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Aliases for SCN4A Gene

Aliases for SCN4A Gene

  • Sodium Voltage-Gated Channel Alpha Subunit 4 2 3
  • Sodium Channel, Voltage Gated, Type IV Alpha Subunit 2 3 5
  • Sodium Channel, Voltage-Gated, Type IV, Alpha Subunit 2 3
  • Sodium Channel Protein Skeletal Muscle Subunit Alpha 3 4
  • Voltage-Gated Sodium Channel Subunit Alpha Nav1.4 3 4
  • Sodium Channel Protein Type IV Subunit Alpha 3 4
  • SkM1 3 4
  • Skeletal Muscle Voltage-Dependent Sodium Channel Type IV Alpha Subunit 3
  • Skeletal Muscle Sodium Channel Alpha Subunit 3
  • CTC-264K15.6 3
  • Na(V)1.4 3
  • HOKPP2 3
  • Nav1.4 3
  • CMS16 3
  • NAC1A 3
  • HYKPP 3
  • HYPP 3

External Ids for SCN4A Gene

Previous HGNC Symbols for SCN4A Gene

  • HYKPP

Previous GeneCards Identifiers for SCN4A Gene

  • GC17M061653
  • GC17M064442
  • GC17M062356
  • GC17M062489
  • GC17M059369
  • GC17M062015
  • GC17M057383

Summaries for SCN4A Gene

Entrez Gene Summary for SCN4A Gene

  • Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008]

GeneCards Summary for SCN4A Gene

SCN4A (Sodium Voltage-Gated Channel Alpha Subunit 4) is a Protein Coding gene. Diseases associated with SCN4A include paramyotonia congenita and myotonia congenita, atypical, acetazolamide-responsive. Among its related pathways are Cardiac conduction and Developmental Biology. GO annotations related to this gene include ion channel activity and voltage-gated sodium channel activity. An important paralog of this gene is CACNA1G.

UniProtKB/Swiss-Prot for SCN4A Gene

  • This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.

Tocris Summary for SCN4A Gene

  • Voltage-gated sodium channels (NaV) are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types. They are also expressed at low levels in non-excitable cells, where their physiological role is unclear.

Gene Wiki entry for SCN4A Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SCN4A Gene

Genomics for SCN4A Gene

Regulatory Elements for SCN4A Gene

Genomic Location for SCN4A Gene

Chromosome:
17
Start:
63,938,554 bp from pter
End:
63,990,150 bp from pter
Size:
51,597 bases
Orientation:
Minus strand

Genomic View for SCN4A Gene

Genes around SCN4A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCN4A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCN4A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCN4A Gene

Proteins for SCN4A Gene

  • Protein details for SCN4A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P35499-SCN4A_HUMAN
    Recommended name:
    Sodium channel protein type 4 subunit alpha
    Protein Accession:
    P35499
    Secondary Accessions:
    • Q15478
    • Q16447
    • Q7Z6B1

    Protein attributes for SCN4A Gene

    Size:
    1836 amino acids
    Molecular mass:
    208061 Da
    Quaternary structure:
    • Muscle sodium channels contain an alpha subunit and a smaller beta subunit. Interacts with the PDZ domain of the syntrophin SNTA1, SNTB1 and SNTB2 (By similarity).

neXtProt entry for SCN4A Gene

Proteomics data for SCN4A Gene at MOPED

Post-translational modifications for SCN4A Gene

  • Phosphorylation at Ser-1328 by PKC in a highly conserved cytoplasmic loop slows inactivation of the sodium channel and reduces peak sodium currents.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SCN4A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for SCN4A (SCN4A)

No data available for DME Specific Peptides for SCN4A Gene

Domains & Families for SCN4A Gene

Gene Families for SCN4A Gene

Graphical View of Domain Structure for InterPro Entry

P35499

UniProtKB/Swiss-Prot:

SCN4A_HUMAN :
  • The sequence contains 4 internal repeats, each with 5 hydrophobic segments (S1,S2,S3,S5,S6) and one positively charged segment (S4). Segments S4 are probably the voltage-sensors and are characterized by a series of positively charged amino acids at every third position.
  • Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.
Domain:
  • The sequence contains 4 internal repeats, each with 5 hydrophobic segments (S1,S2,S3,S5,S6) and one positively charged segment (S4). Segments S4 are probably the voltage-sensors and are characterized by a series of positively charged amino acids at every third position.
  • Contains 1 IQ domain.
Family:
  • Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.
genes like me logo Genes that share domains with SCN4A: view

Function for SCN4A Gene

Molecular function for SCN4A Gene

GENATLAS Biochemistry:
sodium voltage-gated channel,type IV,alpha polypeptide (see also GH),adult muscle
UniProtKB/Swiss-Prot Function:
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.
genes like me logo Genes that share phenotypes with SCN4A: view

Human Phenotype Ontology for SCN4A Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SCN4A Gene

MGI Knock Outs for SCN4A:

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Transcription Factor Targets and HOMER Transcription for SCN4A Gene

Localization for SCN4A Gene

Subcellular locations from UniProtKB/Swiss-Prot for SCN4A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SCN4A Gene COMPARTMENTS Subcellular localization image for SCN4A gene
Compartment Confidence
plasma membrane 5
nucleus 3
cytoskeleton 2
extracellular 1

Gene Ontology (GO) - Cellular Components for SCN4A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with SCN4A: view

Pathways & Interactions for SCN4A Gene

genes like me logo Genes that share pathways with SCN4A: view

Gene Ontology (GO) - Biological Process for SCN4A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006811 ion transport IEA --
GO:0006812 cation transport IEA --
GO:0006814 sodium ion transport IEA,TAS 10218481
GO:0006936 muscle contraction TAS 1338909
GO:0019228 neuronal action potential IBA --
genes like me logo Genes that share ontologies with SCN4A: view

No data available for SIGNOR curated interactions for SCN4A Gene

Drugs & Compounds for SCN4A Gene

(28) Drugs for SCN4A Gene - From: DGIdb, Novoseek, IUPHAR, Tocris, DrugBank, ApexBio, PharmGKB, and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Flecainide Approved, Withdrawn Pharma Pore Blocker, Target, inhibitor 39
Zonisamide Approved, Investigational Pharma blocker, Target, inhibitor Antiepileptic with anticonvulsant and mechanistic effect 65
Mexiletine Approved Pharma blocker 19
Propofol Approved, Investigational Pharma inhibitor, Target 931
Fospropofol Approved, Illicit Pharma 21

(10) Additional Compounds for SCN4A Gene - From: Tocris, IUPHAR, Novoseek, and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
sodium
  • Sodium
  • Sodium ion
7440-23-5
mexilitine
Antagonist, Pore Blocker
mu-conotoxin GIIIA
Antagonist, Pore Blocker
4'-Hydroxydiclofenac
  • (O-(2,6-Dichloro-4-hydroxyanilino)phenyl)acetic acid
  • 4'-Hydroxy diclofenac
  • 4'-OH DCF
  • {2-[(2,6-dichloro-4-hydroxyphenyl)amino]phenyl}acetic acid
64118-84-9
4-Hydroxypropofol

(5) Tocris Compounds for SCN4A Gene

Compound Action Cas Number
Amiloride hydrochloride Na+ channel blocker; also I2 imidazoline ligand 2016-88-8
Flunarizine dihydrochloride Dual Na+/Ca2+ channel (T-type) blocker 30484-77-6
Riluzole hydrochloride Glutamate release inhibitor/GABA uptake inhibitor 850608-87-6
Veratridine Voltage-gated Na+ channel opener 71-62-5
Vinpocetine Na+ channel blocker 42971-09-5

(1) ApexBio Compounds for SCN4A Gene

Compound Action Cas Number
β-Pompilidotoxin Slows Na+ channel inactivation 216064-36-7
genes like me logo Genes that share compounds with SCN4A: view

Transcripts for SCN4A Gene

mRNA/cDNA for SCN4A Gene

Unigene Clusters for SCN4A Gene

Sodium channel, voltage-gated, type IV, alpha subunit:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SCN4A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b ^
SP1: - -
SP2:
SP3: - - - - -
SP4:
SP5:

ExUns: 20 ^ 21 ^ 22 ^ 23 ^ 24
SP1:
SP2:
SP3:
SP4:
SP5:

Relevant External Links for SCN4A Gene

GeneLoc Exon Structure for
SCN4A
ECgene alternative splicing isoforms for
SCN4A

Expression for SCN4A Gene

mRNA expression in normal human tissues for SCN4A Gene

mRNA differential expression in normal tissues according to GTEx for SCN4A Gene

This gene is overexpressed in Muscle - Skeletal (x32.1), Adipose - Visceral (Omentum) (x5.6), and Adipose - Subcutaneous (x4.0).

SOURCE GeneReport for Unigene cluster for SCN4A Gene Hs.46038

genes like me logo Genes that share expression patterns with SCN4A: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SCN4A Gene

Orthologs for SCN4A Gene

This gene was present in the common ancestor of animals.

Orthologs for SCN4A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SCN4A 35
  • 91.31 (n)
  • 93.66 (a)
SCN4A 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SCN4A 35
  • 90.4 (n)
  • 94.7 (a)
SCN4A 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Scn4a 35
  • 88.54 (n)
  • 92.45 (a)
Scn4a 16
Scn4a 36
  • 92 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SCN4A 35
  • 97.32 (n)
  • 96.93 (a)
SCN4A 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Scn4a 35
  • 88.91 (n)
  • 92.78 (a)
oppossum
(Monodelphis domestica)
Mammalia SCN4A 36
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves SCN4A 35
  • 79.03 (n)
  • 81.76 (a)
SCN4A 36
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SCN4A 36
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100492371 35
  • 69.93 (n)
  • 78.22 (a)
zebrafish
(Danio rerio)
Actinopterygii scn4aa 35
  • 69.94 (n)
  • 74.37 (a)
scn4aa 36
  • 69 (a)
OneToMany
scn4ab 36
  • 68 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta NaCP37B 37
  • 55 (a)
NaCP60E 37
  • 62 (a)
para 37
  • 50 (a)
Species with no ortholog for SCN4A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SCN4A Gene

ENSEMBL:
Gene Tree for SCN4A (if available)
TreeFam:
Gene Tree for SCN4A (if available)

Paralogs for SCN4A Gene

genes like me logo Genes that share paralogs with SCN4A: view

Variants for SCN4A Gene

Sequence variations from dbSNP and Humsavar for SCN4A Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
VAR_001560 -
VAR_001561 -
VAR_001562 Paramyotonia congenita of von Eulenburg (PMC)
VAR_001562 Periodic paralysis hyperkalemic (HYPP)
VAR_001563 Paramyotonia congenita of von Eulenburg (PMC)

Structural Variations from Database of Genomic Variants (DGV) for SCN4A Gene

Variant ID Type Subtype PubMed ID
nsv517272 CNV Gain+Loss 19592680
nsv833511 CNV Loss 17160897
nsv908684 CNV Loss 21882294
nsv820272 CNV Loss 19587683
nsv470596 CNV Loss 18288195
esv999259 CNV Loss 20482838
nsv908685 CNV Loss 21882294

Variation tolerance for SCN4A Gene

Residual Variation Intolerance Score: 49.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.46; 64.16% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SCN4A Gene

HapMap Linkage Disequilibrium report
SCN4A
Human Gene Mutation Database (HGMD)
SCN4A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SCN4A Gene

Disorders for SCN4A Gene

MalaCards: The human disease database

(28) MalaCards diseases for SCN4A Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
paramyotonia congenita
  • pyruvate carboxylase deficiency disease
myotonia congenita, atypical, acetazolamide-responsive
  • hyperkalemic periodic paralysis
hypokalemic periodic paralysis, type 2
  • hypokalemic periodic paralysis type 2
myasthenic syndrome, congenital, 16
  • congenital myasthenic syndrome due to mutation in scn4a
hyperkalemic periodic paralysis, type 2
  • hyperkalemic periodic paralysis
- elite association - COSMIC cancer census association via MalaCards
Search SCN4A in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

SCN4A_HUMAN
  • Myasthenic syndrome, congenital, 16 (CMS16) [MIM:614198]: A form of congenital myasthenic syndrome, a group of disorders characterized by failure of neuromuscular transmission, including pre-synaptic, synaptic, and post-synaptic disorders that are not of autoimmune origin. Clinical features are easy fatigability and muscle weakness. CMS16 is characterized by fatigable generalized weakness and recurrent attacks of respiratory and bulbar paralysis since birth. The fatigable weakness involves lid-elevator, external ocular, facial, limb and truncal muscles and an decremental response of the compound muscle action potential on repetitive stimulation. {ECO:0000269 PubMed:12766226, ECO:0000269 PubMed:25707578, ECO:0000269 PubMed:26659129, ECO:0000269 PubMed:26700687}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Myotonia SCN4A-related (MYOSCN4A) [MIM:608390]: A phenotypically highly variable myotonia aggravated by potassium loading, and sometimes by cold. Myotonia is characterized by sustained muscle tensing that prevents muscles from relaxing normally. It causes muscle stiffness that can interfere with movement. In some people the stiffness is very mild, while in other cases it may be severe enough to interfere with walking, running, and other activities of daily life. Myotonia SCN4A-related includes myotonia permanens and myotonia fluctuans. In myotonia permanens, the myotonia is generalized and there is a hypertrophy of the muscle, particularly in the neck and the shoulder. Attacks of severe muscle stiffness of the thoracic muscles may be life threatening due to impaired ventilation. In myotonia fluctuans, the muscle stiffness may fluctuate from day to day, provoked by exercise. {ECO:0000269 PubMed:10218481, ECO:0000269 PubMed:16786525, ECO:0000269 PubMed:16832098, ECO:0000269 PubMed:17212350, ECO:0000269 PubMed:17998485, ECO:0000269 PubMed:18203179, ECO:0000269 PubMed:18337100, ECO:0000269 PubMed:19015483, ECO:0000269 PubMed:19347921, ECO:0000269 PubMed:20076800, ECO:0000269 PubMed:8058156, ECO:0000269 PubMed:9392583}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Paramyotonia congenita of von Eulenburg (PMC) [MIM:168300]: An autosomal dominant channelopathy characterized by myotonia, increased by exposure to cold, intermittent flaccid paresis, not necessarily dependent on cold or myotonia, lability of serum potassium, non-progressive nature and lack of atrophy or hypertrophy of muscles. In some patients, myotonia is not increased by cold exposure (paramyotonia without cold paralysis). Patients may have a combination phenotype of PMC and HYPP. {ECO:0000269 PubMed:10369308, ECO:0000269 PubMed:10727489, ECO:0000269 PubMed:1310898, ECO:0000269 PubMed:1316765, ECO:0000269 PubMed:1338909, ECO:0000269 PubMed:15318338, ECO:0000269 PubMed:15790667, ECO:0000269 PubMed:16786525, ECO:0000269 PubMed:18166706, ECO:0000269 PubMed:19077043, ECO:0000269 PubMed:20076800, ECO:0000269 PubMed:8242056, ECO:0000269 PubMed:8308722, ECO:0000269 PubMed:8388676, ECO:0000269 PubMed:8580427}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Periodic paralysis hyperkalemic (HYPP) [MIM:170500]: An autosomal dominant channelopathy characterized by episodic flaccid generalized muscle weakness associated with high levels of serum potassium. Concurrence of myotonia is found in HYPP patients. {ECO:0000269 PubMed:1659668, ECO:0000269 PubMed:1659948, ECO:0000269 PubMed:20076800, ECO:0000269 PubMed:7695243}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Periodic paralysis hypokalemic 2 (HOKPP2) [MIM:613345]: An autosomal dominant disorder manifested by episodic flaccid generalized muscle weakness associated with falls of serum potassium levels. {ECO:0000269 PubMed:10599760, ECO:0000269 PubMed:10851391, ECO:0000269 PubMed:10944223, ECO:0000269 PubMed:11558801, ECO:0000269 PubMed:11591859, ECO:0000269 PubMed:16890191, ECO:0000269 PubMed:17898326, ECO:0000269 PubMed:18162704, ECO:0000269 PubMed:19118277, ECO:0000269 PubMed:20522878, ECO:0000269 PubMed:21043388, ECO:0000269 PubMed:24549961}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Periodic paralysis normokalemic (NKPP) [MIM:170500]: A disorder closely related to hyperkalemic periodic paralysis, but marked by a lack of alterations in potassium levels during attacks of muscle weakness. {ECO:0000269 PubMed:15596759, ECO:0000269 PubMed:18046642, ECO:0000269 PubMed:20522878}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for SCN4A

Genetic Association Database (GAD)
SCN4A
Human Genome Epidemiology (HuGE) Navigator
SCN4A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SCN4A
genes like me logo Genes that share disorders with SCN4A: view

No data available for Genatlas for SCN4A Gene

Publications for SCN4A Gene

  1. Identification of a mutation in the gene causing hyperkalemic periodic paralysis. (PMID: 1659948) Ptacek L.J. … Leppert M.F. (Cell 1991) 2 3 4 23 67
  2. Homozygosity for dominant mutations increases severity of muscle channelopathies. (PMID: 19882638) Arzel-HAczode M. … Fournier E. (Muscle Nerve 2010) 3 23
  3. The antiepileptic drug zonisamide inhibits MAO-B and attenuates MPTP toxicity in mice: clinical relevance. (PMID: 19948168) Sonsalla P.K. … Buckley B. (Exp. Neurol. 2010) 25 26
  4. Zonisamide in the treatment of epilepsy. (PMID: 20001433) Schulze-Bonhage A. (Expert Opin Pharmacother 2010) 25 26
  5. Tubular aggregates in paralysis periodica paramyotonica with T704M mutation of SCN4A. (PMID: 19077043) Luan X. … Yuan Y. (Neuropathology 2009) 3 23

Products for SCN4A Gene

Sources for SCN4A Gene

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