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SCHIP1 Gene

protein-coding   GIFtS: 50
GCID: GC03P158991

Schwannomin Interacting Protein 1

(Previous name: schwannomin-interacting protein 1)
  See SCHIP1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Schwannomin Interacting Protein 11 2
Schwannomin-Interacting Protein 11 2
SCHIP-12 3
Schwannomin Interacting Protein 1 Variant 11
Schwannomin Interacting Protein 1 Variant 21

External Ids:    HGNC: 156781   Entrez Gene: 299702   Ensembl: ENSG000001519677   UniProtKB: Q9P0W53   

Export aliases for SCHIP1 gene to outside databases

Previous GC identifers: GC03P156276 GC03P159938 GC03P160272 GC03P160312 GC03P160474 GC03P156388


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SCHIP1 Gene:
SCHIP1 (schwannomin interacting protein 1) is a protein-coding gene. Diseases associated with SCHIP1 include papillary renal cell carcinoma. GO annotations related to this gene include identical protein binding. An important paralog of this gene is IQCJ-SCHIP1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the SCHIP1 gene promoter:
         AML1a   NRSF form 1   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   POU6F1 (c2)   POU3F2   HNF-3beta   NRSF form 2   ARP-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCHIP1 promoter sequence
   Search Chromatin IP Primers for SCHIP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCHIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.32-q25.33   Ensembl cytogenetic band:  3q25.33   HGNC cytogenetic band: 3q25.32-q25.33

SCHIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCHIP1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P158991:  view genomic region     (about GC identifiers)

Start:
158,991,036 bp from pter      End:
159,615,155 bp from pter
Size:
624,120 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SCHI1_HUMAN, Q9P0W5 (See protein sequence)
Recommended Name: Schwannomin-interacting protein 1  
Size: 487 amino acids; 53480 Da
Subunit: Isoform 5 interacts (via C-terminal IQ motif) with calmodulin in the absence of Ca(2+) (By similarity).
Isoform 5 interacts (via C-terminus) with ANK3 (via N-terminal ANK repeats); this interaction is required for the
localization at axon initial segments (AISs) and nodes of Ranvier (NRs) (By similarity). Self-associates through
its coiled coil domain. Interacts with NF2 isoform 4, but not NF2 isoform 1. Interacts with NF2 variant PHE-119
DEL
Secondary accessions: B3KRM0 O75543 Q00P30 Q00P31 Q7Z3Y3 Q8IY83 Q9P0W3 Q9P0W4
Alternative splicing: 6 isoforms:  Q9P0W5-1   Q9P0W5-2   Q9P0W5-3   Q9P0W5-4   Q9P0W5-5   Q9P0W5-6   (Based on a naturally occurring readthrough transcript which produces an IQCJ-SCHIP1 fusion protein)

Explore the universe of human proteins at neXtProt for SCHIP1: NX_Q9P0W5

Explore proteomics data for SCHIP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SCHIP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001184036.1  NP_001184037.1  NP_001184038.1  NP_055390.1  

    ENSEMBL proteins: 
     ENSP00000404860   ENSP00000420376   ENSP00000419230  

    SCHIP1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SCHIP1

     
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    antibodies-online proteins for SCHIP1 (3 products) 

     
    antibodies-online peptides for SCHIP1

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    antibodies-online antibodies for SCHIP1 (29 products) 

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    Cloud-Clone Corp. CLIAs for SCHIP1
    Search eBioscience for ELISAs for SCHIP1 
    antibodies-online kits for SCHIP1 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR015649 SCHIP_1

    Graphical View of Domain Structure for InterPro Entry Q9P0W5

    ProtoNet protein and cluster: Q9P0W5


    Find genes that share domains with SCHIP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0042802identical protein binding IPI10669747
         
    Find genes that share ontologies with SCHIP1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SCHIP1:
     Decreased circadian period len 

         11 MGI mutant phenotypes (inferred from 1 allele(MGI details for Schip1):
     cardiovascular system  cellular  craniofacial  digestive/alimentary  endocrine/exocrine gland 
     homeostasis/metabolism  mortality/aging  muscle  renal/urinary system  reproductive system 
     skeleton 

    Find genes that share phenotypes with SCHIP1           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for SCHIP1

    miRNA
    Products:
        
    miRTarBase miRNAs that target SCHIP1:
    hsa-mir-98-5p (MIRT027531)

    Block miRNA regulation of human, mouse, rat SCHIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SCHIP1 (see all 38):
    hsa-miR-429 hsa-miR-29a hsa-miR-139-5p hsa-miR-200a hsa-miR-3653 hsa-miR-141 hsa-miR-3658 hsa-miR-1183
    SwitchGear 3'UTR luciferase reporter plasmidSCHIP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SCHIP1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCHIP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SCHI1_HUMAN, Q9P0W5: Cytoplasm. Note=Partially colocalizes with NF2 beneath the cytoplasmic membrane
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with SCHIP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SCHIP1
    Interactions:

        GeneGlobe Interaction Network for SCHIP1

    Selected Interacting proteins for SCHIP1 (Q9P0W51, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 51)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PSMD4P550361, 3EBI-1397509,EBI-359318 I2D: score=1 
    SCOCQ9UIL11, 3EBI-1397509,EBI-2686537 I2D: score=1 
    ZC3H13Q5T2001, 3EBI-1397509,EBI-2679720 I2D: score=1 
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    Find genes that share ontologies with SCHIP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SCHIP1 (SCHI1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SCHIP1 gene (4 alternative transcripts): 
    NM_001197107.1  NM_001197108.1  NM_001197109.1  NM_014575.3  

    Unigene Cluster for SCHIP1:

    Schwannomin interacting protein 1
    Hs.134665  [show with all ESTs]
    Unigene Representative Sequence: NM_014575
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000445224(uc003fcu.2) ENST00000461058 ENST00000495954 ENST00000483730
    ENST00000472483 ENST00000482804 ENST00000482885(uc010hvz.1) ENST00000475932

    miRNA
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    Block miRNA regulation of human, mouse, rat SCHIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SCHIP1 (see all 38):
    hsa-miR-429 hsa-miR-29a hsa-miR-139-5p hsa-miR-200a hsa-miR-3653 hsa-miR-141 hsa-miR-3658 hsa-miR-1183
    SwitchGear 3'UTR luciferase reporter plasmidSCHIP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SCHIP1
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    OriGene ORF clones in mouse, rat for SCHIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): SCHIP1 (NM_014575)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCHIP1
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCHIP1
      QuantiTect SYBR Green Assays in human, mouse, rat SCHIP1
      QuantiFast Probe-based Assays in human, mouse, rat SCHIP1

    Additional mRNA sequence: 

    AF070614.1 AF145713.1 AF145714.1 AF145715.1 AK091871.1 AK309223.1 AK314662.1 BC005947.1 
    BC036535.2 

    18 DOTS entries:

    DT.446547  DT.91731259  DT.100639641  DT.40131982  DT.91731260  DT.91658132  DT.91731242  DT.91731264 
    DT.101965956  DT.120918446  DT.120918575  DT.97841856  DT.100809689  DT.100832999  DT.120918508  DT.120918552 
    DT.92410187  DT.120918435 

    Selected AceView cDNA sequences (see all 165):

    BC005947 CR607011 AA573339 AI168362 AI921149 AA127646 CA431197 BF447572 
    AL534769 CB054067 AA127711 CR593613 BQ269676 BX280671 AA708955 Z40587 
    AF070614 CF132264 AW298144 BX377809 AA884869 AA719650 AK091871 AW149406 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SCHIP1 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
    SP1:        -     -     -     -     -     -                                             
    SP2:              -     -     -     -     -                                             
    SP3:                    -     -     -     -                                             
    SP4:                                -     -                                             
    SP5:                                                                                    


    ECgene alternative splicing isoforms for SCHIP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SCHIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTGCCTCGT
    SCHIP1 Expression
    About this image


    SCHIP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Kidney (Urinary System)
             Metanephros
     
     Eye (Sensory Organs)
             Retina
     
     Neural Tube (Nervous System)
             Telencephalon
    SCHIP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SCHIP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.134665

    UniProtKB/Swiss-Prot: SCHI1_HUMAN, Q9P0W5
    Tissue specificity: Isoform 5 and isoform 6 are highly expressed in the brain. Both isoforms derive from naturally
    occurring readthrough transcripts which produce IQCJ-SCHIP1 fusion proteins

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SCHIP1 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Schip11 , 5 schwannomin interacting protein 11, 5 88.79(n)1
    91.06(a)1
      3 (31.44 cM)5
    309531  NM_001113421.11  NP_001106892.11 
     680648025 
    chicken
    (Gallus gallus)
    Aves SCHIP16
    schwannomin interacting protein 1
    56(a)
    1 ↔ 1
    9(21734161-21771452)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.139872 Xenopus laevis transcribed sequence with strong similarity more 81.95(n)    CD255492.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.140612 Transcribed sequence with moderate similarity to protein more 78.2(n)    CF265466.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG53756
    --
    9(a)
    1 → many
    2L(10328200-10331116)


    ENSEMBL Gene Tree for SCHIP1 (if available)
    TreeFam Gene Tree for SCHIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SCHIP1 gene
    IQCJ-SCHIP12  
    1 SIMAP similar gene for SCHIP1 using alignment to 3 protein entries:     SCHI1_HUMAN (see all proteins):
    IQCJ-SCHIP1

    Find genes that share paralogs with SCHIP1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    2 SNPs for SCHIP1    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs178500211,2,4
    ----see VAR_0325342 mis40--------
    rs37328511,2,4
    ----see VAR_0513322 mis40--------

    HapMap Linkage Disequilibrium report for SCHIP1 (158991036 - 159241036 bp, first 250kb of SCHIP1)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SCHIP1 (see all 43):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2674821CNV Deletion23128226
    esv2669077CNV Deletion23128226
    esv2678454CNV Deletion23128226
    esv2560522CNV Deletion19546169
    esv2644833CNV Deletion19546169
    esv993836CNV Deletion20482838
    esv1917039CNV Deletion18987734
    esv2726108CNV Deletion23290073
    esv2657975CNV Deletion23128226
    esv2138340CNV Deletion18987734

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for SCHIP1:    
    About MalaCards
    papillary renal cell carcinoma

    1 disease from the University of Copenhagen DISEASES database for SCHIP1:
    Papillary renal cell carcinoma

    Find genes that share disorders with SCHIP1           About GenesLikeMe

    Genetic Association Database (GAD): SCHIP1
    Human Genome Epidemiology (HuGE) Navigator: SCHIP1 (4 documents)

    Export disorders for SCHIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SCHIP1 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with SCHIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins. (PubMed id 10669747)1, 2, 3, 9 Goutebroze L.... Thomas G. (Mol. Cell. Biol. 2000)
    2. IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein. (PubMed id 17045569)1, 2, 3, 9 Kwasnicka-Crawford D.A.... Scherer S.W. (Biochem. Biophys. Res. Commun. 2006)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. (PubMed id 19197348)1, 4 Lowe J.K....Friedman J.M. (PLoS Genet. 2009)
    6. Newly identified genetic risk variants for celiac disease related to the immune response. (PubMed id 18311140)1, 4 Hunt K.A.... van Heel D.A. (Nat. Genet. 2008)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)
    9. Assignment of the schwannomin-interacting protein 1 (SCHIP1) gene to human chromosome band 3q25 by in situ hybridization and with somatic cell hybrids. (PubMed id 11701967)1, 9 Goutebroze L....Thomas G. (Cytogenet. Cell Genet. 2001)
    10. Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. (PubMed id 23377640)1 (Am J Psychiatry 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29970 HGNC: 15678 AceView: SCHIP1.2 Ensembl:ENSG00000151967 euGenes: HUgn29970
    ECgene: SCHIP1 H-InvDB: SCHIP1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SCHIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SCHIP1 gene:
    Search GeneIP for patents involving SCHIP1

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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