Aliases for SCYL2 Gene
Aliases for SCYL2 Gene
External Ids for SCYL2 Gene
- HGNC: 19286
- Entrez Gene: 55681
- Ensembl: ENSG00000136021
- OMIM: 616365
- UniProtKB: Q6P3W7
Previous GeneCards Identifiers for SCYL2 Gene
- GC12P099164
- GC12P100661
- GC12P097722
Summaries for SCYL2 Gene
-
The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for SCYL2 Gene
SCYL2 (SCY1 Like Pseudokinase 2) is a Protein Coding gene. Diseases associated with SCYL2 include Cataract 8, Multiple Types. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and binding.
UniProtKB/Swiss-Prot for SCYL2 Gene
-
Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. According to PubMed:16914521, has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SCYL2 Gene
Genomics for SCYL2 Gene
Regulatory Elements for SCYL2 Gene
Enhancers for SCYL2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH12G100185 | 0.6 | Ensembl | 10.8 | -81.5 | -81537 | 0.8 | FOXA2 ZNF644 RARA SMARCA4 POLR2A SMAD4 HOMEZ SPI1 | UHRF1BP1L SCYL2 DEPDC4 MIR1827 PIR35895 |
| GH12G100266 | 1.1 | ENCODE | 5.8 | +0.8 | 838 | 3.6 | HDGF PKNOX1 ARNT ZFP64 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 | ACTR6 SCYL2 RN7SL176P DEPDC4 GC12M100341 |
| GH12G100279 | 0.5 | ENCODE | 4.6 | +13.0 | 13047 | 0.7 | PBX2 HMBOX1 HNF4A | SLC17A8 ACTR6 SCYL2 DEPDC4 GC12M100341 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around SCYL2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for SCYL2 Gene
- Chromosome:
- 12
- Start:
- 100,267,137 bp from pter
- End:
- 100,341,724 bp from pter
- Size:
- 74,588 bases
- Orientation:
- Plus strand
Genomic View for SCYL2 Gene
Genes around SCYL2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q23.1 by Ensembl
- 12q23.1 by Entrez Gene
- 12q23.1 by HGNC
SCYL2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SCYL2 Gene
Proteins for SCYL2 Gene
-
Protein details for SCYL2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6P3W7-SCYL2_HUMAN
- Recommended name:
- SCY1-like protein 2
- Protein Accession:
- Q6P3W7
- A8KAB5
- Q96EF4
- Q96ST4
- Q9H7V5
- Q9NVH3
- Q9P2I7
Protein attributes for SCYL2 Gene
- Size:
- 929 amino acids
- Molecular mass:
- 103709 Da
- Quaternary structure:
-
- Interacts with clathrin and AP2B1; the interaction mediates the association with the AP-2 complex.
- SequenceCaution:
-
- Sequence=BAA91778.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB14869.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB55194.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for SCYL2 Gene
Post-translational modifications for SCYL2 Gene
- According to PubMed:15809293, autophosphorylated in presence of poly-L-lysine.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for SCYL2 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for SCYL2
- Novus Biologicals Antibodies for SCYL2
- Invitrogen Antibodies for SCYL2
- antibodies-online Antibodies for SCYL2: See all 44
- Search GeneTex for Antibodies for SCYL2
Protein Products
-
OriGene Purified Proteins for SCYL2
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- antibodies-online Proteins for SCYL2: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for SCYL2
Assay Products
- antibodies-online Kits for SCYL2: See all 1
No data available for DME Specific Peptides for SCYL2 Gene
Domains & Families for SCYL2 Gene
Gene Families for SCYL2 Gene
- HGNC:
- IUPHAR :
Protein Domains for SCYL2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for SCYL2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6P3W7- Family:
-
- Belongs to the protein kinase superfamily.
Function for SCYL2 Gene
Molecular function for SCYL2 Gene
- UniProtKB/Swiss-Prot Function:
- Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. According to PubMed:16914521, has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004672 | protein kinase activity | IEA | -- |
| GO:0005102 | receptor binding | IPI | 19643732 |
| GO:0005515 | protein binding | IPI | 19643732 |
| GO:0005524 | ATP binding | IEA | -- |
Phenotypes for SCYL2 Gene
- MGI mutant phenotypes for SCYL2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for SCYL2:
-
- shRNA abundance <= 50%
- Mildly decreased CFP-tsO45G cell surface transport
- Lamellipodia cells
- Increased transferrin (TF) endocytosis
- Decreased viability
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased homologous recombination repair frequency
- Decreased human cytomegalovirus (HCMV) strain AD169 replication
- Decreased centriole number
Animal Models for SCYL2 Gene
- MGI Knock Outs for SCYL2:
-
- Scyl2 tm1.2Spel
Animal Model Products
-
Taconic Biosciences Mouse Models for SCYL2
- Cyagen custom Knockout/knockin (KOKI) mouse models for SCYL2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SCYL2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SCYL2 gene
- Search ViGene Biosciences for SCYL2
CRISPR Products
-
OriGene CRISPR knockouts for SCYL2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SCYL2
- GenScript: Design CRISPR guide RNA sequences for SCYL2
miRNA for SCYL2 Gene
- miRTarBase miRNAs that target SCYL2
miRNA Products
- Search ViGene Biosciences for SCYL2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for SCYL2
- Browse OriGene Inhibitory RNA Products For SCYL2
-
ViGene Biosciences ready-to-package AAV shRNAs for SCYL2 gene
Clone Products
-
OriGene ORF clones in human for SCYL2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for SCYL2
- VectorBuilder custom plasmid, inducible vectors for SCYL2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SCYL2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for SCYL2
-
ViGene Biosciences adenoviral particle packaged cDNA for SCYL2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SCYL2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SCYL2 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SCYL2 Gene
Localization for SCYL2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SCYL2 Gene
- Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Note=According to PubMed:15809293, plasma membrane-associated in clathrin-coated vesicles. According to PubMed:16914521, colocalizes to the trans-Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes.
| Compartment | Confidence |
|---|---|
| golgi apparatus | 5 |
| endosome | 5 |
| cytosol | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005768 | endosome | IEA | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0010008 | endosome membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for SCYL2 Gene
No Data Available
Interacting Proteins for SCYL2 Gene
Selected Interacting proteins:
Q6P3W7-SCYL2_HUMAN
ENSP00000354061
for SCYL2 Gene via
IID
UniProtKB
STRING
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002092 | positive regulation of receptor internalization | IDA | 19643732 |
| GO:0006468 | protein phosphorylation | IEA | -- |
| GO:0008333 | endosome to lysosome transport | IDA | 19643732 |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway | IDA | 19643732 |
| GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway | IDA | 19643732 |
No data available for Pathways by source and SIGNOR curated interactions for SCYL2 Gene
Transcripts for SCYL2 Gene
mRNA/cDNA for SCYL2 Gene
- (8) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (170) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SCYL2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for SCYL2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SCYL2
- GenScript: Design CRISPR guide RNA sequences for SCYL2
miRNA Products
- Search ViGene Biosciences for SCYL2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for SCYL2
- Browse OriGene Inhibitory RNA Products For SCYL2
-
ViGene Biosciences ready-to-package AAV shRNAs for SCYL2 gene
Clone Products
-
OriGene ORF clones in human for SCYL2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for SCYL2
- VectorBuilder custom plasmid, inducible vectors for SCYL2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SCYL2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for SCYL2 Gene
This gene is overexpressed in Platelet (6.7) and Peripheral blood mononuclear cells (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SCYL2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SCYL2 Gene:
SCYL2SOURCE GeneReport for Unigene cluster for SCYL2 Gene:
Hs.506481Evidence on tissue expression from TISSUES for SCYL2 Gene
- Nervous system(4.5)
Primer Products
-
OriGene qPCR primer pairs and template standards for SCYL2
-
OriGene qPCR primer pairs for SCYL2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SCYL2 Gene
Orthologs for SCYL2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SCYL2 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SCYL2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | SCYL2 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | SCYL2 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SCYL2 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Scyl2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Scyl2 34 16 35 |
|
||
| chicken (Gallus gallus) |
Aves | SCYL2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | SCYL2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | scyl2 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | SCYL2 35 |
|
OneToOne | |
| si:ch211-244b2.1 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG1951 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002142 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | ZC581.9 35 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SCY1 35 37 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne |
- Species where no ortholog for SCYL2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for SCYL2 Gene
Pseudogenes.org Pseudogenes for SCYL2 Gene
No data available for Paralogs for SCYL2 Gene
Variants for SCYL2 Gene
| SNP ID | Clin | Chr 12 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_041370 | A lung adenocarcinoma sample | ||||
| rs1000002371 | -- | 100,332,102(+) | AAACC(A/G)GGCAC | intron-variant | |
| rs1000015151 | -- | 100,297,739(+) | TTGAA(A/C)AAGGT | intron-variant | |
| rs1000070133 | -- | 100,266,201(+) | TTCTC(C/T)AACTA | intron-variant, upstream-variant-2KB | |
| rs1000137175 | -- | 100,304,068(+) | AAAAC(C/T)ACCTA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2364259 | CNV | deletion | 18987734 |
| esv2518688 | CNV | deletion | 19546169 |
| esv2672785 | CNV | deletion | 23128226 |
| esv2746277 | CNV | deletion | 23290073 |
| esv3549674 | CNV | deletion | 23714750 |
| esv3580426 | CNV | loss | 25503493 |
| nsv1070124 | CNV | deletion | 25765185 |
| nsv559964 | CNV | gain | 21841781 |
| nsv958649 | CNV | deletion | 24416366 |
| nsv977143 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
7.58% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.91;
67.72% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for SCYL2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SCYL2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SCYL2 Gene
Disorders for SCYL2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cataract 8, multiple types |
|
|
Search SCYL2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for SCYL2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- SCYL2
No data available for UniProtKB/Swiss-Prot and Genatlas for SCYL2 Gene
Publications for SCYL2 Gene
- Clathrin-dependent association of CVAK104 with endosomes and the trans-Golgi network. (PMID: 16914521) Duewel M. … Ungewickell E.J. (Mol. Biol. Cell 2006) 3 4 22 64
- CVAK104 is a novel poly-L-lysine-stimulated kinase that targets the beta2-subunit of AP2. (PMID: 15809293) Conner S.D. … Schmid S.L. (J. Biol. Chem. 2005) 2 3 4 64
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 64
- CVAK104 is a novel regulator of clathrin-mediated SNARE sorting. (PMID: 17587408) Borner G.H. … Robinson M.S. (Traffic 2007) 2 3 64
- Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly. (PMID: 16903783) Schmid E.M. … McMahon H.T. (PLoS Biol. 2006) 3 4 64
Products for SCYL2 Gene
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- Custom Antibody ServicesOriGene Antibodies for SCYL2
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- Novus Biologicals Antibodies for SCYL2
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- Novus Biologicals
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- Taconic Biosciences Mouse Models for SCYL2
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for SCYL2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for SCYL2
- antibodies-online Antibodies for SCYL2: See all 44
- antibodies-online Kits for SCYL2: See all 1
- antibodies-online Proteins for SCYL2: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for SCYL2
- Search GeneTex for Proteins for SCYL2
- ViGene Biosciences adenoviral particle packaged cDNA for SCYL2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for SCYL2 gene
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- Search ViGene Biosciences for SCYL2
- Horizon Cell Lines for SCYL2
- Cyagen custom Knockout/knockin (KOKI) mouse models for SCYL2
- VectorBuilder custom plasmid, inducible vectors for SCYL2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SCYL2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for SCYL2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
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