Aliases for SDS Gene
External Ids for SDS Gene
Previous GeneCards Identifiers for SDS Gene
This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008]
GeneCards Summary for SDS Gene
SDS (Serine Dehydratase) is a Protein Coding gene. Diseases associated with SDS include shwachman-diamond syndrome and aplastic anemia. Among its related pathways are Carbon metabolism and Sulfur amino acid metabolism. GO annotations related to this gene include protein homodimerization activity and L-serine ammonia-lyase activity. An important paralog of this gene is SDSL.