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Aliases for SDAD1 Gene

Aliases for SDAD1 Gene

  • SDA1 Domain Containing 1 2 3
  • SDA1 Domain-Containing Protein 1 4
  • Nucleolar Protein 130 4
  • NUC130 4
  • HSDA 4

External Ids for SDAD1 Gene

Summaries for SDAD1 Gene

GeneCards Summary for SDAD1 Gene

SDAD1 (SDA1 Domain Containing 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for SDAD1 Gene

  • Required for 60S pre-ribosomal subunits export to the cytoplasm.

Gene Wiki entry for SDAD1 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SDAD1 Gene

Genomics for SDAD1 Gene

Genomic Location for SDAD1 Gene

75,940,950 bp from pter
75,990,962 bp from pter
50,013 bases
Minus strand

Genomic View for SDAD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SDAD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SDAD1 Gene

Regulatory Elements for SDAD1 Gene

Proteins for SDAD1 Gene

  • Protein details for SDAD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein SDA1 homolog
    Protein Accession:
    Secondary Accessions:
    • Q32Q11
    • Q68D52
    • Q7Z5U4
    • Q9H831
    • Q9H9P6

    Protein attributes for SDAD1 Gene

    687 amino acids
    Molecular mass:
    79871 Da
    Quaternary structure:
    No Data Available
    • DAZL and PUM2 bind its 3-UTR mRNA, suggesting that these proteins may regulate its translation
    • Sequence=AAI07896.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAA91648.1; Type=Frameshift; Positions=53; Evidence={ECO:0000305}; Sequence=BAB14177.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB14790.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for SDAD1 Gene


neXtProt entry for SDAD1 Gene

Proteomics data for SDAD1 Gene at MOPED

Post-translational modifications for SDAD1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys21

Other Protein References for SDAD1 Gene

No data available for DME Specific Peptides for SDAD1 Gene

Domains for SDAD1 Gene

Protein Domains for SDAD1 Gene

Suggested Antigen Peptide Sequences for SDAD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SDA1 family.:
    • Q9NVU7
genes like me logo Genes that share domains with SDAD1: view

No data available for Gene Families for SDAD1 Gene

Function for SDAD1 Gene

Molecular function for SDAD1 Gene

UniProtKB/Swiss-Prot Function: Required for 60S pre-ribosomal subunits export to the cytoplasm.

Gene Ontology (GO) - Molecular Function for SDAD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005488 binding --
genes like me logo Genes that share ontologies with SDAD1: view

Phenotypes for SDAD1 Gene

genes like me logo Genes that share phenotypes with SDAD1: view

miRNA for SDAD1 Gene

miRTarBase miRNAs that target SDAD1

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SDAD1 Gene

Localization for SDAD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SDAD1 Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for SDAD1 Gene COMPARTMENTS Subcellular localization image for SDAD1 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for SDAD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with SDAD1: view

Pathways for SDAD1 Gene

SuperPathways for SDAD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SDAD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000055 ribosomal large subunit export from nucleus IEA --
GO:0015031 protein transport IEA --
GO:0030036 actin cytoskeleton organization IEA --
GO:0042273 ribosomal large subunit biogenesis ISS --
genes like me logo Genes that share ontologies with SDAD1: view

No data available for Pathways by source for SDAD1 Gene

Transcripts for SDAD1 Gene

Unigene Clusters for SDAD1 Gene

SDA1 domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SDAD1 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b
SP1: -

Relevant External Links for SDAD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SDAD1 Gene

mRNA expression in normal human tissues for SDAD1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SDAD1 Gene

SOURCE GeneReport for Unigene cluster for SDAD1 Gene Hs.632604

mRNA Expression by UniProt/SwissProt for SDAD1 Gene

Tissue specificity: Highly expressed in testis, kidney, spleen, brain and fetal tissues. Also expressed at lower level in heart, lung, liver, small intestine, ovary, uterus, mammary gland and placenta.
genes like me logo Genes that share expressions with SDAD1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for SDAD1 Gene

Orthologs for SDAD1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SDAD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SDAD1 35
  • 99.71 (n)
  • 100 (a)
SDAD1 36
  • 100 (a)
(Bos Taurus)
Mammalia SDAD1 35
  • 91.12 (n)
  • 94.32 (a)
SDAD1 36
  • 95 (a)
(Canis familiaris)
Mammalia SDAD1 35
  • 89.59 (n)
  • 91.35 (a)
SDAD1 36
  • 89 (a)
(Mus musculus)
Mammalia Sdad1 35
  • 87.82 (n)
  • 94.03 (a)
Sdad1 16
Sdad1 36
  • 94 (a)
(Monodelphis domestica)
Mammalia SDAD1 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia SDAD1 36
  • 79 (a)
(Rattus norvegicus)
Mammalia Sdad1 35
  • 86.78 (n)
  • 94.02 (a)
(Gallus gallus)
Aves SDAD1 35
  • 77.7 (n)
  • 83.67 (a)
SDAD1 36
  • 83 (a)
(Anolis carolinensis)
Reptilia SDAD1 36
  • 83 (a)
African clawed frog
(Xenopus laevis)
Amphibia LOC398506 35
tropical clawed frog
(Silurana tropicalis)
Amphibia sdad1 35
  • 74.31 (n)
  • 81.9 (a)
Str.17243 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.1827 35
(Danio rerio)
Actinopterygii flj10498 35
sdad1 35
  • 73.24 (n)
  • 78.24 (a)
sdad1 36
  • 78 (a)
fruit fly
(Drosophila melanogaster)
Insecta Mys45A 35
  • 57.21 (n)
  • 53.13 (a)
Mys45A 36
  • 50 (a)
(Caenorhabditis elegans)
Secernentea pro-3 35
  • 51.27 (n)
  • 41.85 (a)
pro-3 36
  • 34 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AEL212W 35
  • 46.48 (n)
  • 38.69 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SDA1 36
  • 34 (a)
SDA1 38
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4149 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6735 36
  • 55 (a)
Species with no ortholog for SDAD1:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SDAD1 Gene

Gene Tree for SDAD1 (if available)
Gene Tree for SDAD1 (if available)

Paralogs for SDAD1 Gene

genes like me logo Genes that share paralogs with SDAD1: view

No data available for Paralogs for SDAD1 Gene

Variants for SDAD1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for SDAD1 Gene

Variations in SDAD1 may be a cause of susceptibility to seasonal allergic rhinitis (SAR). SAR is a common allergic disorder characterized by episodes of sneezing, rhinorrhea, and swelling of the nasal mucosa

Sequence variations from dbSNP and Humsavar for SDAD1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs2273 -- 75,968,235(+) TCCTA(C/T)ACTGG intron-variant
rs7154 -- 75,950,030(-) GAATA(C/T)ATTTA utr-variant-3-prime
rs15480 -- 75,971,407(+) ACTTT(G/T)CTTCC reference, missense
rs15481 - 75,971,398(-) GTTCC(A/C)AAAAC reference, missense
rs533820 -- 75,950,247(+) AGTAA(A/G)AACCT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SDAD1 Gene

Variant ID Type Subtype PubMed ID
nsv7363 OTHER Inversion 18451855

Relevant External Links for SDAD1 Gene

HapMap Linkage Disequilibrium report

Disorders for SDAD1 Gene

Relevant External Links for SDAD1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with SDAD1: view

No data available for UniProtKB/Swiss-Prot for SDAD1 Gene

Publications for SDAD1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  2. Joint influence of small-effect genetic variants on human longevity. (PMID: 20834067) Yashin A.I. … Ukraintseva S.V. (Aging (Albany NY) 2010) 3 48
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Expression and localization studies of hSDA, the human ortholog of the yeast SDA1 gene. (PMID: 14976432) Babbio F. … Privitera E. (Cell Cycle 2004) 3 4
  5. Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind. (PMID: 15607425) Fox M. … Reijo Pera R.A. (Genomics 2005) 3 4

Products for SDAD1 Gene

Sources for SDAD1 Gene

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