakamura Y. (2009)
    10. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (PubMed id 19079260)1, 4 Thorleifsson G....Stefansson K. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 89866 HGNC: 30301 AceView: RGPR Ensembl:ENSG00000120341 euGenes: HUgn89866
    ECgene: SEC16B H-InvDB: SEC16B

    (According to HUGE)
    About This Section
    HUGE: KIAA1928

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SEC16B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SEC16B gene:
    Search GeneIP for patents involving SEC16B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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