SCN10A Gene
protein-coding GIFtS: 56
GCID: GC03M038713
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sodium channel, voltage-gated, type X, alpha subunit(Previous names: sodium channel, voltage-gated, type X, alpha polypeptide...)
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Aliases for SCN10A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Sodium Channel, Voltage-Gated, Type X, Alpha Subunit1 2 | | Sodium Channel, Voltage-Gated, Type X, Alpha Polypeptide1 2 | | PN31 2 3 | | Peripheral Nerve Sodium Channel 32 3 | | HPN31 | | Sodium Channel Protein Type X Subunit Alpha2 3 | | Nav1.81 2 | | Voltage-Gated Sodium Channel Subunit Alpha Nav1.82 3 | | SNS1 2 | | Sodium Channel Protein Type 10 Subunit Alpha2 |
Export aliases for SCN10A gene to outside databasesPrevious GC identifers: GC03U990071 GC03M038552 GC03M038699 |
Summaries for SCN10A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SCN10A: The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The propertiesof the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits.This protein may be involved in the onset of pain associated with peripheral neuropathy. (provided by RefSeq, Dec2011) UniProtKB/Swiss-Prot: SCNAA_HUMAN, Q9Y5Y9Function: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming openedor closed conformations in response to the voltage difference across the membrane, the protein forms asodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is atetrodotoxin-resistant sodium channel isoform. Its electrophysiological properties vary depending on the type of theassociated beta subunits (in vitro). Plays a role in neuropathic pain mechanisms (By similarity)
summary
for SCN10A: Voltage-gated sodium channels (NaV) are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types. They are also expressed at low levels in non-excitable cells, where their physiological role is unclear. Structurally, Nav channels are composed of one pore-forming alpha-subunit, which may be associated with either one or more beta-subunits. alpha-subunits are composed for four homologous domains, each of which contains six transmembrane segments. The fourth transmembrane loop (S4) acts as the 'voltage sensor' and is activated by changes in membrane potential. S4 is also involved in channel gating. Gene Wiki entry for SCN10A
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Genomic Views for SCN10A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SCN10A gene promoter: E2F-1 NRSF form 1 NF-kappaB1 NRSF form 2 Other transcription factors
Search SABiosciences Chromatin IP Primers for SCN10A
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCN10A |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p22.2 Ensembl cytogenetic band: 3p22.2 HGNC cytogenetic band: 3p22.2SCN10A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M038713: view genomic region
(about GC identifiers)
Start:
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38,738,293 bp from pter |
End:
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38,835,501 bp from pter |
Size:
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97,209 bases |
Orientation:
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minus strand |
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Proteins for SCN10A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SCNAA_HUMAN, Q9Y5Y9 (See
protein sequence)Recommended Name: Sodium channel protein type 10 subunit alpha Size: 1956 amino acids; 220626 Da
Subunit: The voltage-resistant sodium channel consists of an ion conducting pore forming alpha-subunit regulated by oneor more associated auxiliary subunits SCN1B, SCN2B and SCN3B. Found in a number of complexes with PRX, DYNLT1 andPDZD2. Interacts with proteins such as FSTL1, PRX, DYNLT1, PDZD2, S100A10 and many others (By similarity). Interactswith NEDD4 and NEDD4L
Subcellular location: Membrane; Multi-pass membrane protein (By similarity). Note=It can be translocated to theextracellular membrane through association with S100A10 (By similarity)
Secondary accessions: A6NDQ1Explore the universe of human proteins at neXtProt for SCN10A: NX_Q9Y5Y9
Post-translational modifications:
Ubiquitinated by NEDD4L; which promotes its endocytosis (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y5Y9 SCN10A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006505.2 ENSEMBL proteins: ENSP00000390600 Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
SCN10A for ontologies About GeneDecksing
SCN10A Antibody Products: Assay Products for SCN10A: |
Protein
Domains / Families for SCN10A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SCN10A for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y5Y9ProtoNet protein and cluster: Q9Y5Y9 1 Blocks protein family: IPB001696 Voltage-gated Na+ channel alpha subunit signature
UniProtKB/Swiss-Prot: SCNAA_HUMAN, Q9Y5Y9Domain: The sequence contains 4 internal repeats, each with 5 hydrophobic segments (S1,S2,S3,S5,S6) and one positivelycharged segment (S4). Segments S4 are probably the voltage-sensors and are characterized by a series of positivelycharged amino acids at every third positionSimilarity: Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.8/SCN10A subfamilySimilarity: Contains 1 IQ domain |
Function for SCN10A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SCNAA_HUMAN, Q9Y5Y9Function: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming openedor closed conformations in response to the voltage difference across the membrane, the protein forms asodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is atetrodotoxin-resistant sodium channel isoform. Its electrophysiological properties vary depending on the type of theassociated beta subunits (in vitro). Plays a role in neuropathic pain mechanisms (By similarity) Genatlas biochemistry entry for SCN10A:sodium channel voltage-gated,type X,alpha polypeptide,tetrodotoxin resistant,specific to sensory neurons,expressed indorsal root ganglia
Clone Products: |  | EMD Millipore Clones for the Expression of SCN10A | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCN10A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCN10A OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCN10A |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SCN10A for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SCN10A: Animal Models: Mouse knock-out Scn10atm1Jnw for SCN10A 6 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Scn10a):
SCN10A for phenotypes About GeneDecksing
|
Pathways & Interactions for SCN10A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Activation of cAMP-Dependent PKA | | | 2 | Neuropathic Pain-Signaling in Dorsal Horn Neurons | | | 3 | PKA activation in glucagon signalling | | | 4 | Synaptic transmission: ion currents | | | 5 | Sodium channels and transporters: inward current | |
Pathway sources See GeneCards unified pathways Show all pathways
3 EMD Millipore Pathways for SCN10A 5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SCN10A (see all 7) 1 GeneGo (Thomson Reuters) Pathway for SCN10A
SCN10A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SCN10A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 15)
 5/34 Interacting proteins for SCN10A (Q9Y5Y93 ENSP000003906004) via UniProtKB, MINT, STRING, and/or I2D (see all 34)About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table
SCN10A for ontologies About GeneDecksing
|
Drugs & Compounds for SCN10A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SCN10A for compounds About GeneDecksing
Compounds for SCN10A available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| A 803467 | Selective NaV1.8 blocker | [944261-79-4] | | Co 102862 | State-dependent Na+ channel blocker; anticonvulsant | [181144-66-1] | | A 887826 | Selective Nav1.8 channel blocker | [1266212-81-0] | | QX 314 chloride | Na+ channel blocker | [5369-03-9] | | Tetrodotoxin citrate | Na+ channel blocker. Citrate salt of tetrodotoxin (Cat. No. 1078) | [18660-81-6] |
2 HMDB Compounds for SCN10A About this table
10/15 DrugBank Compounds for SCN10A (see all 15) About this table
2 Novoseek chemical compound relationships for SCN10A gene About this table
Search CenterWatch for drugs/clinical trials and news about SCN10A / SCNAA 
|
Transcripts for SCN10A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SCN10A gene: NM_006514.2 Unigene Cluster for SCN10A: Sodium channel, voltage-gated, type X, alpha subunit Hs.250443 [show with all ESTs]Unigene Representative Sequence: NM_0065141 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000449082(uc003ciq.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCN10A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCN10A OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SCN10A (NM_006514) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCN10A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCN10A  |
Additional cDNA sequence: AF117907.1 1 DOTS entry: DT.91749733 3 AceView cDNA sequences: NM_006514 AF117907 AL705279 GeneLoc Exon Structure
|
Expression for SCN10A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SCN10A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See SCN10A Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SCN10A
SOURCE GeneReport for Unigene cluster: Hs.250443 UniProtKB/Swiss-Prot: SCNAA_HUMAN, Q9Y5Y9Tissue specificity: Expressed in the dorsal root ganglia and sciatic nerve SABiosciences Expression via Pathway-Focused PCR Array including SCN10A:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCN10A Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SCN10A | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCN10A | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCN10A | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCN10A |
Orthologs for SCN10A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SCN10A gene from 2/15 species (see all 15) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
zebrafish (Danio rerio) |
Actinopterygii |
CABZ01040037.16CABZ01063402.16(see all 3) |
-- |
61(a)52(a)(see all 3) |
many ↔ manymany ↔ many(see all 3) |
2(51470415-51506531) 24(42714922-42889682) |
fruit fly (Drosophila melanogaster) |
Insecta |
NaCP60E3 |
sodium ion transport voltage-gated sodium channel |
62(a) |
  |
60E5 -- |
ENSEMBL Gene Tree for SCN10A (if available) TreeFam Gene Tree for SCN10A (if available)  |
Paralogs for SCN10A gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SCN10A gene
- CACNA1A2 SCN5A2 SCN9A2 CACNA1D2 CACNA1I2 SCN7A2 CACNA1F2 SCN8A2
- CACNA1G2 SCN3A2 CACNA1E2 SCN2A2 CACNA1H2 CACNA1S2 CACNA1C2 SCN11A2
- SCN4A2 SCN1A2 CACNA1B2
11 SIMAP similar genes for SCN10A using alignment to 1 protein entry: SCNAA_HUMAN:SCN5A SCN3A SCN4A SCN1A SCN2A SCN9A SCN8A SCN11A SCN2A2 SCN7A CACNA1B
SCN10A for paralogs About GeneDecksing
|
Genomic Variants for SCN10A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 3 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SCN10A (38738293 - 38835501 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SCN10A: -- Human Gene Mutation Database (HGMD): SCN10A
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCN10A |
|
Disorders
/ Diseases for SCN10A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SCN10A for disorders About GeneDecksing
OMIM gene information: 604427
OMIM disorders: --
6 diseases for SCN10A: About MalaCardstrigeminal neuralgia peripheral neuropathy penis carcinoma neuropathy neuroma neuronitis 3 diseases from the University of Copenhagen DISEASES database for SCN10A:Melanoma Breast cancer Carcinoma Human Genome Epidemiology (HuGE) Navigator: SCN10A (6 documents) Export disorders for SCN10A gene to outside databases
|
Publications for SCN10A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SCN10A gene, integrated from 9 sources (see all 60): (articles sorted by number of sources associating them with SCN10A) | |  | Utopia: connect your pdf to the dynamic world of online information |
- A tetrodotoxin-resistant voltage-gated sodium channel from human dorsal root ganglia, hPN3/SCN10A. (PubMed id 9839820)1, 2, 3, 9 Rabert D.K.... Sangameswaran L. (1998)
- International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. (PubMed id 16382098)1, 3 Catterall W.A....Waxman S.G. (2005)
- Evolution and diversity of mammalian sodium channel genes. (PubMed id 10198179)1, 3 Plummer N.W. and Meisler M.H. (1999)
- Gain-of-function Nav1.8 mutations in painful neuropath y. (PubMed id 23115331)1 Faber C.G....Waxman S.G. (2012)
- Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. (PubMed id 21248752)2 Varela I....Futreal P.A. (2011)
- Localisation of SCN10A gene product Na(v)1.8 and nove l pain-related ion channels in human heart. (PubMed id 21646736)1 Facer P....Anand P. (2011)
- Transmembrane segments prevent surface expression of sodium channel Nav1.8 and promote calnexin-dependent channel degradation. (PubMed id 20720009)1 Li Q....Bao L. (2010)
- A subtle alternative splicing event of the Na(V)1.8 v oltage-gated sodium channel is conserved in human, rat, and mouse. (PubMed id 19953341)1 Schirmeyer J....Heinemann S.H. (2010)
- Genome-wide association study of PR interval. (PubMed id 20062060)1 Pfeufer A....Heckbert S.R. (2010)
- Fast- or slow-inactivated state preference of Na+ cha nnel inhibitors: a simulation and experimental study. (PubMed id 20585544)7 Karoly R....Mike A. (2010)
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External Searches for SCN10A gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SCN10A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SCN10A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SCN10A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SCN10A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SCN10A gene: Search GeneIP for patents involving SCN10A
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SCN10A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SCN10A | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SCN10A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCN10A | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SCN10A | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCN10A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCN10A | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SCN10A | | OriGene Custom Protein Services for SCN10A | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SCN10A | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCN10A | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCN10A | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SCN10A | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCN10A | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCN10A |
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 |
 | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCN10A |
|  |  |  | | | Search ThermoFisher Antibodies for SCN10A |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCN10A |
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