Aliases for SCLT1 Gene
External Ids for SCLT1 Gene
Previous GeneCards Identifiers for SCLT1 Gene
This gene encodes an adaptor protein. Studies of a related gene in rat suggest that the encoded protein functions to link clathrin to the sodium channel protein type 10 subunit alpha protein. The encoded protein has also been identified as a component of distal appendages of centrioles that is necessary for ciliogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
GeneCards Summary for SCLT1 Gene
SCLT1 (Sodium Channel And Clathrin Linker 1) is a Protein Coding gene. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance. GO annotations related to this gene include protein C-terminus binding and sodium channel regulator activity.
UniProtKB/Swiss-Prot for SCLT1 Gene
Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity).