Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SCGB3A2 Gene

protein-coding   GIFtS: 54
GCID: GC05P147250

Secretoglobin, Family 3A, Member 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Secretoglobin, Family 3A, Member 21 2     Uteroglobin Related Protein 11
Pneumo Secretory Protein 11 2 3     LU1032
Uteroglobin-Related Protein 11 2 3     pnSP-12
UGRP12 3 5     Secretoglobin Family 3A Member 22
PNSP12 3     PnSP-13

External Ids:    HGNC: 183911   Entrez Gene: 1171562   Ensembl: ENSG000001642657   OMIM: 6065315   UniProtKB: Q96PL13   
ORGUL members:         

Export aliases for SCGB3A2 gene to outside databases

Previous GC identifers: GC05P147290 GC05P147840 GC05P147286 GC05P147238 GC05P142405


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SCGB3A2 Gene:
The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid
transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to
asthma.(provided by RefSeq, Mar 2010)

GeneCards Summary for SCGB3A2 Gene:
SCGB3A2 (secretoglobin, family 3A, member 2) is a protein-coding gene. Diseases associated with SCGB3A2 include asthma, and interstitial lung disease. An important paralog of this gene is SCGB3A1.

Gene Wiki entry for SCGB3A2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000005.10  NC_018916.2  NT_029289.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the SCGB3A2 gene promoter:
         Pax-3   POU2F1   Nkx2-2   POU2F1a   Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCGB3A2 promoter sequence
   Search Chromatin IP Primers for SCGB3A2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCGB3A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q32   Ensembl cytogenetic band:  5q32   HGNC cytogenetic band: 5q32

SCGB3A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCGB3A2 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P147250:  view genomic region     (about GC identifiers)

Start:
147,250,245 bp from pter      End:
147,261,756 bp from pter
Size:
11,512 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SG3A2_HUMAN, Q96PL1 (See protein sequence)
Recommended Name: Secretoglobin family 3A member 2 precursor  
Size: 93 amino acids; 10161 Da
Subunit: Homodimer

Explore the universe of human proteins at neXtProt for SCGB3A2: NX_Q96PL1

Explore proteomics data for SCGB3A2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SCGB3A2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_473364.1  
    ENSEMBL proteins: 
     ENSP00000423930   ENSP00000296694  
    Reactome Protein details: Q96PL1

    SCGB3A2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for SCGB3A2
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SCGB3A2
    GenScript Custom Purified and Recombinant Proteins Services for SCGB3A2
    Novus Biologicals SCGB3A2 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SCGB3A2

    SCGB3A2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for SCGB3A2 (UGRP1/SCGB3A2)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SCGB3A2
    Novus Biologicals SCGB3A2 Antibody
    Abcam antibodies for SCGB3A2
    Cloud-Clone Corp. Antibodies for SCGB3A2
    Search ThermoFisher Antibodies for SCGB3A2
    Search LSBio for Antibodies for SCGB3A2

    SCGB3A2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SCGB3A2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SCGB3A2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SCGB3A2
    Cloud-Clone Corp. CLIAs for SCGB3A2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    SCGB: Secretoglobins

    1 InterPro protein domain:
     IPR016126 Secretoglobin

    Graphical View of Domain Structure for InterPro Entry Q96PL1

    ProtoNet protein and cluster: Q96PL1

    UniProtKB/Swiss-Prot: SG3A2_HUMAN, Q96PL1
    Similarity: Belongs to the secretoglobin family. UGRP subfamily


    SCGB3A2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    SCGB3A2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SCGB3A2:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SCGB3A2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SCGB3A2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SCGB3A2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SCGB3A2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SCGB3A2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SCGB3A2
    SwitchGear 3'UTR luciferase reporter plasmidSCGB3A2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SCGB3A2
    Predesigned siRNA for gene silencing in human, mouse, rat SCGB3A2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SCGB3A2

    Clone
    Products:
         
    OriGene clones in human, mouse for SCGB3A2 (see all 6)
    OriGene ORF clones in mouse, rat for SCGB3A2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SCGB3A2 (NM_054023)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCGB3A2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB3A2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SCGB3A2
    Browse ESI BIO Cell Lines and PureStem Progenitors for SCGB3A2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCGB3A2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SG3A2_HUMAN, Q96PL1: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0071682endocytic vesicle lumen TAS--

    SCGB3A2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for SCGB3A2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Binding and Uptake of Ligands by Scavenger Receptors
    Binding and Uptake of Ligands by Scavenger Receptors0.53
    Scavenging by Class A Receptors0.00

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SCGB3A2
        Scavenging by Class A Receptors



    SCGB3A2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SCGB3A2
    Interactions:

        GeneGlobe Interaction Network for SCGB3A2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SCGB3A2 (Q96PL13 ENSP000002966944) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MARCOQ9UEW33, ENSP000003189164I2D: score=2 STRING: ENSP00000318916
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SCGB3A2 (SG3A2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SCGB3A2 gene: 
    NM_054023.4  

    Unigene Cluster for SCGB3A2:

    Secretoglobin, family 3A, member 2
    Hs.483765  [show with all ESTs]
    Unigene Representative Sequence: BI518636
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000504320 ENST00000507160 ENST00000514688 ENST00000296694(uc003lot.2)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SCGB3A2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SCGB3A2
    SwitchGear 3'UTR luciferase reporter plasmidSCGB3A2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SCGB3A2
    Predesigned siRNA for gene silencing in human, mouse, rat SCGB3A2
    Clone
    Products:
         
    OriGene clones in human, mouse for SCGB3A2 (see all 6)
    OriGene ORF clones in mouse, rat for SCGB3A2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SCGB3A2 (NM_054023)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCGB3A2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB3A2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SCGB3A2
    OriGene qSTAR qPCR primer pairs in human, mouse for SCGB3A2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCGB3A2
      QuantiTect SYBR Green Assays in human, mouse, rat SCGB3A2
      QuantiFast Probe-based Assays in human, mouse, rat SCGB3A2

    Additional mRNA sequence: 

    AF313455.1 AF439545.1 AY358979.1 BC024232.1 

    3 DOTS entries:

    DT.213241  DT.100746709  DT.95158474 

    Selected AceView cDNA sequences (see all 69):

    BE552278 AA358271 AI695085 BE218717 BE222065 AF313455 AI693419 BF111035 
    AI193016 AA988559 AI355302 BC024232 AI355612 AI298558 AI354759 AI265819 
    BE328852 AA988921 D31079 AW449467 AI263451 D30979 AY358979 AI668642 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SCGB3A2 expression in normal human tissues (normalized intensities)      SCGB3A2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGCTGGTAA
    SCGB3A2 Expression
    About this image


    SCGB3A2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 9 entries
             Human embryonic stem cells (family)
             ESI-051   
     
     Lung (Respiratory System)    fully expand to see all 5 entries
             Proximal Lung Epithelial Cells Stem Bronchi
             Trachea
             Lung Epithelial Progenitors
             Human Pulmonary Alveolar Epithelial Cells (HPAEpiC)   
             bronchoalveolar lavage cells   
     
     Epithelial Cells
             Proximal Lung Epithelial Cells Stem Bronchi
             Human Pulmonary Alveolar Epithelial Cells (HPAEpiC)   
     
     NULL (Uncategorized)
             Vascular endothelial growth factor-induced cells
    SCGB3A2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SCGB3A2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.483765

    UniProtKB/Swiss-Prot: SG3A2_HUMAN, Q96PL1
    Tissue specificity: Highly expressed in lung

        Custom PCR Arrays for SCGB3A2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SCGB3A2
    OriGene qSTAR qPCR primer pairs in human, mouse for SCGB3A2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCGB3A2
    QuantiTect SYBR Green Assays in human, mouse, rat SCGB3A2
    QuantiFast Probe-based Assays in human, mouse, rat SCGB3A2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCGB3A2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of human and mouse.

    Orthologs for SCGB3A2 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scgb3a21 , 5 secretoglobin, family 3A, member 21, 5 79.76(n)1
    79.76(a)1
      18 (23.49 cM)5
    1171581  NM_054038.11  NP_473379.11 
     437643275 


    ENSEMBL Gene Tree for SCGB3A2 (if available)
    TreeFam Gene Tree for SCGB3A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SCGB3A2 gene
    SCGB3A12  
    2 SIMAP similar genes for SCGB3A2 using alignment to 2 protein entries:     SG3A2_HUMAN (see all proteins):
    UGRP1    SCGB3A1

    SCGB3A2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SCGB3A2 (see all 185)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361854
    A breast cancer sample4--see VAR_0361852 K N mis40--------
    rs32173721,2
    C--147258536(+) TTGTA-/TTTTTT 1 -- int10--------
    rs1859307041,2
    --147531964(+) AAGGGC/TGTCAT 1 -- us2k10--------
    rs732613681,2
    C,F--147532073(+) TGCCTG/AAGTAG 1 -- us2k14Minor allele frequency- A:0.18WA CSA 124
    rs743197951,2
    C,F--147532100(+) AAACAA/GACCCG 1 -- us2k11Minor allele frequency- G:0.09WA 118
    rs732613721,2
    C,F--147532118(+) CCTACC/GTGGGC 1 -- us2k12Minor allele frequency- G:0.25WA 120
    rs797170831,2
    C,F--147532145(+) CTGATT/AGAGTG 1 -- us2k11Minor allele frequency- A:0.06WA 118
    rs1906441591,2
    --147532184(+) TACCAA/GGACCC 1 -- us2k10--------
    rs1437831251,2
    C--147532190(+) GACCCA/GTGTAA 1 -- us2k10--------
    rs1832421031,2
    C--147532227(+) CCACTA/GGTTAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SCGB3A2 (147250245 - 147261756 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SCGB3A2: --
    Human Gene Mutation Database (HGMD): SCGB3A2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SCGB3A2
    DNA2.0 Custom Variant and Variant Library Synthesis for SCGB3A2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 606531   
    OMIM disorders: 600807  
    8 diseases for SCGB3A2:    About MalaCards
    asthma    interstitial lung disease    rhinitis    allergic rhinitis
    graves' disease    thyroiditis    breast and colorectal cancer    colorectal cancer

    1 disease from the University of Copenhagen DISEASES database for SCGB3A2:
    Asthma

    SCGB3A2 for disorders           About GeneDecksing

    4 Novoseek inferred disease relationships for SCGB3A2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    asthma allergic 67.7 7 15591807 (2), 18201431 (2), 17218572 (2), 12859445 (1)
    asthma 52.8 35 18089940 (5), 17218572 (5), 12915772 (3), 12859445 (1) (see all 6)
    genetic susceptibility 49.8 2 15591807 (1), 18201431 (1)
    inflammation 0 3 11682631 (1), 15485815 (1)

    Genetic Association Database (GAD): SCGB3A2
    Human Genome Epidemiology (HuGE) Navigator: SCGB3A2 (9 documents)

    Export disorders for SCGB3A2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SCGB3A2 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with SCGB3A2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. UGRP1, a uteroglobin/Clara cell secretory protein-related protein, is a novel lung-enriched downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor. (PubMed id 11682631)1, 2, 3, 9 Niimi T....Kimura S. (Mol. Endocrinol. 2001)
    2. Plasma UGRP1 levels associate with promoter G-112A polymorphism and the severity of asthma. (PubMed id 18089940)1, 4, 9 Inoue K....Munakata M. (Allergol Int 2008)
    3. Uteroglobin-related protein 1(UGRP1) gene polymorphisms and atopic asthma in the Indian population. (PubMed id 15591807)1, 4, 9 Batra J....Ghosh B. (Int. Arch. Allergy Immunol. 2005)
    4. A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma. (PubMed id 11813133)1, 4, 9 Niimi T....Kimura S. (Am. J. Hum. Genet. 2002)
    5. Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily. (PubMed id 22155607)1, 3 Jackson B.C....Vasiliou V. (Hum. Genomics 2011)
    6. Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease. (PubMed id 20210668)1, 4 Simmonds M.J....Gough S.C. (Thyroid 2010)
    7. Analyses of associations with asthma in four asthma population samples from Canada and Australia. (PubMed id 19247692)1, 4 Daley D....Hudson T.J. (Hum. Genet. 2009)
    8. Functional SNPs in the SCGB3A2 promoter are associated with susceptibility to Graves' disease. (PubMed id 19126779)1, 4 Song H.D....Chen J.L. (Hum. Mol. Genet. 2009)
    9. Association study between the IL4, IL13, IRF1 and UGRP1 genes in chromosomal 5q31 region and Chinese Graves' disease. (PubMed id 16195814)1, 4 Yang Y....Weiping T. (J. Hum. Genet. 2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 117156 HGNC: 18391 AceView: SCGB3A2 Ensembl:ENSG00000164265 euGenes: HUgn117156
    ECgene: SCGB3A2 H-InvDB: SCGB3A2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SCGB3A2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SCGB3A2 gene:
    Search GeneIP for patents involving SCGB3A2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Antibodies for SCGB3A2 (UGRP1/SCGB3A2)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SCGB3A2  
     OriGene qPCR primer pairs and template standards for SCGB3A2   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SCGB3A2  
     OriGene qSTAR qPCR primer pairs in human, mouse for SCGB3A2   OriGene Purified Protein for SCGB3A2  
     OriGene ORF clones in mouse, rat for SCGB3A2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SCGB3A2   OriGene Custom Protein Services for SCGB3A2  

     
     
     Block miRNA regulation of human, mouse, rat SCGB3A2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SCGB3A2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCGB3A2 Predesigned siRNA for gene silencing in human, mouse, rat SCGB3A2
     QuantiFast Probe-based Assays in human, mouse, rat SCGB3A2 QuantiTect SYBR Green Assays in human, mouse, rat SCGB3A2
     Custom PCR Arrays for SCGB3A2 Search Chromatin IP Primers for SCGB3A2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCGB3A2  GeneGlobe Interaction Network for SCGB3A2
     Regulatory tfbs in SCGB3A2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SCGB3A2 GenScript cDNA clones with any tag delivered in your preferred vector for SCGB3A2
     GenScript Custom Assay Services for SCGB3A2 GenScript Custom overexpressing Cell Line Services for SCGB3A2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SCGB3A2 (SG3A2)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SCGB3A2 antibodies
     SCGB3A2 proteins
     Antibodies for SCGB3A2
     See all of Abcam's Antibodies, Kits and Proteins for SCGB3A2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SCGB3A2
     Antibodies for SCGB3A2
     ELISAs for SCGB3A2
     CLIAs for SCGB3A2



     Browse ESI BIO Cell Lines and PureStem Progenitors for SCGB3A2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCGB3A2
     SwitchGear 3'UTR luciferase reporter plasmids for SCGB3A2
     SwitchGear Promoter luciferase reporter plasmids for SCGB3A2
     Search ThermoFisher Antibodies for SCGB3A2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB3A2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SCGB3A2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SCGB3A2
     Search LSBio for Antibodies for SCGB3A2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SCGB3A2 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4