SCGB2B2 Gene
protein-coding GIFtS: 35
GCID: GC19M035085
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secretoglobin, family 2B, member 2(Previous name: secretoglobin-like )
(Previous symbol: SCGBL)
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Aliases
for SCGB2B2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Secretoglobin, Family 2B, Member 21 2 | | SCGB4A21 2 3 | | SCGBL1 2 3 | | Secretoglobin-Like Protein2 3 | | Secretoglobin-Like1 | | Secretoglobin Family 2B Member 22 |
Export aliases for SCGB2B2 gene to outside databases |
Summaries
for SCGB2B2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SCGB2B2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SCGB2B2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SCGB2B2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCGB2B2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.11 Ensembl cytogenetic band: 19q13.11 HGNC cytogenetic band: 19q13.12SCGB2B2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M035085: view genomic region
(about GC identifiers)
Start:
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35,084,346 bp from pter |
End:
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35,085,490 bp from pter |
Size:
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1,145 bases |
Orientation:
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minus strand |
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Proteins
for SCGB2B2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SC2B2_HUMAN, Q4G0G5 (See
protein sequence)Recommended Name: Secretoglobin family 2B member 2 precursor Size: 96 amino acids; 10563 Da
Subcellular location: Secreted (Potential)Explore the universe of human proteins at neXtProt for SCGB2B2: NX_Q4G0G5
SCGB2B2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001020762.1
ENSEMBL proteins: ENSP00000368502
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
SCGB2B2 for ontologies About GeneDecksing
SCGB2B2 Antibody Products:
Assay Products for SCGB2B2: |
Protein
Domains /
Families
for SCGB2B2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SCGB2B2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q4G0G5ProtoNet protein and cluster: Q4G0G5 UniProtKB/Swiss-Prot: SC2B2_HUMAN, Q4G0G5Similarity: Belongs to the secretoglobin family |
Function
for SCGB2B2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB2B2
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB2B2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for SCGB2B2 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCGB2B2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB2B2 |
1 GenomeRNAi human phenotype for SCGB2B2:
|
Pathways & Interactions
for SCGB2B2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SCGB2B2
|
Drugs & Compounds
for SCGB2B2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SCGB2B2
Search CenterWatch for drugs/clinical trials and news about SCGB2B2 / SC2B2
|
Transcripts
for SCGB2B2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SCGB2B2 gene: NM_001025591.2 Unigene Cluster for SCGB2B2: Secretoglobin, family 2B, member 2 Hs.656990 [show with all ESTs]Unigene Representative Sequence: AK0934951 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000379204(uc002nvn.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB2B2
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB2B2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for SCGB2B2 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCGB2B2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB2B2 |
Additional cDNA sequence: AK093495.1 BC093909.1 BC093935.1 2 DOTS entries: DT.100013512 DT.97798898 24/32 AceView cDNA sequences (see all 32): CR603799 AI422604 AX748165 AA290868 BQ188834 AA481857 BX105421 AI868886 AI472323 AW576434 AK093495 BM984683 BX342528 CA429783 AW501472 AW139287 BX501275 AI073890 BX342527 BM716941 T16687 BX470939 BX490537 CA439245
GeneLoc Exon Structure
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Expression
for SCGB2B2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SCGB2B2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGGTGACAT
About this image
See SCGB2B2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SCGB2B2
SOURCE GeneReport for Unigene cluster: Hs.656990
SABiosciences Custom PCR Arrays for SCGB2B2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCGB2B2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat SCGB2B2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCGB2B2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCGB2B2 |
Orthologs
for SCGB2B2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for SCGB2B2 (if available)
TreeFam Gene Tree for SCGB2B2 (if available) |
Paralogs
for SCGB2B2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SCGB2B2 gene
SCGB2B2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for SCGB2B2
PGOHUM00000234663
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Genomic Variants
for SCGB2B2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SCGB2B2 (35084346 - 35085490 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SCGB2B2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCGB2B2 |
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Disorders
/ Diseases
for SCGB2B2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 SCGB2B2 for disorders About MalaCards
SCGB2B2 for disorders About GeneDecksing
OMIM gene information: 615063
OMIM disorders: --
Export disorders for SCGB2B2 gene to outside databases
|
Publications
for SCGB2B2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SCGB2B2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SCGB2B2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Update of the human secretoglobin (SCGB) gene superfa mily and an example of 'evolutionary bloom' of androgen-binding protein genes w ithin the mouse Scgb gene superfamily. (PubMed id 22155607)1, 3 Jackson B.C....Vasiliou V. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for SCGB2B2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SCGB2B2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SCGB2B2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SCGB2B2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SCGB2B2 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for SCGB2B2 gene:
Search GeneIP for patents involving SCGB2B2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SCGB2B2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SCGB2B2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SCGB2B2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCGB2B2 | | | OriGene Protein Over-expression Lysate for SCGB2B2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SCGB2B2 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB2B2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB2B2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SCGB2B2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCGB2B2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCGB2B2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SCGB2B2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCGB2B2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCGB2B2 |
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 | | | SCGB2B2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for SCGB2B2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB2B2 |
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