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CCL21 Gene

protein-coding   GIFtS: 63

GC09M034699
chemokine (C-C motif) ligand 21
(Previous names: small inducible cytokine subfamily A (Cys-Cys), member 21 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: SCYA21)
Services    

Aliases &
Descriptions
for CCL21

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
6Ckine 1, 2, 3
CKb9 1, 2
ECL 1, 2
MGC34555 2
OTTHUMP00000000526 2
OTTHUMP00000000527 2
OTTHUMP00000021304 2
SCYA21 2, 3, 5
SLC 1, 2, 3, 5
TCA4 1, 2
exodus-2 1, 2
Descriptions
Beta chemokine exodus-2 2, 3
Efficient Chemoattractant for Lymphocytes 2
Secondary lymphoid-tissue chemokine 3
Small-inducible cytokine A21 3
chemokine (C-C motif) ligand 21 2
secondary lymphoid tissue chemokine 2
small inducible cytokine A21 2
small inducible cytokine subfamily A (Cys-Cys), member 21 1, 2
External Ids
HGNC: 106201
Entrez Gene: 63662
UniProtKB: O005853
Ensembl: ENSG000001370777
Search outside databases for aliases for CCL21 gene

Previous GC identifers: GC09M035021 GC09M034878

Summaries
for CCL21

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for CCL21:
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are
a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC
cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the
protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is
chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or
neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of
lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine
receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member
of the cytokine family (small inducible cytokine A19). [provided by RefSeq]

UniProtKB/Swiss-Prot: CCL21_HUMAN, O00585
Function: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and
activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity
towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid
organs

Gene Wiki entry for CCL21

Genomic Location
for CCL21

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the CCL21 gene  

Entrez Gene cytogenetic band: 9p13   Ensembl cytogenetic band:  9p13.3   HGNC cytogenetic band: 9p13

CCL21 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M034699:     (about GC identifiers)

Start:
 34,699,002 bp from pter
End:
 34,700,147 bp from pter
Size:
 1,146 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000009.10  NT_008413.17  

Proteins
for CCL21

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: CCL21_HUMAN, O00585 (See protein sequence)
Recommended Name: C-C motif chemokine 21 precursor  
Size: 134 amino acids; 14646 Da
Subunit: Binds to CCR7
Subcellular location: Secreted

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_002980.1  

    ENSEMBL proteins: 
    ENSP00000368069 ENSP00000259607 


    Human Recombinant Proteins 
    Invitrogen human recombinant proteins for CCL21
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    R&D Systems Recombinant & Natural Proteins for CCL21 (CCL21/6Ckine)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Exodus 2, CCL21)
    Human Recombinant Proteins from Abnova (CCL21)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576 extracellular region IEA--
    GO:0005615 extracellular space IEA--
    About this table

    Antibodies for CCL21: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for CCL21
    R&D Systems Antibodies for CCL21 (CCL21/6Ckine)
    Antibodies from Abcam (Exodus 2, CCL21), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (CCL21)
    Novus Biologicals Antibody for CCL21

    Assays for CCL21: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    R&D Systems ELISAs for CCL21 (CCL21/6Ckine)         (see all)
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for CCL21

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro domains/families:
     IPR000827 CC_chemkine_sml_CS
     IPR001811 Chemokine_IL8


       GeneDecks  CCL21 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry O00585

    ProtoNet protein and cluster: O00585

    1 Blocks protein family: IPB000827 Small chemokine

    UniProtKB/Swiss-Prot: CCL21_HUMAN, O00585
    Similarity: Belongs to the intercrine beta (chemokine CC) family

    Gene Function
    for CCL21

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (CCL21)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002989

                  Applied Biosystems Silencer® siRNAs for CCL21

                  Sigma-Aldrich siRNA and siRNA Panels for CCL21  
                         Sigma-Aldrich shRNA for CCL21  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for CCL21
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_002989
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_002989
                                     untagged cDNA clone in CMV expression vector: NM_002989 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_002989

    UniProtKB/Swiss-Prot: CCL21_HUMAN, O00585
    Function: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and
    activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity
    towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid
    organs

    1 Gene Ontology (GO) molecular function term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008009 chemokine activity TAS10861057
    About this table

    Pathways & Interactions
    for CCL21

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Millipore Pathway for CCL21
     Apoptosis and survival Lymphotoxin-beta receptor signaling

       GeneDecks  CCL21 for the pathways selected above  
    About GeneDecksing

    1 Sigma-Aldrich "Your Favorite Gene" Pathway for  CCL21  (Your Favorite Gene powered by Ingenuity) 
     Hepatic Fibrosis / Hepatic Stellate Cell Activation

       GeneDecks  CCL21 for the pathways selected above  
    About GeneDecksing

    1 Kegg Pathway  (Kegg details for CCL21):
     hsa04060 Cytokine-cytokine receptor interaction

       GeneDecks  CCL21 for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  CCL21 


    5/52 Interacting proteins for CCL21 (O005852 ENSP000002596073) via UniProtKB, MINT, and/or STRING (see all 52 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBQLN4Q9NRR52MINT-2862960
    CCR7ENSP000002466573STRING (score=.999)
    CXCL13ENSP000002867583STRING (score=.987)
    CXCR4ENSP000002413933STRING (score=.979)
    CXCR5ENSP000002921743STRING (score=.979)
    About this table

    5 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006935 chemotaxis TAS10861057
    GO:0006954 inflammatory response TAS9235955
    GO:0006955 immune response TAS10861057
    GO:0007165 signal transduction NAS10201891
    GO:0007267 cell-cell signaling TAS9235955
    About this table

    Drugs & Compounds
    for CCL21

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for CCL21
    8 Novoseek chemical compound relationships for CCL21 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    mip-3beta 84.50 2 12437666 (2)
    teck 76.87 5 10706668 (3), 9886241 (1), 10967023 (1)
    larc 72.91 6 9365118 (2), 10027395 (2), 10967023 (1)
    tarc 60.16 5 9365118 (2), 15890946 (2)
    ccl3 59.72 4 15818740 (1), 12651610 (1), 16106219 (1)
    rantes 50.57 7 15818740 (1), 12847218 (1), 15233729 (1), 12667214 (1) (see all 5)
    ccl4 25.79 4 12651610 (1), 16106219 (1), 18250572 (1)
    calcium 0.00 6 9507024 (3), 10339465 (2), 15956285 (1)
    About this table


    Transcripts
    for CCL21

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (CCL21)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002989

                  Sigma-Aldrich siRNA and siRNA Panels for CCL21  
                         Sigma-Aldrich shRNA for CCL21  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_002989  

    REFSEQ mRNAs for CCL21 gene: 

    NM_002989.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_002989  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_002989
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_002989
                                     untagged cDNA clone in CMV expression vector: NM_002989 

    Additional cDNA sequence: 

    AB002409.1 AF001979.1 AK311901.1 AY358887.1 BC027918.1 CR450326.1 CR615435.1 U88320.1 

    2 DOTS entries:

    DT.414858  DT.100748260 

    24/118 AceView cDNA sequences (see all 118 ):

    AA331228 AY358887 AI571892 AI253634 BI834167 AI143228 CR615435 BI838571 
    AA360283 AI707832 CR450326 AI253757 AA360212 AI718192 AI707973 BI837774 
    AA234005 BM704701 AI719947 AA027315 CF530057 CB164244 AI718256 BC027918 

    highest scoring ESTs for CCL21:

    AB002409 AA027314 AA149456 AA297977 AA298031 AA302819 AF001979 AL553486 AL553510 AY358887 

    Unigene Cluster for CCL21:

    Chemokine (C-C motif) ligand 21
    Hs.57907  [show with all ESTs]
    Unigene Representative Sequence: BI838628


    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CCL21

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
    SP1:                                    
    SP2:                                    

    About this scheme

    ECgene alternative splicing isoforms for CCL21

    2 Ensembl transcripts including schematic representations:
    ENST00000378792  ENST00000259607  

    Expression
    for CCL21

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    CCL21 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for CCL21

    1 / 2 / 3

    3 probe-sets matching CCL21 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    36503_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 AB002409 1.00 1.00 1.00 1

    		204606_at2, 3 U133-A 1 1.00 1.00 -- -- NM_002989 0.60 1.00 0.82 1

    		204606_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  CCL21 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: AGAGGAGGCA

    SOURCE GeneReport for Unigene cluster: Hs.57907

    Expression variation in blood from EXPOLDB for CCL21

    UniProtKB/Swiss-Prot: CCL21_HUMAN, O00585
    Tissue specificity: Highly expressed in high endothelial venules of lymph nodes, spleen and
    appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level
    expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and
    fetal spleen

    Orthologs
    for CCL21

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for CCL21 gene from 4 species
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    chimpanzee
    (Pan troglodytes)    		 CCL211   -- chemokine (C-C motif) ligand 21 100(n)
    100(a)    		 746205  XM_001164162.1  XP_001164162.1 
    cow
    (Bos taurus)    		 CCL211   -- chemokine (C-C motif) ligand 21 84.22(n)
    73.28(a)    		 511112  NM_001038076.1  NP_001033165.1 
    rat
    (Rattus norvegicus)    		 Ccl21b1   -- chemokine (C-C motif) ligand 21b (serine) 78.21(n)
    69.23(a)    		 298006  NM_001008513.1  NP_001008513.1 
    mouse
    (Mus musculus)    		 OTTMUSG000000113501   -- predicted gene, OTTMUSG00000011350 79.95(n)
    71.43(a)    		 100042544  XM_001478610.1  XP_001478660.1 
    About this table        Species with no ortholog for CCL21

    ENSEMBL Gene Tree for CCL21

    Paralogs
    for CCL21

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for CCL21 gene
    CCL192  

    SNPs/Variants
    for CCL21

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/21 NCBI SNPs in CCL21 are shown (see all 21 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 27)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 9 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs28123771,2
    		A,C,F,H34700450(-) ACAATT/GTAATA 1 -- ng314Minor allele frequency- G:0.25EA WA NA 324
    rs28123781,2
    		C,F,H,O34700260(-) GTCCAC/TTTAGT 1 -- ng3113Minor allele frequency- (INDETERMINATE):0.00NA EU EA WA 1044
    rs109722031,2
    		A,C,F,H34698899(-) TGTTCT/CCATCT 1 -- ng5115Minor allele frequency- C:0.11NA EU EA WA 1242
    rs115749141,2
    		C,F,H34700338(-) AGTAGC/TTGGGA 1 -- ng319Minor allele frequency- (INDETERMINATE):0.00NA EU EA WA 646
    rs109722041,2
    		C,F,H34698946(-) GGTGGG/AGTCAC 1 -- ng516Minor allele frequency- A:0.11NA EU EA WA 496
    rs115749151,2
    		C,F,H34700084(-) CCTCTG/TACTCA 1 -- ut51 ese39Minor allele frequency- (INDETERMINATE):0.00NA EU EA WA 636
    rs115749161,2
    		C,F,H34699239(-) ACCACC/TCCATC 1 -- ut31 ese36Minor allele frequency- T:0.03NA EU EA WA 504
    rs18019371,2
    		C34699060(-) CCTCTT/GCCTTG 1 -- ut311Minor allele frequency- G:0.02NA 44
    --
    rs108141361,2
    		A34701061(+) TCAATA/GGTATA 1 -- ng310--------
    --
    rs125541201,2
    		C34700538(+) tggctC/Tactga 1 -- ng31 tfbs30--------
    About this table

    HapMap Linkage Disequilibrium images for CCL21 (up to first 250kb)

    Disorders & Mutations
    for CCL21

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 602737

    10/17 Novoseek disease relationships for CCL21 gene (see all 17 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    sjogrens syndrome 27.01 1 18354239 (1)
    melanoma b16 25.89 1 16112911 (1)
    autoimmune diseases 23.77 2 12393410 (1), 16887149 (1)
    tumors 22.08 13 14613584 (2), 14726959 (1), 15059899 (1), 17016763 (1) (see all 12)
    inflammation 18.73 6 17982129 (1), 16118351 (1), 11943728 (1), 14517790 (1) (see all 5)
    atherosclerotic plaque 15.32 1 10027395 (1)
    metastasis 14.68 2 17891505 (1)
    necrosis 8.58 4 12186835 (1), 16106219 (1), 17223654 (1), 16618517 (1)
    multiple sclerosis 7.05 2 12576236 (1)
    cancer 6.73 3 14613584 (1), 16112911 (1), 15671487 (1)
    About this table

    Human Genome Epidemiology Navigator: CCL21 (3 documents)

    Medical News
    for CCL21

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for CCL21

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/161 PubMed articles for CCL21 gene (see all 161 ):

    Search for CCL21

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CCL21

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 6366 HGNC: 10620 AceView: CCL21 Ensembl:ENSG00000137077 euGenes: HUgn6366
    ECgene: CCL21 H-InvDB: CCL21

    Other Databases showing CCL21

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing CCL21

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for CCL21 Genetics and Cytogenetics in Oncology and Haematology
    Wikipedia http://en.wikipedia.org/wiki/CCL21

    Licensable Technologies
    for CCL21

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for CCL21

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for CCL21:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for CCL21-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for CCL21 Antibodies for CCL21
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for CCL21 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (CCL21)
     Antibodies (CCL21)
     Search for Chimera RNAi
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (Exodus 2, CCL21)
     Antibodies (Exodus 2, CCL21)
     Search OriGene for CCL21
     Search Tocris compounds for CCL21




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for CCL21

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