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Aliases for SEC11B Gene

Aliases for SEC11B Gene

  • SEC11 Homolog B, Pseudogene (S. Cerevisiae) 2 3
  • SEC11L2 3 4
  • SPCS4B 3 4
  • SEC11 Homolog B (S. Cerevisiae) 2
  • SEC11-Like 2 (S. Cerevisiae) 2
  • SEC11 Homolog A Pseudogene 3
  • SEC11-Like Protein 2 4
  • SEC11 Homolog B 4
  • SEC11-Like 2 3
  • EC 3.4.21.89 4

External Ids for SEC11B Gene

Previous HGNC Symbols for SEC11B Gene

  • SEC11L2

Previous GeneCards Identifiers for SEC11B Gene

  • GC08M055599
  • GC08M055436
  • GC08M050903

Summaries for SEC11B Gene

GeneCards Summary for SEC11B Gene

SEC11B (SEC11 Homolog B, Pseudogene (S. Cerevisiae)) is a Pseudogene. Diseases associated with SEC11B include dengue shock syndrome. GO annotations related to this gene include serine-type peptidase activity.

UniProtKB/Swiss-Prot for SEC11B Gene

  • Putative component of some signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SEC11B Gene

Genomics for SEC11B Gene

Genomic Location for SEC11B Gene

Start:
54,522,490 bp from pter
End:
54,523,381 bp from pter
Size:
892 bases
Orientation:
Minus strand

Genomic View for SEC11B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SEC11B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SEC11B Gene

No data available for Regulatory Elements for SEC11B Gene

Proteins for SEC11B Gene

  • Protein details for SEC11B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7V7-SC11B_HUMAN
    Recommended name:
    Putative signal peptidase complex catalytic subunit SEC11B
    Protein Accession:
    P0C7V7
    Secondary Accessions:

    Protein attributes for SEC11B Gene

    Size:
    166 amino acids
    Molecular mass:
    19160 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SEC11B Gene

Proteomics data for SEC11B Gene at MOPED

Post-translational modifications for SEC11B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SEC11B Gene

Domains for SEC11B Gene

Protein Domains for SEC11B Gene

Suggested Antigen Peptide Sequences for SEC11B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7V7

UniProtKB/Swiss-Prot:

SC11B_HUMAN :
  • P0C7V7
Family:
  • Belongs to the peptidase S26B family.
genes like me logo Genes that share domains with SEC11B: view

No data available for Gene Families for SEC11B Gene

Function for SEC11B Gene

Molecular function for SEC11B Gene

UniProtKB/Swiss-Prot CatalyticActivity:
Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins
UniProtKB/Swiss-Prot Function:
Putative component of some signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

Enzyme Numbers (IUBMB) for SEC11B Gene

Gene Ontology (GO) - Molecular Function for SEC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008236 serine-type peptidase activity IEA --
genes like me logo Genes that share ontologies with SEC11B: view

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SEC11B Gene

Localization for SEC11B Gene

Subcellular locations from UniProtKB/Swiss-Prot for SEC11B Gene

Membrane; Single-pass type II membrane protein.

Gene Ontology (GO) - Cellular Components for SEC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SEC11B: view

No data available for Subcellular locations from COMPARTMENTS for SEC11B Gene

Pathways for SEC11B Gene

SuperPathways for SEC11B Gene

No Data Available

Interacting Proteins for SEC11B Gene

Gene Ontology (GO) - Biological Process for SEC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006465 signal peptide processing IEA --
genes like me logo Genes that share ontologies with SEC11B: view

No data available for Pathways by source for SEC11B Gene

Transcripts for SEC11B Gene

mRNA/cDNA for SEC11B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SEC11B Gene

No ASD Table

Relevant External Links for SEC11B Gene

GeneLoc Exon Structure for
SEC11B
ECgene alternative splicing isoforms for
SEC11B

Expression for SEC11B Gene

mRNA expression in normal human tissues for SEC11B Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SEC11B Gene

genes like me logo Genes that share expressions with SEC11B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for SEC11B Gene

Orthologs for SEC11B Gene

Evolution for SEC11B Gene

ENSEMBL:
Gene Tree for SEC11B (if available)
TreeFam:
Gene Tree for SEC11B (if available)

No data available for Orthologs for SEC11B Gene

Paralogs for SEC11B Gene

Selected SIMAP similar genes for SEC11B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SEC11B: view

No data available for Paralogs for SEC11B Gene

Variants for SEC11B Gene

Relevant External Links for SEC11B Gene

HapMap Linkage Disequilibrium report
SEC11B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for SEC11B Gene

Disorders for SEC11B Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for SEC11B Gene in MalaCards »

(1) Diseases for SEC11B Gene including...

Relevant External Links for SEC11B

Genetic Association Database (GAD)
SEC11B
genes like me logo Genes that share disorders with SEC11B: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SEC11B Gene

Publications for SEC11B Gene

  1. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  2. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PMID: 21987572) Lee K.A. … Doedens J.R. (J. Biol. Chem. 2011) 3
  3. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. (PMID: 17903303) O'Donnell C.J. … Demissie S. (BMC Med. Genet. 2007) 48
  4. Susceptibility loci for intracranial aneurysm in European and Japanese populations. (PMID: 18997786) Bilguvar K. … GA1nel M. (Nat. Genet. 2008) 48
  5. Genome-wide association study of intracranial aneurysm identifies three new risk loci. (PMID: 20364137) Yasuno K. … GA1nel M. (Nat. Genet. 2010) 48

Products for SEC11B Gene

Sources for SEC11B Gene

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