Aliases for SDHAF3 Gene
External Ids for SDHAF3 Gene
Previous HGNC Symbols for SDHAF3 Gene
GeneCards Summary for SDHAF3 Gene
SDHAF3 (Succinate Dehydrogenase Complex Assembly Factor 3) is a Protein Coding gene.
UniProtKB/Swiss-Prot for SDHAF3 Gene
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.