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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SCHIP1 Gene

protein-coding GIFtS: 49
GCID: GC03P158991

schwannomin interacting protein 1

(Previous name: schwannomin-interacting protein 1 )

Explore 6 diseases affiliated with
SCHIP1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Schwannomin Interacting Protein 1¹ ²
SCHIP-1¹ ² ³
Schwannomin-Interacting Protein 1¹ ²

External Ids:	HGNC: 15678¹	Entrez Gene: 29970²	Ensembl: ENSG00000151967⁷	UniProtKB: Q9P0W5³

Export aliases for SCHIP1 gene to outside databases

Previous GC identifers: GC03P156276 GC03P159938 GC03P160272 GC03P160312 GC03P160474 GC03P156388

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_005612.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SCHIP1 gene promoter:
AML1a NRSF form 1 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU6F1 (c2) POU3F2 HNF-3beta NRSF form 2 ARP-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SCHIP1 promoter sequence

Search SABiosciences Chromatin IP Primers for SCHIP1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCHIP1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.32-q25.33 Ensembl cytogenetic band: 3q25.33 HGNC chromosome: 3

SCHIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCHIP1 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P158991: view genomic region (about GC identifiers)

Start:	158,991,544 bp from pter	End:	159,615,149 bp from pter
Size:	623,606 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SCHI1_HUMAN, Q9P0W5 (See protein sequence)

Recommended Name: Schwannomin-interacting protein 1

Size: 487 amino acids; 53480 Da

Subunit: Isoform 5 interacts (via C-terminal IQ motif) with calmodulin in the absence of Ca(2+) (By similarity).

Isoform 5 interacts (via C-terminus) with ANK3 (via N-terminal ANK repeats); this interaction is required for the

localization at axon initial segments (AISs) and nodes of Ranvier (NRs) (By similarity). Self-associates through its

coiled coil domain. Interacts with NF2 isoform 4, but not NF2 isoform 1. Interacts with NF2 variant PHE-119 DEL

Subcellular location: Cytoplasm. Note=Partially colocalizes with NF2 beneath the cytoplasmic membrane

Secondary accessions: B3KRM0 O75543 Q00P30 Q00P31 Q7Z3Y3 Q8IY83 Q9P0W3 Q9P0W4

Alternative splicing: 6 isoforms: Q9P0W5-1 Q9P0W5-2 Q9P0W5-3 Q9P0W5-4 Q9P0W5-5 Q9P0W5-6 (Based on a naturally occurring readthrough transcript which produces an IQCJ-SCHIP1 fusion protein)

Explore the universe of human proteins at neXtProt for SCHIP1: NX_Q9P0W5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9P0W5

SCHIP1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (4 alternative transcripts):

NP_001184036.1 NP_001184037.1 NP_001184038.1 NP_055390.1

ENSEMBL proteins:

ENSP00000404860 ENSP00000420376 ENSP00000419230

Human Recombinant Protein Products:

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	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: SCHIP1 OriGene Protein Over-expression Lysate: SCHIP1 OriGene Custom Protein Services for SCHIP1
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	Novus Biologicals SCHIP1 Protein Novus Biologicals SCHIP1 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SCHIP1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IDA	--

SCHIP1 for ontologies About GeneDecksing

SCHIP1 Antibody Products:

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	Uscn Antibodies for SCHIP1
	Search ThermoFisher Antibodies for SCHIP1

Assay Products for SCHIP1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for SCHIP1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SCHIP1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SCHIP1 for domains About GeneDecksing

1 InterPro domain/family:

IPR015649 SCHIP_1

Graphical View of Domain Structure for InterPro Entry Q9P0W5

ProtoNet protein and cluster: Q9P0W5

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone: SCHIP1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SCHIP1
		8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate SCHIP1 (see all 38):
		hsa-miR-429 hsa-miR-29a hsa-miR-139-5p hsa-miR-200a hsa-miR-3653 hsa-miR-141 hsa-miR-3658 hsa-miR-1183

		SwitchGear 3'UTR luciferase reporter plasmid: SCHIP1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SCHIP1 (see all 7) OriGene shRNA RFP: SCHIP1 OriGene siRNA: SCHIP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SCHIP1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SCHIP1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCHIP1 (see all 9) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCHIP1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 4): SCHIP1 (NM_014575)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCHIP1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCHIP1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SCHIP1
		Search LifeMap BioReagents cell lines for SCHIP1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCHIP1

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	--
GO:0042802	identical protein binding	IPI	--

SCHIP1 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for SCHIP1:

Decreased circadian period len

Animal Models:
11 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Schip1):

cardiovascular system	cellular	craniofacial	digestive/alimentary	endocrine/exocrine gland
homeostasis/metabolism	mortality/aging	muscle	renal/urinary system	reproductive system
skeleton

SCHIP1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for SCHIP1

5/51 Interacting proteins for SCHIP1 (Q9P0W5^{1, 3}) via UniProtKB, MINT, STRING, and/or I2D (see all 51)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PSMD4	P55036¹^,³	EBI-1397509,EBI-359318 I2D: score=1
SCOC	Q9UIL1¹^,³	EBI-1397509,EBI-2812448 I2D: score=1
ZC3H13	Q5T200¹^,³	EBI-1397509,EBI-2679720 I2D: score=1
CALM1	P62158³	I2D: score=1
CALM2	P62158³	I2D: score=1

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

SCHIP1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SCHIP1
Search CenterWatch for drugs/clinical trials and news about SCHIP1 / SCHI1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SCHIP1 gene (4 alternative transcripts):

NM_001197107.1 NM_001197108.1 NM_001197109.1 NM_014575.3

Unigene Cluster for SCHIP1:

Schwannomin interacting protein 1

Hs.134665 [show with all ESTs]

Unigene Representative Sequence: NM_014575

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000445224(uc003fcu.2) ENST00000461058 ENST00000495954 ENST00000483730

ENST00000472483 ENST00000482804 ENST00000482885(uc010hvz.1) ENST00000475932

miRNA Products:		OriGene 3'-UTR Clone: SCHIP1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SCHIP1
		8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate SCHIP1 (see all 38):
		hsa-miR-429 hsa-miR-29a hsa-miR-139-5p hsa-miR-200a hsa-miR-3653 hsa-miR-141 hsa-miR-3658 hsa-miR-1183

		SwitchGear 3'UTR luciferase reporter plasmid: SCHIP1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SCHIP1 (see all 7) OriGene shRNA RFP: SCHIP1 OriGene siRNA: SCHIP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SCHIP1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCHIP1 (see all 9) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCHIP1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 4): SCHIP1 (NM_014575)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCHIP1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCHIP1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCHIP1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCHIP1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCHIP1

Additional cDNA sequence:

AF070614.1 AF145713.1 AF145714.1 AF145715.1 AK091871.1 AK309223.1 AK314662.1 BC005947.1

BC036535.2

18 DOTS entries:

DT.446547 DT.91731259 DT.100639641 DT.40131982 DT.91731260 DT.91658132 DT.91731242 DT.91731264

DT.101965956 DT.120918446 DT.120918575 DT.97841856 DT.100809689 DT.100832999 DT.120918508 DT.120918552

DT.92410187 DT.120918435

24/165 AceView cDNA sequences (see all 165):

AF070614 AI373317 CR607434 BX280671 AI921149 BF447572 AA127711 AW149406

CB054067 BG060095 AA679978 AA719650 BM550652 BQ269676 Z40587 CR607011

BC005947 BX377809 Z42065 AV732055 AA884869 BM904800 CF132264 CA431197

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SCHIP1 (see all 6) About this scheme

ExUns:	1	^	2a	·	2b	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11a	·	11b
SP1:			-		-		-		-		-		-
SP2:					-		-		-		-		-
SP3:							-		-		-		-
SP4:											-		-
SP5:

ECgene alternative splicing isoforms for SCHIP1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SCHIP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTGCCTCGT

About this image

SCHIP1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

4 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Eye

Kidney

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Intervertebral disc (IVD) annulus fibrosus (AF) cells (Differentiation of s...)

Cartilage

See SCHIP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SCHIP1

SOURCE GeneReport for Unigene cluster: Hs.134665

UniProtKB/Swiss-Prot: SCHI1_HUMAN, Q9P0W5

Tissue specificity: Isoform 5 and isoform 6 are highly expressed in the brain. Both isoforms derive from naturally

occurring readthrough transcripts which produce IQCJ-SCHIP1 fusion proteins

SABiosciences Custom PCR Arrays for SCHIP1

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCHIP1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCHIP1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SCHIP1 gene from 6/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Schip1^{1 , 5}	schwannomin interacting protein 1^{1, 5}	90.06(n)¹ 92.96(a)¹		3 (31.44 cM)⁵ 30953¹ NM_001113421.1¹ NP_001106892.1¹ 68064942⁵
chicken (Gallus gallus)	Aves	IQCJ-SCHIP1⁶	Uncharacterized protein	89(a)	1 → many	9(23823965-23834346)
lizard (Anolis carolinensis)	Reptilia	IQCJ-SCHIP1⁶	--	99(a)	1 → many	3(13340230-13351450)
African clawed frog (Xenopus laevis)	Amphibia	Xl.13987²	Xenopus laevis transcribed sequence with strong similarity more	81.95(n)		CD255492.1
zebrafish (Danio rerio)	Actinopterygii	Dr.14061²	Transcribed sequence with moderate similarity to protein more	78.2(n)		CF265466.1
fruit fly (Drosophila melanogaster)	Insecta	CG5375⁶	--	9(a)	1 → many	2L(10328200-10331116)

ENSEMBL Gene Tree for SCHIP1 (if available)
TreeFam Gene Tree for SCHIP1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SCHIP1 gene

IQCJ-SCHIP1²

1 SIMAP similar gene for SCHIP1 using alignment to 3 protein entries: SCHI1_HUMAN (see all proteins):

IQCJ-SCHIP1

SCHIP1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs189702367^1,2		--	158989083(+)	`CTTCAA/GGAAGC`	5	--	int¹ us2k¹		0	--	--	--	--
rs183392563^1,2		--	158989104(+)	`CTTTTA/TAAAAA`	5	--	int¹ us2k¹		0	--	--	--	--
rs145738317^1,2		--	158989224(+)	`TTTTTA/GTAAAA`	5	--	int¹ us2k¹		0	--	--	--	--
rs9848831^1,2	C,F,A,H,	--	158989232(+)	`AAAATG/CCATAT`	5	--	us2k¹ int¹ tfbs³		7		EA NS NA WA	542
rs148954449^1,2		--	158989310(+)	`TTTATA/TTTTTT`	5	--	int¹ us2k¹		0	--	--	--	--
rs9848732^1,2	C,	--	158989332(+)	`tcactC/Gtgttg`	5	--	us2k¹ int¹		0	--	--	--	--
rs186286896^1,2		--	158989415(+)	`GCCTCA/GGCCTT`	5	--	int¹ us2k¹		0	--	--	--	--
rs192066261^1,2		--	158989453(+)	`CTACAC/TGCCTG`	5	--	int¹ us2k¹		0	--	--	--	--
rs138200507^1,2		--	158989478(+)	`TTTTAA/GTGGAG`	5	--	us2k¹ int¹		0	--	--	--	--
rs140436191^1,2		--	158989541(+)	`CCACCC/TGCCTT`	5	--	int¹ us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SCHIP1 (158991544 - 159241544 bp, first 250kb of SCHIP1)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 13 variations for SCHIP1
5 CNVs: 98504 10016 63632 98505 91668
8 Indels: 46317 46318 59103 27196 63631 43160 63023 63633

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCHIP1

DNA2.0 Custom Variant and Variant Library Synthesis for SCHIP1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SCHIP1 for disorders About GeneDecksing

6 diseases for SCHIP1: About MalaCards

pediatric ependymoma papillary renal cell carcinoma renal cell carcinoma ependymoma

celiac disease carcinoma

1 disease from the University of Copenhagen DISEASES database for SCHIP1:

Papillary renal cell carcinoma

Human Genome Epidemiology (HuGE) Navigator: SCHIP1 (4 documents)

Export disorders for SCHIP1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SCHIP1 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with SCHIP1)

Utopia: connect your pdf to the dynamic
world of online information

Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins. (PubMed id 10669747)^{1, 2, 3, 9} Goutebroze L.... Thomas G. (2000)
IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein. (PubMed id 17045569)^{1, 2, 3, 9} Kwasnicka-Crawford D.A....Scherer S.W. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)^{1, 3} Andersson B.... Gibbs R.A. (1996)
Assignment of the schwannomin-interacting protein 1 (SCHIP1) gene to human chromosome band 3q25 by in situ hybridization and with somatic cell hybrids. (PubMed id 11701967)^{1, 9} Goutebroze L....Thomas G. (2001)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Multiple common variants for celiac disease influenci ng immune gene expression. (PubMed id 20190752)¹ Dubois P.C....van Heel D.A. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
Genome-wide association studies in an isolated founde r population from the Pacific Island of Kosrae. (PubMed id 19197348)¹ Lowe J.K....Friedman J.M. (2009)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 29970	HGNC: 15678	AceView: SCHIP1.2	Ensembl:ENSG00000151967	euGenes: HUgn29970
ECgene: SCHIP1	H-InvDB: SCHIP1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for SCHIP1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SCHIP1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SCHIP1 gene:
Search GeneIP for patents involving SCHIP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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SCHIP1 Gene

schwannomin interacting protein 1

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SCHIP1 Gene

schwannomin interacting protein 1

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