Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SDF2L1 Gene

Aliases for SDF2L1 Gene

  • Stromal Cell-Derived Factor 2-Like 1 2 3
  • PWP1-Interacting Protein 8 2 3 4
  • Dihydropyrimidinase-Like 2 2 3
  • SDF2-Like Protein 1 3 4
  • Stromal Cell-Derived Factor 2-Like Protein 1 3
  • OTTHUMT00000075032 3
  • SDF2-Like 1 3

External Ids for SDF2L1 Gene

Previous GeneCards Identifiers for SDF2L1 Gene

  • GC22P018695
  • GC22P020320
  • GC22P020321
  • GC22P021996
  • GC22P004954

Summaries for SDF2L1 Gene

GeneCards Summary for SDF2L1 Gene

SDF2L1 (Stromal Cell-Derived Factor 2-Like 1) is a Protein Coding gene. An important paralog of this gene is SDF2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SDF2L1 Gene

Genomics for SDF2L1 Gene

Regulatory Elements for SDF2L1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SDF2L1 Gene

Start:
21,642,253 bp from pter
End:
21,644,299 bp from pter
Size:
2,047 bases
Orientation:
Plus strand

Genomic View for SDF2L1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SDF2L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SDF2L1 Gene

Proteins for SDF2L1 Gene

  • Protein details for SDF2L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HCN8-SDF2L_HUMAN
    Recommended name:
    Stromal cell-derived factor 2-like protein 1
    Protein Accession:
    Q9HCN8
    Secondary Accessions:
    • A2RUD3
    • Q9BRI5

    Protein attributes for SDF2L1 Gene

    Size:
    221 amino acids
    Molecular mass:
    23598 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SDF2L1 Gene

Proteomics data for SDF2L1 Gene at MOPED

Post-translational modifications for SDF2L1 Gene

  • Glycosylation at Ser211
  • Modification sites at PhosphoSitePlus

Other Protein References for SDF2L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SDF2L1 Gene

Domains for SDF2L1 Gene

Protein Domains for SDF2L1 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SDF2L1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9HCN8

UniProtKB/Swiss-Prot:

SDF2L_HUMAN :
  • Q9HCN8
Domain:
  • Contains 3 MIR domains.
genes like me logo Genes that share domains with SDF2L1: view

No data available for Gene Families for SDF2L1 Gene

Function for SDF2L1 Gene

Molecular function for SDF2L1 Gene

GENATLAS Biochemistry: stromal cell-derived factor 2-like 1

Gene Ontology (GO) - Molecular Function for SDF2L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051087 chaperone binding IEA --
GO:0051117 ATPase binding IEA --
GO:0051787 misfolded protein binding IEA --
genes like me logo Genes that share ontologies with SDF2L1: view
genes like me logo Genes that share phenotypes with SDF2L1: view

Animal Model Products

CRISPR Products

miRNA for SDF2L1 Gene

miRTarBase miRNAs that target SDF2L1

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SDF2L1 Gene

Localization for SDF2L1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SDF2L1 Gene

Endoplasmic reticulum lumen.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SDF2L1 Gene COMPARTMENTS Subcellular localization image for SDF2L1 gene
Compartment Confidence
endoplasmic reticulum 3
extracellular 3

Gene Ontology (GO) - Cellular Components for SDF2L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum --
GO:0005788 endoplasmic reticulum lumen IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with SDF2L1: view

Pathways for SDF2L1 Gene

SuperPathways for SDF2L1 Gene

No Data Available

Interacting Proteins for SDF2L1 Gene

Gene Ontology (GO) - Biological Process for SDF2L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0034976 response to endoplasmic reticulum stress IEA --
GO:0042981 regulation of apoptotic process IEA --
GO:0071218 cellular response to misfolded protein --
GO:0071712 ER-associated misfolded protein catabolic process IEA --
genes like me logo Genes that share ontologies with SDF2L1: view

No data available for Pathways by source for SDF2L1 Gene

Transcripts for SDF2L1 Gene

mRNA/cDNA for SDF2L1 Gene

Unigene Clusters for SDF2L1 Gene

Stromal cell-derived factor 2-like 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SDF2L1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SDF2L1 Gene

No ASD Table

Relevant External Links for SDF2L1 Gene

GeneLoc Exon Structure for
SDF2L1
ECgene alternative splicing isoforms for
SDF2L1

Expression for SDF2L1 Gene

mRNA expression in normal human tissues for SDF2L1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SDF2L1 Gene

This gene is overexpressed in Liver (5.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SDF2L1 Gene

SOURCE GeneReport for Unigene cluster for SDF2L1 Gene Hs.303116

mRNA Expression by UniProt/SwissProt for SDF2L1 Gene

Q9HCN8-SDF2L_HUMAN
Tissue specificity: Ubiquitously expressed with high expression in testis, moderate expression in the pancreas, spleen, prostate, small intestine and colon. Very low expression is seen in brain and skeletal muscle.
genes like me logo Genes that share expressions with SDF2L1: view

In Situ Assay Products

Orthologs for SDF2L1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SDF2L1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SDF2L1 35
  • 99.25 (n)
  • 99.1 (a)
SDF2L1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SDF2L1 35
  • 87.93 (n)
  • 88.69 (a)
SDF2L1 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SDF2L1 35
  • 90.65 (n)
  • 95.93 (a)
SDF2L1 36
  • 65 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Sdf2l1 35
  • 85.37 (n)
  • 89.14 (a)
Sdf2l1 16
Sdf2l1 36
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-130b 36
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SDF2L1 36
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Sdf2l1 35
  • 86.77 (n)
  • 93.81 (a)
chicken
(Gallus gallus)
Aves SDF2L1 35
  • 72.25 (n)
  • 82.7 (a)
SDF2L1 36
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SDF2L1 36
  • 71 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.5458 35
tropical clawed frog
(Silurana tropicalis)
Amphibia sdf2l1 35
  • 65.28 (n)
  • 73.06 (a)
zebrafish
(Danio rerio)
Actinopterygii sdf2l1 35
  • 65.28 (n)
  • 70.98 (a)
sdf2l1 36
  • 64 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG11999 36
  • 45 (a)
OneToMany
CG11999 37
  • 51 (a)
worm
(Caenorhabditis elegans)
Secernentea R12E2.13 36
  • 43 (a)
OneToMany
R12E2.13 37
  • 50 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11079 36
  • 46 (a)
OneToMany
Species with no ortholog for SDF2L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SDF2L1 Gene

ENSEMBL:
Gene Tree for SDF2L1 (if available)
TreeFam:
Gene Tree for SDF2L1 (if available)

Paralogs for SDF2L1 Gene

Paralogs for SDF2L1 Gene

Selected SIMAP similar genes for SDF2L1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SDF2L1: view

Variants for SDF2L1 Gene

Structural Variations from Database of Genomic Variants (DGV) for SDF2L1 Gene

Variant ID Type Subtype PubMed ID
nsv7350 OTHER Inversion 18451855
nsv914458 CNV Loss 21882294
dgv4881n71 CNV Loss 21882294
nsv516806 CNV Loss 19592680
dgv4882n71 CNV Loss 21882294
nsv914469 CNV Loss 21882294

Relevant External Links for SDF2L1 Gene

HapMap Linkage Disequilibrium report
SDF2L1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for SDF2L1 Gene

Disorders for SDF2L1 Gene

Relevant External Links for SDF2L1

Genetic Association Database (GAD)
SDF2L1
genes like me logo Genes that share disorders with SDF2L1: view

No data available for UniProtKB/Swiss-Prot for SDF2L1 Gene

Publications for SDF2L1 Gene

  1. Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family. (PMID: 11162531) Fukuda S. … Kamiya K. (Biochem. Biophys. Res. Commun. 2001) 2 3 4 23
  2. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 2 3
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  4. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for SDF2L1 Gene

Sources for SDF2L1 Gene

Back to Top

Content