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Aliases for SCHLAP1 Gene

Subcategory (RNA class) for SCHLAP1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for SCHLAP1 Gene

  • SWI/SNF Complex Antagonist Associated With Prostate Cancer 1 (Non-Protein Coding) 2 3 5
  • Second Chromosome Locus Associated With Prostate 1 2 3
  • Long Intergenic Non-Protein Coding RNA 913 2 3
  • Prostate Cancer Associated Transcript 11 2 3
  • LINC00913 3
  • PCAT114 3
  • PCAT11 3

External Ids for SCHLAP1 Gene

Previous HGNC Symbols for SCHLAP1 Gene

  • LINC00913

Previous GeneCards Identifiers for SCHLAP1 Gene

  • GC02U903022

Summaries for SCHLAP1 Gene

GeneCards Summary for SCHLAP1 Gene

SCHLAP1 (SWI/SNF Complex Antagonist Associated With Prostate Cancer 1 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with SCHLAP1 include Prostate Cancer 1 and Prostate Cancer.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SCHLAP1 Gene

Genomics for SCHLAP1 Gene

Regulatory Elements for SCHLAP1 Gene

Enhancers for SCHLAP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F180655 0.9 Ensembl ENCODE 0.3 -35.5 -35487 1.6 CTCF JUN CEBPB SIN3A TSHZ1 EP300 OSR2 MAFF JUND FOSL2 SCHLAP1 ENSG00000270289
GH02F180661 0.7 Ensembl ENCODE 0.3 -29.8 -29767 2.3 FOS FOSL2 SCHLAP1 ENSG00000270289
GH02F180676 0.5 ENCODE 0.4 -14.6 -14599 1.5 ZBTB33 RAD21 NR2F2 YY1 SCHLAP1 ENSG00000270289
GH02F180625 0.6 ENCODE 0.2 -66.4 -66436 0.2 JUND BHLHE40 FOS MAFK SP7 UBE2E3 SCHLAP1 ENSG00000270289
GH02F180522 0.8 Ensembl ENCODE 0.1 -168.4 -168424 3.2 JUND JUN BHLHE40 FOS ENSG00000270289 SCHLAP1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SCHLAP1 on UCSC Golden Path with GeneCards custom track

Genomic Location for SCHLAP1 Gene

Chromosome:
2
Start:
180,692,104 bp from pter
End:
180,916,939 bp from pter
Size:
224,836 bases
Orientation:
Plus strand

Genomic View for SCHLAP1 Gene

Genes around SCHLAP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCHLAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCHLAP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCHLAP1 Gene

Proteins for SCHLAP1 Gene

Post-translational modifications for SCHLAP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SCHLAP1 Gene

Domains & Families for SCHLAP1 Gene

Gene Families for SCHLAP1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SCHLAP1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SCHLAP1 Gene

Function for SCHLAP1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SCHLAP1 Gene

Localization for SCHLAP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SCHLAP1 Gene

Pathways & Interactions for SCHLAP1 Gene

SuperPathways for SCHLAP1 Gene

No Data Available

Interacting Proteins for SCHLAP1 Gene

Gene Ontology (GO) - Biological Process for SCHLAP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SCHLAP1 Gene

Transcripts for SCHLAP1 Gene

mRNA/cDNA for SCHLAP1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SCHLAP1 Gene

No ASD Table

Relevant External Links for SCHLAP1 Gene

GeneLoc Exon Structure for
SCHLAP1
ECgene alternative splicing isoforms for
SCHLAP1

Expression for SCHLAP1 Gene

NURSA nuclear receptor signaling pathways regulating expression of SCHLAP1 Gene:

SCHLAP1
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SCHLAP1 Gene

Orthologs for SCHLAP1 Gene

Evolution for SCHLAP1 Gene

ENSEMBL:
Gene Tree for SCHLAP1 (if available)
TreeFam:
Gene Tree for SCHLAP1 (if available)

No data available for Orthologs for SCHLAP1 Gene

Paralogs for SCHLAP1 Gene

No data available for Paralogs for SCHLAP1 Gene

Variants for SCHLAP1 Gene

Sequence variations from dbSNP and Humsavar for SCHLAP1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1002498 -- 180,719,999(-) CAGTT(C/G)TGTTA intron-variant, nc-transcript-variant
rs1009998 -- 180,714,586(+) GAATT(C/G)CCAAC intron-variant
rs1015227 -- 180,717,451(-) GCATA(A/T)GTAAA intron-variant
rs10153615 -- 180,846,985(+) AAATC(A/G)TGCCA intron-variant
rs10164453 -- 180,784,699(+) ttatg(G/T)gacag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SCHLAP1 Gene

Variant ID Type Subtype PubMed ID
nsv963752 CNV duplication 23825009
nsv834475 CNV gain 17160897
nsv821835 CNV gain 20364138
nsv1138870 CNV deletion 24896259
nsv1115584 CNV duplication 24896259
nsv1114151 CNV deletion 24896259
nsv1077898 CNV duplication 25765185
nsv1072053 CNV deletion 25765185
esv3893513 CNV loss 25118596
esv3364161 CNV duplication 20981092
esv1567921 CNV deletion 17803354
esv1564115 CNV insertion 17803354
esv1505605 CNV deletion 17803354
esv1004332 CNV deletion 20482838

Relevant External Links for SCHLAP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SCHLAP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SCHLAP1 Gene

Disorders for SCHLAP1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for SCHLAP1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
prostate cancer 1
  • prostate cancer, familial
prostate cancer
  • prostate cancer, hereditary, 5
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for SCHLAP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SCHLAP1
genes like me logo Genes that share disorders with SCHLAP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SCHLAP1 Gene

Publications for SCHLAP1 Gene

  1. The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex. (PMID: 24076601) Prensner J.R. … Chinnaiyan A.M. (Nat. Genet. 2013) 2 3 64
  2. Linking the SWI/SNF complex to prostate cancer. (PMID: 24165726) Lee R.S. … Roberts C.W. (Nat. Genet. 2013) 2 3 64
  3. RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1. (PMID: 25456366) Prensner J.R. … Feng F.Y. (Lancet Oncol. 2014) 3 64
  4. A novel RNA in situ hybridization assay for the long noncoding RNA SChLAP1 predicts poor clinical outcome after radical prostatectomy in clinically localized prostate cancer. (PMID: 25499224) Mehra R. … Chinnaiyan A.M. (Neoplasia 2014) 3 64

Products for SCHLAP1 Gene

Sources for SCHLAP1 Gene

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