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SDPR Gene

protein-coding   GIFtS: 54
GCID: GC02M192663

Serum Deprivation Response

(Previous names: serum deprivation response (phosphatidylserine-binding protein),...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Serum Deprivation Response1 2     Serum Deprivation Response (Phosphatidylserine-Binding Protein)1
Phosphatidylserine Binding Protein1 2     CAVIN22
Phosphatidylserine-Binding Protein2 3     cavin-22
PS-p682 3     Serum Deprivation-Response Protein2
SDR2 5     Cavin-23
Serum Deprivation Response (Phosphatidylserine Binding Protein)1     

External Ids:    HGNC: 106901   Entrez Gene: 84362   Ensembl: ENSG000001684977   OMIM: 6067285   UniProtKB: O958103   

Export aliases for SDPR gene to outside databases

Previous GC identifers: GC02M190880 GC02M191402 GC02M192902 GC02M192525 GC02M192407 GC02M184557


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SDPR Gene:
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved
cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and
transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its
over-expression results in caveolae deformation and membrane tubulation.(provided by RefSeq, Sep 2009)

GeneCards Summary for SDPR Gene:
SDPR (serum deprivation response) is a protein-coding gene. Diseases associated with SDPR include spondylolisthesis, and quadriplegia. GO annotations related to this gene include phospholipid binding and phosphatidylserine binding. An important paralog of this gene is PRKCDBP.

UniProtKB/Swiss-Prot: SDPR_HUMAN, O95810
Function: May play a role in targeting PRKCA to caveolae (By similarity)

Gene Wiki entry for SDPR Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the SDPR gene promoter:
         HOXA9B   HOXA9   HOXA3   Pax-5   CUTL1   POU3F2   E47   Cart-1   Hand1   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSDPR promoter sequence
   Search Chromatin IP Primers for SDPR

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SDPR


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q32-q33   Ensembl cytogenetic band:  2q32.3   HGNC cytogenetic band: 2q32-q33

SDPR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SDPR gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M192663:  view genomic region     (about GC identifiers)

Start:
192,699,028 bp from pter      End:
192,712,006 bp from pter
Size:
12,979 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SDPR_HUMAN, O95810 (See protein sequence)
Recommended Name: Serum deprivation-response protein  
Size: 425 amino acids; 47173 Da
Subunit: Binds to PRKCA in the presence of phosphatidylserine (By similarity). Interacts with MURC; this augments
the transactivation of NPPA by MURC
Miscellaneous: Binds phosphatidylserine (PS) in a calcium-independent manner. PS-binding is inhibited by
phosphotidic acid and phosphatidylinositol. Does not bind phosphatidylcholine

Explore the universe of human proteins at neXtProt for SDPR: NX_O95810

Explore proteomics data for SDPR at MOPED

Post-translational modifications: 

  • Phosphorylated on Ser residues1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SDPR Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004648.1  
    ENSEMBL proteins: 
     ENSP00000305675  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026752 Cavin_fam

    Graphical View of Domain Structure for InterPro Entry O95810

    ProtoNet protein and cluster: O95810

    UniProtKB/Swiss-Prot: SDPR_HUMAN, O95810
    Similarity: Belongs to the PTRF/SDPR family


    SDPR for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SDPR_HUMAN, O95810
    Function: May play a role in targeting PRKCA to caveolae (By similarity)
    Induction: Up-regulated in asyncronously growing fibroblasts following serum deprivation but not following contact
    inhibition. Down-regulated during synchronous cell cycle re-entry

         Genatlas biochemistry entry for SDPR:
    serum deprivation response gene,specifically induced during growth arrest as elicited by serum starvation but not
    in contact-inhibited fibroblasts,downregulated during GO/S transition,targetting of protein kinase alpha and
    delta to caveolae

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001786phosphatidylserine binding IDA10191091
    GO:0005515protein binding IPI19722192
    GO:0005543phospholipid binding TAS10191091
         
    SDPR for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Sdpr):
     adipose tissue  cardiovascular system  cellular  respiratory system 

    SDPR for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Sdprtm1(KOMP)Vlcg for SDPR

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SDPR
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SDPR
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SDPR

    miRNA
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    miRTarBase miRNAs that target SDPR:
    hsa-mir-1 (MIRT023867)

    Block miRNA regulation of human, mouse, rat SDPR using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SDPR (see all 10):
    hsa-miR-154 hsa-miR-206 hsa-miR-3673 hsa-miR-27a hsa-miR-513a-5p hsa-miR-1 hsa-miR-432 hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmidSDPR 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SDPR_HUMAN, O95810: Cytoplasm, cytosol. Membrane, caveola. Note=Colocalizes with CAV1 to caveolae
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    plasma membrane5
    golgi apparatus4
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA18332105
    GO:0005794Golgi apparatus ----
    GO:0005829cytosol IDA2390065
    GO:0005886plasma membrane ----
    GO:0005901caveola IEA--

    SDPR for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SDPR
    Interactions:

        GeneGlobe Interaction Network for SDPR

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for SDPR (O958101, 2, 3 ENSP000003056754) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLEKHF2Q9H8W42, 3, ENSP000003223734MINT-67941 I2D: score=5 STRING: ENSP00000322373
    CAV1Q031352, 3, ENSP000003391914MINT-7234712 I2D: score=1 STRING: ENSP00000339191
    PRKCDBPQ969G52, 3, ENSP000003072924MINT-7234727 I2D: score=1 STRING: ENSP00000307292
    PLEKP085671, 3, ENSP000002343134EBI-742141,EBI-2565501 I2D: score=1 STRING: ENSP00000234313
    NUDT18Q6ZVK82, 3, ENSP000003078524MINT-66244 I2D: score=5 STRING: ENSP00000307852
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SDPR

    Selected HMDB Compounds for SDPR (see all 504)    About this table
    CompoundSynonyms CAS #PubMed Ids
    PS(16:0/16:0)Phosphatidylserine (16:0/16:0) (see all 14)3036-82-612486725
    CalciumCa (see all 2)7440-70-2--
    PI(16:0/16:0)Phosphatidylinositol(32:0) (see all 8)----
    PI(16:0/16:1(9Z))Phosphatidylinositol(32:1) (see all 14)----
    PI(16:0/16:2(9Z,12Z))Phosphatidylinositol(16:0/16:2n4) (see all 18)----
    PI(16:0/18:0)Phosphatidylinositol(16:0/18:0) (see all 8)----
    PI(16:0/18:1(11Z))Phosphatidylinositol(16:0/18:1w7) (see all 14)----
    PI(16:0/18:1(9Z))Phosphatidylinositol(16:0/18:1) (see all 14)----
    PI(16:0/18:2(9Z,12Z))PIno(16:0/18:2) (see all 14)----
    PI(16:0/20:0)PI(16:0/20:0) (see all 8)----



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SDPR gene: 
    NM_004657.5  

    Unigene Cluster for SDPR:

    Serum deprivation response
    Hs.26530  [show with all ESTs]
    Unigene Representative Sequence: NM_004657
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000304141(uc002utb.3)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SDPR (see all 10):
    hsa-miR-154 hsa-miR-206 hsa-miR-3673 hsa-miR-27a hsa-miR-513a-5p hsa-miR-1 hsa-miR-432 hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmidSDPR 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SDPR
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      QuantiTect SYBR Green Assays in human, mouse, rat SDPR
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    Additional mRNA sequence: 

    AF085481.1 AK026943.1 AK290378.1 AK311055.1 BC016475.1 

    5 DOTS entries:

    DT.314257  DT.100780315  DT.40312658  DT.120973873  DT.100651923 

    Selected AceView cDNA sequences (see all 140):

    BP364618 CD619110 AI378981 AL597575 AA564136 AI986244 AA150400 AI568116 
    AU100074 AL597564 BM974509 AA676951 CB268675 AL577436 BQ002697 BC016475 
    NM_004657 AK026943 BX644670 BP373619 AI282599 AA487576 BM801354 AI287634 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SDPR    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3
    SP1:        -     -         
    SP2:                        


    ECgene alternative splicing isoforms for SDPR

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SDPR expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SDPR Expression
    About this image


    SDPR expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 12) fully expand
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Human umbilical vein endothelial cells (HUVEC)
             Endothelial-like cells
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Bone Marrow
     
     Heart (Cardiovascular System)
             Endocardial Tube Cells Endocardium
     
     Ovary (Reproductive System)
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
     
     Umbilical Cord (Extraembryonic Tissues)
             Wharton's jelly-derived stem cells
    SDPR Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SDPR Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.26530

    UniProtKB/Swiss-Prot: SDPR_HUMAN, O95810
    Tissue specificity: Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver,
    pancreas, placenta, and skeletal muscle

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SDPR gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sdpr1 , 5 serum deprivation response1, 5 82.93(n)1
    83.97(a)1
      1 (26.13 cM)5
    203241  NM_138741.11  NP_620080.11 
     512891265 
    chicken
    (Gallus gallus)
    Aves SDPR1 serum deprivation response 66.13(n)
    61.66(a)
      424047  XM_421903.3  XP_421903.2 
    African clawed frog
    (Xenopus laevis)
    Amphibia CD328102.12   -- 76.29(n)    CD328102.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CK127005.12   -- 75.54(n)    CK127005.1 


    ENSEMBL Gene Tree for SDPR (if available)
    TreeFam Gene Tree for SDPR (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SDPR gene
    PRKCDBP2  PTRF2  MURC2  
    2 SIMAP similar genes for SDPR using alignment to 1 protein entry:     SDPR_HUMAN:
    PRKCDBP    PTRF

    SDPR for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SDPR (see all 288)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1896730151,2
    --192698563(+) CAGCTA/GGTTTC 1 -- ds50010--------
    rs1816161051,2
    --192698582(+) CAGCTA/GCAAGA 1 -- ds50010--------
    rs799132921,2
    C,F--192698793(+) TATCAA/GACTCA 1 -- ds50011Minor allele frequency- G:0.06NA 120
    rs1861368121,2
    --192698798(+) AACTCA/GTCAAG 1 -- ds50010--------
    rs1393499831,2
    C--192699174(+) ATCCTA/GTCCCT 1 -- ut310--------
    rs1496187411,2
    --192699443(+) AGTTAA/GGAAAT 1 -- ut310--------
    rs1907914331,2
    --192699473(+) AATATA/GTAAAT 1 -- ut310--------
    rs748948841,2
    --192699502(+) AAATTC/GCCATT 1 -- ut310--------
    rs2010726551,2
    C--192699637(+) TAGTAG/TGAGCT 1 -- ut310--------
    rs2019414741,2
    C--192699639(-) TTAGCC/TCATAC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SDPR (192699028 - 192712006 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SDPR:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv834494CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SDPR
    DNA2.0 Custom Variant and Variant Library Synthesis for SDPR

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606728    OMIM disorders: --

    7 diseases for SDPR:    
    About MalaCards
    spondylolisthesis    quadriplegia    cerebral palsy    cerebritis
    thyroiditis    breast cancer    endotheliitis


    SDPR for disorders           About GeneDecksing


    Export disorders for SDPR gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SDPR gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with SDPR)
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    1. The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein. (PubMed id 10191091)1, 2, 3, 9 Gustincich S.... Schneider C. (Genomics 1999)
    2. Purification and characterization of a major phosphatidylserine- binding phosphoprotein from human platelets. (PubMed id 2390065)1, 2, 9 Burgener R.... Baggiolini M. (Biochem. J. 1990)
    3. MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. (PubMed id 18332105)1, 2 Ogata T.... Oh H. (Mol. Cell. Biol. 2008)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Serum deprivation response gene is induced by serum starvation but not by contact inhibition. (PubMed id 8241023)1, 3 Gustincich S. and Schneider C. (amp 1993)
    7. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. Down-regulation of the cavin family proteins in breast cancer. (PubMed id 21913217)1 Bai L....Cong Y.S. (J. Cell. Biochem. 2012)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8436 HGNC: 10690 AceView: SDPR Ensembl:ENSG00000168497 euGenes: HUgn8436
    ECgene: SDPR H-InvDB: SDPR

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SDPR Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SDPR gene:
    Search GeneIP for patents involving SDPR

    GeneCards and IP:
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