Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SEC11B Gene

Aliases for SEC11B Gene

  • SEC11 Homolog B, Signal Peptidase Complex Subunit, Pseudogene 2 3
  • SEC11L2 3 4
  • SPCS4B 3 4
  • SEC11 Homolog B, Pseudogene (S. Cerevisiae) 2
  • SEC11 Homolog B (S. Cerevisiae) 2
  • SEC11-Like 2 (S. Cerevisiae) 2
  • SEC11 Homolog B, Pseudogene 3
  • SEC11 Homolog A Pseudogene 3
  • SEC11-Like Protein 2 4
  • SEC11 Homolog B 4
  • SEC11-Like 2 3
  • EC 3.4.21.89 4

External Ids for SEC11B Gene

Previous HGNC Symbols for SEC11B Gene

  • SEC11L2

Previous GeneCards Identifiers for SEC11B Gene

  • GC08M055599
  • GC08M055436
  • GC08M050903

Summaries for SEC11B Gene

GeneCards Summary for SEC11B Gene

SEC11B (SEC11 Homolog B, Signal Peptidase Complex Subunit, Pseudogene) is a Pseudogene. GO annotations related to this gene include serine-type peptidase activity.

UniProtKB/Swiss-Prot for SEC11B Gene

  • Putative component of some signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SEC11B Gene

Genomics for SEC11B Gene

Genomic Location for SEC11B Gene

Chromosome:
8
Start:
54,522,490 bp from pter
End:
54,523,381 bp from pter
Size:
892 bases
Orientation:
Minus strand

Genomic View for SEC11B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for SEC11B Gene

No data available for Regulatory Elements for SEC11B Gene

Proteins for SEC11B Gene

  • Protein details for SEC11B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7V7-SC11B_HUMAN
    Recommended name:
    Putative signal peptidase complex catalytic subunit SEC11B
    Protein Accession:
    P0C7V7

    Protein attributes for SEC11B Gene

    Size:
    166 amino acids
    Molecular mass:
    19160 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SEC11B Gene

Proteomics data for SEC11B Gene at MOPED

Post-translational modifications for SEC11B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SEC11B Gene

Domains & Families for SEC11B Gene

Protein Domains for SEC11B Gene

Suggested Antigen Peptide Sequences for SEC11B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7V7

UniProtKB/Swiss-Prot:

SC11B_HUMAN :
  • Belongs to the peptidase S26B family.
Family:
  • Belongs to the peptidase S26B family.
genes like me logo Genes that share domains with SEC11B: view

No data available for Gene Families for SEC11B Gene

Function for SEC11B Gene

Molecular function for SEC11B Gene

UniProtKB/Swiss-Prot CatalyticActivity:
Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins
UniProtKB/Swiss-Prot Function:
Putative component of some signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

Enzyme Numbers (IUBMB) for SEC11B Gene

Gene Ontology (GO) - Molecular Function for SEC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008236 serine-type peptidase activity IEA --
genes like me logo Genes that share ontologies with SEC11B: view

Animal Model Products

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SEC11B Gene

Localization for SEC11B Gene

Subcellular locations from UniProtKB/Swiss-Prot for SEC11B Gene

Membrane; Single-pass type II membrane protein.

Gene Ontology (GO) - Cellular Components for SEC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SEC11B: view

No data available for Subcellular locations from COMPARTMENTS for SEC11B Gene

Pathways & Interactions for SEC11B Gene

SuperPathways for SEC11B Gene

No Data Available

Interacting Proteins for SEC11B Gene

Gene Ontology (GO) - Biological Process for SEC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006465 signal peptide processing IEA --
genes like me logo Genes that share ontologies with SEC11B: view

No data available for Pathways by source and SIGNOR curated interactions for SEC11B Gene

Drugs & Compounds for SEC11B Gene

No Compound Related Data Available

Transcripts for SEC11B Gene

mRNA/cDNA for SEC11B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SEC11B Gene

No ASD Table

Relevant External Links for SEC11B Gene

GeneLoc Exon Structure for
SEC11B
ECgene alternative splicing isoforms for
SEC11B

Expression for SEC11B Gene

mRNA expression in normal human tissues for SEC11B Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for SEC11B Gene



genes like me logo Genes that share expression patterns with SEC11B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SEC11B Gene

Orthologs for SEC11B Gene

Evolution for SEC11B Gene

ENSEMBL:
Gene Tree for SEC11B (if available)
TreeFam:
Gene Tree for SEC11B (if available)

No data available for Orthologs for SEC11B Gene

Paralogs for SEC11B Gene

(4) SIMAP similar genes for SEC11B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SEC11B: view

No data available for Paralogs for SEC11B Gene

Variants for SEC11B Gene

Relevant External Links for SEC11B Gene

HapMap Linkage Disequilibrium report
SEC11B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SEC11B Gene

Disorders for SEC11B Gene

Relevant External Links for SEC11B

Genetic Association Database (GAD)
SEC11B
genes like me logo Genes that share disorders with SEC11B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SEC11B Gene

Publications for SEC11B Gene

  1. Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. (PMID: 22001756) Khor C.C. … Simmons C.P. (Nat. Genet. 2011) 67
  2. Genome-wide association study of intracranial aneurysm identifies three new risk loci. (PMID: 20364137) Yasuno K. … GA1nel M. (Nat. Genet. 2010) 67
  3. Susceptibility loci for intracranial aneurysm in European and Japanese populations. (PMID: 18997786) Bilguvar K. … GA1nel M. (Nat. Genet. 2008) 67
  4. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. (PMID: 17903303) O'Donnell C.J. … Demissie S. (BMC Med. Genet. 2007) 67
  5. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 67

Products for SEC11B Gene

Sources for SEC11B Gene

Back to Top

Content