SEC14L5 Gene
protein-coding GIFtS: 41
GCID: GC16P005008
|
|
SEC14-like 5 (S. cerevisiae)
| |
Aliases
for SEC14L5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SEC14-Like 5 (S. Cerevisiae)1 2 | | PRELID4B1 2 | | KIAA04201 3 | | SEC14-Like Protein 52 |
Export aliases for SEC14L5 gene to outside databasesPrevious GC identifer: GC16P004932 |
Summaries
for SEC14L5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SEC14L5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SEC14L5 gene promoter:
MAZR NF-AT NF-AT2 POU2F1 POU2F1b POU2F1a NF-AT3 ARP-1 POU2F1c NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SEC14L5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC14L5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3SEC14L5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P005008: view genomic region
(about GC identifiers)
Start:
|
5,008,318 bp from pter |
End:
|
5,069,159 bp from pter |
Size:
|
60,842 bases |
Orientation:
|
plus strand |
|
Proteins
for SEC14L5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: S14L5_HUMAN, O43304 (See
protein sequence)Recommended Name: SEC14-like protein 5 Size: 696 amino acids; 78942 Da
Sequence caution: Sequence=BAA24850.2; Type=Erroneous initiation;Explore the universe of human proteins at neXtProt for SEC14L5: NX_O43304
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43304
SEC14L5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055507.1
ENSEMBL proteins: ENSP00000251170 ENSP00000468423
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
SEC14L5 for ontologies About GeneDecksing
SEC14L5 Antibody Products:
Assay Products for SEC14L5: |
Protein
Domains /
Families
for SEC14L5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SEC14L5 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43304ProtoNet protein and cluster: O43304 4 Blocks protein families: IPB001071 Cellular retinaldehyde-binding protein signature IPB001251 Cellular retinaldehyde-binding (CRAL)/Triple function domain (TRIO) IPB006797 MSF1-like conserved region IPB008273 Cellular retinaldehyde-binding/triple function
UniProtKB/Swiss-Prot: S14L5_HUMAN, O43304Similarity: Contains 1 CRAL-TRIO domainSimilarity: Contains 1 GOLD domainSimilarity: Contains 1 PRELI/MSF1 domain |
Function
for SEC14L5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC14L5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC14L5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SEC14L5 (NM_014692) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SEC14L5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC14L5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC14L5 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005215 | transporter activity |
IEA | -- |
SEC14L5 for ontologies About GeneDecksing
|
Pathways & Interactions
for SEC14L5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEC14L5
|
Drugs & Compounds
for SEC14L5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SEC14L5
Search CenterWatch for drugs/clinical trials and news about SEC14L5 / S14L5
|
Transcripts
for SEC14L5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SEC14L5 gene: NM_014692.1 Unigene Cluster for SEC14L5: SEC14-like 5 (S. cerevisiae) Hs.512856 [show with all ESTs]Unigene Representative Sequence: NM_0146922 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000251170(uc002cye.2) ENST00000587469
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC14L5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC14L5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SEC14L5 (NM_014692) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SEC14L5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC14L5 |
Additional cDNA sequence: AB007880.2 BC045685.1 1 DOTS entry: DT.111637 24/242 AceView cDNA sequences (see all 242): CF132471 AI802901 AA680361 BM791409 CR619322 CA495409 CB124924 AI371094 NM_019109 AA700910 BM725132 AI273221 BM801720 H42894 BX376384 CB158360 AA380399 CA391104 AY359073 BM852978 BM559894 BF438369 AL539861 BQ935553
GeneLoc Exon Structure
|
Expression
for SEC14L5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SEC14L5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SEC14L5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SEC14L5
SOURCE GeneReport for Unigene cluster: Hs.512856
SABiosciences Custom PCR Arrays for SEC14L5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SEC14L5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SEC14L5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC14L5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC14L5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC14L5 |
Orthologs
for SEC14L5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SEC14L5 gene from 8/19 species (see all 19) About this table
ENSEMBL Gene Tree for SEC14L5 (if available)
TreeFam Gene Tree for SEC14L5 (if available) |
Paralogs
for SEC14L5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SEC14L5 gene
- ENSG000002495902 SEC14L12 SEC14L62 SEC14L22 SEC14L32 SEC14L42
6 SIMAP similar genes for SEC14L5 using alignment to 2 protein entries: S14L5_HUMAN (see all proteins):SEC14L1 DKFZp686C06176 SEC14L2 SEC14L3 SEC14L4 Em
SEC14L5 for paralogs About GeneDecksing
|
Genomic Variants
for SEC14L5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SEC14L5 (5008318 - 5069159 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for SEC14L5
7 CNVs: 9755 32078 8811 5436 3101 3989 72444 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEC14L5 |
|
Disorders
/ Diseases
for SEC14L5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for SEC14L5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SEC14L5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SEC14L5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2, 3 Ishikawa K....Ohara O. (1997)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)2 Nakajima D.... Nagase T. (2002)
|
External Searches for SEC14L5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SEC14L5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SEC14L5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SEC14L5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SEC14L5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SEC14L5 gene:
Search GeneIP for patents involving SEC14L5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SEC14L5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SEC14L5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SEC14L5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SEC14L5 | | | OriGene Protein Over-expression Lysate for SEC14L5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SEC14L5 | | OriGene 3'-UTR Clone for SEC14L5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC14L5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC14L5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SEC14L5 | | OriGene Custom Protein Services for SEC14L5 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SEC14L5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEC14L5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC14L5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEC14L5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC14L5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC14L5 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SEC14L5 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | SEC14L5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC14L5 |
|  |  |  | | | | Search ThermoFisher Antibodies for SEC14L5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC14L5 |
|
|
|
|
