SCLY Gene
protein-coding GIFtS: 54
GCID: GC02P238985
|
|
selenocysteine lyase
| |
Aliases
for SCLY gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Selenocysteine Lyase1 2 | | SCL1 2 3 5 | | HSCL1 | | EC 4.4.1.163 8 |
Export aliases for SCLY gene to outside databasesPrevious GC identifers: GC02P236925 GC02P237558 GC02P239256 GC02P238751 GC02P238634 GC02P230761 |
Summaries
for SCLY gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SCLY:
Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion ofL-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 (PubMed 10692412)).(supplied by OMIM, Mar2008)
UniProtKB/Swiss-Prot: SCLY_HUMAN, Q96I15Function: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium (By similarity)
|
Genomic Views
for SCLY gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005120.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SCLY gene promoter:
AP-1 ATF-2 Lmo2 FOXD1 GATA-1 AREB6 MZF-1 c-Jun Zic3 LyF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SCLY
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCLY |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q37.3 Ensembl cytogenetic band: 2q37.3 HGNC cytogenetic band: 2q37.3SCLY Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P238985: view genomic region
(about GC identifiers)
Start:
|
238,969,530 bp from pter |
End:
|
239,008,054 bp from pter |
Size:
|
38,525 bases |
Orientation:
|
plus strand |
|
Proteins
for SCLY gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SCLY_HUMAN, Q96I15 (See
protein sequence)Recommended Name: Selenocysteine lyase Size: 445 amino acids; 48149 Da
Cofactor: Pyridoxal phosphate
Subunit: Homodimer (By similarity)
Subcellular location: Cytoplasm, cytosol (By similarity)
Sequence caution: Sequence=BAA91659.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for SCLY:3GZC (3D)
3GZD (3D)
Secondary accessions: B9A068 Q53SN1 Q53SN8 Q7L670 Q9NVT7 Q9NZR7Alternative splicing: 2 isoforms: Q96I15-1 Q96I15-2 Explore the universe of human proteins at neXtProt for SCLY: NX_Q96I15
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96I15
4/6 DME Specific Peptides for SCLY (Q96I15) (see all 6)
SCLY Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057594.4
ENSEMBL proteins: ENSP00000254663 ENSP00000414165 ENSP00000391361 ENSP00000387162 ENSP00000392517 ENSP00000416344 ENSP00000406710 ENSP00000404473 ENSP00000402078 ENSP00000404444 ENSP00000414053 ENSP00000405907 ENSP00000401401 ENSP00000450613 ENSP00000416865 ENSP00000393694 ENSP00000362429
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
IEA | -- |
SCLY for ontologies About GeneDecksing
SCLY Antibody Products:
Assay Products for SCLY: |
Protein
Domains /
Families
for SCLY gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SCLY for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96I15ProtoNet protein and cluster: Q96I15 1 Blocks protein family: IPB000192 Aminotransferase
UniProtKB/Swiss-Prot: SCLY_HUMAN, Q96I15Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family |
Function
for SCLY gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SCLY_HUMAN, Q96I15Function: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium (By similarity)Catalytic activity: L-selenocysteine + reduced acceptor = selenide + L-alanine + acceptorInduction: Up-regulated in acute glomerulonephritis. Regulated by JUN/AP-1Enzyme Number (IUBMB): EC 4.4.1.161 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCLY (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCLY
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SCLY (NM_016510) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCLY | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCLY |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCLY |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SCLY for ontologies About GeneDecksing
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Scly):
SCLY for phenotypes About GeneDecksing
|
Pathways & Interactions
for SCLY gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Selenium Metabolism and Selenoproteins | | | 2 | Selenocompound metabolism | | | 3 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SCLY
2 
Kegg Pathways (Kegg details for SCLY):
SCLY for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SCLY
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/12 Interacting proteins for SCLY (Q96I153 ENSP000002546634) via UniProtKB, MINT, STRING, and/or I2D (see all 12)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006520 | cellular amino acid metabolic process |
TAS | 10692412 |
SCLY for ontologies About GeneDecksing
|
Drugs & Compounds
for SCLY gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SCLY for compounds About GeneDecksing
 Browse Tocris compounds for SCLY
4 HMDB Compounds for SCLY About this table
1 DrugBank Compound for SCLY About this table
3 Novoseek chemical compound relationships for SCLY gene About this table
Search CenterWatch for drugs/clinical trials and news about SCLY
|
Transcripts
for SCLY gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SCLY gene: NM_016510.5 Unigene Cluster for SCLY: Selenocysteine lyase Hs.731909 [show with all ESTs]Unigene Representative Sequence: AB20945818/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24): ENST00000254663(uc010fyv.3 uc010znr.2 uc010znq.2) ENST00000480357
ENST00000497256 ENST00000413463 ENST00000446202 ENST00000409736 ENST00000423324
ENST00000412508 ENST00000443532 ENST00000416757 ENST00000487197 ENST00000480859
ENST00000482031 ENST00000431487 ENST00000437134 ENST00000497951 ENST00000450965
ENST00000440143
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCLY (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCLY
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SCLY (NM_016510) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCLY | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCLY |
Additional cDNA sequence: AB209458.2 AF175767.1 AK001377.1 AK127520.1 AK293283.1 AK298409.1 AK301009.1 BC000586.2 BC007891.2 BC018966.2 11 DOTS entries: DT.95161160 DT.206965 DT.95161164 DT.91745044 DT.70103021 DT.101960273 DT.444590 DT.100825713 DT.70102676 DT.97808648 DT.97799220 24/318 AceView cDNA sequences (see all 318): BM922883 BM793135 BU633895 AF310723 AA178940 BQ013232 CF528949 AA602645 CD107215 BM142018 CB123239 AA806862 AA179031 BC010549 CR597637 BU689854 AI669951 AI792322 AI688377 BE855458 AI082068 BP374876 AI734980 AA683518
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SCLY (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | - | | | | | | - | | | | | | | | - | | | | | | | | - | | | | | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | - | | - | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14a | · | 14b | ^ | 15a | · | 15b |
|---|
|
| SP1: | - | | | | | | | | |
| SP2: | | | | | | | | | |
| SP3: | | | | | | | | | |
| SP4: | | | | | | | | | |
| SP5: | | | | | | | | |
ECgene alternative splicing isoforms for SCLY
|
Expression
for SCLY gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SCLY expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGATTTTGA
About this image
See SCLY Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SCLY
SOURCE GeneReport for Unigene cluster: Hs.731909
SABiosciences Custom PCR Arrays for SCLY
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCLY
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SCLY | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCLY | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCLY | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCLY |
Orthologs
for SCLY gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SCLY gene from 4/19 species (see all 19) About this table
ENSEMBL Gene Tree for SCLY (if available)
TreeFam Gene Tree for SCLY (if available) |
Paralogs
for SCLY gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SCLY gene
- NFS12
1 SIMAP similar gene for SCLY using alignment to 18 protein entries: SCLY_HUMAN (see all proteins):NFS1
SCLY for paralogs About GeneDecksing
|
Genomic Variants
for SCLY gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SCLY (238969530 - 239008054 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SCLY: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCLY |
|
Disorders
/ Diseases
for SCLY gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SCLY for disorders About GeneDecksing
OMIM gene information: 611056
OMIM disorders: --
10  diseases for SCLY: About MalaCardshepatitis c lung adenocarcinoma glomerulonephritis hepatocellular carcinoma
adenocarcinoma hepatitis pneumonia tuberculosis
carcinoma mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: SCLY (1 document)
Export disorders for SCLY gene to outside databases
|
Publications
for SCLY gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SCLY gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with SCLY) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase. Candidate for selenium delivery protein in selenoprotein synthesis. (PubMed id 10692412)1, 2, 3, 9 Mihara H.... Esaki N. (2000)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Characterization of selenocysteine lyase in human tissues and its relationship to tissue selenium concentrations. (PubMed id 1483038)1, 9 Daher R. and Van Lente F. (1992)
- Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase . (PubMed id 22295093)1 Collins R....Hogbom M. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocystein e lyase. (PubMed id 22291978)1 Johansson A.L....Hogbom M. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
|
External Searches for SCLY gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SCLY gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SCLY gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SCLY gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SCLY | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SCLY gene:
Search GeneIP for patents involving SCLY
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SCLY gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SCLY | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SCLY | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCLY | | | OriGene Protein Over-expression Lysate for SCLY | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SCLY | | OriGene 3'-UTR Clone for SCLY | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCLY | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCLY | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SCLY | | OriGene Custom Protein Services for SCLY | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SCLY | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCLY | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCLY | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SCLY | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCLY | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCLY |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SCLY |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | SCLY Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCLY |
|  |  |  | | | | Search ThermoFisher Antibodies for SCLY |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCLY |
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