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SCGN Gene

protein-coding   GIFtS: 57
GCID: GC06P025652

Secretagogin, EF-Hand Calcium Binding Protein

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Secretagogin, EF-Hand Calcium Binding Protein1 2     DJ501N12.82
SECRET2 3     SEGN2
calbindin-like1     secretagogin2
CALBL2     setagin2

External Ids:    HGNC: 169411   Entrez Gene: 105902   Ensembl: ENSG000000796897   OMIM: 6092025   UniProtKB: O760383   

Export aliases for SCGN gene to outside databases

Previous GC identifers: GC06P025709 GC06P025760


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SCGN Gene:
The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to
calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell
proliferation. (provided by RefSeq, Jul 2008)

GeneCards Summary for SCGN Gene:
SCGN (secretagogin, EF-hand calcium binding protein) is a protein-coding gene. Diseases associated with SCGN include fibrillary astrocytoma, and non-functioning pituitary adenoma. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CALB2.

Gene Wiki entry for SCGN Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the SCGN gene promoter:
         Tal-1   NRSF form 1   NRSF form 2   FOXO3b   HNF-1A   E47   S8   HNF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCGN promoter sequence
   Search Chromatin IP Primers for SCGN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCGN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.3-p22.1   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p22.3-p22.1

SCGN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCGN gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P025652:  view genomic region     (about GC identifiers)

Start:
25,652,429 bp from pter      End:
25,702,011 bp from pter
Size:
49,583 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SEGN_HUMAN, O76038 (See protein sequence)
Recommended Name: Secretagogin  
Size: 276 amino acids; 32040 Da
Secondary accessions: A8K0B2 Q5VV44 Q96QV7 Q9UJF6

Explore the universe of human proteins at neXtProt for SCGN: NX_O76038

Explore proteomics data for SCGN at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SCGN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_008929.2  
    ENSEMBL proteins: 
     ENSP00000367197   ENSP00000333933  

    SCGN Human Recombinant Protein Products:

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    SCGN Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SCGN
    Cloud-Clone Corp. CLIAs for SCGN


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    EFHAND: EF-hand domain containing

    3 InterPro protein domains:
     IPR011992 EF-hand-dom_pair
     IPR002048 EF_hand_dom
     IPR018247 EF_Hand_1_Ca_BS

    Graphical View of Domain Structure for InterPro Entry O76038

    ProtoNet protein and cluster: O76038

    UniProtKB/Swiss-Prot: SEGN_HUMAN, O76038
    Similarity: Contains 6 EF-hand domains


    SCGN for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding NAS10811645
         
    SCGN for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SCGN:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SCGN
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SCGN
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SCGN

    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate SCGN:
    hsa-miR-634 hsa-miR-924 hsa-miR-3692
    SwitchGear 3'UTR luciferase reporter plasmidSCGN 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SCGN

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    Clone
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    GenScript: all cDNA clones in your preferred vector: SCGN (NM_006998)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGN

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCGN


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SEGN_HUMAN, O76038: Cytoplasm. Secreted (By similarity). Cytoplasmic vesicle, secretory vesicle membrane;
    Peripheral membrane protein; Cytoplasmic side (By similarity). Note=Predominantly cytoplasmic. A small proportion
    is associated with secretory granules and membrane fractions (By similarity). Detectable in human serum after
    ischemic neuronal damage
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    extracellular2
    nucleus2
    mitochondrion1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005737cytoplasm NAS10811645
    GO:0030658transport vesicle membrane IEA--

    SCGN for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SCGN
    Interactions:

        Search GeneGlobe Interaction Network for SCGN

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    Selected Interacting proteins for SCGN (O760383 ENSP000003671974) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SNAP23O001613, ENSP000002496474I2D: score=4 STRING: ENSP00000249647
    PDCD6IPENSP000003073874STRING: ENSP00000307387
    GLI2ENSP000003545864STRING: ENSP00000354586
    INADLENSP000003602004STRING: ENSP00000360200
    MPDZENSP000003704104STRING: ENSP00000370410
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    SCGN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SCGN (SEGN)

    1 Novoseek inferred chemical compound relationship for SCGN gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 22.8 13 19241471 (3), 10811645 (2), 17116382 (2), 17504298 (2) (see all 6)



    SCGN for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SCGN gene: 
    NM_006998.3  

    Unigene Cluster for SCGN:

    Secretagogin, EF-hand calcium binding protein
    Hs.116428  [show with all ESTs]
    Unigene Representative Sequence: NM_006998
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377961(uc003nfb.3 uc010jpz.3) ENST00000334979

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SCGN using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate SCGN:
    hsa-miR-634 hsa-miR-924 hsa-miR-3692
    SwitchGear 3'UTR luciferase reporter plasmidSCGN 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SCGN
    Predesigned siRNA for gene silencing in human, mouse, rat SCGN
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      QuantiTect SYBR Green Assays in human, mouse, rat SCGN
      QuantiFast Probe-based Assays in human, mouse, rat SCGN

    Additional mRNA sequence: 

    AF420280.1 AK289477.1 BC000336.2 BC003036.1 Y16752.1 

    4 DOTS entries:

    DT.109196  DT.97842783  DT.99930258  DT.75106970 

    Selected AceView cDNA sequences (see all 91):

    BX090600 AK129901 BM875339 BM272713 BU789623 BQ128349 BE670017 BI916726 
    BM272961 AA327046 AI918085 BC003036 AI681029 BC000336 BE551132 BQ549417 
    AI813989 BI914714 BE674153 BQ581263 BI603234 CA776306 BI603604 AA644563 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SCGN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAATCCTGT
    SCGN Expression
    About this image


    SCGN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Pancreas (Endocrine System)    fully expand to see all 3 entries
             Endocrine Progenitor Cells Ventral Pancreatic Bud
             Islets of Langerhans
     
     Neurons
             Mature Rod Bipolar Cells Inner Nuclear Layer
     
     Neural Tube (Nervous System)
             Telencephalon
     
     Eye (Sensory Organs)
             Mature Rod Bipolar Cells Inner Nuclear Layer
     
     Brain (Nervous System)
             Cerebellum
    SCGN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SCGN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.116428

    UniProtKB/Swiss-Prot: SEGN_HUMAN, O76038
    Tissue specificity: Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in
    the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid
    C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in
    the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland,
    in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCGN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SCGN gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scgn1 , 5 secretagogin, EF-hand calcium binding protein1, 5 82.97(n)1
    84.78(a)1
      13 (10.01 cM)5
    2141891  NM_145399.11  NP_663374.11 
     239534565 
    chicken
    (Gallus gallus)
    Aves SCGN1 secretagogin, EF-hand calcium binding protein 75.56(n)
    76.32(a)
      421001  XM_419087.4  XP_419087.2 
    lizard
    (Anolis carolinensis)
    Reptilia SCGN6
    secretagogin, EF-hand calcium binding protein
    74(a)
    1 ↔ 1
    4(53417689-53452613)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia scgn1 secretagogin, EF-hand calcium binding protein 72.96(n)
    75.47(a)
      780242  NM_001079314.1  NP_001072782.1 
    zebrafish
    (Danio rerio)
    Actinopterygii scgn1 secretagogin, EF-hand calcium binding protein 70.96(n)
    74.26(a)
      573010  NM_001005776.1  NP_001005776.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Cbp53E1 , 3 calcium ion homeostasis calcium ion
    binding3
    Calbindin 53E1
    45(a)3
    53.04(n)1
    47.21(a)1
      53E43
    369051  NM_057490.31  NP_476838.11 


    ENSEMBL Gene Tree for SCGN (if available)
    TreeFam Gene Tree for SCGN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SCGN gene
    CALB22  CALB12  
    2 SIMAP similar genes for SCGN using alignment to 2 protein entries:     SEGN_HUMAN (see all proteins):
    CALB2    CALB1

    SCGN for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SCGN (see all 1096)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1409311011,2
    --25650532(+) ATCATG/TTATTT 1 -- us2k10--------
    rs1855022991,2
    --25650786(+) TTAATC/TGGTGA 1 -- us2k10--------
    rs119699811,2
    C,F,H--25650817(+) TAGGCT/AAAGCC 1 -- us2k110Minor allele frequency- A:0.12NS EA NA 1074
    rs1431628891,2
    --25650821(+) CTAAGA/CCACAC 1 -- us2k10--------
    rs718084921,2
    C--25650866(+) CCAAATATG/-  
            
    TATGT
    1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs2001979831,2
    C--25650869(-) ACATAC/TATATT 1 -- us2k10--------
    rs1997943611,2
    --25650872(+) ATGTA-/TGTATGTA 1 -- us2k10--------
    rs1898628481,2
    --25650882(+) GTATGG/TAAGAT 1 -- us2k10--------
    rs1508767711,2
    --25650987(+) CACGGA/GGTAAA 1 -- us2k10--------
    rs1160636511,2
    F--25651128(+) TCATTA/CTTATT 1 -- us2k11Minor allele frequency- C:0.03WA 118

    HapMap Linkage Disequilibrium report for SCGN (25652429 - 25702011 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SCGN:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv883488CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SCGN
    DNA2.0 Custom Variant and Variant Library Synthesis for SCGN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609202    OMIM disorders: --

    Selected diseases for SCGN (see all 21):    
    About MalaCards
    fibrillary astrocytoma    non-functioning pituitary adenoma    functioning pituitary adenoma    pituitary adenoma
    insulinoma    traumatic brain injury    neuroendocrine tumor    brain injury
    adenoma    astrocytoma    clear cell renal cell carcinoma    colorectal cancer
    cerebritis    renal cell carcinoma    alzheimer's disease    thyroiditis
    pancreatitis    adenocarcinoma    neuronitis    malaria


    SCGN for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    7 Novoseek inferred disease relationships for SCGN gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pituitary adenoma 57.5 10 15237930 (4), 17504298 (2), 14528906 (1)
    neuroendocrine tumors 56.8 5 16955307 (2), 16449819 (2), 17493385 (1)
    insulinoma 56.4 2 20061514 (1), 16888402 (1)
    carcinoid 47.2 7 16449819 (4), 16955307 (1), 17285592 (1)
    colorectal cancer 30.3 5 16586428 (3), 16955307 (1)
    adenocarcinoma 4.71 3 16449819 (2), 17285592 (1)
    tumors 0 5 16955307 (1), 16449819 (1), 17493385 (1)

    Genetic Association Database (GAD): SCGN

    Export disorders for SCGN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SCGN gene, integrated from 10 sources (see all 38):
    (articles sorted by number of sources associating them with SCGN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and expression of secretagogin, a novel neuroendocrine- and pancreatic islet of Langerhans-specific Ca2+-binding protein. (PubMed id 10811645)1, 2, 3, 9 Wagner L.... Pasternack M.S. (J. Biol. Chem. 2000)
    2. Cerebral expression and serum detectability of secretagogin, a recently cloned EF-hand Ca(2+)-binding protein. (PubMed id 11709487)1, 2, 9 Gartner W....Wagner L. (Cereb. Cortex 2001)
    3. Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. (PubMed id 19084217)1, 4 Benyamin B....Visscher P.M. (Am. J. Hum. Genet. 2009)
    4. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. (PubMed id 19503597)1, 4 Kolz M....Gieger C. (PLoS Genet. 2009)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    8. Setagin and secretagogin-R22: Posttranscriptional modification products of the secretagogin gene. (PubMed id 15766553)1, 9 Zierhut B....Wagner L. (Biochem. Biophys. Res. Commun. 2005)
    9. Proteomics and transcriptomics analyses of secretagogin down-regulation in human non-functional pituitary adenomas. (PubMed id 15237930)1, 9 Zhan X....Desiderio D.M. (Pituitary 2003)
    10. Identification and characterization of secretagogin promoter activity. (PubMed id 17083620)1, 9 Skovhus K.V....Pociot F. (Scand. J. Immunol. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10590 HGNC: 16941 AceView: SCGN Ensembl:ENSG00000079689 euGenes: HUgn10590
    ECgene: SCGN H-InvDB: SCGN

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SCGN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SCGN gene:
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    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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