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Aliases for SDIM1 Gene

Aliases for SDIM1 Gene

  • Stress Responsive DNAJB4 Interacting Membrane Protein 1 2 3

External Ids for SDIM1 Gene

Summaries for SDIM1 Gene

GeneCards Summary for SDIM1 Gene

SDIM1 (Stress Responsive DNAJB4 Interacting Membrane Protein 1) is a Protein Coding gene. GO annotations related to this gene include protein homodimerization activity.

UniProtKB/Swiss-Prot for SDIM1 Gene

  • Promotes neuronal cells survival to stress conditions.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SDIM1 Gene

Genomics for SDIM1 Gene

Genomic Location for SDIM1 Gene

Orientation:
Unknown strand

Genomic View for SDIM1 Gene

Cytogenetic band:

RefSeq DNA sequence for SDIM1 Gene

No data available for Regulatory Elements for SDIM1 Gene

Proteins for SDIM1 Gene

  • Protein details for SDIM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZPB5-SDIM1_HUMAN
    Recommended name:
    Stress-responsive DNAJB4-interacting membrane protein 1
    Protein Accession:
    Q6ZPB5
    Secondary Accessions:

    Protein attributes for SDIM1 Gene

    Size:
    146 amino acids
    Molecular mass:
    16112 Da
    Quaternary structure:
    • Homodimer. Interacts with DNAJB4.

neXtProt entry for SDIM1 Gene

Proteomics data for SDIM1 Gene at MOPED

Post-translational modifications for SDIM1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SDIM1 Gene

Domains for SDIM1 Gene

Protein Domains for SDIM1 Gene

ProtoNet:
genes like me logo Genes that share domains with SDIM1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SDIM1 Gene

Function for SDIM1 Gene

Molecular function for SDIM1 Gene

UniProtKB/Swiss-Prot Function: Promotes neuronal cells survival to stress conditions.
UniProtKB/Swiss-Prot Induction: Down-regulated in NT2 neurons subjected to stress conditions which triggers neuronal apoptosis such as oxygen and glucose deprivation, followed by up-regulation in surviving cells.

Gene Ontology (GO) - Molecular Function for SDIM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21255413
GO:0042803 protein homodimerization activity IDA 21255413
genes like me logo Genes that share ontologies with SDIM1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SDIM1 Gene

Localization for SDIM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SDIM1 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SDIM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SDIM1: view

Pathways for SDIM1 Gene

SuperPathways for SDIM1 Gene

No Data Available

Interacting Proteins for SDIM1 Gene

Gene Ontology (GO) - Biological Process for SDIM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0033554 cellular response to stress IEP 21255413
GO:0051402 neuron apoptotic process IDA 21255413
GO:0060548 negative regulation of cell death IDA 21255413
genes like me logo Genes that share ontologies with SDIM1: view

No data available for Pathways by source for SDIM1 Gene

Transcripts for SDIM1 Gene

mRNA/cDNA for SDIM1 Gene

(4) Additional mRNA sequences :

Unigene Clusters for SDIM1 Gene

Stress responsive DNAJB4 interacting membrane protein 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SDIM1 Gene

No ASD Table

Relevant External Links for SDIM1 Gene

ECgene alternative splicing isoforms for
SDIM1

Expression for SDIM1 Gene

mRNA expression in normal human tissues for SDIM1 Gene

mRNA differential expression in normal tissues according to GTEx for SDIM1 Gene

This gene is overexpressed in Ovary (8.6), Brain - Cerebellum (7.6), Pituitary (5.8), and Brain - Cerebellar Hemisphere (5.6).

SOURCE GeneReport for Unigene cluster for SDIM1 Gene Hs.722069

mRNA Expression by UniProt/SwissProt for SDIM1 Gene

Q6ZPB5-SDIM1_HUMAN
Tissue specificity: Expressed in brain with higher detection in neurons than astrocytes. Decreased expression in Alzheimer brains. Detected at protein level in brain and cervix.
genes like me logo Genes that share expressions with SDIM1: view

Orthologs for SDIM1 Gene

No data available for Orthologs and Evolution for SDIM1 Gene

Paralogs for SDIM1 Gene

No data available for Paralogs for SDIM1 Gene

Variants for SDIM1 Gene

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for SDIM1 Gene

Disorders for SDIM1 Gene

No disorders were found for SDIM1 Gene.

No data available for UniProtKB/Swiss-Prot for SDIM1 Gene

Publications for SDIM1 Gene

  1. A novel neuron-enriched protein SDIM1 is down regulated in Alzheimer's brains and attenuates cell death induced by DNAJB4 over- expression in neuro-progenitor cells. (PMID: 21255413) Lei J.X. … Liu Q.Y. (Mol. Neurodegener. 2011) 2 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for SDIM1 Gene

Sources for SDIM1 Gene

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