Aliases for SCUBE1 Gene
External Ids for SCUBE1 Gene
Previous GeneCards Identifiers for SCUBE1 Gene
This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011]
GeneCards Summary for SCUBE1 Gene
SCUBE1 (Signal Peptide, CUB Domain And EGF Like Domain Containing 1) is a Protein Coding gene. Diseases associated with SCUBE1 include testicular disease. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is CD93.
UniProtKB/Swiss-Prot for SCUBE1 Gene
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.