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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SCML2 Gene

protein-coding   GIFtS: 50
GCID: GC0XM018167

Sex Comb On Midleg-Like 2 (Drosophila)

(Previous name: sex comb on midleg (Drosophila)-like 2)
  Search for SCML2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Sex Comb On Midleg-Like 2 (Drosophila)1 2
Sex Comb On Midleg (Drosophila)-Like 21
Sex Comb On Midleg-Like Protein 22

External Ids:    HGNC: 105811   Entrez Gene: 103892   Ensembl: ENSG000001020987   OMIM: 3002085   UniProtKB: Q9UQR03   
ORGUL members:         
NONCODE14:n409355      

Export aliases for SCML2 gene to outside databases

Previous GC identifers: GC0XM017801 GC0XM016923 GC0XM017459 GC0XM017618 GC0XM018017 GC0XM016015


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SCML2 Gene:
This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes
which are involved in transcriptional repression. The encoded protein binds histone peptides that are
monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development.
(provided by RefSeq, Jun 2010)

GeneCards Summary for SCML2 Gene: 
SCML2 (sex comb on midleg-like 2 (Drosophila)) is a protein-coding gene, and is affiliated with the lncRNA class. GO annotations related to this gene include DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is L3MBTL1.

UniProtKB/Swiss-Prot: SCML2_HUMAN, Q9UQR0
Function: Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are
required to maintain the transcriptionally repressive state of homeotic genes throughout development (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_167197.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SCML2 gene promoter:
         ISGF-3   LHX3b/Lhx3b   SREBP-1c   RelA   SREBP-1b   SREBP-1a   Nkx6-1   HOXA5   LHX3a/Lhx3a   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCML2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SCML2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCML2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22   Ensembl cytogenetic band:  Xp22.13   HGNC cytogenetic band: Xp22

SCML2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCML2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM018167:  view genomic region     (about GC identifiers)

Start:
18,257,433 bp from pter      End:
18,372,847 bp from pter
Size:
115,415 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SCML2_HUMAN, Q9UQR0 (See protein sequence)
Recommended Name: Sex comb on midleg-like protein 2  
Size: 700 amino acids; 77257 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAH51913.1; Type=Erroneous initiation;
4 PDB 3D structures from and Proteopedia for SCML2:
1OI1 (3D)        2BIV (3D)        2VYT (3D)        4EDU (3D)    
Secondary accessions: Q5JXE6 Q86U98 Q8IWD0 Q8NDP2 Q9UGC5
Alternative splicing: 2 isoforms:  Q9UQR0-1   Q9UQR0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SCML2: NX_Q9UQR0

Explore proteomics data for SCML2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UQR0

  • SCML2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SCML2 Protein Expression
    REFSEQ proteins: NP_006080.1  
    ENSEMBL proteins: 
     ENSP00000407315   ENSP00000251900   ENSP00000381126  

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    Cloud-Clone Corp. Proteins for SCML2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0031519PcG protein complex IDA--

    SCML2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SAMD: Sterile alpha motif (SAM) domain containing

    5 InterPro protein domains:
     IPR004092 Mbt
     IPR013761 SAM/pointed
     IPR001660 SAM
     IPR021129 SAM_type1
     IPR021987 DUF3588

    Graphical View of Domain Structure for InterPro Entry Q9UQR0

    ProtoNet protein and cluster: Q9UQR0

    1 Blocks protein domain: IPB001660 Sterile alpha motif SAM

    UniProtKB/Swiss-Prot: SCML2_HUMAN, Q9UQR0
    Similarity: Belongs to the SCM family
    Similarity: Contains 2 MBT repeats
    Similarity: Contains 1 SAM (sterile alpha motif) domain


    SCML2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SCML2_HUMAN, Q9UQR0
    Function: Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are
    required to maintain the transcriptionally repressive state of homeotic genes throughout development (By
    similarity)

         Genatlas biochemistry entry for SCML2:
    Drosophila sex comb on midleg-like 2 homolog,member of the polycomb group (PcG),involved in transcriptional
    repression of HOX genes,clustered with SCML1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding TAS10331946
    GO:0003700sequence-specific DNA binding transcription factor activity TAS10331946
    GO:0005515protein binding ----
         
    SCML2 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidSCML2 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SCML2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/33 Interacting proteins for SCML2 (Q9UQR03 ENSP000002519004) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP7Q930093, ENSP000003435354I2D: score=2 STRING: ENSP00000343535
    ASXL1ENSP000003648394STRING: ENSP00000364839
    BMI1ENSP000003658514STRING: ENSP00000365851
    CBX2ENSP000003087504STRING: ENSP00000308750
    CBX4ENSP000002693974STRING: ENSP00000269397
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0009653anatomical structure morphogenesis TAS10331946

    SCML2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SCML2

    Search CenterWatch for drugs/clinical trials and news about SCML2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SCML2 gene: 
    NM_006089.2  

    Unigene Cluster for SCML2:

    Sex comb on midleg-like 2 (Drosophila)
    Hs.495774  [show with all ESTs]
    Unigene Representative Sequence: BC040497
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000420857 ENST00000251900(uc004cyk.3 uc004cyl.2 uc010nfd.1 uc011miz.1)
    ENST00000491988 ENST00000398048(uc010nfc.2)
    miRNA
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    hsa-miR-2052 hsa-miR-3938 hsa-miR-19b-2* hsa-miR-548k hsa-miR-106a hsa-miR-218-1* hsa-miR-29a hsa-miR-301a
    SwitchGear 3'UTR luciferase reporter plasmidSCML2 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCML2

    Additional mRNA sequence: 

    AK022824.1 AK299190.1 AK303064.1 AK308140.1 AK315116.1 AL833937.1 BC040497.1 BC051913.1 
    BC064617.1 NR_033717.1 Y18004.1 

    7 DOTS entries:

    DT.412147  DT.100747883  DT.100747879  DT.121324985  DT.100652625  DT.75127636  DT.100016848 

    24/46 AceView cDNA sequences (see all 46):

    AI879626 AL554003 BC064617 AA227119 AL711779 AA618466 AK022824 BC051913 
    AL705518 BX510293 AA223301 AI879244 H19270 AU127487 NM_006089 BU567664 
    AL833937 BU561247 BG531261 BC040497 AA223373 BI562446 BX093433 BI767606 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SCML2 (see all 9)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c · 12d ^ 13a · 13b · 13c ^ 14 ^ 15a · 15b · 15c ^ 16 ^
    SP1:                                                                                                                                                            
    SP2:                                                        -     -                                                                                             
    SP3:                                                        -     -                                                                                             
    SP4:                                                              -                                                                                             
    SP5:                                                                                                                                                            

    ExUns: 17a · 17b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for SCML2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SCML2 expression in normal human tissues (normalized intensities)      SCML2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SCML2 Expression
    About this image


    SCML2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             XY Germ Cells Testis Cord
             sperm   
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             XX Germ Cells Ovigerous Cord
             oocyte   
     
     Gonad
             XY Germ Cells Testis Cord
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             bone marrow cd34+   
     
     Peripheral Nervous System (Nervous System)
             PERIPHERAL NERVOUS SYSTEM   

    See SCML2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SCML2

    SOURCE GeneReport for Unigene cluster: Hs.495774

    UniProtKB/Swiss-Prot: SCML2_HUMAN, Q9UQR0
    Tissue specificity: Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver,
    skeletal muscle, pancreas and ovary

        SABiosciences Expression via Pathway-Focused PCR Array including SCML2: 
              Polycomb & Trithorax Complexes in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCML2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SCML2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scml21 , 5 sex comb on midleg-like 2 (Drosophila)1, 5 72.29(n)1
    62.65(a)1
      X (73.95 cM)5
    1078151  NM_133194.31  NP_573457.31 
     1611171935 
    chicken
    (Gallus gallus)
    Aves SCML21 sex comb on midleg-like 2 (Drosophila) 71.01(n)
    63.77(a)
      418613  XM_416812.3  XP_416812.3 
    lizard
    (Anolis carolinensis)
    Reptilia SCML26
    sex comb on midleg-like 2 (Drosophila)
    51(a)
    1 ↔ 1
    3(122798866-122846953)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.202962 Transcribed sequence with weak similarity to protein more 79.08(n)    BX751421.1 
    zebrafish
    (Danio rerio)
    Actinopterygii scml21 sex comb on midleg-like 2 (Drosophila) 58.43(n)
    54.32(a)
      559561  XM_003199502.1  XP_003199550.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Scm1 , 3 gene silencing specific RNA polymerase
    II transcription more3
    Sex comb on midleg1
    62(a)3
    57.27(n)1
    54.36(a)1
      3 85E23
    411681  NM_169299.11  NP_731385.11 


    ENSEMBL Gene Tree for SCML2 (if available)
    TreeFam Gene Tree for SCML2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SCML2 gene
    L3MBTL12  L3MBTL22  SCML42  L3MBTL32  SFMBT12  SCML12  L3MBTL42  SCMH12  
    SFMBT22  MBTD12  
    2 SIMAP similar genes for SCML2 using alignment to 3 protein entries:     SCML2_HUMAN (see all proteins):
    SCMH1    SCML4

    SCML2 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SCML2
    PGOHUM00000249025 PGOHUM00000234978


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1391 SNPs in SCML2 are shown (see all 1391)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1917347821,2
    --18170495(+) GGAGGC/TGGCCT 2 -- ds50010--------
    rs120083221,2
    C,H--18170496(+) GAGGCA/GGCCTC 2 -- ds50010--------
    rs1489973841,2
    --18170574(+) ATCTCA/GGGGCA 2 -- ds50010--------
    rs1841401781,2
    --18170596(+) TAGCAC/TTCTCG 2 -- ds50010--------
    rs1471124481,2
    --18170824(+) TTCCAA/TCAAAT 2 -- ds50010--------
    rs59559581,2
    C--18170935(+) CTGTAA/GAACAT 2 -- ut31 nc-transcript-variantese31Minor allele frequency- G:0.00NA 2
    rs1379596751,2
    --18170974(+) TCAAGC/TGGGTA 2 -- ut31 nc-transcript-variant0--------
    rs1419410451,2
    --18171107(+) GGTTTG/TCTAAA 2 -- ut31 nc-transcript-variant0--------
    rs169807531,2
    C,F,H--18171777(+) TTTTAC/TGAAAT 2 -- ut31 int1 ese311Minor allele frequency- T:0.01NA NS EA 940
    rs1898398521,2
    --18172188(+) TGAAAA/GCTTAT 2 -- ut31 int10--------

    HapMap Linkage Disequilibrium report for SCML2 (18257433 - 18372847 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SCML2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2663102CNV Deletion23128226
    nsv6819CNV Insertion18451855
    esv24903CNV Loss19812545


    Locus Specific Mutation Databases (LSDB): SCML2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SCML2 for disorders           About MalaCards
    OMIM gene information: 300208    OMIM disorders: --


    SCML2 for disorders           About GeneDecksing


    Export disorders for SCML2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SCML2 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with SCML2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of SCML2, a second human gene homologous to the Drosophila Sex comb on midleg (Scm): a new gene cluster on Xp22. (PubMed id 10331946)1, 2, 3 Montini E.... Franco B. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Crystal structure of the malignant brain tumor (MBT) repeats in sex comb on midleg-like 2 (SCML2). (PubMed id 12952983)1, 2 Sathyamurthy A.... Bycroft M. (2003)
    4. PCGF homologs, CBX proteins, and RYBP define functiona lly distinct PRC1 family complexes. (PubMed id 22325352)1 Gao Z....Reinberg D. (2012)
    5. A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. (PubMed id 22412018)1 Roux K.J.... Burke B. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. Purification and identification of endogenous polySUMO conjugates. (PubMed id 21252943)1 Bruderer R....Hay R.T. (2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    10. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10389 HGNC: 10581 AceView: SCML2 Ensembl:ENSG00000102098 euGenes: HUgn10389
    ECgene: SCML2 H-InvDB: SCML2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SCML2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SCML2 gene:
    Search GeneIP for patents involving SCML2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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