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Aliases & Descriptions for SDCCAG1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| FLJ10051 1, 2 | | NY-CO-1 1, 2 |
| | | Descriptions |
|---|
| Antigen NY-CO-1 3 | | serologically defined colon cancer antigen 1 2 |
|
| | Search outside databases for aliases for SDCCAG1 genePrevious GC identifers: GC14M047572 GC14M044046 GC14M048240 |
Summaries for SDCCAG1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Location for SDCCAG1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the SDCCAG1 gene 
Entrez Gene cytogenetic band: 14q22 Ensembl cytogenetic band: 14q22.1 HGNC cytogenetic band: 14q22SDCCAG1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M049320:
(about GC identifiers)
Start:
|
49,320,282 bp from pter |
End:
|
49,389,289 bp from pter |
Size:
|
69,008 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000014.7 NT_026437.11
| Proteins for SDCCAG1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: SDCG1_HUMAN, O60524 (See
protein sequence)Recommended Name: Serologically defined colon cancer antigen 1 Size: 1076 amino acids; 122970 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=AAC18036.1; Type=Frameshift; Positions=1065; Sequence=AAH56687.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;
Secondary accessions: Q8WW70 Q9NWG1Alternative splicing: 2 isoforms: O60524-1 O60524-2 Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_004704.2
ENSEMBL proteins: ENSP00000371570 ENSP00000298310
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for SDCCAG1: Assays for SDCCAG1: | Protein
Domains/ Families for SDCCAG1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry O60524
ProtoNet protein and cluster: O60524 1 Blocks protein family: IPB008532 Protein of unknown function DUF814
UniProtKB/Swiss-Prot: SDCG1_HUMAN, O60524Similarity: Belongs to the SDCCAG1 family | Gene Function for SDCCAG1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004713
Applied Biosystems Silencer® siRNAs for SDCCAG1
Sigma-Aldrich siRNA for SDCCAG1  Sigma-Aldrich shRNA for SDCCAG1  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004713                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_004713                                  untagged cDNA clone in CMV expression vector: NM_004713 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_004713
Genatlas biochemistry entry for SDCCAG1:serologically defined colon cancer NY-CO-1 | Pathways & Interactions for SDCCAG1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
3 Interacting proteins for SDCCAG1 (ENSP000002983103) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds for SDCCAG1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for SDCCAG1
|
Transcripts for SDCCAG1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004713
Sigma-Aldrich siRNA for SDCCAG1  Sigma-Aldrich shRNA for SDCCAG1  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_004713 REFSEQ mRNAs for SDCCAG1 gene: NM_004713.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_004713               OriGene GFP tagged cDNA clone in CMV expression vector: NM_004713                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_004713                                  untagged cDNA clone in CMV expression vector: NM_004713  Additional cDNA sequence: AF039687.1 AK000913.1 AK093783.1 AK293236.1 AK295010.1 AK304695.1 AK308537.1 AK314281.1 BC006001.1 BC020794.2 BC056687.1 BC064364.1 BC107764.1 BX640804.1 BX640807.1 BX648598.1 BX648753.1 24/27 DOTS entries (see all 27
): DT.314388 DT.100679213 DT.207458 DT.97845610 DT.100737565 DT.101984317 DT.70103737 DT.95338023 DT.100737564 DT.95266837 DT.40130729 DT.86850342 DT.95257653 DT.95269900 DT.100754441 DT.120747983 DT.120748053 DT.120748055 DT.40113659 DT.40118666 DT.40228562 DT.100652426 DT.422407 DT.91817523 24/208 AceView cDNA sequences (see all 208
):BC031007 F28854 AI147994 BE502352 BF984340 BM785476 BQ632296 BQ426116 BM455267 AW237403 AK000913 AW467242 BM477286 AJ457797 AA159181 BG287032 CR597660 AA669916 AA553574 AK093783 NM_004713 CA392683 AX748304 AA626602
highest scoring ESTs for SDCCAG1:AA159181 AL121422 BG942209 AA159259 AK000913 AU117386 BC006001 BC056687 BE255217 BF219060 Unigene Cluster for SDCCAG1: Serologically defined colon cancer antigen 1 Hs.655964 [show with all ESTs]Unigene Representative Sequence: NM_004713
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SDCCAG1 (see all 9
)
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | |
| SP1: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 22 | ^ | 23 | ^ | 24a | · | 24b | ^ | 25 | ^ | 26 | ^ | 27a | · | 27b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | - |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for SDCCAG1
2 Ensembl transcripts including schematic representations: ENST00000382135
ENST00000298310
|
Expression for SDCCAG1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| SDCCAG1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for SDCCAG1
1 / 2 / 3 7 probe-sets matching SDCCAG1 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.655964
Expression variation in blood from EXPOLDB for SDCCAG1 |
Orthologs for SDCCAG1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for SDCCAG1 gene from 5/21 species (see all 21
)
About this table Species with no ortholog for SDCCAG1
ENSEMBL Gene Tree for SDCCAG1 | Paralogs for SDCCAG1(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for SDCCAG1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for SDCCAG1 (up to first 250kb)
|
Disorders & Mutations for SDCCAG1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 608378
|
Medical News for SDCCAG1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for SDCCAG1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10 PubMed articles for SDCCAG1 gene:- Characterization of human colon cancer antigens recognized by autologous antibodies. (PubMed id 9610721)2, 3, 4 Scanlan M.J....Old L.J. (1998)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)3, 4 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)3, 4 Ota T....Sugano S. (2004)
- Assignment of the serologically defined colon cancer antigen 1 gene (SDCCAG1) to human chromosome band 14q22 by in situ hybridization. (PubMed id 10575219)2, 3 Carbonnelle D....Roussakis C. (1999)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)4 Dephoure N.... Gygi S.P. (2008)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)3 Barbe L....Andersson-Svahn H. (2008)
- The full-ORF clone resource of the German cDNA Consortium. (PubMed id 17974005)4 Bechtel S....Schupp I. (2007)
- Drosophila caliban, a nuclear export mediator, can function as a tumor suppressor in human lung cancer cells. (PubMed id 16103875)3 Bi X....Mortin M.A. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
|
Search for SDCCAG1
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SDCCAG1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing SDCCAG1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SDCCAG1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for SDCCAG1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for SDCCAG1:

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GeneCards Homepage - Last full update: 1 Jul 2009
Incremental update: 13 Oct 2009
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