SEC11A Gene
protein-coding GIFtS: 53
GCID: GC15M085212
|
|
SEC11 homolog A (S. cerevisiae)(Previous name: SEC11-like 1 (S. cerevisiae) ) (Previous symbol: SEC11L1)
| |
Aliases for SEC11A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| SEC11 Homolog A (S. Cerevisiae)1 2 | | SPase 18 KDa Subunit2 3 | | SEC11L11 2 3 | | SEC11-Like 1 (S. Cerevisiae)1 | | SPC181 2 3 | | 1810012E07Rik2 | | SPCS4A1 2 3 | | Signal Peptidase Complex (18kD)2 | | Sid28951 | | Signal Peptidase Complex Catalytic Subunit SEC11A2 | | Endopeptidase SP182 3 | | EC 3.4.21.893 | | Microsomal Signal Peptidase 18 KDa Subunit2 3 | | SEC11 Homolog A3 | | SEC11-Like Protein 12 3 | | |
Export aliases for SEC11A gene to outside databasesPrevious GC identifer: GC15M083015 |
Summaries for SEC11A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SEC11A: This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signalpeptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis.Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome8. (provided by RefSeq, Dec 2012) UniProtKB/Swiss-Prot: SC11A_HUMAN, P67812Function: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins asthey are translocated into the lumen of the endoplasmic reticulum (By similarity)
|
Genomic Views for SEC11A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SEC11A gene promoter: STAT1 AP-1 STAT1beta c-Ets-1 Arnt STAT1alpha PPAR-gamma1 POU2F1 POU2F1a PPAR-gamma2 Other transcription factors
Search SABiosciences Chromatin IP Primers for SEC11A
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC11A |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q25.3 Ensembl cytogenetic band: 15q25.3 HGNC cytogenetic band: 15q25.2SEC11A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M085212: view genomic region
(about GC identifiers)
Start:
|
85,212,775 bp from pter |
End:
|
85,259,947 bp from pter |
Size:
|
47,173 bases |
Orientation:
|
minus strand |
|
Proteins for SEC11A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SC11A_HUMAN, P67812 (See
protein sequence)Recommended Name: Signal peptidase complex catalytic subunit SEC11A Size: 179 amino acids; 20625 Da
Subunit: Component of the microsomal signal peptidase complex which consists of five members: SEC11A, SEC11C, SPCS1,SPCS2 and SPCS3 (By similarity)
Subcellular location: Microsome membrane; Single-pass type II membrane protein (By similarity). Endoplasmic reticulummembrane; Single-pass type II membrane protein (By similarity)
Secondary accessions: B2RAD7 O75957 P21378 Q53FQ8Explore the universe of human proteins at neXtProt for SEC11A: NX_P67812
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P67812 SEC11A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001258847.1 NP_001258848.1 NP_001258849.1 NP_001258850.1 NP_001258851.1 NP_055115.1 ENSEMBL proteins: ENSP00000452697 ENSP00000452684 ENSP00000268220 ENSP00000453930 ENSP00000413121 ENSP00000453997 ENSP00000452932 ENSP00000454193 Reactome Protein details: P67812 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SEC11A for ontologies About GeneDecksing
SEC11A Antibody Products: Assay Products for SEC11A: |
Protein
Domains / Families for SEC11A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SEC11A for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry P67812ProtoNet protein and cluster: P67812 2 Blocks protein families: IPB000223 Bacterial leader peptidase 1 (S26) family signature IPB001733 Eukaryotic signal peptidase (S27) family signature
UniProtKB/Swiss-Prot: SC11A_HUMAN, P67812Similarity: Belongs to the peptidase S26B family |
Function for SEC11A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SC11A_HUMAN, P67812Function: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins asthey are translocated into the lumen of the endoplasmic reticulum (By similarity)Catalytic activity: Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmicproteinsEnzyme Number (IUBMB): EC 3.4.21.891
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC11A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC11A (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SEC11A (NM_014300) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SEC11A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC11A  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC11A |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008236 | serine-type peptidase activity |
IEA | -- |
SEC11A for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SEC11A: Animal Models: 1 MGI phenotypic allele for Sec11a (no phenotypes)
SEC11A for phenotypes About GeneDecksing
|
Pathways & Interactions for SEC11A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | | | 2 | Synthesis of PB1-F2 | | | 3 | Protein export | | | 4 | Generic Transcription Pathway | | | 5 | Insulin Processing | |
Pathway sources See GeneCards unified pathways Show all pathways
5/9
Reactome Pathways for SEC11A (see all 9)
1
Kegg Pathway (Kegg details for SEC11A):
SEC11A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEC11A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/96 Interacting proteins for SEC11A (P678122, 3 ENSP000002682204) via UniProtKB, MINT, STRING, and/or I2D (see all 96)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006112 | energy reserve metabolic process |
TAS | -- | | GO:0006412 | translation |
TAS | -- | | GO:0006465 | signal peptide processing |
IEA | -- | | GO:0006508 | proteolysis |
IEA | -- | | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane |
TAS | -- |
SEC11A for ontologies About GeneDecksing
|
Drugs & Compounds for SEC11A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SEC11A Search CenterWatch for drugs/clinical trials and news about SEC11A / SC11A 
|
Transcripts for SEC11A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SEC11A gene (6 alternative transcripts): NM_001271918.1 NM_001271919.1 NM_001271920.1 NM_001271921.1 NM_001271922.1 NM_014300.3 Unigene Cluster for SEC11A: SEC11 homolog A (S. cerevisiae) Hs.9534 [show with all ESTs]Unigene Representative Sequence: CR74965610 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000559376 ENST00000558134 ENST00000560266 ENST00000268220(uc002blb.1 uc002blc.1) ENST00000558217 ENST00000558924 ENST00000455959 ENST00000560409 ENST00000559729 ENST00000558196
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC11A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC11A (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SEC11A (NM_014300) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SEC11A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC11A  |
Additional cDNA sequence: AF061737.1 AF087906.1 AF090315.1 AF108945.1 AK223224.1 AK300693.1 AK314146.1 BC000359.2 BC014508.1 CR457127.1 CR749656.1 NR_073518.1 17 DOTS entries: DT.102828840 DT.418953 DT.100840712 DT.121014038 DT.75177571 DT.100840699 DT.100840709 DT.101987980 DT.95081982 DT.99976862 DT.100840700 DT.100840702 DT.101963682 DT.92460461 DT.121014076 DT.92460465 DT.40247520 24/595 AceView cDNA sequences (see all 595): AA621892 BQ285919 CR599809 BX377158 AI335664 BQ717650 CR609347 CR591824 CK822810 BC014508 NM_014300 CD369855 NM_021077 BM985046 W92942 AA151795 CR593030 BQ015654 CD677029 BU685949 BM726003 BM991221 CB305558 AI283673 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SEC11A (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | |
| SP1: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SEC11A
|
Expression for SEC11A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SEC11A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TGCACCACAG
About this image See SEC11A Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SEC11A
SOURCE GeneReport for Unigene cluster: Hs.9534 SABiosciences Custom PCR Arrays for SEC11A
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SEC11A Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SEC11A | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC11A | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC11A | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC11A |
Orthologs for SEC11A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SEC11A gene from 10/35 species (see all 35) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Sec11a1 , 5 |
SEC11 homolog A (S. cerevisiae)1, 5 |
90.88(n)1 99.44(a)1 |
  |
7 (45.71 cM)5 565291 NM_019951.11 NP_064335.11 809048895 |
chicken (Gallus gallus) |
Aves |
SEC11A1 |
SEC11 homolog A (S. cerevisiae) |
82.12(n) 97.77(a) |
  |
415334 NM_001005802.1 NP_001005802.1 |
lizard (Anolis carolinensis) |
Reptilia |
SEC11A6 |
-- |
90(a) |
1 ↔ 1 |
GL343490.1(205617-213605) |
African clawed frog (Xenopus laevis) |
Amphibia |
CF282622.12 |
-- |
78.98(n) |
  |
CF282622.1 |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.74722 |
Transcribed sequence with strong similarity to protein more |
80.76(n) |
  |
CK361126.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
twr6 |
twisted bristles roughened eye |
72(a) |
1 ↔ 1 |
3R(2483604-2485164) |
worm (Caenorhabditis elegans) |
Secernentea |
Y54E10BR.56 |
Protein Y54E10BR.5 |
68(a) |
1 → many |
I(3028329-3031096) |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
SEC11(YIR022W)4 SEC111 |
18kDa catalytic subunit of the Signal Peptidase Complex more4 Sec11p1 |
53.41(n)1 48.19(a)1 |
  |
9(398733-399236)4 8548401, 4 NP_012288.11, 4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT1G526001 |
signal peptidase, endoplasmic reticulum-type |
60.66(n) 57.56(a) |
  |
841692 NM_104138.4 NP_175669.1 |
rice (Oryza sativa) |
Liliopsida |
Os06g02738001 |
hypothetical protein |
61.88(n) 58.62(a) |
  |
4340738 NM_001063906.1 NP_001057371.1 |
ENSEMBL Gene Tree for SEC11A (if available) TreeFam Gene Tree for SEC11A (if available)  |
Paralogs for SEC11A gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SEC11A gene
- SEC11C2
5 SIMAP similar genes for SEC11A using alignment to 7 protein entries: SC11A_HUMAN (see all proteins):SPC18 SEC11L3 SEC11L1 SEC11C SEC11B
SEC11A for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for SEC11A PGOHUM00000262016
|
Genomic Variants for SEC11A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 15 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SEC11A (85212775 - 85259947 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SEC11A: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEC11A |
|
Disorders
/ Diseases for SEC11A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SEC11A for disorders About GeneDecksing
1 disease for SEC11A: About MalaCardsmalaria Export disorders for SEC11A gene to outside databases
|
Publications for SEC11A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SEC11A gene, integrated from 9 sources (see all 29): (articles sorted by number of sources associating them with SEC11A) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Shotgun proteomics and network analysis of ubiquitin-r elated proteins from human breast carcinoma epithelial cells. (PubMed id 21853274)1 Zhou J....Liang S. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Transcriptome dissection of gastric cancer: identification of novel diagnostic and therapeutic targets from pathology specimens. (PubMed id 19261089)1 Yasui W....Motoshita J. (2009)
- Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1 Meierhofer D.... Kaiser P. (2008)
- Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
|
External Searches for SEC11A gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SEC11A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SEC11A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SEC11A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SEC11A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SEC11A gene: Search GeneIP for patents involving SEC11A
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SEC11A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SEC11A | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SEC11A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SEC11A | | OriGene Protein Over-expression Lysate for SEC11A | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SEC11A | | OriGene 3'-UTR Clone for SEC11A | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEC11A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEC11A | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SEC11A | | OriGene Custom Protein Services for SEC11A | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SEC11A | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEC11A | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEC11A | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEC11A | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEC11A | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEC11A |
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| | | Search Tocris compounds for SEC11A |
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 | | SEC11A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEC11A |
|  |  |  | | | Search ThermoFisher Antibodies for SEC11A |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEC11A |
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