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SCPEP1 Gene

protein-coding   GIFtS: 56
GCID: GC17P055055

Serine Carboxypeptidase 1

  See SCPEP1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Serine Carboxypeptidase 11 2 3     Serine Carboxypeptidase 1 Precursor Protein2
Retinoid Inducible Serine Carboxypeptidase1 2     EC 3.4.16.-3
RISC2 3     SCP13
HSCP12     EC 3.4.168
Retinoid-Inducible Serine Carboxypeptidase2     

External Ids:    HGNC: 295071   Entrez Gene: 593422   Ensembl: ENSG000001210647   UniProtKB: Q9HB403   

Export aliases for SCPEP1 gene to outside databases

Previous GC identifers: GC17P055531 GC17P052410 GC17P050416


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SCPEP1 Gene:
SCPEP1 (serine carboxypeptidase 1) is a protein-coding gene. Diseases associated with SCPEP1 include retinal perforation. GO annotations related to this gene include serine-type carboxypeptidase activity.

UniProtKB/Swiss-Prot: RISC_HUMAN, Q9HB40
Function: May be involved in vascular wall and kidney homeostasis (By similarity)

Gene Wiki entry for SCPEP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SCPEP1 gene promoter:
         TBP   Elk-1   AP-1   E47   C/EBPalpha   PPAR-alpha   Hand1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCPEP1 promoter sequence
   Search Chromatin IP Primers for SCPEP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCPEP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q22   Ensembl cytogenetic band:  17q22   HGNC cytogenetic band: 17q22

SCPEP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCPEP1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P055055:  view genomic region     (about GC identifiers)

Start:
55,055,466 bp from pter      End:
55,084,129 bp from pter
Size:
28,664 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RISC_HUMAN, Q9HB40 (See protein sequence)
Recommended Name: Retinoid-inducible serine carboxypeptidase precursor  
Size: 452 amino acids; 50831 Da
Secondary accessions: Q96A94 Q9H3F0
Alternative splicing: 2 isoforms:  Q9HB40-1   Q9HB40-2   (No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for SCPEP1: NX_Q9HB40

Explore proteomics data for SCPEP1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys243
  • Glycosylation2 at Asn64, Asn126, Asn362
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for SCPEP1 (Q9HB40)
     PVGTGFS  LGDSWISP 


    See SCPEP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_067639.1  
    ENSEMBL proteins: 
     ENSP00000262288   ENSP00000458671   ENSP00000459807   ENSP00000461663   ENSP00000461694  
     ENSP00000458587   ENSP00000461678  

    SCPEP1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SCPEP1

     
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    antibodies-online proteins for SCPEP1 (3 products) 

     
    Search antibodies-online for peptides for SCPEP1

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    antibodies-online antibodies for SCPEP1 (16 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: Serine carboxypeptidase 1
    Serine-type carboxypeptidases

    2 InterPro protein domains:
     IPR018202 Peptidase_S10_AS
     IPR001563 Peptidase_S10

    Graphical View of Domain Structure for InterPro Entry Q9HB40

    ProtoNet protein and cluster: Q9HB40

    1 Blocks protein domain: IPB001563 Serine carboxypeptidase (S10)

    UniProtKB/Swiss-Prot: RISC_HUMAN, Q9HB40
    Similarity: Belongs to the peptidase S10 family


    Find genes that share domains with SCPEP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RISC_HUMAN, Q9HB40
    Function: May be involved in vascular wall and kidney homeostasis (By similarity)

         Enzyme Numbers (IUBMB): EC 3.4.16.-1 EC 3.4.162

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004185serine-type carboxypeptidase activity IEA--
         
    Find genes that share ontologies with SCPEP1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SCPEP1:
     Increased gamma-H2AX phosphory 

         3 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Scpep1):
     cardiovascular system  homeostasis/metabolism  normal 

    Find genes that share phenotypes with SCPEP1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for SCPEP1: Scpep1tm1Lex Scpep1tm1Jomm

       genOway: Develop your customized and physiologically relevant rodent model for SCPEP1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RISC_HUMAN, Q9HB40: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    cytosol2
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005829cytosol IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with SCPEP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SCPEP1
    Interactions:

        Search GeneGlobe Interaction Network for SCPEP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SCPEP1 (Q9HB403 ENSP000002622884) via UniProtKB, MINT, STRING, and/or I2D (see all 44)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SLC2A4P146723I2D: score=1 
    MLST8ENSP000003718884STRING: ENSP00000371888
    MORF4L1ENSP000003313104STRING: ENSP00000331310
    JMJD6ENSP000003940854STRING: ENSP00000394085
    NDUFS1ENSP000002331904STRING: ENSP00000233190
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----
    GO:0042573retinoic acid metabolic process IEA--

    Find genes that share ontologies with SCPEP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SCPEP1 (RISC)

    1 DrugBank Compound for SCPEP1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-BENZYLSUCCINIC ACID-- --target--10592235



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SCPEP1 gene: 
    NM_021626.2  

    Unigene Cluster for SCPEP1:

    Serine carboxypeptidase 1
    Hs.514950  [show with all ESTs]
    Unigene Representative Sequence: NM_021626
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262288(uc002iuv.4 uc010dcl.3 uc010wnk.2) ENST00000575423
    ENST00000571345 ENST00000572591 ENST00000572710 ENST00000575395 ENST00000573823
    ENST00000576154 ENST00000571898 ENST00000570480 ENST00000570589 ENST00000573789
    ENST00000570505 ENST00000573239 ENST00000570479
    miRNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SCPEP1
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    GenScript: all cDNA clones in your preferred vector: SCPEP1 (NM_021626)
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCPEP1
      QuantiTect SYBR Green Assays in human, mouse, rat SCPEP1
      QuantiFast Probe-based Assays in human, mouse, rat SCPEP1

    Additional mRNA sequence: 

    AF113214.1 AF265441.1 AF282618.1 AK027373.1 AY358559.1 BC072405.1 

    15 DOTS entries:

    DT.408355  DT.100680553  DT.97845249  DT.100811079  DT.100811073  DT.95084513  DT.100642302  DT.100811078 
    DT.40249764  DT.97845248  DT.120993424  DT.92437560  DT.95240271  DT.40245153  DT.95240275 

    Selected AceView cDNA sequences (see all 255):

    CR609709 BG168862 BX380101 BQ918338 CA413020 AA576835 BP345163 BM547744 
    AI860829 BX439449 AI687454 BP372881 CD370400 BP355303 BE907605 AI567506 
    AA701457 AI758346 BM788611 BP338281 BP376600 BI772479 BP345578 BF929412 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SCPEP1 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c · 11d ^ 12a · 12b ^ 13 ^ 14a · 14b · 14c ·
    SP1:                          -                       -                                   -     -     -     -                                                   
    SP2:                          -                       -                                   -     -     -                                                         
    SP3:                                                                                                                                                            
    SP4:                                                                                      -     -     -     -           -     -                                 
    SP5:                                                                                                                                                            

    ExUns: 14d
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for SCPEP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SCPEP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAATAAATG
    SCPEP1 Expression
    About this image


    SCPEP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 12) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Blood (Hematopoietic System)
             Monocytes Peripheral Blood
     
     Kidney (Urinary System)
     
     Thyroid (Endocrine System)
     
     Lung (Respiratory System)
    SCPEP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SCPEP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.514950
        Custom PCR Arrays for SCPEP1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCPEP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SCPEP1 gene from Selected species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scpep11 , 5 serine carboxypeptidase 11, 5 82.15(n)1
    82.3(a)1
      11 (54.34 cM)5
    746171  NM_029023.31  NP_083299.31 
     889240205 
    chicken
    (Gallus gallus)
    Aves SCPEP11 serine carboxypeptidase 1 69.6(n)
    68.88(a)
      417403  NM_001012803.1  NP_001012821.1 
    lizard
    (Anolis carolinensis)
    Reptilia SCPEP16
    serine carboxypeptidase 1
    67(a)
    1 ↔ 1
    GL343198.1(700258-729171)
    African clawed frog
    (Xenopus laevis)
    Amphibia BG347881.12   -- 87.37(n)    BG347881.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC045898.12   -- 77.23(n)   393161  BC045898.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG324831 CG32483 49.55(n)
    40.83(a)
      318050  NM_167839.2  NP_728540.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y32F6A.51 CELE_Y32F6A.5 51.35(n)
    44.96(a)
      179459  NM_001269292.1  NP_001256221.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes KEX16
    Protease involved in the processing of killer toxi...
    15(a)
    1 ↔ 1
    VII(112475-114664) YGL203C
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SCPL511 SCPL51 53.14(n)
    46.86(a)
      817336  NM_128351.3  NP_565663.1 
    rice
    (Oryza sativa)
    Liliopsida Os.77542 Oryza sativa (japonica cultivar-group) cDNA cloneJ033036J23, full insert sequence less 71.59(n)    AK119519.1 


    ENSEMBL Gene Tree for SCPEP1 (if available)
    TreeFam Gene Tree for SCPEP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SCPEP1 gene
    1 SIMAP similar gene for SCPEP1 using alignment to 6 protein entries:     RISC_HUMAN (see all proteins):
    CPVL

    Find genes that share paralogs with SCPEP1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SCPEP1 (see all 714)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs359665181,2
    C--55053538(+) CCACC-/TTGGTC 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs1508528261,2
    C--55053629(+) ACCTTC/TCCCTA 1 -- us2k10--------
    rs1843262261,2
    --55053650(+) TATGAA/CTATCA 1 -- us2k10--------
    rs1904055251,2
    --55053708(+) ATTAGC/TGTATT 1 -- us2k10--------
    rs1925312831,2
    --55053930(+) ATGTTA/GGCCAG 1 -- us2k10--------
    rs1849679551,2
    --55053953(+) CCCCCG/TACCTC 1 -- us2k10--------
    rs1381215361,2
    --55054055(+) AAAAAC/TTGAAA 1 -- us2k10--------
    rs1427837031,2
    C--55054122(+) GACCAA/GCTTGG 1 -- us2k10--------
    rs72212861,2
    C,F,H--55054154(+) TGCTAC/GATAGT 1 -- us2k1 tfbs325Minor allele frequency- G:0.13NS EA NA WA CSA 2349
    rs1460680491,2
    --55054282(+) AGCTTA/GGACAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SCPEP1 (55055466 - 55084129 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SCPEP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv32884CNV Loss17666407

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SCPEP1
    DNA2.0 Custom Variant and Variant Library Synthesis for SCPEP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for SCPEP1:    
    About MalaCards
    retinal perforation

    1 disease from the University of Copenhagen DISEASES database for SCPEP1:
    Retinal perforation

    Find genes that share disorders with SCPEP1           About GenesLikeMe


    Export disorders for SCPEP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SCPEP1 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with SCPEP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
    2. Cloning of a novel retinoid-inducible serine carboxypeptidase from vascular smooth muscle cells. (PubMed id 11447226)1, 3, 9 Chen J....Miano J.M. (J. Biol. Chem. 2001)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
    6. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)1, 2 Zhang H.... Aebersold R. (Nat. Biotechnol. 2003)
    7. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 59342 HGNC: 29507 AceView: SCPEP1 Ensembl:ENSG00000121064 euGenes: HUgn59342
    ECgene: SCPEP1 H-InvDB: SCPEP1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SCPEP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SCPEP1 gene:
    Search GeneIP for patents involving SCPEP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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