Aliases for SEC16A Gene
External Ids for SEC16A Gene
Previous HGNC Symbols for SEC16A Gene
Previous GeneCards Identifiers for SEC16A Gene
This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013]
GeneCards Summary for SEC16A Gene
SEC16A (SEC16 Homolog A, Endoplasmic Reticulum Export Factor) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Vesicle-mediated transport. An important paralog of this gene is SEC16B.
UniProtKB/Swiss-Prot for SEC16A Gene
Defines endoplasmic reticulum exit sites (ERES) and is required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for normal transitional endoplasmic reticulum (tER) organization.