SCUBE1 Gene
protein-coding GIFtS: 49
GCID: GC22M043599
|
|
signal peptide, CUB domain, EGF-like 1
| |
Aliases for SCUBE1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Signal Peptide, CUB Domain, EGF-Like 11 2 | | Signal Peptide, CUB And EGF-Like Domain-Containing Protein 12 | | Signal Peptide-CUB Domain-EGF-Related 12 |
Export aliases for SCUBE1 gene to outside databasesPrevious GC identifers: GC22U990211 GC22M040206 GC22M041830 GC22M041924 GC22M026558 |
Summaries for SCUBE1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SCUBE1: This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermalgrowth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-likerepeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells andmay play an important role in vascular biology. (provided by RefSeq, Oct 2011) UniProtKB/Swiss-Prot: SCUB1_HUMAN, Q8IWY4Function: Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role invascular biology
|
Genomic Views for SCUBE1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SCUBE1 gene promoter: AREB6 CBF-B RREB-1 HOXA5 Lmo2 STAT3 MyoD HNF-4alpha2 HNF-4alpha1 Other transcription factors
Search SABiosciences Chromatin IP Primers for SCUBE1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCUBE1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13 Ensembl cytogenetic band: 22q13.2 HGNC cytogenetic band: 22q13SCUBE1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M043599: view genomic region
(about GC identifiers)
Start:
|
43,599,229 bp from pter |
End:
|
43,739,394 bp from pter |
Size:
|
140,166 bases |
Orientation:
|
minus strand |
|
Proteins for SCUBE1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SCUB1_HUMAN, Q8IWY4 (See
protein sequence)Recommended Name: Signal peptide, CUB and EGF-like domain-containing protein 1 precursor Size: 988 amino acids; 107910 Da
Subunit: Forms homooligomers and heterooligomers with SCUBE2 and SCUBE3 (By similarity)
Subcellular location: Secreted. Cell membrane; Peripheral membrane protein
Secondary accessions: Q5R336Explore the universe of human proteins at neXtProt for SCUBE1: NX_Q8IWY4
Post-translational modifications:
N-glycosylated1
Could be proteolytically cleaved to release a smaller active fragment1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IWY4 SCUBE1 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_766638.2 ENSEMBL proteins: ENSP00000354080 ENSP00000395327 ENSP00000290460 Human Recombinant Protein Products for SCUBE1:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SCUBE1 for ontologies About GeneDecksing
SCUBE1 Antibody Products: Assay Products for SCUBE1: |
Protein
Domains / Families for SCUBE1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SCUBE1 for domains About GeneDecksing
5/10 InterPro domains/families (see all 10):Graphical View of Domain Structure for InterPro Entry Q8IWY4ProtoNet protein and cluster: Q8IWY4 3 Blocks protein families: IPB000152 Aspartic acid and asparagine hydroxylation site IPB000859 CUB domain IPB001881 EGF-like calcium-binding
UniProtKB/Swiss-Prot: SCUB1_HUMAN, Q8IWY4Similarity: Contains 1 CUB domainSimilarity: Contains 9 EGF-like domains |
Function for SCUBE1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: SCUB1_HUMAN, Q8IWY4Function: Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role invascular biologyInduction: Down-regulated by inflammatory cytokines Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SCUBE1 for ontologies About GeneDecksing
Phenotypes: 5 GenomeRNAi human phenotypes for SCUBE1: 5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Scube1):
SCUBE1 for phenotypes About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCUBE1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCUBE1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SCUBE1 (NM_173050) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCUBE1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCUBE1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCUBE1 |
|
Pathways & Interactions for SCUBE1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SCUBE1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
 2 Interacting proteins for SCUBE1 (Q8IWY43 ENSP000003540804) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
SCUBE1 for ontologies About GeneDecksing
|
Drugs & Compounds for SCUBE1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SCUBE1 Search CenterWatch for drugs/clinical trials and news about SCUBE1 / SCUB1 
|
Transcripts for SCUBE1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SCUBE1 gene: NM_173050.3 Unigene Cluster for SCUBE1: Signal peptide, CUB domain, EGF-like 1 Hs.133995 [show with all ESTs]Unigene Representative Sequence: NM_1730507 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000360835(uc003bdt.2) ENST00000449304 ENST00000290460(uc003bdu.2) ENST00000477991 ENST00000470433 ENST00000461595 ENST00000480833
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCUBE1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCUBE1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SCUBE1 (NM_173050) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCUBE1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCUBE1  |
Additional cDNA sequence: AF525689.1 AK127719.1 BC047916.1 BC127263.1 4 DOTS entries: DT.40270980 DT.100686589 DT.120646291 DT.40271245 24/41 AceView cDNA sequences (see all 41): BG204935 BF724346 BQ183912 CB162773 BU736772 BG191628 H55062 H55691 BU101645 BM704709 BX280767 BM694185 H55345 AK127719 BQ716946 BU101912 BM714681 BF724347 NM_173050 BU101646 BC047916 BU101851 AF525689 BU101852 GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for SCUBE1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 22 | ^ | 23a | · | 23b | |
| SP1: | |   | |   | |   | |
| SP2: | |   | |   | |   | |
| SP3: | |   | |   | |   |
ECgene alternative splicing isoforms for SCUBE1
|
Expression for SCUBE1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SCUBE1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AGCCCAGTGA
 About this image See SCUBE1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SCUBE1
SOURCE GeneReport for Unigene cluster: Hs.133995
UniProtKB/Swiss-Prot: SCUB1_HUMAN, Q8IWY4Tissue specificity: Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules,and transferred to the cell surface upon activation and aggregation. A smaller form, probably produced by limitedproteolysis, after being released from the storage granules, is associated with thrombus and localized with thesubendothelial matrices in atherosclerotic plaques SABiosciences Expression via Pathway-Focused PCR Array including SCUBE1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCUBE1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SCUBE1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCUBE1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCUBE1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCUBE1 |
Orthologs for SCUBE1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SCUBE1 gene from 6/19 species (see all 19) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
SCUBE11 |
signal peptide, CUB domain, EGF-like 1 |
75.32(n) 86.24(a) |
  |
418228 XM_416453.2 XP_416453.2 |
lizard (Anolis carolinensis) |
Reptilia |
SCUBE16-- |
-- |
82(a)1(a) |
1 ↔ 1possible ortholog |
5(86502695-86708147) AAWZ02039088(481-7051) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.151052 |
Xenopus laevis transcribed sequence with moderate similarity more |
77.07(n) |
  |
CF519900.1 |
zebrafish (Danio rerio) |
Actinopterygii |
scube11 |
signal peptide, CUB domain, EGF-like 1 |
71.15(n) 77.67(a) |
  |
797832 XM_003198239.1 XP_003198287.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
dp6 |
dumpy |
|
1 → many |
2L(4477462-4595054) |
worm (Caenorhabditis elegans) |
Secernentea |
mec-96 |
MEChanosensory abnormality family member (mec-9) |
9(a) |
1 → many |
V(9907608-9915063) |
ENSEMBL Gene Tree for SCUBE1 (if available) TreeFam Gene Tree for SCUBE1 (if available)  |
Paralogs for SCUBE1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SCUBE1 gene
- FBN12 LTBP32 SCUBE32 FBN32 FBLN52 FBN22 LTBP42 EFEMP12
- EFEMP22 LTBP22 LTBP12 FBLN22 FBLN12 SCUBE22
11 SIMAP similar genes for SCUBE1 using alignment to 5 protein entries: SCUB1_HUMAN (see all proteins):DKFZp686B09105 SCUBE2 DKFZp686D20108 SCUBE3 F9 PROS1 PROC NRP2 F7 NRP1 EFEMP1
SCUBE1 for paralogs About GeneDecksing
|
Genomic Variants for SCUBE1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 22 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SCUBE1 (43599229 - 43739394 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 26 variations for SCUBE1 14 CNVs: 79595 91077 79593 91076 50871 91078 73833 79594 79597 79592 103185 91082 79596 7352 12 Indels: 91079 43196 42532 27061 79590 46231 91080 27062 79591 46232 91081 91075  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCUBE1 |
|
Disorders
/ Diseases for SCUBE1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SCUBE1 for disorders About MalaCards
SCUBE1 for disorders About GeneDecksing
OMIM gene information: 611746
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: SCUBE1 (1 document) Export disorders for SCUBE1 gene to outside databases
|
Publications for SCUBE1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SCUBE1 gene, integrated from 9 sources (see all 12): (articles sorted by number of sources associating them with SCUBE1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1). (PubMed id 11087664)1, 3, 9 Grimmond S....Greenfield A. (2000)
- Localization and characterization of a novel secreted protein SCUBE1 in human platelets. (PubMed id 16753137)1, 2 Tu C.-F.... Yang R.-B. (2006)
- Identification of a novel family of cell-surface proteins expressed in human vascular endothelium. (PubMed id 12270931)1, 2 Yang R.-B.... Topper J.N. (2002)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- A targeted association study in systemic lupus erythe matosus identifies multiple susceptibility alleles. (PubMed id 20962850)1 Budarf M.L....Rioux J.D. (2010)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
- A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones. (PubMed id 15234972)1 Wu B.-T....Yang R.-B. (2004)
- Bridging expressed sequence alignments through targeted cDNA sequencing. (PubMed id 15028280)1 Xie H....Gill-More R. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries. (PubMed id 11597177)1 Kumar S....Lark M.W. (2001)
|
External Searches for SCUBE1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SCUBE1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SCUBE1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SCUBE1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SCUBE1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SCUBE1 gene: Search GeneIP for patents involving SCUBE1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SCUBE1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SCUBE1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SCUBE1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCUBE1 | | OriGene Protein Over-expression Lysate for SCUBE1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SCUBE1 | | OriGene 3'-UTR Clone for SCUBE1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCUBE1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCUBE1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SCUBE1 | | OriGene Custom Protein Services for SCUBE1 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SCUBE1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCUBE1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCUBE1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SCUBE1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCUBE1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCUBE1 |
| |
 |  |  |  | |
| | | Search Tocris compounds for SCUBE1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | SCUBE1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCUBE1 |
|  |  |  |  | | | ThermoFisher Antibodies for SCUBE1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCUBE1 |
| |  | |
|
|
|