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Aliases for SCGB2B2 Gene

Aliases for SCGB2B2 Gene

  • Secretoglobin Family 2B Member 2 2 3
  • Secretoglobin, Family 2B, Member 2 3 5
  • Secretoglobin-Like Protein 3 4
  • SCGB4A2 3 4
  • SCGBL 3 4
  • Secretoglobin-Like 2

External Ids for SCGB2B2 Gene

Previous HGNC Symbols for SCGB2B2 Gene

  • SCGBL

Previous GeneCards Identifiers for SCGB2B2 Gene

  • GC19M035085

Summaries for SCGB2B2 Gene

GeneCards Summary for SCGB2B2 Gene

SCGB2B2 (Secretoglobin Family 2B Member 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SCGB2B2 Gene

Genomics for SCGB2B2 Gene

Genomic Location for SCGB2B2 Gene

Chromosome:
19
Start:
34,576,740 bp from pter
End:
34,675,731 bp from pter
Size:
98,992 bases
Orientation:
Minus strand

Genomic View for SCGB2B2 Gene

Genes around SCGB2B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCGB2B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCGB2B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCGB2B2 Gene

No data available for Regulatory Elements for SCGB2B2 Gene

Proteins for SCGB2B2 Gene

  • Protein details for SCGB2B2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4G0G5-SC2B2_HUMAN
    Recommended name:
    Secretoglobin family 2B member 2
    Protein Accession:
    Q4G0G5

    Protein attributes for SCGB2B2 Gene

    Size:
    96 amino acids
    Molecular mass:
    10563 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SCGB2B2 Gene

Proteomics data for SCGB2B2 Gene at MOPED

Post-translational modifications for SCGB2B2 Gene

No Post-translational modifications

Other Protein References for SCGB2B2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SCGB2B2 Gene

Domains & Families for SCGB2B2 Gene

Gene Families for SCGB2B2 Gene

Protein Domains for SCGB2B2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SCGB2B2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q4G0G5

UniProtKB/Swiss-Prot:

SC2B2_HUMAN :
  • Belongs to the secretoglobin family.
Family:
  • Belongs to the secretoglobin family.
genes like me logo Genes that share domains with SCGB2B2: view

Function for SCGB2B2 Gene

Phenotypes for SCGB2B2 Gene

GenomeRNAi human phenotypes for SCGB2B2:
genes like me logo Genes that share phenotypes with SCGB2B2: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SCGB2B2 Gene

Localization for SCGB2B2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SCGB2B2 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SCGB2B2 Gene COMPARTMENTS Subcellular localization image for SCGB2B2 gene
Compartment Confidence
extracellular 5

No data available for Gene Ontology (GO) - Cellular Components for SCGB2B2 Gene

Pathways & Interactions for SCGB2B2 Gene

SuperPathways for SCGB2B2 Gene

No Data Available

Interacting Proteins for SCGB2B2 Gene

Gene Ontology (GO) - Biological Process for SCGB2B2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SCGB2B2 Gene

Drugs & Compounds for SCGB2B2 Gene

No Compound Related Data Available

Transcripts for SCGB2B2 Gene

mRNA/cDNA for SCGB2B2 Gene

Unigene Clusters for SCGB2B2 Gene

Secretoglobin, family 2B, member 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SCGB2B2 Gene

No ASD Table

Relevant External Links for SCGB2B2 Gene

GeneLoc Exon Structure for
SCGB2B2
ECgene alternative splicing isoforms for
SCGB2B2

Expression for SCGB2B2 Gene

mRNA expression in normal human tissues for SCGB2B2 Gene

mRNA differential expression in normal tissues according to GTEx for SCGB2B2 Gene

This gene is overexpressed in Testis (x4.8).

SOURCE GeneReport for Unigene cluster for SCGB2B2 Gene Hs.656990

genes like me logo Genes that share expression patterns with SCGB2B2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SCGB2B2 Gene

Orthologs for SCGB2B2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for SCGB2B2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SCGBL 35
  • 96.47 (n)
  • 92.94 (a)
SCGB2B2 36
  • 96 (a)
OneToOne
Species with no ortholog for SCGB2B2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SCGB2B2 Gene

ENSEMBL:
Gene Tree for SCGB2B2 (if available)
TreeFam:
Gene Tree for SCGB2B2 (if available)

Paralogs for SCGB2B2 Gene

Pseudogenes.org Pseudogenes for SCGB2B2 Gene

genes like me logo Genes that share paralogs with SCGB2B2: view

No data available for Paralogs for SCGB2B2 Gene

Variants for SCGB2B2 Gene

Sequence variations from dbSNP and Humsavar for SCGB2B2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs372676 -- 34,614,463(+) ttttt(A/T)aatta intron-variant
rs733998 -- 34,635,700(-) TCACA(C/T)TGGAG intron-variant
rs751792 -- 34,666,349(+) CACAC(A/G)CTCCC intron-variant
rs404355 -- 34,612,270(+) ctgac(A/G)tcgtg intron-variant
rs404899 -- 34,630,623(+) GTGCT(A/G)GAGAG intron-variant

Variation tolerance for SCGB2B2 Gene

Residual Variation Intolerance Score: 77.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.25; 5.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SCGB2B2 Gene

HapMap Linkage Disequilibrium report
SCGB2B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SCGB2B2 Gene

Disorders for SCGB2B2 Gene

Relevant External Links for SCGB2B2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SCGB2B2

No disorders were found for SCGB2B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SCGB2B2 Gene

Publications for SCGB2B2 Gene

  1. Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily. (PMID: 22155607) Jackson B.C. … Vasiliou V. (Hum. Genomics 2011) 2 3 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SCGB2B2 Gene

Sources for SCGB2B2 Gene

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